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Alliance for Case Studies for Global Health Case Studies for Global Health Building relationships. Sharing knowledge. Alliance for Case Studies for Global Health ® www.casestudiesforglobalhealth.org Case Studies for Global Health Building relationships. Sharing knowledge. Case Studies for Global Health Case Studies for Global Health: Building relationships. Sharing knowledge. ISBN #0-9778444-8-X Copyright ©2009 by the Alliance for Case Studies for Global Health The logos of the Bill & Melinda Gates Foundation, International AIDS Vaccine Institute (IAVI), Association of University Technology Managers (AUTM), Global Health Progress and TDR are the trademark of the respective organizations. All rights reserved. This material may be quoted or reproduced without charge for noncommercial purposes only; please acknowledge source. This publication does not imply endorsement by the Alliance for Case Studies for Global Health of any product or service, nor any organization, corporation or institution. Case Studies for Global Health is available in electronic format and limited print copies are available. You may download a copy of the book or individual case studies at: www.casestudiesforglobalhealth.org. All other inquiries: Managing Editor Alliance for Case Studies for Global Health 111 Deer Lake Road, Suite 100 Deerfield, IL 60015 USA Web site: www.casestudiesforglobalhealth.org E-mail: [email protected] Printed in the USA on FSC-certified paper. Methods and Acknowledgement This publication is an initiative of the Alliance for Case Studies We reached out to many universities, organizations, companies for Global Health, a collaboration of the Association of University and governments to identify potential case studies. To capture as Technology Managers (AUTM), the Bill & Melinda Gates many diverse stories as possible, we published a call for case studies Foundation, Global Health Progress, the International AIDS in various newsletters, journals and on Web sites during the fall Vaccine Initiative (IAVI) and Tropical Disease Research (TDR). of 2008, which generated considerable interest and a significant The alliance members conceived of this multisector case study number of submissions. initiative in December 2007. Over the following nine months, representatives from each organization shaped our vision of the In February 2009, we established a selection committee made scope and nature of this publication. We rested on the following up of representatives from the five Alliance members, along with objectives for the case studies: a representative of BIO Ventures for Global Health and several global health experts from Africa and India. The members of • They would be solicited from a wide range of stakeholders the committee selected a total of 32 case studies based on their within global health (e.g., private funders, multilateral adherence to the core themes, framework and objectives of the organizations, academia, pharmaceutical and biotech companies, initiative. product development partnerships, and governments) and reflect current transactions and relationships. During the following months, the case studies were developed and written with the help of many individuals and organizations, • They would illustrate how people, organizations, companies including those involved in each partnership; this book would not and governments have worked together to try to solve a have been possible without them taking the time to share their global health challenge. The wide range of potential topics experiences, challenges and successes. would include the complexity of intellectual property, length and stage of product development, costs and nature The result is the set of stories contained in this publication, which of manufacturing, purchasers and markets, financing represent a wide range of stakeholders, activities and approaches. mechanisms, regulatory issues, capacity building, delivery We would like to acknowledge the following organizations and mechanisms, and adoption hurdles. individuals for their many hours of hard work and dedication. • They would provide information on current practices and lessons learned in the course of conducting business and structuring partnerships. www.casestudiesforglobalhealth.org Case Studies for Global Health 5 (As of October 2009) Organizations Within the Alliance for Case Studies for Global Health Association of University Technology Managers (AUTM) – International AIDS Vaccine Initiative (IAVI) – Labeeb Vicki Loise, Executive Director; Jon Soderstrom, Ph.D., Abboud, Senior Vice President & General Counsel: IAVI is an Immediate Past President: AUTM is a global network of international not-for-profit organization whose mission is to ensure more than 3,500 technology transfer professionals who work the