sign in sign up
<<
Home , Cellular microbiology, Microbial genetics, Microbiological Research, Microbiology (journal), Molecular genetics

and Molecular 1

For certification and completion of the BS degree, students will take MICROBIOLOGY AND one year of clinical internship in program accredited by the National Accrediting Agency for Clinical Laboratory Science (NAACLS) and affiliated with Oklahoma State University. Students have the options of the following hospitals/programs: Comanche County Memorial Hospital, Microbiology/ and Molecular Lawton, OK; St. Francis Hospital, Tulsa, OK; Mercy Hospital, Ada, OK; Mercy Hospital, Ardmore, OK. Microbiology is the hands-on study of , , fungi and algae and their many relationships to humans, animals, plants and the Medical Laboratory Science is unique in allowing students to enter environment. Cell and bridges the fields of chemistry, the health profession directly after obtaining a BS degree. Clinical and biology as it seeks to understand life and cellular laboratory scientists comprise the third-largest segment of the healthcare processes at the molecular level. Microbiologists apply their knowledge professions and are an important member of the healthcare team, to infectious diseases and pathogenic mechanisms; food production working alongside doctors and nurses. Students who complete and preservation, industrial fermentations which produce chemicals, Microbiology/Cell and Molecular Biology with the MLS option enjoy a drugs, antibiotics, alcoholic beverages and various food products; 100% employment rate upon graduation. biodegradation of toxic chemicals and other materials present in the environment; insect ; the exciting and expanding field of Courses which endeavors to utilize living organisms to solve 5102 Molecular Genetics important problems in , agriculture, and environmental science; Prerequisites: BIOC 3653 or MICR 3033 and one course in genetics or infectious diseases; and public health and sanitation. consent of instructor. Microbes live in every imaginable . They generate two-thirds of Description: An introduction to molecular genetics on the graduate level. the oxygen in our atmosphere, drive the geochemical cycles that make Credit hours: 2 life on Earth sustainable and are the basis of every food web. As model Contact hours: Lecture: 2 Contact: 2 organisms used for basic research, microbes have contributed more Levels: Graduate than any other organisms to the current knowledge of genetics at the Schedule types: Lecture molecular level and . Department/School: Graduate College MICR 1211 First Year Microbiology Laboratory Experience In contrast to the enormous benefits derived from some microbes, other Prerequisites: MCMB major and concurrent enrollment in A&S 1111. and viruses are the causative agents of infectious Description: This laboratory course is designed for First Year majors disease and hence have a devastating impact on humanity. These to experience microbiology in parallel with A&S 1111. Students will are the subjects of research into the mechanisms of apply pure culture technique to obtain and characterize environmental , with the ultimate goal of combating or preventing diseases. isolates. Students also will learn light skills, anaerobic culture Departmental courses are designed to provide comprehensive training technique, and molecular biology skills. and the skills required for working with microorganisms in a professional Credit hours: 1 setting, as well as a broad understanding of all aspects of microbial Contact hours: Lab: 2 Contact: 2 life. The lecture courses are taught by tenured faculty members and the Levels: Undergraduate laboratory courses are designed to integrate classroom learning with Schedule types: Lab hands-on research experience. Department/School: Microbiology & Mol Gen MICR 1513 Inquiry-Based Biology Opportunities for employment exist at all scholarly levels, in many local, Description: Directed inquiry and hands-on study of biological principles. state and national agencies and industry. The record for employment Restricted to elementary education majors or related fields as model of microbiologists has been excellent for many years and with the course to learn and teach science. increased interest in biotechnology, medicine and the human , Credit hours: 3 employment opportunities look even brighter for the future. Contact hours: Lecture: 1 Lab: 4 Contact: 5 Levels: Undergraduate Microbiology is the strongest possible foundation for students who Schedule types: Lab, Lecture, Combined lecture and lab wish to go to medical, dental, veterinary or graduate schools. We take Department/School: Microbiology & Mol Gen pride in offering research and internship opportunities that prepare students for careers in the . Our graduates find jobs MICR 2123 Introduction to Microbiology in medicine, health care, medical laboratories, teaching, research, industry Prerequisites: Grade of "C" or better in BIOL 