Microbiology and Molecular Genetics 1

Total Page:16

File Type:pdf, Size:1020Kb

Microbiology and Molecular Genetics 1 Microbiology and Molecular Genetics 1 For certification and completion of the BS degree, students will take MICROBIOLOGY AND one year of clinical internship in program accredited by the National Accrediting Agency for Clinical Laboratory Science (NAACLS) and MOLECULAR GENETICS affiliated with Oklahoma State University. Students have the options of the following hospitals/programs: Comanche County Memorial Hospital, Microbiology/Cell and Molecular Biology Lawton, OK; St. Francis Hospital, Tulsa, OK; Mercy Hospital, Ada, OK; Mercy Hospital, Ardmore, OK. Microbiology is the hands-on study of bacteria, viruses, fungi and algae and their many relationships to humans, animals, plants and the Medical Laboratory Science is unique in allowing students to enter environment. Cell and molecular biology bridges the fields of chemistry, the health profession directly after obtaining a BS degree. Clinical biochemistry and biology as it seeks to understand life and cellular laboratory scientists comprise the third-largest segment of the healthcare processes at the molecular level. Microbiologists apply their knowledge professions and are an important member of the healthcare team, to infectious diseases and pathogenic mechanisms; food production working alongside doctors and nurses. Students who complete and preservation, industrial fermentations which produce chemicals, Microbiology/Cell and Molecular Biology with the MLS option enjoy a drugs, antibiotics, alcoholic beverages and various food products; 100% employment rate upon graduation. biodegradation of toxic chemicals and other materials present in the environment; insect pathology; the exciting and expanding field of Courses biotechnology which endeavors to utilize living organisms to solve GENE 5102 Molecular Genetics important problems in medicine, agriculture, and environmental science; Prerequisites: BIOC 3653 or MICR 3033 and one course in genetics or infectious diseases; and public health and sanitation. consent of instructor. Microbes live in every imaginable habitat. They generate two-thirds of Description: An introduction to molecular genetics on the graduate level. the oxygen in our atmosphere, drive the geochemical cycles that make Credit hours: 2 life on Earth sustainable and are the basis of every food web. As model Contact hours: Lecture: 2 Contact: 2 organisms used for basic research, microbes have contributed more Levels: Graduate than any other organisms to the current knowledge of genetics at the Schedule types: Lecture molecular level and genomics. Department/School: Graduate College MICR 1211 First Year Microbiology Laboratory Experience In contrast to the enormous benefits derived from some microbes, other Prerequisites: MCMB major and concurrent enrollment in A&S 1111. microorganisms and viruses are the causative agents of infectious Description: This laboratory course is designed for First Year majors disease and hence have a devastating impact on humanity. These to experience microbiology in parallel with A&S 1111. Students will pathogens are the subjects of research into the mechanisms of apply pure culture technique to obtain and characterize environmental infections, with the ultimate goal of combating or preventing diseases. isolates. Students also will learn light microscopy skills, anaerobic culture Departmental courses are designed to provide comprehensive training technique, and molecular biology skills. and the skills required for working with microorganisms in a professional Credit hours: 1 setting, as well as a broad understanding of all aspects of microbial Contact hours: Lab: 2 Contact: 2 life. The lecture courses are taught by tenured faculty members and the Levels: Undergraduate laboratory courses are designed to integrate classroom learning with Schedule types: Lab hands-on research experience. Department/School: Microbiology & Mol Gen MICR 1513 Inquiry-Based Biology Opportunities for employment exist at all scholarly levels, in many local, Description: Directed inquiry and hands-on study of biological principles. state and national agencies and industry. The record for employment Restricted to elementary education majors or related fields as model of microbiologists has been excellent for many years and with the course to learn and teach science. increased interest in biotechnology, medicine and the human microbiome, Credit