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ANNALES UNIVERSITATIS MARIAE CURIE-SKŁODOWSKA KOMITET REDAKCYJNY REDAKTOR NACZELNY Ryszard Szczygieł

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ANNALES UNIVERSITATIS MARIAE CURIE-SKŁODOWSKA KOMITET REDAKCYJNY REDAKTOR NACZELNY Ryszard Szczygieł ANNALES UNIVERSITATIS MARIAE CURIE-SKŁODOWSKA KOMITET REDAKCYJNY REDAKTOR NACZELNY Ryszard Szczygieł REDAKTORZY SEKCJI A MATHEMATICA Stanisław Prus AA CHEMIA Władysław Rudziński AAA PHYSICA Karol I.Wysokiński AI INFORMATICA Paweł Mikołajczak B GEOGRAPHIA Maria Łanczot GEOLOGIA ETC. C BIOLOGIA Teresa Jakubowicz D MEDICINA Maria Majdan DD MEDICINA VETERINARIA Zdzisław Gliński DDD PHARMACIA Jolanta H.Kotlińska E AGRICULTURA Marianna Warda EE ZOOTECHNICA Mirosław Pięta EEE HORTICULTURA Magdalena Gantner F HISTORIA Małgorzata Willaume FF PHILOLOGIAE Maria Woźniakiewicz-Dziadosz G IUS Romuald Kmiecik H OECONOMIA Urszula Wich I PHILOSOPHIA Lesław Hostyński – SOCIOLOGIA Jolanta Zdybel – zastępca redaktora J PEDAGOGIA Anna Herzyk – PSYCHOLOGIA Ewa. M. Szepietowska – zastępca redaktora K POLITOLOGIA Włodzimierz Mich L ARTES Gabriela Klauza Table of contents Table of contents ANNALES ANNALESUNIVERSITATISANNALESUNIVERSITATIS MARIAE CURIE-SKŁODOWSKACURIE-SKŁODOWSKA UNIVERSITATIS MARIAE CURIE-SKŁODOWSKA SECTIO DDD SECTIO DDD SECTIO DDD PHARMACIA PHARMACIAPHARMACIA 3 3 VOL. XXII,XXIII, N N 3 3 LUBLIN 20092010 VOL. XXII, N 3 LUBLIN 2009 UNIWERSYTETUNIWERSYTET MARII CURIE-SKŁODOWSKIEJ CURIE-SKŁODOWSKIEJ UNIWERSYTETUNIWERSYTETUNIWERSYTET MARII CURIE-SKŁODOWSKIEJMEDYCZNY UNIWERSYTETISSNISSN 0867-06090867-0609 MEDYCZNY ISSN 0867-0609 Editorial Board List EDITOR-IN-CHIEF Jolanta H. Kotlinska, Lublin, Poland ASSISTANT EDITOR Barbara Tromczynska, Lublin, Poland EDITORIAL BOARD Janusz Solski, Lublin, Poland Aleksander Sklarow, Lvov, Ukraine Roman Kaliszan, Gdańsk, Poland Kazimierz Glowniak, Lublin, Poland Krystyna Olczyk, Katowice, Poland Roman Lesyk, Lvolv, Ukraine Rudolf Bauer, Graz, Austria Yue-Wei Guo, Shanghai, People’s Republic of China Alexios L. Skaltsounis, Athenes, Greece Robert Verpoorte, Leiden, Nederlands Rafal Kaminski, Braine-l’Alleud, Belgium Maciej Gasior, West Chester, PA, U.S.A. Jerzy Silberring, Krakow, Poland Stanisław J. Czuczwar, Lublin, Poland Jarmila Vinsova, Hradec Kralove, Czech Republic Dariusz Matosiuk, Lublin, Poland Sylwia Fidecka, Lublin, Poland Krzysztof Jozwiak, Lublin, Poland Monika Waksmundzka-Hajnos, Lublin, Poland Anna Malm, Lublin, Poland Grazyna Ginalska, Lublin, Poland Anna Gumieniczek, Lublin, Poland Ewa Jagiello-Wojtowicz, Lublin, Poland Edited by Danuta Slowikowska, Lublin, Poland Tomasz Baj, Lublin, Poland Language Editors Hanna Grygielska-Michalak, Lublin, Poland ISSN 0867-0609 Adres Redakcji: ul. Staszica 4, 20-081 Lublin Skład i Druk: EXPOL P. Rybiński, J. Dąbek Sp J. 87-800 Włocławek, tel.fax (54) 232 37 23 ANNALES UNIVERSITATIS MARIAE CURIE-SKŁODOWSKA LUBLIN – POLONIA VOL. XXIII, N 3, SECTIO DDD 2010 Table of contents Spis treści 1. BEATA WOJTYSIAK-DUMA, AGATA BURSKA, ARLETA MALECHA-JĘDRASZEK, DARIUSZ DUMA, HELENA DONICA sVCAM-1 levels in patients with type 2 diabetes mellitus with micro- and macrovascular complications Poziomy sVCAM-1 u pacjentów z cukrzycą typu 2 z powikłaniami mikro- i makronaczyniowymi 11 2. URSZULA KOSIKOWSKA, MAREK