1114 and either CHEM 1215 and government. or CHEM 1314 with a grade of "C" or better or concurrent enrollment in one. Medical Laboratory Science Option Description: General principles of the biology of microorganisms, This option is designed to give students the broad general education and including bacteria, viruses, algae, fungi, and . Course the technical skills that are required for a successful career in medical previously offered as MICR 2125. laboratory science (MLS). The minimum requirement for the BS degree Credit hours: 3 in Microbiology/Cell and Molecular Biology with the (MLS) option is Contact hours: Lecture: 3 Contact: 3 three years of university work that includes general chemistry, organic Levels: Undergraduate chemistry, biochemistry, , genetics, & , Schedule types: Lecture physics, upper-division courses in microbiology, and one year of clinical Department/School: Microbiology & Mol Gen laboratory education (internship). 2 Microbiology and Molecular Genetics

MICR 2132 Introduction to Microbiology Laboratory MICR 3154 Food Microbiology Prerequisites: MICR 2123 or concurrent enrollment. Prerequisites: Minimum grade of "C" in (MICR 2123 and MICR 2132) and Description: Laboratory safety, aseptic technique, microscopy, staining (CHEM 3013 or CHEM 3053). and culture techniques, collection of microbial samples, isolation and Description: Relationship of microorganisms to food manufacture and identification of microorganisms, microbial growth and basic principles preservation, to food spoilage and microbial food poisoning and to of , environmental microbiology, other discipline specific various aspects of primary food production. Same course as FDSC 3154. laboratory skills. Course previously offered as ANSI 3154. Credit hours: 2 Credit hours: 4 Contact hours: Lab: 4 Contact: 4 Contact hours: Lecture: 2 Lab: 4 Contact: 6 Levels: Undergraduate Levels: Undergraduate Schedule types: Lab Schedule types: Lab, Lecture, Combined lecture and lab Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen MICR 2890 Honors Experience in Microbiology MICR 3223 Advanced Microbiology Prerequisites: Honors Program participation and concurrent enrollment in Prerequisites: Concurrent enrollment or completion of CHEM 3013 or a designated MICR course. CHEM 3053 and minimum grade of "C" in MICR 2123 and MICR 2132. Description: A supplemental Honors experience in Microbiology to Description: Subcellular structure and of microorganisms. partner concurrently with designated MICR 2123 and/or MICR 2132 Synthesis, translocation, and metabolism of cellular macromolecular course(s). This course adds a different intellectual dimension to the constituents. Substrate transport and metabolism. Course previously designated course(s). offered as MICR 3224 and MICR 4224. Credit hours: 1 Credit hours: 3 Contact hours: Lecture: 1 Contact: 1 Contact hours: Lecture: 3 Contact: 3 Levels: Undergraduate Levels: Undergraduate Schedule types: Lecture Schedule types: Lecture Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen General Education and other Course Attributes: Honors Credit MICR 3233 Foundations of Cancer Biology MICR 3033 Cell and Molecular Biology Prerequisites: Two of the following four courses: MICR 2123; CHEM 3053; Prerequisites: MICR 2123 and MICR 2132 with "C" or better or BOT 1404 MICR 3033; BIOL 3023. or ZOOL 1604 and CHEM 1225 or CHEM 1515 or equivalent with a grade Description: The foundations of cancer biology will be presented in of "C" or better. a systematic and generally accessible manner. Developments in the Description: The cell concept and cell morphology, cell macromolecules, understanding, treatment and prevention of cancer will be used to organelles, , energetics, movement of water and materials illustrate both setbacks and victories in applying the scientific method across membranes, influence of external environment, cellular synthesis, to a biological process. The methods and models used to understand growth and maintenance, control and integration of function, replication, cancer, and the evidence for and assumptions made in these approaches differentiation, origin, and of cells. Course previously offered as will be discussed. Students will select a topic related to cancer biology CLML 3014, BIOL 3014, and BISC 3014. and will write a scientific essay on this topic. Credit hours: 3 Credit hours: 3 Contact hours: Lecture: 3 Contact: 3 Contact hours: Lecture: 3 Contact: 3 Levels: Undergraduate Levels: Undergraduate Schedule types: Lecture Schedule types: Lecture Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen MICR 3103 Microbes: Friends or Foes (N) MICR 3253 Immunology Description: Explores the impact of microorganisms on human life, the Prerequisites: MICR 2123 and MICR 2132 and MICR 3033 or BIOC 3653 or environment, and world history. This course is designed for non-science BIOC 3713. majors. Description: Vertebrate ’s ability to defend itself against foreign Credit hours: 