Artificial Intelligence Outsmarts the Bomb

COLLEGEF OF oENGINEERINGr UNIVERSITYefront OF CALIFORNIA, BERKELEY fall 2011

Pay it forward. Artificial intelligence outsmarts the bomb

3 cal energy corps field report 4 tr35 for robotics pioneer 12 from bench to bedside Forefront is published twice yearly to showcase the excellence Dean’s message of Berkeley Engineering faculty, alumni and students and bring their work to life through news and research, profiles and current issues and events. Learning by doing Published by Universities often draw a sharp distinction UC Berkeley College of Engineering between pure and applied disciplines—the real Office of Marketing & Communications world, not so much. Berkeley’s approach, what 312 McLaughlin Hall #1704 Phone: 510.643.6898 I call its West Coast style of engineering, is not www.coe.berkeley.edu/news-center/ only to educate engineers as superb technolo- publications/forefront gists but also to instill in them an urgent sense of the societal implications of their work. They Karen Rhodes understand which technologies can make a executive editor real difference in the broader world. Kap Stann managing editor This issue of Forefront tells the story of our new master’s program in translational medi- Rachel Shafer associate editor cine, which is designed to accelerate the bart nagel delivery of a medical treatment or device to Abby Cohn market. In the case of our featured students, the pioneering treatment is a synthetic Shweta Doshi Julianna Fleming scaffold to encourage cardiac stem cells to form healthy vascular cells. Students spend Desiree Matloob 14 months investigating not only the technology, but also the regulatory and industrial Kate Rix framework to propel their particular advance forward as quickly as is safely possible. Robert Sanders Sarah Yang Our new college-wide professional master’s of engineering program (M.Eng.) announced contributors in the spring issue also focuses on a capstone project. Rather than writing a traditional Alissar Rayes thesis, students combine leadership skills with technical knowledge to solve pressing soci- designer etal-scale problems, in consultation with industry sponsors. As our first cohort of M.Eng. S. Shankar Sastry students took its place this fall, we were excited to see the students choose from almost dean 50 capstone projects that the faculty and industry sponsors had to offer them. They are Melissa Nidever already well on their way with these projects, with mid-project reviews in early December. assistant dean college relations “That’s the type of integrative, hands-on experience critical for graduate students step- ping into industry,” says Paul E. Jacobs, chief executive of Qualcomm and chair of the send comments and letters to: college’s advisory board. “And exactly what companies like ours are looking for.” [email protected]

This fall, we are looking at integrating more of this exciting pedagogical approach into submit your class note at: our undergraduate curriculum as well. As the Internet has totally transformed how coe.berkeley.edu/alumni/ class-notes students learn, we need to shift further away from supplying information towards more experiential and team-based learning, along with an early opportunity to practice send change of address to: innovative approaches to engineering design. [email protected] In the words of alum Cary Opel (B.S.’04 BioE), who became an R&D engineer at submit engineering gifts online at: coe.berkeley.edu/giving Genentech and is now pursuing a doctorate in chemical engineering, “I can’t over- or mail to: estimate the importance of undergraduate research. It helped me get my job, and the Berkeley Engineering Annual Fund publication I co-authored as an undergrad definitely helped me get into a top grad 208 McLaughlin Hall #1722 Berkeley, CA 94720-1722 school. It was a launching point for all of the things that I was able to do later.” Phone: 510.642.2487 I welcome your thoughts and ideas at [email protected]. © 2011 Regents of the University of California —S. SHANKAR SASTRY Dean and Roy W. Carlson Professor of Engineering Not printed at state expense. Director, Blum Center for Developing Economies

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Please recycle. This material was produced from eco-responsible material. Forefront contents h h h fall ’11

h+ Featured in this issue h h g h g h h h g 8 ARTIFICIAL INTELLIGENCE OUTSMARTS THE BOMB Machine intelligence and the science of nuke hunting. By Rachel Shafer

7 12 FOUND IN TRANSLATION Degree by degree, bioengineers learn the patient’s world. By Abby Cohn

2 Comments The gift of gait at graduation.

3 What’s new 12 The new Synthetic Biology Institute; field report from Nicaragua; training more nuclear engineers; Janet Napolitano on tour; welcoming new students; outlook for engineering grads; Abbeel awarded TR35.

6 Breakthroughs Blood lab on a chip; world’s smallest optical modulator; a better model for treating wastewater; techniques to resist radiation 4 damage; increasing solar cell efficiency and sequencing the genome 19 of preemie Baby Doe.

17–19 Alumni profiles Christopher Ategeka’s remarkable journey from Uganda to Berkeley (starting on a bike); Robert Showen’s ShotSpotter; Alice Chen’s humanized mouse liver.

20 Engineering matters Like, join, follow and watch Berkeley Engineering across social media platforms.

On the cover Computers think and reason their way through one of the United Nations’ biggest problems: how to detect clandestine nuclear weapons explosions. Read more on page 8.

cover illustration by carl wiens

17 1 2 berkeley engineering [ The spring The graduation at Walking walked across the stage at graduation to shake to graduation at stage the across walked and wheelchair his from rose eton, Whitney “Austin”exoskel- the May,of In help the with team. his Kazerooniand Homayoon professor exoskeletondesigned by mechanical engineering an with outfitted was who student Berkeley Austin Whitney,of 22-year-oldparalyzed the ; by kap stannkap by government.”the in people technology-savvy themselves.like people policy-savvy and tech-more enough,”safe are wesay to times.” enough ordinary said.not she are these “But threats. other and spamming hacking,from safe cyberspacemake to business and engineers. good few a and innovation cybersecurity for looking touruniversity national a of part as Aprilin campus to visit a during staff and students,faculty 250 some NapolitanoJanetaddressed Security Homeland U.S.of Secretary Napolitano on cyberspace security cyberspace on Napolitano “We,onthe public policy side, weknow what wedon’t know,” shesaid. “Weknow weneed for looking is department cybersecurity her that students assembled the Napolitanotold good be might area security homeland the times,in doingwere ordinary we In “what academia with Auditorium,Sibley at partner governmentmust NapolitanoSpeaking said “ ? ( Forefront ! ! . . . * ” { , ? ? ‘ told the remarkable story story remarkable the told Comments { ! ! ; ” . . . “ ‘ , } : ]

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kat wade What’s new AT BERKELEY ENGINEERING

the engineer’s advantage As the economy struggles to regain its footing, more engineers can drive innovation and growth. Yet as Intel CEO Paul Otellini, who Nicaragua serves on President Obama’s Council on Jobs and Competitiveness, notes, the number of engineers graduating from U.S. colleges and BLUEFIELDS universities has stagnated at about 120,000 a year during the last decade. “By contrast, roughly one million engineers a year graduate from universities in India and China,” Otellini says. He co-leads an education task force, an offshoot of the jobs council, which aims to yield 10,000 more