JUDA, AGNIESZKA GRZEGORCZYK, ANNA BIERNASIUK, ANNA MALM A comparison of colonization of the upper respiratory tract by Haemophilus influenzae and Staphylococcus aureus in healthy pre-school children exposed and unexposed to tobacco smoke Porównanie kolonizacji górnych dróg oddechowych przez Haemophilus influenzae i Staphylococcus aureus u zdrowych dzieci w wieku przedszkolnym eksponowanych i nieeksponowanych na dym tytoniowy 21 3. JOLANTA RZYMOWSKA, PIOTR MAJ Paclitaxel and apoptosis in breast cancer cells Paklitaksel i apoptoza w komórkach raka gruczołu piersiowego 27 4. JUSTYNA ZALEWSKA, GRAŻYNA GINALSKA, WOJCIECH BRZANA Amikacin-modified hybrid biomaterial biological properties Właściwości biologiczne hybrydowego biomateriału modyfikowanego amikacyną 35 5. BARBARA MADEJ, MAŁGORZATA PIASECKA-TWARÓG, WOJCIECH DWORZAŃSKI, WOJCIECH CHROMIŃSKI, EWA NIEZABITOWSKA, FRANCISZEK BURDAN Breast cancer – an epidemiological and social problem in Poland Rak gruczołu piersiowego – problem epidemiologiczny i społeczny w Polsce 41 6 Table of contents 6. ELWIRA SIENIAWSKA, TOMASZ BAJ , KAZIMIERZ GŁOWNIAK Influence of the preliminary sample preparation on the tannins content in the extracts obtained from Mutellina purpurea Poir. Wpływ przygotowania próbki na zawartość garbników w ekstraktach z Mutellina purpurea Poir. 47 7. TOMASZ BAJ, RADOSŁAW KOWALSKI, ŁUKASZ ŚWIĄTEK, MAŁGORZATA MODZELEWSKA, TADEUSZ WOLSKI Chemical composition and antioxidant activity of the essentials oil of hyssop (Hyssopus officinalis L. ssp. officinalis) Skład chemiczny oraz aktywność antyoksydacyjna olejku eterycznego z hyzopu lekarskiego (Hyssopus officinalisL. ssp. officinalis) 55 8. ANDRZEJ NOWAKOWSKI, BEATA MATUSZEK Acute complications of diabetes – the present state of knowledge. Part I. Diabetic ketoacidosis Ostre powikłania cukrzycy – stan wiedzy. Cz. I . Cukrzycowa kwasica ketonowa 63 9. AGNIESZKA ŁAGOWSKA-BATYRA, BEATA MATUSZEK, MONIKA LENART-LIPIŃSKA, KATARZYNA STRAWA-ZAKOŚCIELNA, ANDRZEJ NOWAKOWSKI Comparison of the course of type 2 diabetes in village and town inhabitants in the Lublin region Porównanie przebiegu cukrzycy typu 2 u mieszkańców wsi i miast regionu lubelskiego 69 10. KATARZYNA PARADOWSKA, GRAŻYNA GINALSKA Phosphoglucose isomerase – “portrait of the protein with many faces” Izomeraza fosfoglukozowa – „portret białka o wielu twarzach” 79 11. KATARZYNA PARADOWSKA, BARBARA BEDNARZ, GRAŻYNA GINALSKA Phosphoglucose isomerase from Escherichia coli ATCC 25922 – pilot studies Izomeraza fosfoglukozowa z Escherichia coli ATCC 25922- badania pilotowe 87 12. MARIA KUROWSKA, JERZY S. TARACH, JOANNA MALICKA, HELENA JANKOWSKA, ANNA DĄBROWSKA Islet GAD autoantibodies in patients with newly diagnosed type 2 diabetes Autoprzeciwciała przeciw wyspowe anty GAD u chorych z nowo rozpoznaną cukrzycą typu 2 101 13. KINGA TENDERA, MARTA KRUK, GRAŻYNA BIAŁA Alzheimer’s disease: causes, symptoms and pharmacotherapy Choroba Alzheimera: przyczyny, objawy i farmakoterapia 107 Table of contents 7 14. MONIKA KARAŚ, ANNA JAKUBCZYK, BARBARA BARANIAK Antiradical and antihypertensive activity of peptides obtained from proteins pea sprouts (Pisum sativum) by enzymatic hydrolysis Antyrodnikowa i antynadciśnieniowa aktywność peptydów otrzymanych w wyniku enzymatycznej hydrolizy białek kiełków grochu (Pisum