hours: 3 employment opportunities look even brighter for the future. Contact hours: Lecture: 1 Lab: 4 Contact: 5 Levels: Undergraduate Microbiology is the strongest possible foundation for students who Schedule types: Lab, Lecture, Combined lecture and lab wish to go to medical, dental, veterinary or graduate schools. We take Department/School: Microbiology & Mol Gen pride in offering research and internship opportunities that prepare students for careers in the biomedical sciences. Our graduates find jobs MICR 2123 Introduction to Microbiology in medicine, health care, medical laboratories, teaching, research, industry Prerequisites: Grade of "C" or better in BIOL 1114 and either CHEM 1215 and government. or CHEM 1314 with a grade of "C" or better or concurrent enrollment in one. Medical Laboratory Science Option Description: General principles of the biology of microorganisms, This option is designed to give students the broad general education and including bacteria, viruses, algae, fungi, protozoa and archaea. Course the technical skills that are required for a successful career in medical previously offered as MICR 2125. laboratory science (MLS). The minimum requirement for the BS degree Credit hours: 3 in Microbiology/Cell and Molecular Biology with the (MLS) option is Contact hours: Lecture: 3 Contact: 3 three years of university work that includes general chemistry, organic Levels: Undergraduate chemistry, biochemistry, immunology, genetics, anatomy & physiology, Schedule types: Lecture physics, upper-division courses in microbiology, and one year of clinical Department/School: Microbiology & Mol Gen laboratory education (internship). 2 Microbiology and Molecular Genetics MICR 2132 Introduction to Microbiology Laboratory MICR 3154 Food Microbiology Prerequisites: MICR 2123 or concurrent enrollment. Prerequisites: Minimum grade of "C" in (MICR 2123 and MICR 2132) and Description: Laboratory safety, aseptic technique, microscopy, staining (CHEM 3013 or CHEM 3053). and culture techniques, collection of microbial samples, isolation and Description: Relationship of microorganisms to food manufacture and identification of microorganisms, microbial growth and basic principles preservation, to food spoilage and microbial food poisoning and to of metabolism, environmental microbiology, other discipline specific various aspects of primary food production. Same course as FDSC 3154. laboratory skills. Course previously offered as ANSI 3154. Credit hours: 2 Credit hours: 4 Contact hours: Lab: 4 Contact: 4 Contact hours: Lecture: 2 Lab: 4 Contact: 6 Levels: Undergraduate Levels: Undergraduate Schedule types: Lab Schedule types: Lab, Lecture, Combined lecture and lab Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen MICR 2890 Honors Experience in Microbiology MICR 3223 Advanced Microbiology Prerequisites: Honors Program participation and concurrent enrollment in Prerequisites: Concurrent enrollment or completion of CHEM 3013 or a designated MICR course. CHEM 3053 and minimum grade of "C" in MICR 2123 and MICR 2132. Description: A supplemental Honors experience in Microbiology to Description: Subcellular structure and function of microorganisms. partner concurrently with designated MICR 2123 and/or MICR 2132 Synthesis, translocation, and metabolism of cellular macromolecular course(s). This course adds a different intellectual dimension to the constituents. Substrate transport and metabolism. Course previously designated course(s). offered as MICR 3224 and MICR 4224. Credit hours: 1 Credit hours: 3 Contact hours: Lecture: 1 Contact: 1 Contact hours: Lecture: 3 Contact: 3 Levels: Undergraduate Levels: Undergraduate Schedule types: Lecture Schedule types: Lecture Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen General Education and other Course Attributes: Honors Credit MICR 3233 Foundations of Cancer Biology MICR 3033 Cell and Molecular Biology Prerequisites: Two of the following four courses: MICR 2123; CHEM 3053; Prerequisites: MICR 2123 and MICR 2132 with "C" or better or BOT 1404 MICR 3033; BIOL 3023. or ZOOL 1604 and CHEM 1225 or CHEM 1515 or equivalent with a grade Description: The foundations of cancer biology will be presented in of "C" or better. a systematic and generally accessible manner. Developments in the Description: The cell concept and cell morphology, cell macromolecules, understanding, treatment and prevention of cancer will be used to organelles, enzymes, energetics, movement of water and materials illustrate both setbacks and victories in applying the scientific method across membranes, influence of external environment, cellular synthesis, to a biological process. The methods and models used to understand growth and maintenance, control and integration of function, replication, cancer, and the evidence for and assumptions made in these approaches differentiation, origin, and evolution of cells. Course previously offered as will be discussed. Students will select a topic related to cancer biology CLML 3014, BIOL 3014, and BISC 3014. and will write a scientific essay on this topic. Credit hours: 3 Credit hours: 3 Contact hours: Lecture: 3 Contact:
Recommended publications
  • Journal of Microbiology, Immunology and Infection
    JOURNAL OF MICROBIOLOGY, IMMUNOLOGY AND INFECTION AUTHOR INFORMATION PACK TABLE OF CONTENTS XXX . • Description p.1 • Impact Factor p.1 • Abstracting and Indexing p.2 • Editorial Board p.2 • Guide for Authors p.4 ISSN: 1684-1182 DESCRIPTION . Journal of Microbiology, Immunology and Infection, launched in 1968, is the official bi-monthly publication of the Taiwan Society of Microbiology, the Chinese Society of Immunology, the Infectious Diseases Society of Taiwan and the Taiwan Society of Parasitology. The journal is an open access journal, committed to disseminating information on the latest trends and advances in microbiology, immunology, infectious diseases and parasitology. Articles on clinical or laboratory investigations of relevance to microbiology, immunology, infectious diseases, parasitology and other related fields that are of interest to the medical profession are eligible for consideration. Article types considered include perspectives, review articles, original articles, brief reports and correspondence. The Editorial Board of the Journal comprises a dedicated team of local and international experts in the field of microbiology, immunology, infectious diseases and parasitology. All members of the Editorial Board actively guide and set the direction of the journal. With the aim of promoting effective and accurate scientific information, an expert panel of referees constitutes the backbone of the peer- review process in evaluating the quality and content of manuscripts submitted for publication. JMII is open access and indexed in SCIE, PubMed, MEDLINE, EMBASE, Scopus, AIDS & Cancer Reseach, CABI, BIOSIS Previews, Biological Abstracts, EBSCOhost, CancerLit, Reactions Weekly (online), Chemical Abstracts, HealthSTAR, Global Health, ProQuest. Benefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more.
    [Show full text]
  • Bacterial Secretion: Caught in The
    RESEARCH HIGHLIGHTS IN BRIEF VIRAL INFECTION ΦX174 crosses the border Tailed phages transport their genomes into bacterial cells using their tail, whereas most tail-less phages use a host cell-encoded channel. One interesting exception is the icosahedral phage ΦX174, which is devoid of an external tail but instead uses the genome-associated DNA pilot protein H for DNA delivery. Sun et al. solved the crystal structure of protein H at 2.4 Å resolution and showed that its ten identical α-helical monomers are organized into a 170 Å-long α-barrel. This decameric coiled-coil contains transmembrane domains at each end, which may anchor the channel to the bacterial inner and outer cell membranes. The authors further found that H protein oligomerization is important for infectivity but not for particle formation. Using cryo-electon tomography, they went on to show that, following attachment of the ΦX174‑like phage ST‑1 to Escherichia coli mini cells, the virus extrudes a putative H tube for DNA transport across the periplasmic space. This tube is disassembled after DNA translocation. ORIGINAL RESEARCH PAPER Sun, L. et al. Icosahedral bacteriophage ΦX174 forms a tail for DNA transport during infection. Nature http://dx.doi.org/10.1038/nature12816 (2013) CELLULAR MICROBIOLOGY Getting moving in the cytoplasm In contrast to eukaryotes, bacteria lack cytoskeletal motor proteins and thus rely on diffusion for intracellular transport. The physical properties of the bacterial cytoplasm, which determine cytoplasmic dynamics and thus influence intracellular processes, are poorly understood. Using single-particle tracking of cellular components, such as poly- hydroxyalkanoate storage granules and crescentin filaments, as well as foreign particles, the authors show that the bacterial cytoplasm has similar characteristics to glass-forming liquids.
