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27Th ANNUAL RESEARCH DAY & Henderson Lecture 27th ANNUAL RESEARCH DAY & Henderson Lecture FRIDAY, MAY 7, 2010 8:00 a.m. to 6:30 p.m. Northrop Frye Hall, Ground Floor Victoria University, 73 Queen's Park Crescent East University of Toronto M5S 1K7 Lecturer: Jane Norman MD Professor of Maternal and Fetal Health, University of Edinburgh, UK Co-Director, Edinburgh Tommy’s Centre for Maternal and Fetal Health Research Topic: Being Born Too Soon – Do Obstetricians Have Anything To Offer? Abstract deadline: Friday, March 5, 2010 http://www.obgyn.utoronto.ca/Research/ResearchDay.htm For additional information or assistance, please contact Helen Robson at [email protected] PROGRAMME-AT-A-GLANCE (A.M.) Department of Obstetrics & Gynaecology 27th Annual Research Day, Friday, May 7, 2010 Northrop Frye Hall, Victoria University, University of Toronto, 73 Queen’s Park Crescent NF=Northrop Frye Hall Burwash Hall is located at the north end of the Victoria Quad 7:30 a.m. on Poster Set-up for Poster Session I [NF, ground floor, Rms. 004, 006, 007 & 008] 8:00 a.m. Registration & Continental Breakfast [NF, ground floor lobby] 8:25 – 8:30 a.m. Welcome: Dr. Alan Bocking, Chair [NF, ground floor Lecture Hall, Rm. 003] 8:30 – 9:45 a.m. Oral Session I (O1-O5) [NF, ground floor Lecture Hall, Rm. 003] 9:45 – 10:05 a.m. Coffee Break & Poster Session I Walkabout [NF, ground floor lobby; Rms. 004, 006, 007 & 008] 10:05 – 11:05 a.m. Poster Session I Tour [NF, Rms. 004, 006, 007 & 008] Groups A-F Poster Takedown for a.m. session Until 2:50 p.m. Poster Set-up for p.m. session [NF, Rms. 004, 006, 007 & 008] 11:10 – 12:10 Oral Session II (O6-O9) [NF, ground floor Lecture Hall, Rm. 003] 12:15 – 1:15 p.m. Lunch [Dining Room, Burwash Hall] DRAFT PROGRAMME-AT-A-GLANCE (P.M.) NF=Northrop Frye Hall Burwash Hall is located at the north end of the Victoria Quad 1:20 – 2:50 p.m. Oral Session III (O10-O15) [NF, ground floor Lecture Hall, Rm. 003] 2:50 – 3:10 p.m. Coffee Break & Poster Session II Walkabout [NF, ground floor lobby, Rms. 004, 006, 007 & 008] 3:10 – 4:10 p.m. Poster Session II [NF, Rms. 004, 006, 007 & 008] Groups G-L Poster Takedown 4:15 – 5:15 p.m. Henderson Lecture [NF, ground floor Lecture Hall, Rm. 003] Jane Norman MD Professor of Maternal and Fetal Health, University of Edinburgh, UK Co-Director, Edinburgh Tommy’s Centre for Maternal and Fetal Health Research Topic: “Being born too soon – do obstetricians have anything to offer?” 5:15 – 5:20 p.m. Closing Remarks: Dr. Alan Bocking [NF, ground floor Lecture Hall, Rm. 003] 5:25 – 6:30 p.m. Wine & Cheese Reception and JW Knox Ritchie Research Awards & Papsin Award Presentations [Dining Room, Burwash Hall] 27th Annual RESEARCH DAY FRIDAY, MAY 7, 2010 8:00 a.m. – 6:30 p.m. Northrop Frye Hall, Ground Floor Victoria University, 73 Queen’s Park Cres East University of Toronto HENDERSON LECTURE: 4:15 p.m. – 5:15 p.m. “Being born too soon – do obstetricians have anything to offer?” Dr. Jane Norman Professor of Maternal and Fetal Health, University of Edinburgh, UK Co-Director, Edinburgh Tommy’s Centre for Maternal and Fetal Health Research WINE & CHEESE RECEPTION: 5:25 – 6:30 P.M. We gratefully acknowledge the sponsorship of: ABBOTT LABORATORIES LTD. BAYER HEALTHCARE PHARMACEUTICALS BOEHRINGER-INGELHEIM (CANADA) LTD. FERRING PHARMACEUTICALS GLAXOSMITHKLINE INC. MERCK FROSST CANADA LTD. in support of our 27th Annual Research Day. 27th ANNUAL RESEARCH DAY Friday May 7, 2010 TABLE OF CONTENTS Page 1. Maps …… 2, 3 2. Programme-at-a-Glance .