Expert Review of Proteomics

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Expert Review of Proteomics Expert Review of Proteomics Editorial Advisory Panel Overseeing the editorial content and development of Expert Review of Proteomics is an Editorial Advisory Board, composed of many of the world's leading experts in the field, drawn from both research and academia. Albala JS, UC Davis School of Medicine, CA, USA Apweiler R, European Bioinformatics Institute, Cambridge, UK Dr Rolf Apweiler studied Biology with an emphasis on Molecular Biology and Biochemistry at the University of Heidelberg, Germany and the University of Bath, UK. He worked between 1991-1994 in drug discovery at Boehringer Mannheim and has been involved in the Swiss-Prot project since 1987. He co- ordinates the Swiss-Prot knowledgebase group at the EBI since 1994, and started the TrEMBL, InterPro, Proteome analysis and CluSTr projects at the EBI. Since autumn 2001 he is also in charge of the EMBL nucleotide sequence database and started in 2002 the merge of the Swiss-Prot and TrEMBL projects with the PIR to UniProt. Dr Apweiler is heading a team of currently 100 biologists and programmers responsible for the UniProt, InterPro, Proteome analysis, CluSTr and EMBL nucleotide sequence database projects at the EBI. Rolf Apweiler's main research interests are focused on integrating heterogenous functional genomic and proteomic data resources with the main protein and nucleotide sequence databases, and automation of classification and annotation of protein sequences. Blackburn J, Cambridge University, Cambridge, UK Professor Blackburn received a doctorate and an honours degree in chemistry from the University of Oxford. Following his Doctorate, Professor Blackburn carried out post-doctoral research with Professor Fersht at the Centre for Protein Engineering in Cambridge. He then took up a Royal Society University Research Fellowship in the Biochemistry Department, University of Cambridge and was a Fellow of Fitzwilliam College, Cambridge. He has recently moved to take up a Chair in Biochemistry in the Department of Biotechnology, University of the Western Cape, Cape Town. His academic research has ranged from the synthesis of novel enzyme substrates and inhibitors, through molecular biology, protein chemistry and enzymology to the development of new display and array methodologies and the directed evolution of novel proteins. He has published extensively in highly qualified peer reviewed scientific journals and was a founder and the Chief Scientific Officer of Sense Proteomic Ltd. Following acquisition, he is now the Chief Scientist of Procognia Ltd. Borchers C, University of North Carolina, NC, USA Burchmore R, University of Glasgow, UK Dr Burchmore is Head of Proteomics at the Sir Henry Wellcome Functional Genomics Facility in the Institute of Biomedical and Life Sciences, University of Glasgow. He studied parasitology and biochemistry at the University of London, completing a PhD in 1993. This was followed by a postdoctoral fellowship at Oregon Health Sciences University, USA, and further postoctoral posts in the UK. Dr Burchmore has a long standing interest in the role of membrane proteins in cellular nutrient acquisition, and has published extensively in high quality journals. Current research interests focus on the application of proteomic technologies to membrane proteins, to elucidate the role of membrane transporters in pathogen virulence and drug resistance. Chen T, University of Southern California, CA, USA Dr Chen is an assistant professor of biological sciences, computer science and mathematics at the University of Southern California. He is an Alfred P. Sloan Fellow. He received his PhD degree in computer science from the State University of New York at Stony Brook in 1997. He was a lecturer of genetics and research fellow at Harvard University from 1997 to 2000. His research focuses on (1) the analysis of protein interactions, functions and pathways, (2) the protein identification and sequencing via HPLC-tandem mass spectrometry, and (3) the analysis of Human SNPs. Cho WC, Queen Elizabeth Hospital, Hong Kong Dr William Chi-shing Cho is a scientific officer at the Department of Clinical Oncology in Queen Elizabeth Hospital. He embarked his research work with biochemistry and Chinese medicine. After joining Queen Elizabeth Hospital, his main research interests have been focusing on local prevalent cancers such as nasopharyngeal carcinoma and lung cancer. Dr Cho’s recent work was featured at utilizing high-throughput mass spectrometry technology to discover biomarkers for cancer diagnosis, treatment prediction and prognostication. Dr Cho is an editor on several scientific journals and has published more than 60 articles covering cancer biomarkers discovery, oncoproteomics, chronic diseases’ pharmacology and Chinese