guillaume craig engineering graduates in the U.S. each year. Otellini sought out Dean Shankar Sastry, Field report from Nicaragua along with engineering deans at Purdue, Georgia Tech and Michigan, to help design David Olmos (B.S.’11 ME) spent his summer working with the nonprofit organization mentoring programs, internships and other blueEnergy in Central America as part of an internship with Cal Energy Corps, a program ways to connect engineering students to launched in spring 2011 to help develop sustainable energy and climate solutions industry employment. around the world. The ME graduate student sent this report from the field: Berkeley Engineering stands out among BLUEFIELDS, NICARAGUA—My primary objective is to design and build a 17-foot its peers as a major source of top-notch wind turbine prototype. Although blueEnergy has fabricated 12- and 14-foot turbines, engineering talent. The college awarded 958 I am responsible for creating a new prototype capable of harvesting more energy. I engineering bachelor’s degrees in 2010, already had a strong background in aerodynamics and integration of wind energy compared to Stanford’s 379. into the grid; however, these turbines are for remote villages without an electrical Of particular concern to Otellini’s task grid, and efficiency is not as much of a concern as reliability. The obstacles in this force is the poor retention of students enter- environment require me to apply engineering techniques in new ways. ing college programs in science, technology, The first step in building the blades was to scale up the dimensions of current blade engineering and mathematics (the so-called designs. Sawing and fitting the 2x4s together was like a jigsaw puzzle, trying to match STEM fields). According to the American the concavity so that they are flush without excessive strains on the epoxy resin. Society for Engineering Education, 40 per- After planing the wood and tapering the blade, remaining chunks were chipped cent of these students leave after one year. away with a machete and sanded down with a grinder. (This is where the privilege Berkeley Engineering, on the other hand, of having a bandsaw would have been useful.) Carving the pitch on the front of the consistently graduates well over 80 percent blade was more of a challenge, as the angle of the blade changes along the length, of its entering freshmen. but the change in pitch is necessary to optimize power harvesting. I have also been And the earnings outlook for engineering designing an alternative way to assemble and disassemble the blades to facilitate graduates is strong. In a report released May easier transport and repair of this larger turbine. 2011, researchers at the Georgetown Univer- I have come to realize how much of a difference a few watts of power can make in sity Center on Education and the Workforce people’s lives—by providing light for medical operations and access to refrigerated analyzed earnings based on 171 college vaccines and radio communication. I also realize that there is a great opportunity to degrees. For workers whose highest degree introduce renewable energy into the developing world because there is no existing is a bachelor’s, those in STEM fields out- f a l l 2 0 1 1 infrastructure to overcome. If a sustainable infrastructure can be implemented from perform all other occupations, with lifetime the start, these communities are likely to have a much more successful future. earnings averaging more than $3 million. Graduate degrees deliver additional payoff. See more at http://vcresearch.berkeley.edu/energy/welcome-cal-energy-corps by david olmos by karen rhodes f o r e f r o n t 3 4

berkeley engineering new what’s

elena zhukova rithms that enable robots to learn new tasks. new learn to robots enable that rithms by sarah yang sarah by at more See healthcare.” of usedtoenhance be also surgical efficiency andconsistency, improving thequality lives,”independentlivemore to people abled saysAbbeel. “Myresearchcould society.haveforcouldfar-reaching benefits learning machine them.manipulate correctly to how determine then and items target the out pick from award creationsabove, has been recognized with a prestigious his of one by caught Abbeel, Pieter pioneer Robotics new learn to robots enable that algorithms researchin his for recognized being is fall. each TR’sconferenceMIT technologies at emerging at awardsresearchwinners fields,and of range wide a from nominees of dreds hunfrom- selected 35 of age the innovatorsunderrecognizes annually Review magazine.Technology Review world’sthe innovatorsbyyoung top of 35 ics,of list 2011 the tohas named been Pieter Abbeel,known for his novel work in the field ofmachine learning in robot “Personal robots that can perform everyday chores will enable elderly and dis- and elderly enable will choreseveryday perform can “Personalthat robots of robot. a field Advancingfor the tough humans, butfor That’s enough easy computersciences,and engineering electrical Abbeel,professorof 33,assistant Technology of MassachusettsInstitute the (MIT),byPublished TechnologyReview http://www.technologyreview.com/tr35/profile.aspx?trid=1082 top youngtopinnovator roboticsexpertnamed for his work on algo on work his for - pile of laundry—identify and laundry—identify of pile crumpled a as objects—such irregular view to able be must tasks,robots those complete socks.Totowelsand ing fold- or knots surgical tying as skills such perform to robots enabled has team His surgicaland personal robotics. researchto machine-learning his applying on focused auto-rotationlandings. and maneuvers,flips as such complexaerobatic perform tohow copters have learned - heli algorithms,autonomous task.the With his onstrate dem- humans observing first by learn machines which in “apprenticeshiplearning,” conceptof the developed Ph.D.tasks.a As student,he Morerecently, has Abbeel Technology -

by rachel shafer rachel by NationalLaboratories. Sandia and Laboratory National Alamos Los Laboratory, Lawrence Livermore National National Laboratory,Berkeley Lawrence with collaborate Washingtonclosely UniversitySt.Louis.will Itin StateUniversity, University Nevada,of Las Vegasand Diego),Michigan (Berkeley, San and Davis,Irvine ablenuclear energy and technology enterprise.” sustaina ensuresolvedto be must issues,which safety,security,economic and nonproliferation all address uniquely labs,can national and sities univer participating with California,together of consortium’sprincipal investigator. “TheUniversity Jasmina Vujic,nuclear engineering professor and the base,”U.S. technology and sciencenuclear says recruitment of underrepresentedminorities. of recruitment and programs academic and departments nuclear consortium’sthe of growth support also awardwill labs. The national the on focus a with opment devel career- early and placement job in assistance receiveseminars. Finally,will students graduate and mentorships,opportunities,schools summer researchexpanded through programs ment govern-researchand toexposure extra gain will level,students field.undergraduate science the At nuclear the into students school high brightest and best the of recruitment expandaward to the use will 7) Consortium Security Nuclearand Science Mozin.like scientists lab national morecreate experts—and security nuclear with governmentthe supply help to contract tration Adminis NationalNuclear- Security Energy of million, five-yearDepartment $25 a won Berkeley area. that tivesin NationalLaboratory,- initia advancing American safeguards.Now he’s working at Lawrence Livermore nuclear in specializes engineering, nuclear in uate U.S.replicate.to Mozin,wants recentPh.D. a - grad the scientist of kind the just Mozinis Vladimir Laboratory. National Livermore Lawrence at career his ing launch is Mozin Vladimir graduate engineering nuclear Recent More like Mozin like More The consortium comprises four UC campuses UC four comprises consortium The “There is a compelling need to reinvigoratethe to need compelling a is “There To(dubbed consortium pipeline,the the grow by universities sevenled June,of In consortium a

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5 f o r e f r o n t f a l l 2 0 1 1 6 berkeley engineering MORE BREAKTHROUGHS MORE T THE ENGINEERING FOREFRONT N O R F E R O F G N I R E E N I G N E E H T AT H C R A E S E R Y E L E K R E B Breakthrou

www.coe.berkeley.edu/news-center co-authored the study.co-authoredthe engineering, nuclear Peter and Hosemann,professorof engineering, assistant nuclear reactors.nuclear and scienceMinor, Andrew materials professorof associate http://www.nature.com/nmat/journal/vaop/ncurrent/full/nmat3055.html thatare more resistant to radiation damage and to extend the lifetime existing of nique can provideniquecan relevant strength values, researchers materialsdesigntohope and safer nuclear technologies. By showing that this nanoscale testing tech- testing nanoscale this that showing technologies.Bynuclear safer and technique for testing irradiated materials that could lead to more advancedmore to lead could that materials irradiated testing fortechnique MontanuniversitaetLeoben in Austriahave developed groundbreakinga ultrafast-communications/ http://newscenter.berkeley.edu/2011/05/08/graphene-optical-modulators- seconds. of matter a in smartphone a onto movies 3-D high-definition, full-length, stream to consumers allow soon may modulators graphene-based that said Researchersallows. technology current than faster times 10 to speed—up higher much a at fiber optical by carried be then t can which form, optical into signals electrical changes modulator,that optical device a i world’sthe build smallest to graphene used successfully has researchers of team m i a Zhang, Xiang professor engineering mechanical Ledby communications. digital l d e pencillead—may bewondera material that could help break e current speed limits in sp in element same the graphite, from extracted Graphene—first pencils. your Hold the breaking Nationaland Laboratory, NationalLaboratory LosAlamos

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b a h the emission of fluorescent photons fluorescent of emission the below,promotes concept which cell solar new the to compared (a), top up cell solar conventional above,a efficiencylevels were theoretically possible. shownAs these showing byadvance this for stage the set first costs.Owen Miller, graduatea student of Yablonovitch, techniquesthat will significantly reduce manufacturing developed also They arsenide. gallium using cells of layer single a with worked Toteam the this, achieve percent. 26.4 of recordprevious the breaking percent, 28.2 of levels efficiency reaching are that voltaics Yablonovitchco-founded, have created thin-film photo- ofprimary energy. Scientists at Alta Devices, astart-up sourceexpensive least the become to poised appear that cells solar efficient more of development the YablonovitchEli to professor led sciences has puter com- and engineering electrical byresearch But fuels. convertcanenergy electricityto efficientlyas fossilas they until cloudy be will cells solar for forecast The http://arxiv.org/abs/1106.1603 Gut check Gut h h h + g h e g - h h preemies, scientists for the first time have sequenced and reconstructed the genomes of most of the of most of genomes the reconstructed and sequenced have time first the for scientists preemies, afflict that illnesses the about more learn to Hoping home. go to they’reenough healthy deemed before careintensive in months six to weeks two from anywhere spend infants premature Most courtesy the researchers the courtesy h h h n g (b).