3 intrusion. Chemistry and biology of the acquired immune response. Contact hours: Lecture: 3 Contact: 3 Course previously offered as MICR 3254 and CLML 3254. Levels: Undergraduate Credit hours: 3 Schedule types: Lecture Contact hours: Lecture: 3 Contact: 3 Department/School: Microbiology & Mol Gen Levels: Undergraduate General Education and other Course Attributes: Natural Sciences Schedule types: Lecture MICR 3143 Medical Department/School: Microbiology & Mol Gen Prerequisites: MICR 2123 and MICR 2132 with a grade of "C" or better. Description: Examination of fungi as animal pathogens; laboratory techniques used in the identification of human and animal pathogens, and differentiation from common contaminants. Credit hours: 3 Contact hours: Lecture: 1 Lab: 4 Contact: 5 Levels: Undergraduate Schedule types: Lab, Lecture, Combined lecture and lab Department/School: Microbiology & Mol Gen Microbiology and Molecular Genetics 3

MICR 3333 Molecular Life Science Writing MICR 4003 Brewing Microbiology (N) Prerequisites: BIOL 1114. Description: Brewing Microbiology is about the science behind beer Description: Students will gain hands-on experience in technical writing brewing. Students will learn about the microbiology of (including and critical reading of scientific texts. Students will write three different growth, metabolism, aseptic technique and contamination), biology of documents and will critically review similar texts written by other grain, biochemistry of malted barley, chemistry of water, preservative students enrolled in the course. The topics for these manuscripts will of hops, and the human physiology of taste and smell. There are be selected by the students, but should be in the general area of the no prerequisites for this course, although high school or freshman level molecular life sciences. Students will receive instructions on how to write, biology and chemistry is helpful. revise, and review these documents. Credit hours: 3 Credit hours: 3 Contact hours: Lecture: 3 Contact: 3 Contact hours: Lecture: 3 Contact: 3 Levels: Undergraduate Levels: Undergraduate Schedule types: Lecture Schedule types: Lecture Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen General Education and other Course Attributes: Natural Sciences MICR 3890 Advanced Honors Experience in Microbiology MICR 4012 Molecular Microbiology Laboratory I Prerequisites: Honors Program participation and concurrent enrollment in Prerequisites: MICR 3033 or MICR 3223. a designated MICR course. Description: Emphasis on good laboratory practices in microbiology Description: A supplemental Honors experience in microbiology to and molecular biology; isolation and enumeration of microorganisms; partner concurrently with designated upper-division MICR course(s). physiological, biochemical, and molecular characterization of aerobic This course adds a different intellectual dimension to the designated and anaerobic microorganisms. May not be used for degree credit with course(s). MICR 5012. Course previously offered as CLML 4012. Credit hours: 1 Credit hours: 2 Contact hours: Lecture: 1 Contact: 1 Contact hours: Lab: 4 Contact: 4 Levels: Undergraduate Levels: Undergraduate Schedule types: Lecture Schedule types: Lab Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen General Education and other Course Attributes: Honors Credit MICR 4013 Microbial Physiology & MICR 4000 Honors in Microbiology Prerequisites: Concurrent enrollment or completion of MICR 3223 and Prerequisites: Consent of departmental honors committee. minimum grade of "C" in CHEM 3013 or CHEM 3053. Description: Supervised study and research in microbiology. Offered for Description: Fundamentals of microbial physiology, ecology and variable credit, 1-4 credit hours, maximum of 4 credit hours. genetics of microbial populations under various redox conditions. Credit hours: 1-4 Basics of genomics and . Microbial origin and evolution. Contact hours: Contact: 1-4 Other: 1-4 Microbial diversity and function. Population interactions, competition Levels: Undergraduate and ecosystem stability. Metabolic activities in natural and managed Schedule types: Independent Study systems. Modern molecular tools in microbe identification and Department/School: Microbiology & Mol Gen evolutionary phylogeny. May not be used for degree credit with General Education and other Course Attributes: Honors Credit MICR 5013. MICR 4001 Professional Transitions in Microbiology and Cell and Credit hours: 3 Molecular Biology Contact hours: Lecture: 3 Contact: 3 Prerequisites: MICR 2123 or MICR 2132. Levels: Undergraduate Description: Understanding major areas and employment activities in Schedule types: Lecture microbiology, and molecular biology fields. Evaluating and Department/School: Microbiology & Mol Gen understanding scientific and professional literature, and making the MICR 4023 in Human Health and the Environment transition from undergraduate education to postgraduate