…... 4 3. Programme .…... 7 4. – Oral Sessions I & II (a.m.) .….. 7, 16 5. – Poster Session I (a.m.) .….. 9 6. – Oral Session III (p.m.) .….. 17 7. – Poster Session II (p.m.) .….. 18 8. Henderson Lecture, Bio .….. 25, 26 9. Awards .…... 27 10. Oral Abstracts .….. 29 11. Poster Abstracts .…... 47 12. Index of Presenters – by Last Name .…... 114 – by Abstract # & Session .…... 117 Dining Hall Entrance=X Northrop Frye Hall 73 Queen's Park Cres. East 4 RESEARCH DAY 2010 PROGRAMME-AT-A-GLANCE (A.M.) NF=Northrop Frye Hall Burwash Hall is located at the north end of the Victoria Quad 7:30 a.m. on Poster Set-up for Poster Session I [NF, ground floor, Rms. 004, 006, 007 & 008] 8:00 a.m. Registration & Continental Breakfast [NF, ground floor lobby] 8:25 – 8:30 a.m. Welcome: Dr. Alan Bocking, Chair [NF, ground floor Lecture Hall, Rm. 003] 8:30 – 9:45 a.m. Oral Session I (O1-O5) [NF, ground floor Lecture Hall, Rm. 003] Chair: Dr. Theodore J Brown; Judges: Drs. Isabella Caniggia & Rose Kung 9:45 – 10:05 a.m. Coffee Break & Poster Session I Walkabout [NF, ground floor lobby; Rms. 004, 006, 007 & 008] 10:05 – 11:05 a.m. Poster Session I Tour [NF, Rms. 004, 006, 007 & 008] Groups A-F Group: Chairs/Judges; Judge A: Drs. Stephane Laframboise & Stephen Lye; Dr. Sarah Ferguson B: Drs. Rory Windrim & Stephen Matthews; Dr. Evelyn Lambe C: Drs. S Lee Adamson & John Kingdom; Dr. Rachel Kupets D: Drs. Robert Casper & Navid Esfandiari; Dr. Fay Weisberg E: Drs. Ori Nevo & Theodore J Brown; Dr. Andrea Lausman F: Dr. Howard Berger & Harold Drutz; Dr. Elliott Lyons Poster Takedown for a.m. session Until 2:50 p.m. Poster Set-up for p.m. session [NF, ground floor, Rms. 004, 006, 007 & 008] 11:10 – 12:10 Oral Session II (O6-O9) [NF, ground floor Lecture Hall, Rm. 003] Chair: Dr. May Alarab; Judges: Drs. S Lee Adamson & Sony Sierra 12:15 – 1:15 p.m. Lunch [Dining Room, Burwash Hall] 5 RESEARCH DAY 2010 PROGRAMME-AT-A-GLANCE (P.M.) NF=Northrop Frye Hall Burwash Hall is located at the north end of the Victoria Quad 1:20 – 2:50 p.m. Oral Session III (O10-O15) [NF, ground floor Lecture Hall, Rm. 003] Chair: Dr. Andrea Jurisicova; Judges: Drs. P Gareth Seaward & Marcus Bernardini 2:50 – 3:10 p.m. Coffee Break & Poster Session II Walkabout [NF, ground floor lobby, Rms. 004, 006, 007 & 008] 3:10 – 4:10 p.m. Poster Session II [NF, Rms. 004, 006, 007 & 008] Groups G-L Group: Chairs/Judges; Judge G: Drs. Isabella Caniggia & Clifford Librach; Drs. Ellen Greenblatt & Robert Casper H: Drs. Andrea Jurisicova & Kellie Murphy; Dr. Richard Pittini I: Drs. Theodore J Brown & Allan Covens; Dr. Jason Dodge J: Drs. John Kingdom & Rose Kung; Dr. Kimberly Liu K: Drs. Wendy Whittle & Mark Yudin; Dr. Michael Shier L: Drs. Adrian Brown & Prati Sharma; Dr. Cynthia Maxwell Poster Takedown 4:15 – 5:15 p.m. Henderson Lecture [NF, ground floor Lecture Hall, Rm. 003] Dr. Jane Norman Professor of Maternal and Fetal Health, University of Edinburgh, UK Co-Director, Edinburgh Tommy’s Centre for Maternal and Fetal Health Research Topic: “Being born too soon – do obstetricians have anything to offer?” 