medRxiv preprint doi: https://doi.org/10.1101/2021.04.18.21255521; this version posted April 20, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . Health effects of European colonization: An investigation of skeletal remains from 19th to early 20th century migrant settlers in South Australia Angela Gurr1, 2*, Jaliya Kumaratilake1, 2, Alan Henry Brook 3, 4, Stella Ioannou1, F. Donald Pate5, Maciej Henneberg1, 2, 5, 6 1. Biological Anthropology and Comparative Anatomy Research Unit, Adelaide Medical School, University of Adelaide, Adelaide, South Australia 2. Discipline of Anatomy and Pathology, Adelaide Medical School, University of Adelaide, Adelaide, South Australia 3. School of Dentistry, University of Adelaide, Adelaide, South Australia 4. Institute of Dentistry, Queen Mary, University of London, London, United Kingdom 5. Archaeology, Flinders University, Adelaide, South Australia 6. Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland Key words: Colonial Migration, Health, Economic Status, Metabolic Deficiencies, Adelaide Running title: Skeletal manifestations of health deficiencies in Colonial South Australia *Corresponding author: Email:
[email protected] (AG) Abstract Nineteenth century medical understanding of human metabolism was limited, therefore, the incidence of metabolic deficiencies was not fully recorded. In addition, the transition from agricultural based mode of life to the industrial one significantly changed the pattern of these metabolic deficiencies. They were further altered by colonisation of distant continents. Palaeopathological study of skeletal remains from the early industrialised colonial era allowed light to be shed on the metabolic stresses produced by this new mode of life.