sativum) 115 15. JADWIGA BŁONIARZ, STANISŁAW ZARĘBA Evaluation of some macroelement levels in selected dietary supplements supporting the immune system of the human organism Ocena zawartości niektórych makroelementów w wybranych suplementach diety wspomagających system odpornościowy organizmu ludzkiego 123 16. JAROGNIEW J. ŁUSZCZKI, ANNA JASKÓLSKA, WOJCIECH DWORZAŃSKI, DOROTA ŻÓŁKOWSKA Effect of 7-nitroindazole and NG-nitro-L-arginine on the protective action of clobazam in the maximal electroshock-induced seizures in mice Wpływ 7-nitroindazolu i NG-nitro-L-argininy na ochronne działanie klobazamu w teście maksymalnego wstrząsu elektrycznego u myszy 135 17. JAROGNIEW J. ŁUSZCZKI, ANNA RĘKAS, LECH P. MAZURKIEWICZ, MICHAŁ GLEŃSK, GRAŻYNA OSSOWSKA Effect of osthole on the protective activity of carbamazepine and phenobarbital against maximal electroshock-induced seizures in mice Wpływ ostolu na ochronne działanie karbamazepiny i fenobarbitalu w teście maksymalnego wstrząsu elektrycznego u myszy 145 18. ANDRIY SUKHOMLYN, KARINE NEPORADA Experimental correction of pathological changes in salivary glands by multiprobiotic Symbiter® acidofilus under conditions of hypergastrinemia Doświadczalna korekcja zmian patologicznych gruczołów ślinowych pod wpływem multiprobiotyku Symbiter® acidofilus w warunkach hipergastrynemii 157 19. ANNA KRYSHCHYSHYN, BORYS ZIMENKOVSKY, ROMAN LESYK Synthesis of novel fused thiopyrano[2,3-d]thiazole derivatives as potential anticancer agents Synteza nowych pochodnych tiopirano[2,3-d]tiazolu jako potencjalnych leków przeciwnowotworowych 163 20. ANNA KULINICH, ANNA MASLAK, IRYNA PISMENETSKAYA, OLEKSANDER MINCHENKO, OLGA SHEVCHENKO, ALLA SHEVTSOVA Investigation of fibronectin expression by white blood cells in diffuse liver disease of viral etiology Badania nad ekspresją fibronektyny przez krwinki białe w rozlanych chorobach miąższu wątroby o etiologii wirusowej 169 8 Table of contents 21. DMYTRO HAVRYLYUK, NATALIYA KOVACH, BORYS ZIMENKOVSKY, ROMAN LESYK Synthesis of new 4-azolidinones with 3,5-diaryl-4,5-dihydropyrazole moiety and evaluation of their antitumor activity in vitro Synteza nowych 4-azolidynonów z cząsteczką 3,5-diaryl-4,5-dihydropirazolu i ocena ich aktywności przeciwnowotworowej in vitro 173 22. DMYTRO MINCHENKO, OLENA HUBENYA, BOHDAN TERLETSKY, ANASTASIYA KUZNETSOVA, MICHEL MOENNER, OLEKSANDR MINCHENKO Blockade of the endoplasmic reticulum stress sensor inositol requiring enzyme-1 changes the expression of cyclin and growth arrest-specific genes in glioma cells Blokada enzymu-1 zależnego od inozytolu sensora stresu retikulum endoplazmatycznego zmienia ekspresję cyklin genów hamujących wzrost (GAS) w komórkach glejaka 179 23. DMYTRO Z. VOROBETS Ca2+-transporting ATP-hydrolyzing systems activity in lymphocytes of peripheral blood from men with erectile dysfunction Aktywność systemów hydrolizujących ATP zależnych od Ca2+ w limfocytach krwi obwodowej mężczyzn z zaburzeniami erekcji 185 24. OLENA FILINSKA, SVITLANA YABLONSKA, SERGIY MANDRYK, IRYNA KHARCHUK, IRYNA KOTLYAR, GALYNA OSTROVSKA, VOLODYMYR RYBALCHENKO Effect of maleimide derivative on oxidative stress and glutathione antioxidant system in 1,2-dimethylhydrazine induced colon carcinogenesis in rat Wpływ pochodnych maleimidu na
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