education or Prerequisites: MICR 2123, MICR 2132, and MICR 3033. employment. Description: This course covers the changing landscape in the molecular Credit hours: 1 diversity of microbial communities, their interactions with biotic and Contact hours: Lecture: 1 Contact: 1 abiotic entities, and how changes in microbiomes impact the health Levels: Undergraduate of living organisms and the environment. The main topics of this Schedule types: Lecture course include: microbes and microbial interactions; and Department/School: Microbiology & Mol Gen metagenomes; microbiome structure and function (alpha and beta diversity, phylogenetic trees); human microbiomes (gut, skin, oral) and their role in health; the microbiomes of soil, water and sediments; and the role of microbiomes in ecosystem function. Environmental microbiome effects on the human microbiome. May not be used for degree credit with MICRO 5023. Credit hours: 3 Contact hours: Lecture: 3 Contact: 3 Levels: Undergraduate Schedule types: Lecture Department/School: Microbiology & Mol Gen 4 Microbiology and Molecular Genetics

MICR 4052 Pathogenic Microbiology Lab MICR 4125 Clinical Chemistry I Prerequisites: MICR 2123 and MICR 2132 with a grade of "C" or better. Prerequisites: Concurrent internship in affiliated hospital and all Description: Overview of laboratory approaches and techniques for degree requirements for BS in microbiology except for 30 hours clinical the study, characterization, and identification of bacteria involved in laboratory science. pathogenesis. Description: The theory and laboratory methodology of analytical Credit hours: 2 biochemistry, clinical microscopy, routine and special procedures, and Contact hours: Lab: 4 Contact: 4 medical significance. Course previously offered as CLLS 4125 and MTCL Levels: Undergraduate 4125. Schedule types: Lab Credit hours: 5 Department/School: Microbiology & Mol Gen Contact hours: Contact: 10 Other: 10 MICR 4053 Pathogenic Microbiology Levels: Undergraduate Prerequisites: MICR 2123 and MICR 2132 with a grade of "C" or better. Schedule types: Independent Study Description: Survey of pathogenic bacteria and the diseases they cause Department/School: Microbiology & Mol Gen as they relate to humans and animals. Morphology, physiology, and MICR 4153 Emerging Infectious Agents (N) pathogenic mechanisms of a specific bacterial pathogens. May not be Description: Overview of emerging infectious diseases with in-depth used for degree credit with MICR 5053. Course previously offered as analysis of epidemics, pandemics, the associated with MICR 4134 and MICR 3134. outbreaks and disease specific control measures. Credit hours: 3 Credit hours: 3 Contact hours: Lecture: 3 Contact: 3 Contact hours: Lecture: 3 Contact: 3 Levels: Undergraduate Levels: Undergraduate Schedule types: Lecture Schedule types: Lecture Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen MICR 4112 Molecular Microbiology Capstone General Education and other Course Attributes: Natural Sciences Prerequisites: MICR 4012 with a grade of "C" or better. MICR 4163 Foundations of Cellular Life Description: Continuation of MICR 4012. Molecular characterization Prerequisites: MICR 3033 or permission from instructor. of prokaryotic and eukaryotic microorganisms utilizing nucleic acids, Description: This class will provide an in-depth introduction into , cell fractionation, cytology, and antigen-antibody reactions. fundamental principles that apply to any and will provide Same course as MICR 5112. an intellectual framework to understand all cells. The fundamentals Credit hours: 2 discussed will be illustrated through a combination of classical and Contact hours: Lab: 4 Contact: 4 recent scientific breakthroughs. It will provide a solid, deep foundation Levels: Undergraduate for a successful academic career in microbiology. May not be used for Schedule types: Lab degree credit with MICR 5163. Department/School: Microbiology & Mol Gen Credit hours: 3 MICR 4117 Clinical Microbiology Contact hours: Lecture: 3 Contact: 3 Prerequisites: Concurrent internship in affiliated hospital and all degree Levels: Undergraduate requirements for BS in microbiology except 30 hours clinical laboratory Schedule types: Lecture science. Department/School: Microbiology & Mol Gen Description: The theory and laboratory study of pathogenic bacteria, MICR 4203 viruses, rickettsiae, fungi, and parasites. Includes isolation, identification, Prerequisites: MICR 3033 or BIOC 3653 or equivalent. antimicrobial susceptibility testing, and medical significance. Course Description: Fundamental concepts of biological sequence information previously offered as CLLS 4117 and MTCL 4117. and inferential techniques to assign structure, function, and evolutionary Credit hours: 7 relationship among and proteins. No prior programming necessary, Contact hours: Contact: 14 Other: 14 but familiarity with computers assumed. No credit for students with Levels: Undergraduate credit