    [Show full text]
  • Biofilms and Biodiversity: an Interactive Exploration of Aquatic
    Journal of Industrial Microbiology & Biotechnology (2000) 24, 334–338 2000 Society for Industrial Microbiology 1367-5435/00 $15.00 www.nature.com/jim Biofilms and biodiversity: an interactive exploration of aquatic microbial biotechnology and ecology JA Frederick1, D Jacobs2 and WR Jones3 1Maryland Sea Grant Extension Program, Columbus Center, 701 E Pratt St, Baltimore, MD 21202; 2Maryland Sea Grant, 0112 Skinner Hall, College Park, MD 20742; 3Center of Marine Biotechnology, University of Maryland Biotechnology Institute, 701 E Pratt St, Baltimore, MD 21202, USA The study of biofilms provides a unique educational opportunity to examine ecosystems, biodiversity and appli- cations of environmental biotechnology. There are many variables that could be studied for measuring the interac- tions between bacterial biofilms and invertebrate biodiversity as a method for assessing the health of aquatic eco- systems. These interactions also lend themselves to an easily replicated model system which can be used to reach a wide audience with an educational opportunity for students as well as a professional development opportunity for teachers. At the foundation of the research are invaluable basic microbiology skills: strain collection, isolation, cultivation and characterization. Through the additional process of characterizing, identifying and enumerating invertebrate organisms that attach to bacterial biofilms in aquatic ecosystems, there evolved a multidisciplinary class laboratory activity that has found broad application. This activity is captivating not only to undergraduate microbiology students but to middle and high school students and their teachers. The demand for information about the activity has led to the development of a truly interactive web-based lesson, which in turn has resulted in additional inquiries and further refinement of the lesson as an undergraduate independent research course.
    [Show full text]
  • Microbiology
    www.Padasalai.Net www.TrbTnpsc.com GOVERNMENT OF TAMIL NADU MICROBIOLOGY HIGHER SECONDARY FIRST YEAR Untouchability is Inhuman and a Crime A publication under Free Textbook Programme of Government of Tamil Nadu Department of School Education http://www.trbtnpsc.com/2018/05/tamilnadu-scert-new-school-books-and-ebooks-download-from-text-books-online.html www.Padasalai.Net www.TrbTnpsc.com Government of Tamil Nadu First Edition - 2018 NOT FOR SALE Content Creation The wise possess all State Council of Educational Research and Training © SCERT 2018 Printing & Publishing Tamil NaduTextbook and Educational Services Corporation www.textbooksonline.tn.nic.in II http://www.trbtnpsc.com/2018/05/tamilnadu-scert-new-school-books-and-ebooks-download-from-text-books-online.html www.Padasalai.Net www.TrbTnpsc.com Contents Chapter 1 Introduction to Microbiology ...............................................01 Chapter 2 Microscopy .............................................................................15 Chapter 3 Stains and Staining Methods .................................................25 Chapter 4 Sterilization .............................................................................40 Chapter 5 Cultivation of Microorganisms .............................................53 Chapter 6 Microbial Nutrition and Growth ..........................................72 Chapter 7 Morphology of Bacteria .........................................................88 Chapter 8 Microbial Taxonomy ............................................................113
    [Show full text]
  • BIOD17 Seminars in Cellular Microbiology Course Outline ! Winter 2015 BIOD17 Offers an Overview of the Basic and Most Significant Advances in Cellular Microbiology
    BIOD17 Seminars in Cellular Microbiology Course Outline ! Winter 2015 BIOD17 offers an overview of the basic and most significant advances in cellular microbiology. This discipline studies the interplays between pathogenic bacteria and mammalian cells, combining knowledge and techniques from cell biology and microbiology. The curricula of BIODI7 includes the study of bacterial pathogenic mechanisms, specially those related to bacteria invasion and replication in mammalian host cells. Students will be provided with research papers and reviews on pathogenic microorganism and attend to lectures in selected topics relevant to the field. Students will work in teams to present seminars on research papers and to debate in class. Also, students will have to write, individually, 3 assignments on scientific papers. At the end of the term, it is expected that students will be able to understand and !critically analyze scientific literature in the field of cellular microbiology. ! ! Course structure and grading: ! 1- Lectures Lectures will be provided during the first 2 weeks of class, total time: 6h . The lectures are aimed to introduce the students theoretical and methodological concepts on Cellular Microbiology. Lecture slides will be uploaded to the intranet ! 24h in advance. 2- Assignments ! You will have to answer 3 questioners on research articles. The assignments will consist on 10-15 questions that must be answered !individually and e-mailed to your T.A as a PFD file by the announced deadline. ! Each assignment will contribute to 10% of your final grade ! 3- Seminar Presentations ! ! Attendance to the seminar presentations is mandatory! Students divided in groups have to present one research article twice.