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7 f o r e f r o n t f a l l 2 0 1 1 8 berkeley engineering intelligence outsmarts artificial the

bomb

A.I. pioneer Stuart Russell and the science of nuke hunting

BY RACHEL SHAFER | PHOTO BY NOAH BERGER ILLUSTRATIONS BY CARL WIENS

In June 2009, Stuart Russell found himself at a science and technology conference in Vienna’s royal Hofburg Palace. It was not your run-of-the-mill academic symposium, the computer science professor thought wryly: Security was tight. Hundreds of scientists, journalists and diplomats mingled beneath glittering chandeliers. In the main meeting room, an 18th-century ballroom, Beethoven once premiered his Symphony No. 8 and President Kennedy met with Premier Nikita Khrushchev in the summer of 1961. The conference topic was no less weighty. North Korea had recently detonated a nuclear weapon underground, its second nuclear test. The conference host, the United Nations (UN) Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) found the timing impeccable. The palace buzzed with purpose. The UN test ban treaty, not yet in force but ratified by 154 nations (the United States, North Korea, China, Egypt, India, Indonesia, Iran, Israel and Pakistan not among them), monitors for compliance. Its system detects and verifies signs of clandestine nuclear explosions and reports them to member states—sifting through 10 gigabytes of data per day (the rough equivalent of 50,000 emails without attachments). The recent North Korean test poured urgency into the conference: how to improve the system’s accuracy, particularly for difficult-to-detect underground tests. Russell and his graduate student Nimar Arora were at the palace to present preliminary results on a pilot project that applied artificial intelligence (A.I.) methodologies to the CTBTO’s data problem. If it showed promise, Russell’s project might significantly improve the verification process, save the UN money and potentially influence global security. It would also be the kind of success story the A.I. field craves, a field with big aspirations and even bigger hurdles. uncertain about uncertainty John McCarthy, who coined the term “artificial intelligence” in 1956, defines A.I. as “the science and engineering of making intelligent machines, especially intelligent computer programs.” But what is intelligent? In computing, most tasks today comprise an execution of orders. You tell the computer what to do in a language it understands (Java, Perl, Python, etc.), in sentences it understands (algorithms that mathematically instruct the computer how to complete a function), and it executes the order. An intelligent machine, therefore, needs to think, not just do. And it needs to think independently without human intervention and take rational action, the best 9 10 berkeley engineering told the symposium. the told systems,”intelligent towards truly moving rapidly noware Russell A.I.the fold.toresearchers returned vision “Weand news,robotics data.” of amount small good very moreIn a on learning machine Judea2010.Pearl in honoring effective install “Nowcan you another,”one torelate objects symposium a at explainedRussell don’tyouwhere howwhat’sknowcases aloneeven there, outlet universeopen with deal and objects unknown about reasonto BayesianLogic).for you(short BLOGallows“BLOG called guage lan- suchA.I. a supertool,2005,one Russell’sdeveloped had team each.By of best the exploited that computerlanguages formal create 1850s—and the in identified first conundrum difficult a decadeorso to unify first-order logic and probabilistic reasoning— forward. leapt automatedreasoning answer.likely uncertainty,Nowmanage could A.I. and scientists most the algorithms,inferred special applying by sibilities,and - pos of producedreams models world.given The a of likelihood knowledge—the inputted of amounts small with describe—even Bayes,conciselycouldThomas Bayesiannetworks mathematician 18th-century bytheorem a on 1980s. Based late the in networks Bayesian called something others,developed with conjunction professorcomputerJudeasciencePearl,UCLA until in models probability large-scale out write toexisted language ematical math- formal tools.no But statistical to researchersnext looked solveit.” approach.new a find toA.I. researchers had not will algorithms better computersorworld.faster Building real the with deal actually todefiniteness enough with and detail enough in knowledge computerenough a give never could we works,”first-orderlogic, Russell.sayswith inescapable. So is “That controltheory.and mathematics, statistics as such areaspromising moreresearchto movedtheir robotics and automatedvision as such A.I.in subfields workingMany frustrations.scientists with questions,don’t-knowssomeanswered logic abounded,along first-order while time. So the all successfullynavigate humans that logicorder can have one threeof values: unknown. or false true, own.first- its Anysentence in givenon answers deduce then could shipsbetween known objects and input that knowledge. Acomputer programmera could represent the world by mapping out relation mathematics, formal employing by first-orderlogic: using reason computersto get could they knew stalled.Scientists had progress thinking,” of ways and intelligencehuman says.stand he under to trying also was I person young a as fiction,but science representation. readingfrom “MyA.I. interestin probablycame knowledge and reasoninglearning, humans: in developed well are us.understand and speak and world world,the touchthe see also might machine not.intelligence,intelligenthuman sometimes An simulating means that plans. Sometimes develop and decisions correctmake environment,world,its understandreason,the about knowledge acquiretogoal, Russell. says needs a Itachieve action,to possible Onthe heels theof breakthrough, scientists labored over the next A.I.statistics,and with hand in hand goes oftenProbability it how and “We’reworld the of state the about always uncertain Thereare nolikely ornot-so-likely answers, degrees probability of old,butyears 1986, 30 in A.I. was Berkeley Whenjoined Russell that cognition of aspects those interestedin especially is Russell - - + SlowRes(site(a)); + SiteLocation(site(a)) ntLocation(event(a)), IASPEI-SLOW(Eve else Uniform(0,20) then null) = (event(a) Slow(a) AZSCALE(site(a))); AzRes(a) AzRes(a); + SiteLocation(site(a)) Location(event(a)), GeoAzimuth(Event else 360) Uniform(0, then null) = (event(a) Azimuth(a) TIMSCALE(site(a))); (TIMLOC(site(a)), TimeRes(a) TimeRes(a); + (site(a)),Phase(a)) (a)),SiteLocation (EventLocation(event IASPEI DURATION)else Uniform(0,TIME_ then null) = (event(a) Time(a) 0; else 1 then IsDetected(e,s) site) #Arrivals(event=e, RATE(s)]; DURATION*FALSE_ Poisson[TIME_ ~ #Arrivals(site= s) Distance(e,s); (Magnitude(e), COEFFS(s,p)] Logistic[SITE_ ~ IsDetected(e,p,s) SiteLocation(s)); (EventLocation(e), graphicalDistance Distance(e,s) MIN_MAG; + Exponential(log(10)) Magnitude(e) Distribution(); UniformEarth Else Distribution() arthQuake then IsEarthQuake(e) If EventLocation(e) Bernoulli(.999); IsEarthQuake(e) DURATION*EVENT_RATE]; Poisson[TIME_ ~ SeismicEvents # = If If = ~ If If ~ If ~ ~ Laplace(0, Laplace(0, ~ ~ If If ~ Laplace ~ ~ = Geo = ~ ~ reasoning learning intelligence knowledge short presentation. short a during model the afternoon,demonstrated Russell That long. lunchhour writing probabilitya model inBLOG. It was half-pagea geophysicsinvolved.his and spent he seismology Then the about world. unknown an on meaning confer waveform signals—and seismic case this data—in rawfrom locations their and eventsInfer for: looking been had itsrapidly growing library data. of This was just the project Russell CTBTOexploitthe help tohow know might Russell thought and CTBTOinitiatives,on working Livermore NationalLaboratory Lawrence at scientists knew Rector seismology. applied and geophysicsexploration in specializes professorwho engineering environmentalRector,Jamesand friend civil long-time Berkeley a fromheard 2008,he of fall the in daytool. One the out test would problems.worldmust solve real must Artificial “get”real. being for Yet,for however much he’s a professor’s professor, in afield known youto know A.I.’scontext, and most important, its open questions. Google’sdirector research. of Whenyou talkto him, Russell wants Intelligence: AModern Approach textbook, leading field’s the coauthored He is. also he researchlongtimeteacher—whicha pioneer—which is—butof he a of perspective A.I.,discusses the it’sfrom not usually he When wit. dry a with conversation lightens and tie the without jackets thoughtful,A cerebral Britishmanawith accent, Russell favors suit intelligence nuclear the project might, just might, influence geopolitics.influencemight, U.S. just might, project “The the CTBTO’sat unit in CentreVienna. Data International proven,”and integration software the of Bras, head LeRonansays nexttwotheyearsso,within or onceit’s sufficiently adapted, tested us for upgrade operational major a to lead will work this that chance good very enthusiastic.CTBTOa scientists has is “There three. That of factor a further,byevents model missed reducing system.existing CTBTO’s the than events seismic infer better could reasoning, pairdemonstrated thattheir model, itswith A.I.-drivenautomated CTBTO’sconferenceyear, that technology and science the annual the HofburgPalaceCTBTO the during data.using Then,at model fiveminutes.”actually.than right, less be tookcould It I don’ttist,youyou’re what know about.’talking realized they Then remembers.thought, they up,think ‘Shut computer“I youscien- large. writ evidence—intelligence the givenexplanation able prob- most the determine and them between relationships the and empoweringsmalla computer program tolook at groupssignals of by head its on that all dumped Russell explosion. nuclear or earthquake an by caused be to size sufficient of is it if determine to separately signal each analyze to methodology bottom-up cated,multimillion-dollar software system that uses awell-known, sophisti a and CTBTOanalysts humandata.employs The seismic For more than 100 years, seismologists have been analyzing have been years, seismologists 100 than moreFor more learn to March2009 in CTBTO meeting a attendedRussell that project a for BLOG,hunting developingAfter was Russell Russell is happy to see A.I. demonstrating its chops and hopes and chops its A.I. see demonstrating to happy is Russell Now,later,yearstwo haveAroraand improvedRussell the the Berkeley,refinedstudentArora at graduate Back and Russell shocked,”Russell little a and surprised were they “Initially, , Russell is a firm believer in the real world.real the A.I. in believer firm a there,is Russellout ,with Peter Norvig (Ph.D. ’86 EECS), Artificial Artificial