in MICR 5203. Schedule types: Independent Study Credit hours: 3 Department/School: Microbiology & Mol Gen Contact hours: Lecture: 3 Contact: 3 MICR 4123 Levels: Undergraduate Prerequisites: MICR 2123, MICR 2132, BIOL 3023, CHEM 3015 or Schedule types: Lecture CHEM 3053; Co-requisite(s): MICR 3223. Department/School: Microbiology & Mol Gen Description: The properties of macromolecules, from the structure of proteins and nucleic acids to molecular mechanisms of DNA replication and recombination, , synthesis, and gene regulation. Gene transfer mechanisms in bacteria and their viruses. Fundamentals of recombinant DNA technology. No credit for students with credit in MICR 5123. Credit hours: 3 Contact hours: Lecture: 3 Contact: 3 Levels: Undergraduate Schedule types: Lecture Department/School: Microbiology & Mol Gen Microbiology and Molecular Genetics 5

MICR 4233 Advanced Cell and Molecular Biology MICR 4263 : from Genes to Genomes Prerequisites: MICR 3033 with a grade of "C" or better. Prerequisites: MICR 3033 with a grade of "C" or better. Description: Advanced topics in cell and molecular biology including Description: Integration of genetics and genomics principles, the basic regulatory mechanisms of , protein function, cell processes of gene transmission, molecular biology of gene expression structure and organization, cell division, and development. May not be and evolutionary genetics by gaining social and historical context in used for degree credit with MICR 5233. Course previously offered as which genetics are developed. Participants are expected to comprehend CLML 4113. the dramatic change in our understanding of genetics and the role such Credit hours: 3 information has in our view of disability and disease. May not be used for Contact hours: Lecture: 3 Contact: 3 degree credit with MICR 5263. Course previously offered as CLML 4263 Levels: Undergraduate and CLML 4264. Schedule types: Lecture Credit hours: 3 Department/School: Microbiology & Mol Gen Contact hours: Lecture: 1 Lab: 4 Contact: 5 MICR 4236 Clinical Hematology Levels: Undergraduate Prerequisites: Concurrent internship in affiliated hospital and all degree Schedule types: Lab, Lecture, Combined lecture and lab requirements for BS in microbiology except for 30 hours of clinical Department/School: Microbiology & Mol Gen laboratory science. MICR 4323 Cellular Energy Metabolism Description: Systematized study of diseases, cell maturation and Prerequisites: MICR 3033 or BIOC 3653. function, principles of hemostasis; methodology used in routine and Description: An exploration of the principals and mechanisms of energy special hematology studies; and correlation of hematological findings utilization and transformation in animals, plants, and microbial systems. with physiological conditions. Course previously offered as CLLS 4236 The course covers a range of topics from basic molecular mechanisms and MTCL 4236. to recent advances in understanding energy flow in whole organisms. It Credit hours: 6 includes new insights into the nanomachines involved in cell movement Contact hours: Contact: 12 Other: 12 as well current -enabled approaches to understanding cellular Levels: Undergraduate energy metabolism. May not be used for degree credit with MICR 5323. Schedule types: Independent Study Credit hours: 3 Department/School: Microbiology & Mol Gen Contact hours: Lecture: 3 Contact: 3 MICR 4246 Clinical Immunology Levels: Undergraduate Prerequisites: Concurrent internship in affiliated hospital and all Schedule types: Lecture degree requirements for BS in microbiology except for 30 hours clinical Department/School: Microbiology & Mol Gen laboratory science. MICR 4325 Clinical Chemistry II Description: Immunologic responses and procedures used in serological Prerequisites: Concurrent internship in affiliated hospital and all determinations; immunohematology, fundamentals of antigen- degree requirements for BS in microbiology except for 30 hours clinical antibody reactions, blood groups and types, compatibility testing, blood laboratory science. components, and the lab methods used as they relate to the medical Description: The theory and laboratory methodology of analytical significance of immunology and infectious diseases. Course previously biochemistry, instrumentation, lab mathematics, routine and special offered as CLLS 4246 and MTCL 4246. procedures and medical significance. Course previously offered as CLLS Credit hours: 6 4325 and MTCL 4325. Contact hours: Contact: 12 Other: 12 Credit hours: 5 Levels: Undergraduate Contact hours: Contact: 10 Other: 10 Schedule types: Independent Study Levels: Undergraduate Department/School: Microbiology & Mol Gen Schedule types: Independent Study MICR 4253 Concepts in Department/School: Microbiology & Mol Gen Prerequisites: BIOL 3023. MICR 4351 Topics in Clinical Laboratory Science Description: Application of genetic principles in the study of human Prerequisites: Concurrent internship in