JPET Fast Forward. Published on March 16, 2018 as DOI: 10.1124/jpet.117.246983 This article has not been copyedited and formatted. The final version may differ from this version. JPET #246983 Molecular and behavioral pharmacological characterization of abused synthetic cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-fluoro-CUMYL-PICA Thomas F. Gamage, Charlotte E. Farquhar, Timothy W. Lefever, Julie A. Marusich, Richard C. Kevin, Iain S. McGregor, Jenny L. Wiley, and Brian F. Thomas RTI International, Research Triangle Park, NC. Downloaded from jpet.aspetjournals.org at ASPET Journals on September 24, 2021 1 JPET Fast Forward. Published on March 16, 2018 as DOI: 10.1124/jpet.117.246983 This article has not been copyedited and formatted. The final version may differ from this version. JPET #246983 Running Title: Pharmacological characterization of synthetic cannabinoids Brian F. Thomas 3040 Cornwallis Rd. Research Triangle Park, NC. 27709 919-541-6552 Downloaded from
[email protected] Number of pages: 39 jpet.aspetjournals.org Number of tables: 4 Number of figures: 5 at ASPET Journals on September 24, 2021 Number of references: 62 Abstract word count: 250 Introduction word count: 745 Discussion word count: 1495 Nonstandard abbreviations: human cannabinoid type-1 receptor, hCB1, human cannabinoid type- 2 receptor, hCB2, dimethyl sulfoxide, DMSO; bovine serum albumin, BSA; human embryonic kidney-293 cells, HEK293; Chinese hamster ovary cells, CHO; 3-Isobutyl-1-methylxanthine, IBMX; phosphate buffered saline, PBS; Section: Neuropharmacology 2 JPET Fast Forward. Published on March 16, 2018 as DOI: 10.1124/jpet.117.246983 This article has not been copyedited and formatted.