will never close.”never will intelligence artificial and human between process. gap the The in we’resmarter, them tool.If we’remaking then smarter becoming a computersas alwaysuse happen. Humans towill going never antiquated,says,right?’” he laughing.yourself making it’s“But superhuman,not?”whysays.the create he can ones. webiological “If of insteadchildren machine through death code,cheating genetic of insteadcomputer codeourselvesthrough extending mortality,of way against a fight ancient an simply is intelligencemachine for quest course,our presentbelieves its on another.A.I. modern set Judea professorPearl,who UCLA the way,it.”that see In I know goal? A.I. when I’ll ligent,”says.its achievehe and moveon recover?it it “CanCan intel- seem it makes what is error to reacts machine a me,how failure.test: another in intelligent.believescrownedRussell “To computer,and humancan’t between computeris distinguish the judge the If curtain. a behind hidden computer both one and human one participants, conversestwo judgetest. humanwith A Turingthe is intelligencemachine measure to ways famous most intelligence.human on rely frombeingSwissthe problem-solving, Army knifeof stilltheyand Yetcomputershoweverhaveintelligentbecome,for they’re far Microsoft’srecommendationsand shopping technology.Kinect Google’sin algorithms,daysearch Amazon.com’s every it personal smart. Yougetting is intelligence What’sartificial that see is certain immortality for fight our judgments.”educated better make can we so forward envelope the moving is Stuart tionyou have, themore likely youisit canmake decision. theright ratify,to U.S.nations says,otherbut, she or - informa more “The the encourage will model won’tproject.the She whether predict the LivermoreNationalon RussellLaboratory, with collaborates U.S.the ratify.”for toeasier it make can we maybe events,”verify to Russell.excuse,saysremove that can then we “If it’sthat hardclaims treaty,too it hasn’tthe because part,ratified in nations, BLOG and the task of hunting nukes.hunting of task the nations,and BLOG Terminator.”and robots with works—thanknow we wehave much better ways destroying of ourselves—with technology socks,”folding at good it’s pretty getting Russell.says now, “Right though soon,even anytime world overthe taking it about worried socks,wouldn’tyou too of be pair a fold to trying developed has away,decade predicts.Russell aren’tbehaviors their ensureit’sunexpected. Buta than more tosystems intelligent designing as problemssuch engineering basic more with grapple as well as conundrumsconfront ethical haveto will matures.acknowledge,Scientists A.I.as inevitably Therewillcome timea for closer introspection, Russell and others Nimaragrees.Arora alwaysjoke,“My friends ‘You’re basically is thing,it’s good whether thing;a Recognizingone A.I. is the of One achieved? been has goal the when know weHow do LawrenceSheila at Vaidya, programs defense of director deputy At that, Russell returns to his computer and the world of rogue of world the computerand his to that,Atreturns Russell 4] page on story Pieter[see Abbeel robot the see couldyou “If F

11 f o r e f r o n t f a l l 2 0 1 1 12

Found in translation in Found Degree by degree,bioengineersby Degree patient’slearnthe world R E G R E B H A O N Y B S O T O H P | N H O C Y B B A Y B world,”says. he real the in application to lab researcha frompathway get to whole the understand to needs revolution,biotechscientist the processes.business and we’re clinical, regulatory a about “If in manager, learn lab toHall wanted Stanley he a as working and Intime, program leaders want to grow the number ofstudents to 30. experience. industry with participants and student international student,an medical a includescontingent new applicants,the 200 nearly from Selected training. yearlong their recentlybegan summer.this students number 14 equal An of class first its ated running. and up effort the get Healthcare,”to million November$1.5 donatedin 2009.thenHe UCSFconference, “TranslatingTechnology Cost-Effectiveinto proposedthe translational program at a Berkeley Engineering- “better,faster, cheaper”development. product toapproachGrove Siliconadopt toValley’s medicine Grove,sayschallenged has who BerkeleyandUCSF campuses embraced andadvanced theconcept. UC the on Faculty (Ph.D.’63ChemE). Grove Andy visionary technology and executive chief Corporation Intel former of regenerativemedicine. of field inventorthe an in become to hopes itself,”processin another is researchout get to Dashti,sayswho needs. medical real address technologies new that ensure journey—and bench-to-bedside the hasten to encouraged are creativity and care. Collaboration patient in advances of delivery actual the and discovery scientific between complexsteps the in clinicians and engineers,scientists young trains venture pioneering This Sciences. Therapeutic and Bioengineering of UCSF’s and Department Bioengineering of Berkeley’sby launchedDepartment jointly program degree (MTM) medicine translational of master new a in participants therapies. and devices drugs, new of rollout the speed tohow learning year(M.S.’11Chitters past and the spent BioE) (B.S.’09,innovation, Dashti medical such costs—of M.S.’11 BioE) stretchesyears. 13 drug’sdetection inthe lab to its formal approval a from span average time school. The grade in 21-year-old still wereRamyaChitters and 23-year-old Dashti Derek when local pharmacy’s shelves isn’t allthat new. hebrand-new drug arriving on your Dashtijumped at the chance to enroll. Trained in bioengineering - gradu unveiledand Augustin was 2010 program degree joint A “Whenyou have problem,a look to technology for solution,”a Onethe of first programs its of kind, the MTM is the brainchild research.on muchUnderstanding so how focused are “Scientists inaugural the amongwere bioengineers minted freshlytwo The soaring pace—and sluggish the concernabout growing Amid Chances are, it was discoveredwas are,back Chancesit