affiliated hospital and all diseases, including the inheritance, molecular mechanisms, detection, degree requirements for BS in microbiology except for 30 hours clinical characterization, and discovery of human genes. No credit for students laboratory science. with credit in MICR 5253. Course previously offered as CLML 4253. Description: Principles and practices of the medical laboratory including Credit hours: 3 basic management, quality assurance, education methodology, computer Contact hours: Lecture: 3 Contact: 3 applications, laboratory safety, and special projects in selected areas. Levels: Undergraduate Course previously offered as CLLS 4351 and MTCL 4351. Schedule types: Lecture Credit hours: 1 Department/School: Microbiology & Mol Gen Contact hours: Contact: 1 Other: 1 Levels: Undergraduate Schedule types: Independent Study Department/School: Microbiology & Mol Gen 6 Microbiology and Molecular Genetics

MICR 4423 Antibiotics and Antibiotic Resistance MICR 4990 Special Problems Prerequisites: MICR 2123. Prerequisites: Consent of instructor. Description: This course begins with a basic history of antibiotics, Description: Investigations in the field of microbiology. Offered for including their discovery and industrial development. It covers the major variable credit, 1-3 credit hours, maximum of 18 credit hours. classes of antibiotics, their structures and mechanisms of action, and Credit hours: 1-3 the mechanisms by which bacteria become resistant to antibiotics. Contact hours: Contact: 1-3 Other: 1-3 Also covered are industrial and commercial considerations, antibiotic Levels: Undergraduate stewardship, current challenges, and future prospects for antibiotic Schedule types: Independent Study discovery and use. Same course as MICR 5423. Department/School: Microbiology & Mol Gen Credit hours: 3 MICR 4993 Senior Honors Project Contact hours: Lecture: 3 Contact: 3 Prerequisites: Departmental invitation, senior standing, Honors Program Levels: Undergraduate participation. Schedule types: Lecture Description: A research project under the direction of a faculty member Department/School: Microbiology & Mol Gen resulting in a written report to be judged by a second faculty member as MICR 4524 Biological Laboratory Instrumentation well. Required for graduation with departmental honors in microbiology. Prerequisites: CHEM 1515 or equivalent and PBIO 1404 or MICR 2123 or Credit hours: 3 BIOL 1604 or equivalents or consent of instructor. Contact hours: Contact: 3 Other: 3 Description: Lecture and laboratory course in biological instrumentation Levels: Undergraduate use, theory, experimental design, maintenance, and troubleshooting. Schedule types: Independent Study Topics include liquid handling systems, pH/ISE meters, , Department/School: Microbiology & Mol Gen microcontrollers, spectrophotometers, centrifuges, chromatography, General Education and other Course Attributes: Honors Credit thermocyclers, and DNA sequencers. May not be used for degree credit MICR 5000 Thesis with BIOL 5524, MICR 5524, PBIO 5524. Same course as BIOL 4524 and Prerequisites: Consent of major professor. PBIO 4524. Description: A student studying for the M.S. degree enrolls in this course Credit hours: 4 for six hours credit. Offered for variable credit, 2-6 credit hours, maximum Contact hours: Lecture: 2 Lab: 4 Contact: 6 of 6 credit hours. Levels: Undergraduate Credit hours: 2-6 Schedule types: Lab, Lecture, Combined lecture and lab Contact hours: Contact: 2-6 Other: 2-6 Department/School: Microbiology & Mol Gen Levels: Graduate MICR 4531 Schedule types: Independent Study Prerequisites: CHEM 3053, MICR 3112, MICR 3153. Department/School: Microbiology & Mol Gen Description: Chemistry explains many properties of biological MICR 5002 Professionalism for the Microbiologist macromolecules and also provides research tools to study these Prerequisites: Microbiology graduate student or permission of instructor. molecules. This course will examine how both of these aspects help Description: Introduces the microbiology graduate student to the explain the molecular processes at the basis of life, and will cover (1) standards of the microbiology professional and to basic skills in basic knowledge of chemistry needed to understand life, (2) chemical communication and data retrieval needed by all microbiologists. It is reactions as they occur in the cell, (3) chemical methods that are valuable required of all and limited to MS and PhD students in Microbiology & to research in the life sciences. Molecular Genetics. Course previously offered as MICR 5001. Credit hours: 1 Credit hours: 2 Contact hours: Lecture: 1 Contact: 1 Contact hours: Lecture: 2 Contact: 2 Levels: Undergraduate Levels: Graduate Schedule types: Lecture Schedule types: Lecture Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen MICR 4543 Microbial Genomics and Bioinformatics MICR 5012 Molecular Microbiology Laboratory I Prerequisites: MICR 2123; MICR 