medicine in publications including Clin Chem, Clin Cancer Res, Ann Oncol, J Cell Biochem, Mol Cancer, etc. He has also published books and articles on the topics of cancer encyclopedia, cancer biomarkers and proteomics methodologies with Springer and Humana Press. Godovac Zimmermann J, University College London, United Kingdom Jasminka Godovac Zimmermann is Professor at University College London, UK and Head of the Molecular Dynamics Group. She is protein chemist trained at Max-Planck Institute for Biochemistry in Martinsried, Germany. Subsequently, she worked at the Australian National University in Canberra, Australia and the University of Mainz Institute for Molecular Biotechnology, Jena, Germany. She works on functional phosphoproteomics of signal transduction by membrane receptors. Her interest is shifting to cancer proteomics and the complexity of eukaryotic proteomics. She is an author of over 100 research papers and reviews and over 100 presentations. She is also a co- founder of two biotechnology companies. Grant S, Wellcome Trust Sanger Institute, Cambridge, UK Joos T, University of Tuebingen, Germany Dr Thomas Joos is head of the biochemistry department of the NMI Natural and Medical Sciences Institute at the University of Tuebingen. The NMI is a research foundation supported by the Ministry of Commerce of the Baden- Württemberg state. The Institute is associated with the University of Tuebingen. Scientists in the areas of applied and theoretical physics, chemistry, physical chemistry, biology and biochemistry are experienced in system analysis and problem solution for industrial clients. The R&D activities at the NMI are characterised by their multidisciplinary approach. Dr Joos has been with the NMI since 1998, where he has been responsible for protein microarray technology. Prior to joining the NMI, Dr Joos did his postdoctoral research in the laboratory of Prof. Peter Hausen at the Max-Planck-Institute of Developmental Biology, Department of Cell biology, researching cell-cell and cell-matrix interaction during early embryogenesis of Xenopus laevis. Dr Joos studied Biochemistry at the University of Tuebingen. He received his Ph.D. 5 during early embroygenesis of degree in 1985 on integrin- Xenopus laevis. Kondo T, National Cancer Center Research Institute, Japan Liotta LA, George Mason University, VA, USA Dr Lance A. Liotta, M.D., Ph.D. is Chief of the Laboratory of Pathology and Chief of the Section of Tumor Invasion and Metastases in the Division of Clinical Sciences, National Cancer Institute, NIH. He is the former Deputy Director for Intramural Research, NIH. He received his M.D./ Ph.D. at Case Western Reserve University in 1976. Dr Liotta's Ph.D. is in Biomedical Engineering. Dr Liotta served his residency training in anatomic pathology at the NIH in the Laboratory of Pathology. He became Chief of the same Laboratory in 1982. Dr Liotta was one of the first scientists to investigate the process of tumor invasion and metastasis at a molecular level. Dr Liotta and colleagues in the Laboratory of Pathology invented Laser Capture Microdissection (LCM) which is commercialized and used in more than 1000 labs worldwide. LCM has been applied to make broad discoveries in genomics, functional genetics, and is now extending into tissue proteomics. In partnership with Dr Emanuel Petricoin of the FDA, Dr Liotta initiated the first joint initiative between the FDA and the NCI to develop new technology for the discovery of proteins and the profiling of signal pathways in actual human tissue. He and Dr Petricoin were the first to use "Artificial Intelligence" type learning algorithms to discover disease-associated proteomic patterns in the serum of patients that correlates with the presence of early stage ovarian and prostate cancer (Petricoin et al Lancet 2002, 359:572-577). They were the first to propose and demonstrate that the low molecular weight blood proteome is a treasure trove of diagnostic and physiologic information. The information content is contained in 1000s of clipped and modified proteins and peptides shed from every tissue and cellular compartment. Mayer B, University of Connecticut Health Center, CT, USA Morozov V, George Mason University, USA Nakamura K, Yamaguchi University School of Medicine, Japan Kazuyuki Nakamura is Professor and Chairman of Department of Biochemistry and Biomolecular Recognition, Yamaguchi University School of Medicine, Japan. He served as Director of Central Laboratory for Biomedical Research and Education from 1992 to 2000, Director of University Library of Yamaguchi University from 2001 to 2003, and now he is Associate Dean of School of Medicine. He is serving for the promotion of proteomics as HUPO and AOHUPO Council Members and Co-Chair of Human Disease Glycomics Proteome Initiative (HGPI).
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