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What You Can Expect at This Year's All-Virtual ENDO TUNE INTO ENDO2021 — MARCH 20–23, 2021 MARCH 2021 THE LEADING MAGAZINE FOR ENDOCRINOLOGISTS ● On the Right Track: How the many paths of G Protein-Coupled Receptors could lead to treatment breakthroughs in the future ● Opening Arguments: Both sides make their points about using radioactive iodine treatment for PREVIEW hyperthyroidism and its associated What You Can Expect at cancer risks ● No Place Like Home: How This Year’s All-Virtual ENDO environmental factors impact disparities in obesity treatment As this year’s annual conference transitions to online-only for the first time, the world’s leading experts in endocrine science and ● Lifetime Care: A comprehensive treatment converge to share the latest scientific discoveries and look at treating transgender patients cutting-edge breakthroughs in patient care. throughout their lives A CHEMIST AT HEART: In the lab with Richard J. Auchus, MD, PhD CRITICAL CARE: How COVID-19 impacted CGM use in hospitals NOW AVAILABLE TEST YOUR KNOWLEDGE WITH THE #1 SELF-ASSESSMENT TOOL IN THE FIELD • 120 brand-new case questions • Interactive online module with three learning modes • NEW! FLEXIBLE FORMAT OPTION: Select from a printed book or e-Book to complement the online module • Lab values in conventional and SI Units • 40.0 AMA PRA Category 1 Credits™ and ABIM MOC Points ORDER ONLINE AT ENDOCRINE.ORG/STORE © 2021 ENDOCRINE SOCIETY ESAP_2021_AD.indd 1 2/2/21 2:50 PM CLINICAL PRACTICE GUIDELINES FROM THE ENDOCRINE SOCIETY THE LEADING MAGAZINE FOR ENDOCRINOLOGISTS 2020 – 2022 EDITORIAL ADVISORY BOARD Henry Anhalt, DO Bergen County Pediatric Endocrinology Sally Camper, PhD Department of Human Genetics University of Michigan Medical School Rodolfo J. Galindo, MD Assistant Professor of Medicine Mount Sinai School of Medicine Christian M. Girgis, MBBS, PhD, FRACP Royal North Shore and Westmead Hospitals University of Sydney, Australia Lipid Management Andrea Gore, PhD Division of Pharmacology and Toxicology University of Texas in Patients with Daniel A. Gorelick, PhD Endocrine Disorders Baylor University, Houston, Texas M. Carol Greenlee, MD, FACP A NEW STANDARD FOR CARE Western Slope Endocrinology Grand Junction, Colo. (Faculty for Transforming Clinical Practice initiative [TCPi]) Learn the latest best practices Gary D. Hammer, MD, PhD Millie Schembechler Professor of Adrenal Cancer, for assessing and treating high Endocrine Oncology Program cholesterol in patients with endocrine University of Michigan diseases like hypothyroidism, Robert W. Lash, MD Chief Professional & Clinical Officer, Endocrine Society menopause, and Cushing Syndrome. Karl Nadolsky, DO Guideline Highlights: Assistant Clinical Professor of Medicine, Obtain a lipid panel in adults with endocrine MSU College of Human Medicine disorders to assess triglyceride levels and to SHMG Endocrinology calculate low-density lipoprotein cholesterol Joshua D. Safer, MD, FACP (LDL-C). Executive Director, Center for Transgender Medicine and Surgery Treat adults with type 2 diabetes and other Mount Sinai Health System cardiovascular risk factors with a statin in addition Professor of Medicine to lifestyle modi cations, aiming for an LDL-C goal Icahn School of Medicine at Mount Sinai of < 70 mg/dL. New York, NY Consider statin therapy, irrespective of the Shehzad Topiwala, MD, FACE cardiovascular risk score, in adults with type 1 Endocrinology Department diabetes who are age 40 years and older, and/or SevenHills Hospital, Mumbai, India have a history of diabetes of at least 20 years, and/ Kristen R. Vella, PhD or either microvascular complications, chronic Beth Israel Deaconess Medical Center kidney disease in stages 1-4, or obesity. Harvard Medical School Christina Wang, MD READ THE GUIDELINE AT UCLA Clinical and Translational Science Institute ENDOCRINE.ORG/LIPID2020 Harbor – UCLA Medical Center Mihail “Misha” Zilbermint, MD Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins University School of Medicine; Endocrinology, Diabetes and Metabolism, Suburban Hospital; © 2020 ENDOCRINE SOCIETY Johns Hopkins Community Physicians MARCH 2021 IN THIS ISSUE 18 | Lifetime Care: A Comprehensive Look at Treating Transgender Patients A relatively new field, transgender medicine will be featured in theENDO 2021 session, “Transgender Care: A Comprehensive Assessment for a Multi-Faceted Condition,” a live, 90-minute program taking place Sunday, March 21, 2021 at 12:15 p.m. Program co-chair, Stephen M. Rosenthal, MD, and Sabine E. Hannema, MD, PhD, talk to Endocrine News about what attendees can expect from the three varied programs that will each have moderated Q&A sessions with world-renowned experts. BY DEREK BAGLEY 22 | No Place Like Home: How Environmental Factors Impact Disparities in Obesity Treatment ENDO 2021 will feature “How Do We Confront Disparities in Obesity and COVID-19 Treatment?” which will have three different programs with individual Q&A sessions on Monday, March 22 at 12:15 p.m. Rebecca E. Hasson, PhD, FACSM, highlights what attendees can expect from her presentation on obesity-related metabolic risk factors caused by one’s environment. 