Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice Against SARS-Cov-2 Infection
viruses Article Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection Sandro Halwe 1,2 , Alexandra Kupke 1,2 , Kanika Vanshylla 3 , Falk Liberta 4 , Henning Gruell 3 , Matthias Zehner 3, Cornelius Rohde 1,2 , Verena Krähling 1,2, Michelle Gellhorn Serra 1,2 , Christoph Kreer 3 , Michael Klüver 1,2 , Lucie Sauerhering 1,2, Jörg Schmidt 1,2 , Zheng Cai 5, Fei Han 5, David Young 5, Guangwei Yang 5, Marek Widera 6 , Manuel Koch 7,8 , Anke Werner 1 , Lennart Kämper 1, Nico Becker 1, Michael S. Marlow 5, Markus Eickmann 1, Sandra Ciesek 6,9,10 , Felix Schiele 4, Florian Klein 3,7,11 and Stephan Becker 1,2,* 1 Institute of Virology, Philipps University Marburg, Hans-Meerwein-Straße 2, 35043 Marburg, Germany; halwes@staff.uni-marburg.de (S.H.); kupke@staff.uni-marburg.de (A.K.); rohdecor@staff.uni-marburg.de (C.R.); kraehliv@uni-marburg.de (V.K.); michelle.gellhornserra@uni-marburg.de (M.G.S.); michael.kluever@staff.uni-marburg.de (M.K.); lucie.sauerhering@staff.uni-marburg.de (L.S.); schmidt3@staff.uni-marburg.de (J.S.); wernera4@staff.uni-marburg.de (A.W.); kaemper@staff.uni-marburg.de (L.K.); nico.becker@uni-marburg.de (N.B.); eickmann@staff.uni-marburg.de (M.E.) 2 German Center for Infection Research (DZIF), Partner Site Giessen-Marburg-Langen, 35043 Marburg, Germany 3 Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany; kanika.vanshylla@uk-koeln.de (K.V.); henning.gruell@uk-koeln.de (H.G.); matthias.zehner@uk-koeln.de (M.Z.); christoph.kreer@uk-koeln.de (C.K.); florian.klein@uk-koeln.de (F.K.) Citation: Halwe, S.; Kupke, A.; 4 Biotherapeutics Discovery, Boehringer Ingelheim Pharma GmbH & Co.
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