    [Show full text]
  • Molecular Biology and Applied Genetics
    MOLECULAR BIOLOGY AND APPLIED GENETICS FOR Medical Laboratory Technology Students Upgraded Lecture Note Series Mohammed Awole Adem Jimma University MOLECULAR BIOLOGY AND APPLIED GENETICS For Medical Laboratory Technician Students Lecture Note Series Mohammed Awole Adem Upgraded - 2006 In collaboration with The Carter Center (EPHTI) and The Federal Democratic Republic of Ethiopia Ministry of Education and Ministry of Health Jimma University PREFACE The problem faced today in the learning and teaching of Applied Genetics and Molecular Biology for laboratory technologists in universities, colleges andhealth institutions primarily from the unavailability of textbooks that focus on the needs of Ethiopian students. This lecture note has been prepared with the primary aim of alleviating the problems encountered in the teaching of Medical Applied Genetics and Molecular Biology course and in minimizing discrepancies prevailing among the different teaching and training health institutions. It can also be used in teaching any introductory course on medical Applied Genetics and Molecular Biology and as a reference material. This lecture note is specifically designed for medical laboratory technologists, and includes only those areas of molecular cell biology and Applied Genetics relevant to degree-level understanding of modern laboratory technology. Since genetics is prerequisite course to molecular biology, the lecture note starts with Genetics i followed by Molecular Biology. It provides students with molecular background to enable them to understand and critically analyze recent advances in laboratory sciences. Finally, it contains a glossary, which summarizes important terminologies used in the text. Each chapter begins by specific learning objectives and at the end of each chapter review questions are also included.
    [Show full text]
  • Get App Journal Flyer
    IMPACT Indexed in: FACTOR PubMed 4.128 an Open Access Journal by MDPI The Hellenic Society Mikrobiokosmos (MBK) and Spanish Society for Nitrogen Fixation (SEFIN) are affiliated with Microorganisms IMPACT Indexed in: FACTOR PubMed 4.128 an Open Access Journal by MDPI Editor-in-Chief Message from the Editor-in-Chief Prof. Dr. Martin von Bergen “Microorganism” merges the idea of the very small with the idea of the evolving reproducing organism is a unifying principle for the discipline of microbiology. Our journal recognizes the broadly diverse yet connected nature of microorganisms and provides an advanced publishing forum for original articles from scientists involved in high-quality basic and applied research on any prokaryotic or eukaryotic microorganism, and for research on the ecology, genomics and evolution of microbial communities as well as that exploring cultured microorganisms in the laboratory. Author Benefits Open Access Unlimited and free access for readers No Copyright Constraints Retain copyright of your work and free use of your article Impact Factor 4.128 (2020 Journal Citation Reports®) Thorough and Rapid Peer-Review Coverage by Leading Indexing Services Science Citation Index Expanded - Web of Science (Clarivate Analytics), BIOSIS Previews (Clarivate Analytics), PubMed (NLM), Scopus (Elsevier) No Space Constraints, No Extra Space or Color Charges No restriction on the length of the papers, number of figures or colors Major Forum for Readers Interested in Diverse Aspects of Microorganisms Discounts on Article Processing Charges (APC) If you belong to an institute that participates with the MDPI Institutional Open Access Program (IOAP) Aims and Scope Microorganisms publishes original research, reviews, short communications, and commentaries.