14 BY DEREK BAGLEY 14 | Opening 28 | Plenary Pioneers, Part II: On the Right Track: Arguments: Debating How the Many Paths of GPCRs Could Lead to Treatment Breakthroughs the Use of Radioactive Iodine At ENDO 2021, the first time the Endocrine Society’s annual conference has gone all-virtual, a live Treatment for Hyperthyroidism Presidential Plenary on March 20 will feature a pair of presentations on the latest developments in basic tissue engineering. Nobel Prize winner Brian Kobilka, MD, talks to Endocrine News about his session, The controversy around the use “Structural Insights into G Protein-Coupled Receptor Activation: Implications for Drug Discovery.” of radioactive iodine to treat BY KELLY HORVATH hyperthyroidism will be addressed at this year’s all-virtual ENDO 2021 in the session, “Does the Treatment of 32 | Critical Care: Hyperthyroidism Lead to Cancer?” Both How COVID-19 Response Could Advance Use of CGM in Hospitals sides of this issue give us a preview of Several studies have shown the effectiveness of continuous glucose monitoring in treating hospitalized what to expect from what promises to be COVID-19 patients with diabetes. As nurses and other healthcare staff enthusiastically accept the use of a lively discussion. these devices, a significant cost benefit was also found. BY KELLY HORVATH BY ERIC SEABORG 4 | PRESIDENT’S VIEWPOINT drug shows promise in treating of the world’s leading experts on 45 | HORMONE HEALTH A Cause for Celebration in diabetic macular edema. steroid-related diseases, and what NETWORK Unprecedented Times BY DEREK BAGLEY research his lab is planning in the Estrogen Fact Sheet future. 6 | FROM THE EDITOR 12 | ENDOCRINE ITINERARY BY GLENDA FAUNTLEROY SHAW ENDO 2021: An Annual Scientific meetings of interest Conference From the Comfort — to endocrinologists from around 40 | ADVOCACY and Safety — of Home the world Society to school Congress on obesity; Members virtually advocate 8 | TRENDS & INSIGHTS 38 | LABORATORY NOTES on the Hill for research funding; www.endocrine.org Health disparities in diabetes A CHEMIST AT HEART Congress focuses on COVID-19 require a broader look at Endocrine News talks with 2021 relief/recovery legislation; and Follow us on Twitter: systemic racism; Myriad factors Outstanding Clinical Investigator Biden administration weighs in on @Endocrine_News linked to metabolic pregnancy Laureate Award recipient Richard J. ACA as SCOTUS decision expected complications; COVID-19 may Auchus, MD, PhD, who reflects on by June. reduce fertility in men; and New his career, how he became one 2 | MARCH 2021 | ENDOCRINENEWS.ORG PRESIDENT’S VIEWPOINT A Cause for Celebration in Unprecedented Times hen my predecessor, then-president E. Dale Abel, with our scientific and clinical colleagues, and of course, MD, PhD, made the difficult but wise decision our patients. Obviating traditional barriers such as time to cancel ENDO 2020, and then passed me the and distance, this new normal has propelled us forward and Wpresidential gavel in our virtual Annual Business Meeting in already demonstrated meaningful benefits for our expanding early April 2020, we had no idea that the pandemic was going community. to consume the entire year and result in a second virtual annual meeting, ENDO 2021, some 12 months later. I want to thank past-president Abel, the chairs of the 2020 Annual Meeting Steering Committee (AMSC), and the It is within this challenging time that our organization was amazing staff who worked with them to quickly pivot and, in tested, opportunities were born, and our global leadership a couple of months, created a virtual conference, the first of its became increasingly manifest. I would like to dedicate my kind. ENDO Online 2020 was a major success, attracting more last presidential letter to you — our members, my colleagues. than 27,000 registrants and 17,000 attendees, the largest event As stated in Strategic Plan 4, “We envision a world in which in our longstanding history! The event provided live and on- advances in endocrine science, education, and care promote demand programming and was offered free to all participants, optimal health and well-being.” In spite of the enormous members and non-members alike. In September, we delivered obstacles and challenges we have faced as families, clinicians, our first ever virtual Clinical Endocrinology Update (CEU) and Endocrine Board Review (EBR) meetings. Collectively, these meetings attracted more than
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