capitalists and others share their expertise and advice. and expertise their share others and capitalists entrepreneurship.and executives,Physicians, industry venture andclinical trials to cost-effectiveness analysis, patent applications Theytake classes intopics ranging from medical device innovation departments. UCSF of number a and Business of School Haas MTM’sdirector.the co-faculty and medicine,” bioengineering professorof Berkeley Li,a Song says and engineering of interface this at work can who generation new a technology.train medical is in do can we what “Hopefully innovators.and leaders industry program’sthe in development.partner close a been has Engineering, Berkeley (CTSI).Institutewith ScienceCTSI, along Translationaland Clinical the of director and UCSF researchat of accordingto S. Claiborne “Clay”Johnston, associate vice chancellor increased,havenot drugs new 2005,approvalstoof 1995 from researchfunds federal of doubling inflation-adjusted an Despite use,”patient direct says. she into turned is everything not butamazing, something on working products.marketplacebecome ideas promising how “Everyoneis clue no had she realized she when undergraduate engineering They evaluated the need for treatment, looked at competing competing at looked treatment, for need the evaluated They exploredtheir project from avariety clinical of and financial angles. stages,promising,”quite looks “it Dashti. says early the in Unitedstill the States. Though in year each performed transplants heart 1,800 the to alternative accessible more and cells. healthyvascular intogrow to them promptto a provide and “pro-survival”place in cellsenvironment stemkeep tointended is scaffold scaffold. That synthetic a via tissue cardiac patient’sa into damaged Yeghiazarians,cells the inject to hopes collaborator clinical YeremUCSF includesteam, which plinary rejuvenate.to potential Eventually,their and cells interdiscithe - stem cardiac Healy,Kevinof growth monitoredthe students the chair department professorand bioengineering of lab Hall Stanley the Joininghearts. diseased seriously regenerating conceptfor a care. patient in advances new for landscape complexregulatory the and developmentbusiness research,basic to exercisethem hands-on exposes ment. The navigatethetranslational pathfor actualan device, drugortreat to knowledge their Workingapply studentsteams, the small in a in together“capstone”comes Everything researchproject. do then learn, Students divide their time between Berkeley Engineering, the Engineering, Berkeley between time their divide Students MBA an to experience educational the likendirectorsProgram become to preparegraduates better tointended is MTM The problem.widespread fact,a researchis,in translating Effectively bio- Diego San UC a researchas basic conducting was Chitters Beyond that cutting-edge bench research, Dashti and Chittersresearch, and bench Dashti cutting-edge that Beyond successful, If theconcept could lead tofar acheaper, less invasive Dashtiand Chitters devoted months to their high-stakes project—

13 f o r e f r o n t f a l l 2 0 1 1 14 berkeley engineering $1 billion,accordingCollins. to$1 than more is market to drug single a bring toaveragecost the failurerate for drugs under development exceeds 95percent, and conditions. and diseases methodsand technologies” to create better responses to human innovative of generation the to “catalyze be would mission NationalforCenterAdvancing Translationala of Sciences.Its pathway, medical the establishmentin the recentlyproposed he rates”failure high and costs timelines, steep long of frustrations Health. Citing National of Institutestriple the “the of director problem.”solvethe actually expensivebut most the aren’tthat technology developing about think to able be might up,”says.she Without compromisingsafety, weways “thereare director. co-faculty MTM and sciences peutic going“Costskeep - thera (Ph.D.’98and bioengineering professorof UCSF BioE),a safety,advocatessay. process.”the haveacceleratedwould there’sit,started, I got about questionI no me,”for eye-openerbefore program MTM an recalls. had he I “If issues. an regulatory definitelyother FDA was “Itonand himself educating researchcareer, while his devices medical Roydeveloped in curve. Earlier field’s learning the steep with experience personal startup. a into technology the spinning of possibility the exploring professorShuvoRoy,associate native.UCSF by Led is team the get,”can we far how seeing and LosAngeles-area forward the says labor.term now, technology “Right the pushing I’minterestedin pre- of onset the predicting of capable “smart”diaphragm cervical researcher.a a developto as helping he,on too,is staying Chung is Chung,23. me,”formatch master’swas perfect a muchtraining “pretty says business,the and medicine clinical engineering, combiningBy impacting.” be to wanted I setting clinical the from detached bioengineer,young a as too because felt program “I MTM the physician-scientist.a become to program Berkeley.M.D./Ph.D.Eventually,joint a in enroll tolike would he California’sSanta Clarita Valley,continues to pursue his research at businessman,”says. Dashti a lawyerpatentor a to go you when happens what understand can weway “We’re a in educated but training by bioengineers pathways.”that regulatory found “there’sof plethora a property, intellectual protectto patents Dashti filing ceduresfor technology.and practice medical of crossroads the interestedin standallthe different aspects it,” of says Chitters, Cupertinoa native underyou if faster lot a analysis.goes cost it a think performed “I approaches,planned aclinical trial, prepared abusiness proposal and Along with the typical 13-year timeline for drug approval, drug the for timeline 13-year typical the with Along Joiningin the call for more translational efforts is Francis Collins, Desai Tejal says inefficiencies,” many so are there think “I Translationalmedicine doesn’t translate into skimping on product innovation,has device medical Roy,in class a teaches also who that project capstone his by inspired so was Dashti,ChungLike (B.S.’10,Chung Philip Fellowclassmate M.S.’11 enteredBioE) Southern in up grew who July, Dashti, in graduating Since terrain.uneven that of roadmap a offers program MTM The proFDA- the requirements and of complexities the studying In

their unmet clinical challenges.clinical unmet their “Whyinventyouwouldsomething physiciansand toAnti-Medical School, called students introduces backers.course, requiredprovocativelyMTM translational toA accordingcollaborating, and communicating of job better a do big.” very be wouldproducts, that and technology to ideas translating in efficient very says. be could someone “If inventions. actual into turned everare there,” “There’s gap a he intolostcreativity. Henotes thatonlysmall percentagea patents of Forinnovation to be more successful, clinicians and scientists must life new breathe will efforts translational that Berkeley’shopes Li to get research from a lab to application in the real world.” real the in application to lab a from research get to pathway whole the understand to needs scientist the “If we’re in a biotech revolution, biotech a in we’re “If tive heart failure. heart tive conges of costs financial and human devastating the address day one could Healy,Kevin professor and chair department neering bioengi of lab Hall Stanley the in housed effort, tive collabora The disease. heart serious for treatment invasive minimally and inexpensive an seeking project research novel a of part as cells stem cardiac of growth the study BioE) (M.S.’11 Chitters Ramya and BioE) M.S.’11 (B.S.’09, Dashti Derek (below) CULTUREA INNOVATION:OF - - -

BEYOND THE BENCHTOP: (left) Along with their scientific explorations, Dashti and Chitters spent the past year learning how to navigate a concept for regenerating damaged cardiac tissue through a variety of clinical and regulatory hurdles. The master of translational medicine (MTM) program jointly launched by UC Berkeley and UCSF introduces young innovators like Dashti and Chitters to the pathway linking initial research discovery to the actual delivery of new medical technology. In this way, the MTM program aims to accelerate the development of drugs, healthcare devices and therapies.