    [Show full text]
  • Microbiology and Immunology 1
    Microbiology and Immunology 1 Microbiology and Programs Immunology Undergraduate Programs of Study Chair Major • Li Wu • Major in Microbiology (Bachelor of Science) Director, Undergraduate Studies Minor • Richard J. Roller • Minor in Microbiology Director, Graduate Studies • Timothy L. Yahr Graduate Programs of Study Undergraduate major: microbiology (B.S.) Majors Undergraduate minor: microbiology • Master of Science in Microbiology Graduate degrees: M.S. in microbiology; Ph.D. in microbiology • Doctor of Philosophy in Microbiology Faculty: https://medicine.uiowa.edu/microbiology/people/ primary-appointments Facilities Website: https://medicine.uiowa.edu/microbiology/ The Department of Microbiology and Immunology is Study in the Department of Microbiology and Immunology situated on the University of Iowa health sciences campus, is dedicated to the branch of biological sciences that where it shares the Bowen Science Building with the investigates the smallest living things: microbes that include Departments of Anatomy and Cell Biology, Biochemistry bacteria, archaea, fungi, algae, protozoa, and viruses. It and Molecular Biology, Molecular Physiology and Biophysics, is coupled with immunology that includes the study of the and Neuroscience and Pharmacology. Laboratory space and protective responses of higher organisms to disease-causing modern equipment are available for teaching and research. microbes and cancers, and mistakes in immune function. Microbiology and immunology often interact in humans at the microbiome, those microbes that live with humans on their Courses skin and mucosal surfaces, and yet must be restricted from causing diseases by the immune system. Microbiology and Immunology Microbiology and immunology are at the forefront of the Courses modern biological revolution. Microbes are experimental subjects of choice for examining genetic and biological MICR:2157 General Microbiology 3 s.h.
    [Show full text]
  • Top Peer Reviewed Journals – Microbiology
    Top Peer Reviewed Journals – Microbiology Presented to Iowa State University Presented by Thomson Reuters Microbiology The subject discipline for Microbiology is made of 5 narrow subject categories from the Web of Science. The 5 categories that make up Microbiology are: 1. Microbiology 4. Parasitology 2. Microscopy 5. Virology 3. Mycology The chart below provides an ordered view of the top peer reviewed journals within the 1st quartile for Microbiology based on Impact Factors (IF), three year averages and their quartile ranking. Journal 2009 IF 2010 IF 2011 IF Average IF NATURE REVIEWS MICROBIOLOGY 17.64 20.68 21.18 19.83 CLINICAL MICROBIOLOGY REVIEWS 14.69 13.5 16.12 14.77 Cell Host & Microbe 13.02 13.72 13.5 13.41 ANNUAL REVIEW OF MICROBIOLOGY 12.8 12.41 14.34 13.18 MICROBIOLOGY AND MOLECULAR 12.58 12.22 13.01 12.60 BIOLOGY REVIEWS FEMS MICROBIOLOGY REVIEWS 9.78 11.79 10.96 10.84 PLoS Pathogens 8.97 9.07 9.12 9.05 ADVANCES IN MICROBIAL PHYSIOLOGY 5.75 8.55 9.87 8.06 CURRENT OPINION IN MICROBIOLOGY 7.86 7.71 7.92 7.83 TRENDS IN MICROBIOLOGY 6.89 7.5 7.91 7.43 REVIEWS IN MEDICAL VIROLOGY 7.44 5.6 7.2 6.75 ISME Journal 6.39 6.15 7.37 6.64 CRITICAL REVIEWS IN MICROBIOLOGY 5.34 6.27 5.81 CELLULAR MICROBIOLOGY 5.72 5.62 5.45 5.60 Advances in Parasitology 6.23 4.39 5.31 mBio 5.31 5.31 Retrovirology 4.1 5.23 6.47 5.27 JOURNAL OF VIROLOGY 5.15 5.18 5.4 5.24 MOLECULAR MICROBIOLOGY 5.36 4.81 5.01 5.06 TRENDS IN PARASITOLOGY 4.29 4.9 5.14 4.78 ADVANCES IN VIRUS RESEARCH 5.52 4.83 3.97 4.77 ANTIMICROBIAL AGENTS AND 4.8 4.67 4.84 4.77 CHEMOTHERAPY
    [Show full text]
  • Department of Microbiology and Immunology University of Louisville School of Medicine
    Department of Microbiology and Immunology University of Louisville School of Medicine Faculty Position in Virology The School of Medicine at the University of Louisville invites applications for a tenure-track position in the Department of Microbiology and Immunology at the Assistant, Associate, or Full Professor level. The ideal candidate will have an active and productive research program in the area of virus-host interactions. Both BSL-3 and ABSL-3 research can be accommodated by the university’s state-of-the-art facilities. The Department of Microbiology and Immunology is strongly research-oriented, with 22 primary faculty members maintaining major programs in bacterial pathogenesis, cellular microbiology, immunology, and virology. The newly recruited faculty member will have laboratory space in the new Clinical Translational Research Building (CTRB) that is fully equipped for research in molecular and cellular biology, including live cell imaging, genomics, flow cytometry and state of the art animal housing with whole animal imaging capability. For more details on faculty and research programs, please visit: http://louisville.edu/medicine/departments/microbiology. The U of L School of Medicine provides an excellent research environment and the majority of the departmental faculty are also members of either the Center for Predictive Medicine for Emerging Infectious Diseases and Biodefense (CPM), the Institute for Cellular Therapeutics (ICT) or the James Graham Brown Cancer Center (JGBCC). These active academic research centers offer a wide range of facilities as well as collaborative research opportunities. The CPM manages the newly constructed 45 million dollar Regional Biocontainment Laboratory (RBL) that houses advanced instrumentation for the study of pathogens and infectious diseases.