development of safe, effective, accessible prophylactic AIDS in academic, research, government, legal and commercial vaccines for use throughout the world. IAVI is headquartered in the settings. AUTM is dedicated to promoting and supporting United States, with regional offices in Amsterdam, Delhi, Nairobi technology transfer through education, advocacy, networking and and Johannesburg, and operates in 25 countries. IAVI works in communication. partnership with governments, civil society, academic institutions and industry in its research and development, advocacy and policy Bill & Melinda Gates Foundation – Erik Iverson, Associate activities. General Counsel, Global Health Program; Jennifer Haberman, Paralegal, Global Health Program: Guided by the belief that Special Programme for Research and Training in Tropical every life has equal value, the Bill & Melinda Gates Foundation Diseases (TDR) – Solomon Nwaka, Leader, Drug Discovery works to help all people lead healthy, productive lives. In for Infectious Tropical Diseases and Innovation for Product developing countries, it focuses on improving people’s health Development in Developing Countries: TDR is an independent and giving them the chance to lift themselves out of hunger and global program of scientific collaboration that helps coordinate, extreme poverty. In the United States, it seeks to ensure that all support and influence global efforts to combat a portfolio of major people — especially those with the fewest resources — have access diseases of the poor and disadvantaged. TDR is administered by to the opportunities they need to succeed in school and life. the World Health Organization, and co-sponsored by the United Nations Children’s Fund, the United Nations Development Global Health Progress – Paul Antony, M.D., M.P.H., Executive Programme, the World Bank and the World Health Organization. Director (GHP) and Chief Medical Officer, Pharmaceutical Research and Manufacturers of America (PhRMA); Mark MANAGING EDITOR Grayson, Deputy Vice President, Communications & Jill Hronek, The Sherwood Group, Inc. Public Affairs (PhRMA); Stephen Sobhani, Senior Director, International Alliance Development (PhRMA); Margaret GRAPHIC DESIGN Wu, Senior Associate (APCO Worldwide): The Global Health Shirley Soda Opasinski, The Sherwood Group, Inc. Progress initiative brings together research-based biopharmaceutical companies and global health leaders to improve health in the AUTHORS developing world. The initiative provides a platform for research- Pam Baker based biopharmaceutical companies, governments, public health David Gilden leaders, universities, foundations, and other stakeholders to share Unmesh Kher experiences and best practices and to forge new partnerships. Ashley Mastandrea John Otrompke, J.D. David Perilstein Contributing Individuals and Organizations Uche Amizago Priya Mehta Carl Montague Samlee Plianbangchang Wendy Taylor BIO Ventures for Global Health (BVGH) 6 Case Studies for Global Health www.casestudiesforglobalhealth.org (As of October 2009) Table of Contents Methods and Acknowledgements ................................. 5 Intervention/Prevention Lesotho Apparel Industry Unites to Fight AIDS .......................116 Organizations Within the Alliance for Nevirapine Single-Dose Packs Improve Protection from Case Studies for Global Health ..................................... 6 Mother-to-Child HIV Transmission .........................................124 NATNETS Succeeds in Controlling Malaria in Tanzania With Foreword ............................................................................... 9 Effective Public, Private and Nonprofit Partners .......................130 Nontraditional Global Health Partners Team up to Fight Access Malaria in Uganda ....................................................................138 A Marriage of Divergent Interests: Partnerships in the Making of the World’s First Advance Market Commitment ...... 10 Public and Private Partnership Helps to Set the Standard of Care for Multi-Drug Resistant Tuberculosis..............................144 Vaccine Vial Monitors: Small Labels With an Immense Impact ..................................... 16 Integrating Neglected Tropical Disease Control: Comparing the Experience in Rwanda and Burundi .................150 Growing Network Extends HIV Treatment to Children in Developing Countries ............................................ 22 Integrating Neglected Tropical Disease Control: Common Themes in Niger and Zanzibar .................................158 Saving Uzbek Hearts: A Program for Best Practices in Controlling Hyperlipidemia ..... 30 Human Hookworm Vaccine Initiative Designs Rapid Deployment Strategy for Developing World .............................164 MAP’s Globetrotting Travel Pack Program
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