5:15 – 5:20 p.m. Closing Remarks: Dr. Alan Bocking [NF, ground floor Lecture Hall, 003] 5:25 – 6:30 p.m. Wine & Cheese Reception and JW Knox Ritchie Research Awards & Papsin Award Presentations [Dining Room, Burwash Hall] 6 7 PROGRAMME 27TH ANNUAL RESEARCH DAY Friday May 7, 2010 Northrop Frye Hall, Ground Floor Victoria University, 73 Queen's Park Crescent East University of Toronto 7:30 a.m. on Poster Set-up for Poster Session I [NF, ground floor, Rms. 004, 006, 007 & 008] 8:00 a.m. Registration & Continental Breakfast [NF, ground floor lobby] 8:25 – 8:30 a.m. Welcome: Dr. Alan Bocking, Chair [NF, ground floor Lecture Hall, Rm. 003] 8:30 – 9:45 a.m. Oral Session I (O1-O5) 8:30 – 9:45 a.m. ORAL SESSION I Oral Session I (O1-O5) (5 presentations @15 minutes: 10 minute presentation + 5 minutes for questions) [NF, ground floor Lecture Hall, Rm. 003] Chair/Judge: Dr. Theodore J Brown Judges: Drs. Isabella Caniggia & Rose Kung 8:30-8:45 O1 EFFECT OF REDUCED PLACENTAL EXPRESSION OF GLIAL CELL MISSING-1 ON PREGNANCY OUTCOME. Shannon A Bainbridge[PD](1), Kathie J Whiteley (1), Dawei Qu (1), John CP Kingdom (1,2) and S Lee Adamson (1,2,3). (1) Samuel Lunenfeld Research Institute, Mount Sinai Hospital, (2) Department of Obstetrics & Gynaecology, Mount Sinai Hospital, (2) Department of Physiology, University of Toronto. 8:45-9:00 O2 CORTICOSTEROIDS INCREASE P-GLYCOPROTEIN FUNCTION IN PRIMARY GUINEA PIG BRAIN ENDOTHELIAL CELLS Majid Iqbal[G](1),William Gibb(4),Stephen G Matthews(1,2,3 (1) Departments of (1)Physiology, (2)Obstetrics and Gynaecology and (3)Medicine, Faculty of Medicine, University of Toronto, Medical, Ontario, Canada. Department of Obstetrics and 8 9:00-9:15 O3 THE “DUC” TRIAL: A PILOT RANDOMIZED CONTROLLED TRIAL OF IMMEDIATE VS. DELAYED CORD CLAMPING IN PRETERM INFANTS BORN BETWEEN 24 AND 32 WEEKS’ GESTATION Kelly S Chu [R](1), Kellie E Murphy(1,3), Wendy L Whittle(1,3), Rory Windrim(1,3), Prakesh Shah(2,4) University of Toronto, Department of Obstetrics/Gynaecology (1), University of Toronto, Department of Paediatrics (2), Department of Maternal-Fetal Medicine, Mount Sinai Hospital (3), Department of Paediatrics, Mount Sinai Hospital (4). 9:15-9:30 O4 EXPRESSION OF ENZYMES REGULATING EXTRACELLULAR MATRIX BIOGENESIS IN VAGINAL TISSUE OF WOMEN WITH AND WITHOUT PELVIC ORGAN PROLAPSE Maria Bortolini [F](1,4), Oksana Shynlova (1), Nadiya Oleksiv(1), Harold Drutz, (2,4), Stephen Lye (1,2,3), May Alarab (1,4) (1)Samuel Lunenfeld Research Institute, Mount Sinai Hospital, (2)Ob/Gyn;(3)Physiology and (4)Urogynaecology, Mount Sinai Hospital, University of Toronto.
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