3033 or MICR 3223 or equivalents. Prerequisites: MICR 3223, MICR 4233. Description: Basic approaches and strategies for microbial genome Description: Emphasis on good laboratory practices in microbiology analysis, and hands-on training on the subject. May not be used for and molecular biology; isolation and enumeration of microorganisms; degree credit with MICR 5543. physiological, biochemical, and molecular characterization of aerobic and Credit hours: 3 anaerobic microorganisms. Must be taken in conjunction with MICR 5112 Contact hours: Lecture: 3 Contact: 3 the following semester. No credit for students with credit in MICR 4012. Levels: Undergraduate Credit hours: 2 Schedule types: Lecture Contact hours: Lab: 4 Contact: 4 Department/School: Microbiology & Mol Gen Levels: Graduate Schedule types: Lab Department/School: Microbiology & Mol Gen Microbiology and Molecular Genetics 7

MICR 5013 Microbial Physiology and Ecology MICR 5112 Molecular Microbiology Capstone Prerequisites: Concurrent enrollment or completion of MICR 3223 and Prerequisites: MICR 5012. minimum grade of "C" in CHEM 3013 or CHEM 3053. Description: Continuation of MICR 5012. Molecular characterization Description: Fundamentals of microbial physiology, ecology and of prokaryotic and eukaryotic microorganisms utilizing nucleic acids, genetics of microbial populations under various redox conditions. proteins, cell fractionation, cytology, and antigen-antibody reactions. No Basics of genomics and proteomics. Microbial origin and evolution. credit for students with credit in MICR 4112. Microbial diversity and function. Population interactions, competition Credit hours: 2 and ecosystem stability. Metabolic activities in natural and managed Contact hours: Lab: 4 Contact: 4 systems. Modern molecular tools in microbe identification and Levels: Graduate evolutionary phylogeny. May not be used for degree credit with Schedule types: Lab MICR 4013. Department/School: Microbiology & Mol Gen Credit hours: 3 MICR 5113 Advanced Immunology Contact hours: Lecture: 3 Contact: 3 Description: Advanced studies with emphasis on the regulation of Levels: Graduate vertebrate immune responses. Schedule types: Lecture Credit hours: 3 Department/School: Microbiology & Mol Gen Contact hours: Lecture: 3 Contact: 3 MICR 5023 Microbiomes in Human Health and the Environment Levels: Graduate Description: This course covers the changing landscape in the molecular Schedule types: Lecture diversity of microbial communities, their interactions with biotic and Department/School: Microbiology & Mol Gen abiotic entities, and how changes in microbiomes impact the health MICR 5123 Virology of living organisms and the environment. The main topics of this Prerequisites: MICR 3033 or BIOC 3653, BIOL 3023. Co-requisite(s): course include: microbes and microbial interactions; genomes and MICR 3223. metagenomes; microbiome structure and function (alpha and beta Description: -host interactions including structure-function of diversity, phylogenetic trees); human microbiomes (gut, skin, oral) and animal, plant, and bacterial viruses. Discussion of the molecular biology their role in health; the microbiomes of soil, water, and sediments; and the of virus and development. No credit for students with credit in role of microbiomes in ecosystem function. Environmental mircobiome MICR 4123. effects on the human microbiome. May not be used for degree credit with Credit hours: 3 MICR 4023. Contact hours: Lecture: 3 Contact: 3 Credit hours: 3 Levels: Graduate Contact hours: Lecture: 3 Contact: 3 Schedule types: Lecture Levels: Graduate Department/School: Microbiology & Mol Gen Schedule types: Lecture Department/School: Microbiology & Mol Gen MICR 5142 Techniques in Molecular Biology Prerequisites: Consent of instructor. MICR 5052 Techniques In Molecular Biolog Description: Comprehensive laboratory course in research techniques Prerequisites: Graduate student and permission of instructor. involving and molecular biology. Course previously Description: Provides the basic skills for scientific thinking and analysis offered as MICR 4142. in molecular microbiological research. Credit hours: 2 Credit hours: 2 Contact hours: Lab: 4 Contact: 4 Contact hours: Lecture: 1 Lab: 2 Contact: 3 Levels: Graduate Levels: Graduate Schedule types: Lab Schedule types: Lab, Lecture, Combined lecture and lab Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen MICR 5153 Emerging Infectious Agents MICR 5053 Pathogenic Microbiology Prerequisites: MICR 4123 or MICR 4134 or consent of instructor. Prerequisites: MICR 2123 and MICR 2132. Co-requisite(s): MICR 3223. Description: An in-depth discussion of the importance of emerging Description: Survey of pathogenic bacteria and the diseases they cause infectious agents, the molecular basis for their emergence, and the broad as they relate to humans and animals. Morphology, physiology, and spectrum of host-microbe interactions favoring the evolution of new pathogenic mechanisms of specific bacterial pathogens. May not be infectious agents. used for degree credit with MICR 4053. Course previously offered as Credit hours: 3 MICR 5134. Contact hours: Lecture: 3 Contact: 3 Credit hours: 3 Levels: Graduate Contact hours: Lecture: 3 Contact: 3 Schedule types: Lecture Levels: Graduate Department/School: Microbiology & Mol Gen Schedule types: Lecture Department/School: Microbiology & Mol Gen 8 Microbiology and Molecular Genetics