    [Show full text]
  • Micropropagation, Genetic Engineering, and Molecular Biology Expression Vectors Containing the Gene(S) and Promoter(S) of Populus
    This file was created by scanning the printed publication. Errors identified by the software have been corrected; however, some errors may remain. Chapter 11 Growth and Development Alteration in Transgenic Populus: Status and Potential Applications1 Bjorn Sundberg, Hannele Tuominen, Ove Nilsson, Thomas Moritz, c. H. Anthony Little, Goran Sandberg, and Olof Olsson Introduction Using Transgenic Populus to Study Growth and Development With the development of gene-transfer techniques appli­ cable to forest tree species, genetic engineering is becoming in Woody Species an alternative to traditional tree breeding. To date, routine transformation methods for several hardwood species, par­ The best model system for understanding the genetic ticularly Populus and Eucalyptus, have been established and and physiological control of tree growth and wood for­ promising advances have occurred in the development ~f mation is a perennial species containing a vascular cam­ transformation protocols for conifers (Olarest et al. 1996; Ellis bium, which is the meristem that produces secondary et al. 1996; Jouanin et al. 1993; Walters et al. 1995). Rapid xylem and phloem. Presently, Populus is the preferred tree­ progress in transformation technology makes it possible to model system because it has several useful fea.tures. develop genetic engineering tools that modify economically Populus has a small genome, approximately 5 x lOS base tractable parameters related to growth and yield in tree spe­ pairs (bp ), which encourages molecular mapping, library cies. Such work will also increase our understanding of ge­ screening, and rescue cloning. Saturated genetic maps are netic and physiological regulation of growth and already constructed for several Populus spp. (Bradshaw et development in woody species.
    [Show full text]
  • Glossary/Index
    Glossary 03/08/2004 9:58 AM Page 119 GLOSSARY/INDEX The numbers after each term represent the chapter in which it first appears. additive 2 allele 2 When an allele’s contribution to the variation in a One of two or more alternative forms of a gene; a single phenotype is separately measurable; the independent allele for each gene is inherited separately from each effects of alleles “add up.” Antonym of nonadditive. parent. ADHD/ADD 6 Alzheimer’s disease 5 Attention Deficit Hyperactivity Disorder/Attention A medical disorder causing the loss of memory, rea- Deficit Disorder. Neurobehavioral disorders character- soning, and language abilities. Protein residues called ized by an attention span or ability to concentrate that is plaques and tangles build up and interfere with brain less than expected for a person's age. With ADHD, there function. This disorder usually first appears in persons also is age-inappropriate hyperactivity, impulsive over age sixty-five. Compare to early-onset Alzheimer’s. behavior or lack of inhibition. There are several types of ADHD: a predominantly inattentive subtype, a predomi- amino acids 2 nantly hyperactive-impulsive subtype, and a combined Molecules that are combined to form proteins. subtype. The condition can be cognitive alone or both The sequence of amino acids in a protein, and hence pro- cognitive and behavioral. tein function, is determined by the genetic code. adoption study 4 amnesia 5 A type of research focused on families that include one Loss of memory, temporary or permanent, that can result or more children raised by persons other than their from brain injury, illness, or trauma.
    [Show full text]