“If we’re in a biotech revolution, the scientist needs to understand the whole pathway to get research from a lab to application in the real world.”

not knowing what the needs are?” asks Marc Shuman, clinical Though the program he spurred is in its infancy, Grove director of the California Institute for Quantitative Biosciences, likes the progress he has seen. a UCSF professor and the class’s originator. “It’s that frequent, The MTM program, he says, is “a starting point to establish mutual exchange that’s absolutely critical.” that teams of interdisciplinary people can address increasingly Chung shadowed doctors at an OB/GYN clinic affiliated with complex problems that require interdisciplinary approaches.” UCSF to figure out how to better design the obstetric device his Displaying the same restless drive and passion that made team is developing. “Our team in the lab is all engineers,” he says. him a digital-age legend, Grove is a fierce champion of better, “It’s very difficult to understand what happens in a clinical setting.” faster, cheaper medicine.

As it embarks on its second year, the MTM program continues “I’d like to see medicine working like the cell phone industry,” f a l l 2 0 1 1

to evolve. The program’s first graduates received a master of science he says. “You don’t sit around being evaluated for 14 years for degree in bioengineering with an emphasis in translational medicine. the next available iPhone, Android or whatever. The technology In the works is a proposal to designate a new professional degree, flows and it’s twice as good and half as expensive. Every cell a master of translational medicine, which would be jointly awarded phone engineer is translational.” F by Berkeley and UCSF. f o r e f r o n t 15 16 berkeley engineering student withtheLaserInter iscurrently aPh.D. EECS) ELIZABETH HAUSLER ELIZABETH afford tofly!”hewrites. real jobsothatIcanactually out ofgrad schoolandintoa 152. “Now Ijusthave toget mond, Louisiana, inaCessna license, flyingoutofHam- earned hisprivate pilot’s thathejust excited toreport Observatory project. Heis ferometer Gravitational-wave FRICKE TOBIN CHERRY CHRISTOPHER company intheworld. named atopstudent-run ate studentatHarvard was co-founded asagradu- thatshe when thestart-up New York Stock Exchange, ety onthebalconyof Award from theKairos Soci- accepted the Technology country. InFebruary, she preneurship across the promote high-growth entre- a nationalcampaignto tive America,” for“Startup new sciencepolicyinitia- ogy Policy. Herfocusisa of Scienceand Technol - as anassociateintheOffice named by the White House (B.S.’05 BioE)wasrecently BOWERMAN HEATHER 2000 two-wheelers inChina. increased usageofelectric includes research onthe Award forhiswork,which Early Career Development ence Foundation’s Faculty awarded theNationalSci- nessee, Knoxville. Hewas at theUniversity of Ten- environmental engineering tant professor ofciviland isanassis- (Ph.D.’07 CEE) developing world. resistant housinginthe to establishearthquake- tech reconstruction method Change, shepromotes alow- CEO andfounderofBuild Award forSustainability. The $100,000 Lemelson-MIT front, recently wonthe2011 spring 2009issueofFore- who wasprofiled inthe (M.S.’98, Ph.D.’02CEE), (B.S.’03 s

Class notes Class Keep in touch by mailing your news and photos to to photos and news your mailing by touch in Keep coe.berkeley.edu/alumni/class-notes to go Or 94720-1704. CA Berkeley, #1704, Hall McLaughlin 312 Engineering, of College

courtesy misha leybovich radios. devices andenergy efficient multimedia design, portable wireless microsensor system mixed-signal circuit design, on micro-power digitaland faculty in1994,withafocus sciences. HejoinedtheMIT engineering andcomputer ofelectrical department named headofMIT’s Massachusetts, hasbeen Belmont, of EECS) (B.S.’89, M.S.’90,Ph.D.’94 watch Calfootball.” having togetupat3am necting with friends and not am looking forward to recon 30 countries.Hewrites,“I ment; and visiting more than national wrestling tourna- competing inMongolia’s inUzbekistan; birthplace pilgrimage tohisfather’s treacherous mountain;a ing soloonChina’s most midwinter nocturnalhik- of histimeabroad include ment manager. Highlights he isnow ajuniorengage- McKinsey & Company, where a year inShanghaiwith returns toAtlantaafter ES) iSchool there. ate teachingprofessor atthe and waspromoted toassoci- neering atDrexel University his Ph.D.inbiomedicalengi- Pennsylvania, completed Philadelphia, of ME) ANANTHA CHANDRAKASAN ANANTHA BOOKER GLENN 1990 LEYBOVICH MISHA Misha Leybovich Misha s (M.S.’90

(B.S.’05

Systems. for BiomedicalEngineering and director oftheCenter engineering andthefounder a professor ofmechanical lina, Charlotte.Sheisalso CaroUniversity- ofNorth lege ofEngineeringatthe named deanoftheCol- Carolina, hasbeen North ofMatthews, Ph.D.’93 ME) MARIE DES JARDINS DES MARIE COGER ROBIN CHATTERJEE SANDEEP of UMBC’s facultyaffairs faculty fellow andthechair asanhonors I alsoserve women tofullprofessors. more goals istosupport andoneofmy at UMBC, areas full professor inSTEM only the11thwomannamed since 2001.Shewrites,“Iam has beenafacultymember Baltimore County, where she the University ofMaryland, moted tofullprofessor at Maryland, wasrecently pro- (Ph.D.’92 CS)ofFulton, mobile transactions. transaction software for produces remote financial Systems, acompanythat founder ofSourceTrace Forum. Heisalsotheco- by the World Economic Young Global Leader for 2011 California, wasnameda (B.S.’95 EECS) of Foster City, and click on on click and (M.S.’90, Forefront “Submit a new class note.” class new a “Submit

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georgia tech PHU QUANG PHILLIPS HUYNH PHILLIPS QUANG PHU edu.” area, [email protected]. you’re goingtobeintheD.C. drop mealine,especiallyif Heather atHarvard. Please Caroline inhighschool,and two daughtersare thriving— committee. Meanwhile,my JASON MIKAMI JASON MAY GARY school. and computerengineering well aschairoftheelectrical has workedasaprofessor as joined the faculty in 1991 and Institute of Technology. He neering attheGeorgia dean oftheCollegeEngi- Georgia, hasbecomethe ofAtlanta, Ph.D.’91 EECS) September 2011 profiled in B.S.’98 EECS), East AsianLanguages, competition. San Francisco Chronicle wine wine medal at the prestigious Vineyards, whichearneda winery, Mikami artisan an of founder and owner the also is He SugarSync. firm computing cloud the at operations of dent was promoted tovicepresi- program managercertificate. obtained aStanford certified worked atMobiTVandhad manager. Previously, he senior engineeringprogram Global BusinessUnitasa recently joinedHP-Palm of UnionCity, California, (B.S.’98 EECS) (B.S.’98EECS) (M.S.’88, (B.A.’92 Innovations

Research CenteratPurdue. the NSF Cooling Technologies engineering anddirector of professor ofmechanical aswell asa Department, Fellow attheU.S.State rently aJeffersonScience for engagement.Heiscur first associatevicepresident named Purdue University’s Lafayette, Indiana, has been of (Ph.D’89 ME) West VERONICA J. SANTOS J. VERONICA JACKSON NICKERSON JACKSON LOKKEN T. ROALD GARIMELLA SURESH 1980 ruption inengineering and training filmtoaddress cor executive producer ofa projects. Hewasalsoan tionships ininternational Inc. tohelpfirmsbuildrela- Transnational Associates International andhasstarted as president ofCH2MHill JR. (B.S.’65, M.S.’66CE)retired SCHIRMER HOWARD Upstream Research Company. is assignedtoExxonMobil and engineer forExxonMobil been appointed chief offshore ture) ofHouston, Texas, has Ph.D.’80NavalME, Architec- versity inSt. Louis. School at Washington Uni- strategy attheOlin Business fessor oforganization and Press, 2010).Heisapro- World (Brookings Institute ing Changeina Web 2.1 Missouri, haswrittenLead - istration) ofSt. Louis, Ph.D.’97 BusinessAdmin- MBA’90, (M.S.’86 ME, Award. Early Career Development ence Foundation’s Faculty selected fortheNationalSci- University. Shewasrecently engineering atArizona State professor ofmechanical Arizona, isanassistant of (B.S.’99 ME) Tempe, s (B.S.’75

- -

courtesy christopher ategeka conditions. living improved and work education, to access able afford and energy-efficient provides particular, in bicycle, poverty. The global ease to motivation own his and others of support the luck, by guided was stage Commencement 2011 the to Uganda rural from Ategeka’s journey Christopher BIKE: THE ABOUT ALL IT’S The long road to Berkeley to road long The - ride to school was only 30 minutes. I could make it makeminutes.could 30 I only was school to ride month. a $25 with him providedOakland, California, who in sponsor a with Uganda.in agencyThrough YES,matched Ategeka was American-run an (YES), Services Encouragement homework. do and siblings his feed would dark,he the in school.home tobarefoot returningwalked After moving.” Einstein. balanced,staykeephaveyoutotoorder “In bicycle,”a like is “Life said,Albert quoting man the bicycle. his on ride a him offered and stopped stranger a when home road long the died,parentswalking Ategeka his was after long Notapart. miles seven located village his and school another.relativeto one hard, with was Life of care the from shifting of period turbulent a was followed old.yearsseven What was he time the by toAIDS ents played a pivotal role along the way: the bicycle. the way: the along pivotalrole playeda tool,however,outlook.positiveOne a and luck of help the with Berkeley.hardship and heartbreak enduredHe to Ugandanvillage rural a from journey formidable May,ChristopherAtegeka (B.S.’11 recountedhis ME) Engineering’sBerkeley Commencementin at Speaking “I saw how powerful a bike can be,”bikecan a powerfulsawhow “I Ategeka says. “My bicycle.purchases?A first his of One Eventually,contact Youthhe suggested friend family a going,”things of balancekeepthis to had “I recalls. he day,Everyheart.words to those Ategekatook he words:memorable some with him left stranger The The eldest of six siblings, Ategeka had lost both par both siblings,lost six Ategeka had of eldest The life,”mychangedbike a “Getting says. he - by kate rix kate by at more See up.”went grades my and studying, time my spent siblings.I myfor food find to dark before home love.there.”out That’sis what and luck is therelove. think no I is there say people says.there,he outand luck no “Peopleis theresay world,”the in suffering kids manyother so are “There back.give and started journey his where to return to engineering. mechanical in program doctoral a begin them. afford can who those to bikes sell to Eventually,hopes he Uganda.in task small organization—no his for status andHIV/AIDS patients. He has already secured nonprofit residents—includingschoolchildren, healthcare workers village needy tobicycles the distribute tocles. aims He repairconventionalrefurbishand motorizedbicy and Ugandansbuild, help BikesUganda, to projectCA a projects. special for money seed BaccalaureateprovidesPrize, which Berkeleyseniors awarded the 2011 Judith Lee Stronach five of one was Ategeka engineering, mechanical B.S.in his 2009. Earning in Berkeley to transferred and honors highest with College,graduated Laney in Oakland.enrolledHe livein come to him for paid After his graduation from high school, his sponsor school,his high from graduation his After For Ategeka, CA Bikes Uganda is an opportunity Foropportunity Ategeka, an BikesUgandais CA to 2012 spring in Berkeley to return to plans He launch to summer the Ugandatoin Ategekareturned www.cabikesuganda.com alumni update alumni

doug cody/bay area event photography 17 f o r e f r o n t f a l l 2 0 1 1 alumni update

construction, the center- piece of a program to assist the poor and underprivi- leged around the world. Alert! Shots fired In 1992, the city of East Palo Alto on the San Francisco experienced 47 homicides. In 2010, that number fell to 1970s Peninsula logged the highest homicide rate per capita 21. Lieutenant David Harris of the Richmond Police in the nation. Robert Showen (B.S.’65 EECS), a specialist Department attributes the drop to both ShotSpotter FRANCOIS FOURNIER (M.S.’71 CE) of Neuilly Sur in acoustics and radio wave propagation, worked just and better community policing. “It’s amazing technol- Seine, France, has been two miles away, and he wondered: What if technology ogy that has become a normal part of our day-to-day “retired” since 2006 from the could locate gunfire and tell police where it came from? patrol deployment,” he says. “It’s making a remarkable steel industry, and today serves on the board of direc- Today, Showen’s ShotSpotter systems are located in difference.” tors for steel companies in 70 sites around the world, including East Palo Alto. by rachel shafer Morocco, New Caledonia and “We’re giving the police a tool to help reduce gun France. crime,” Showen says. “We’re proud of what we’re doing.” GRANT ERIC HOAG (B.S.’79 When a gun is fired, it produces impulsive sound CE, MBA’82) of Irvine, waves, a short blast of energy that creates the pop we hear. A network of acoustic ShotSpotter sensors, installed throughout urban communities, listens for the unique sound. When one is detected by multiple sensors, the system’s software calculates its point of origin using differences in arrival time at the sensors, explains Showen. California, is a registered civil engineer with Camp Each sensor also records an audio clip of the event. Dresser & McKee (CDM). He The system generates “shots fired” alerts that are sent also practiced financial plan- to police dispatchers, 9-1-1 operators and sometimes ning for cities and municipal utilities over the last 25 years officers in the field. A specialized computer display and is otherwise “living the marks the location on a map with a red dot, indicates good life.” the time and number of rounds fired and includes the GLEN LANGSTAFF (B.S.’77 audio clip for playback. Officers use all the information rachel shafer ME) of Fairfield, California, FIRST RESPONDER: In the control room of his company’s to decide their response. The data are logged for use in has returned to campus after headquarters, ShotSpotter co-founder Robert Showen a 34-year hiatus to work at forensic investigations and trend analysis. explains how potential gunshot incidents are displayed and Lawrence Berkeley National Police credit the technology with reducing gunfire, logged. Showen, partially retired, is still writing patents and Lab. Previously, he had worked in the medical, catching suspects and saving lives. In 2009, the year it working on improvements to the system’s acoustic signal electronics, military vehicle installed ShotSpotter, the city of Richmond, California, processing. and steel industries, and had run his own equipment design and marketing company in the food industry. “It’s good to be back in the in cycling and woodworking. served in the Navy on diesel middle of some of the best He worked in engineering and nuclear submarines for science in the world, not to s 1960s sales of commercial air con- five years, then served an 1950 mention the eclectic environ- ditioning systems and also additional 12 years in naval AMIRAM M. EISENSTEIN ment that Berkeley offers,” ROBERT A. SHULTZ (B.S.’65 in management during his intelligence. He retired from (B.S.’51 EE) of Sebastopol, he writes. ME) of Los Gatos, California, retired at the end of 2005 35-year career with Trane. the Navy with the rank of California, retired in 1989 and is now actively involved Prior to joining Trane, he commander in 1984. from the aerospace industry

LARRY A. ESVELT (M.S.’64, Ph.D. ’71 CE) of Education and volunteered for the college’s Annual in memoriam Spokane, Washington, died in April at age 72. As Fund. KENNETH BARNHART (B.S.’47, M.S.’49, Ph.D.’55 the owner of Esvelt Environmental Engineering, he BRODERICK P. HASKELL (B.S.’50, M.S.’51 CE), of ME) of Concord, California, died in March. He was designed numerous wastewater treatment facili- Berkeley, died in February. a mechanical engineering professor at California ties throughout the Northwest. State University, Fresno. EUGENE HERSON (B.S.’65, M.S.’66 CE), founding RICHARD E. HALL (B.S.’38 CE), of Berkeley, died chair of the Civil and Environmental Engineering PEDRO DE ALBA (M.S.’69, Ph.D.’75 CE) of Dover, on August 24, four days short of Advisory Council in 2006, died in June. The San New Hampshire, died in February his 94th birthday. A WWII Navy Francisco resident was CEO of EMCON Associates, at age 71. He was a civil engineer- Seabees veteran, Hall joined an environmental engineering company. In ing professor at the University of Underground Construction in 1946 2003, he received the college’s Distinguished New Hampshire. His professional and retired in 1992 as its chairman Engineering Alumni Award for his engineering interests were in experimental of the board. He received the col- achievements and public service. techniques for measuring the lege’s Distinguished Engineering dynamic response of soils, espe- Alumni Award in 1987. A loyal graduate whose TIMOTHY T. HUANG (Ph.D.’99 CS) of Middlebury, cially the residual strength of liquefied sand. He blood “ran blue and gold,” according to his obituary, Vermont, died in June. He was an associate profes- was also co-editor and founder of the earthquake Hall established the Hall Fund for Undergraduate sor of computer science at Middlebury College. berkeley engineeringengineering journal Sismodinámica. 18 gence gathering. gence intelli - for radars imaging to addition in radars aircraft of production and development the led he where years, 35 for Company Aircraft Hughes at engineer aerospace an as worked veteran,he Navy A 87. age at February in died California, Creek, EVERETT G. NEUMILLER G. EVERETT M BRUCE intelligence. artificial on focused research His Award.Development Career Early Foundation’sScience National receivedthe Faculty he 1997, in faculty the joining after long Not he worked for Bell Labs for 48 years. 48 for Labs Bell for worked he veteran,Army Jersey,An New April. Hills, in died a city engineer. the 1950s, as well in Arcata as he worked in Afghanistan in sional consulting. Previously, where he still does occa and geology firm since 1965, engineering, land surveying worked as the owner of a civil CE) of Arcata, California, has ELMAN F. NIELSEN F. ELMAN MEYER W. ROBERT FRY W. HARRY 1940 SWEET B. WALTER LINDHOLM R. ROGER property. radios and landscaping his is now busy restoring antique (TRW and Hughes Aircraft) and agricultural drainage. tion andreuse, aswell as supply, treatment, reclama- researched projects onwater aged, investigated and Water Resources, heman- of California Department a seniorcivilengineerforthe California, retired in1987.As (B.S.’50 CE)ofSacramento, expire whenheturns98. California driver’s licensewill Long Beach for21years. His who workedfortheCityof and mechanicalengineer battalion. Heisaretired civil ofaNavyconstruction part in served World War as II ME) of Long Beach, California, 99 in November. What asweet life.” He turns taste ofmyveggies. Wow! smell ofmyflowers andthe am enjoying thebeautyand away in2008.Hewrites,“I with hiswife,whopassed five daughtersandason from PG&E in 1977. He raised of Fresno, California,retired CE) ofOrinda,California, c VEY VEY (B.S.’40 EE) (B.S.’40EE) (B.S.’48, M.S.’50 EE) of Walnut EE) M.S.’50 (B.S.’48, s (B.S.’47 (B.S.’47 (B.S.’50

- (B.S.’35 EE) of Short Short of EE) (B.S.’35

public radio station. classical musicatSantaFe’s and produces aprogram of State Library fortheBlind volunteers at the New Mexico Alamos Lab.” Now retired, he graduate studentsattheLos mer employment program for for makingknown thesum- to Professor Lester Reukema National Laboratory. Thanks mentation attheLos Alamos nuclear testingandinstru- in until 1988,Iparticipated writes, “From graduation ofSantaFe, NewMexico, EE) ROBERT L. WHITE L. ROBERT PECK C. ROBERT wildlife biology. uated from ChicoState in while athird daughtergrad- and landscapearchitecture, from Berkeleyinarchitecture his daughtersgraduated residential projects. Two of work onmajorwineriesand marine terminal,aswell as Canada’s NewBrunswick Larkspur’s ferry terminal and version tocontainerization, ofOakland’sthe Port con- major assignmentsincluded his own practice. Some of his ways, Kaiser Engineersand California DivisionofHigh- employment withthe spanned 63years, including career asacivilengineer office after26years. His recently closedhisSonoma projects throughout the world. of majorwaterandsewer design andconstruction years ofworkingonthe retired in1999aftermany neering-Science, Inc.He president and CEO ofEngi- the City of Burbank and as serving as city engineer for practice, which included career in public and private California, had a 51-year CE) ofSanClemente, (B.S.’49 (B.S.’48 Presidential Medal of Honor.of Medal Presidential Korea’sSouth of recipient a and Engineering of Academy National U.S. the of member a was he teacher,and scholar lifelong A phenomena. tion primary design engineer on multiple patents. multiple on engineer design primary the was and engineer aeronautical an as NASA for worked He 81. age at May in died California, NORMAN E. SORENSEN E. NORMAN PAEK UN-CHUL

courtesy andy ryan engineered liver. engineered tissue- a with mouse humanized a creating in work groundbreaking her for Prize Student Lemelson-MIT year’sprestigious this won Chen A. PRIZEWORTHY:Alice (M.S.’65, Ph.D.’69 ME) of ME) Ph.D.’69 (M.S.’65, by julianna fleming julianna by waysstudying of human liver biology and diseases, such asmalaria and hepatitis C. efficient.”more and samples,”patient informativemore mouse the says,Chen of] [studies“making differentfromderived be liverscould these mouse. one into implantedof “Each micrometer-sized,as be livers can small multiple as engineered be can implants ricatedozens implants, of then an additional week for each implant to develop fully. fab- to hours few a just Chentakeslens. Itcontact a to appearance and size, shape own. its on function liver-likeassemble tomixture processesand leaves the then scaffold. She mer poly- synthetic a into them embeds and liver’s the matrix mimic extracellular that chemistries and livercells other liver)and the of tissue main the up make that process.development the in point earlier much a at humans affect could Of mice and livers livers and mice Of ogy and laser material interac - material laser and ogy technol- fiber optical on focused professor.a researchas His work Koreato South to returned then years, 22 for Jersey New in Labs May.Bell for worked He in Korea,died South Gwangju, In addition to improving drug testing,Chen’snew to drug improving lead to also may addition innovationIn the healthymouse. Because a into implanted surgically be then livercan The Theresulting implant looks nothing like anactual human liver and issimilar in cells To(the hepatocytes human providesliverimplant,Chen human a create (B.S.’51 ofME)Saratoga,

allowing researchers to predict how a new drug drug new a howresearcherspredict to allowing liver,human tissue-engineered a with mouse MIT,and Harvard humanized a createdChen at engineering biomedical in student graduate development. drug a efficientAs more and faster,in resultcould that safer technology a trials. clinical in participants human to dangerous potentially lengthy,and processcostlytesting as well as drug the make can This humans. to toxicity drug’s a show accurately to fails often mice on problems,createtesting can as this trials, drug blood.tocomes the When fromit drugs theirlivers, the organ that removes metabolized disease.and health human studying for model useful a mice genes,making their percentof 99 about share mammals two cheese. The for affinity an just than common havein moremiceHumans and 1986,he enjoyed working on computers as ahobby. Telescope.Space in retirementHubble his After the including projects,various on Martin Lockheed diedin January at age 84. He worked for 30 years at 96th birthday.96th his of short month a March, in died Mexico, New Berkeley Engineering. Berkeley and California of University the of supporter big a veteranand Army a World Warwas II He world. the throughout projects mining developing in career,instrumental his was of he course the Over industry.mining the in figure leading a became he where years, 33 for International Utah for worked May.in died California, He Hills, Altos Los of ALEXANDER “BUD” WILSON “BUD” ALEXANDER USIM WILLIAM STONE S. CHARLES ButAlice (B.S.’03A. Chen devised has BioE) are,Therehowever, differencesbetween stark (B.S.’50 EE) of Sunnyvale, California, (B.S.’39 ME) of Albuquerque, of ME) (B.S.’39 (B.S.’48 Metallurgy) (B.S.’48

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