MICR 5160 Seminar MICR 5263 Microbial Genetics: from Genes to Genomes Prerequisites: Consent of instructor. Description: Integration of genetics and genomics principles, the basic Description: Required of and limited to all MS and PhD students majoring processes of gene transmission, molecular biology of gene expression in microbiology, cell and molecular biology. Offered for fixed credit, 1 and evolutionary genetics by gaining social and historical context in credit hour, maximum of 2 credit hours. which genetics are developed. Participants are expected to comprehend Credit hours: 1 the dramatic change in our understanding of genetics and the role such Contact hours: Contact: 1 Other: 1 information has in our view of disability and disease. May not be used for Levels: Graduate degree credit with MICR 4263. Schedule types: Independent Study Credit hours: 3 Department/School: Microbiology & Mol Gen Contact hours: Lecture: 1 Lab: 4 Contact: 5 MICR 5163 Foundations of Cellular Life Levels: Graduate Prerequisites: OSU graduate student or permission of instructor. Schedule types: Lab, Lecture, Combined lecture and lab Description: This class will provide an in-depth introduction into Department/School: Microbiology & Mol Gen fundamental principles that apply to any microorganism and will provide MICR 5273 Advanced Principles of Microbial Pathogenesis an intellectual framework to understand all cells. The fundamentals Description: Advanced study of the pathogenic mechanisms used by discussed will be illustrated through a combination of classical and microbial pathogens to cause disease. Principles of and recent scientific breakthroughs. It will provide a solid, deep foundation pathogen-host interactions that lead to disease pathology. for a successful academic career in microbiology. Previously offered as Credit hours: 3 MICR 6163. May not be used for degree credit with MICR 4163. Contact hours: Lecture: 3 Contact: 3 Credit hours: 3 Levels: Graduate Contact hours: Lecture: 3 Contact: 3 Schedule types: Lecture Levels: Graduate Department/School: Microbiology & Mol Gen Schedule types: Lecture MICR 5323 Cellular Energy Metabolism Department/School: Microbiology & Mol Gen Prerequisites: MICR 3033 or BIOC 3653. MICR 5203 Bioinformatics Description: An exploration of the principals and mechanisms of energy Prerequisites: MICR 3033 or BIOC 3653 or equivalent. utilization and transformation in animals, plants, and microbial systems. Description: Fundamental concepts of biological sequence information The course covers a range of topics from basic molecular mechanisms and inferential techniques to assign structure, function, and evolutionary to recent advances in understanding energy flow in whole organisms. It relationship among genes and proteins. No prior programming necessary, includes new insights into the nanomachines involved in cell movement but familiarity with computer desktop assumed. No credit for students as well current genome-enabled approaches to understanding cellular with credit in MICR 4203. Course previously offered as CLML 5203. energy metabolism. May not be used for degree credit with MICR 4323. Credit hours: 3 Credit hours: 3 Contact hours: Lecture: 3 Contact: 3 Contact hours: Lecture: 3 Contact: 3 Levels: Graduate Levels: Graduate Schedule types: Lecture Schedule types: Lecture Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen MICR 5233 Advanced Cell and Molecular Biology MICR 5333 Controversies in Vaccinology Prerequisites: MICR 3033. Prerequisites: OSU graduate student status or permission of instructor. Description: Advanced topics in cell and molecular biology including Description: Public misconceptions about science abound, however, regulatory mechanisms of gene expression, protein function, cell these misconceptions have a major impact on perception of research structure and organization, cell division, and development. No credit for and public policy. Examples of themes in science as portrayed, for students with credit in MICR 4233. example, in film will be explored and critically discussed. Ways to improve Credit hours: 3 communication between the scientist and the general public will be Contact hours: Lecture: 3 Contact: 3 evaluated. Levels: Graduate Credit hours: 3 Schedule types: Lecture Contact hours: Lecture: 3 Contact: 3 Department/School: Microbiology & Mol Gen Levels: Graduate MICR 5253 Concepts in Medical Genetics Schedule types: Lecture Prerequisites: BIOL 3023. Department/School: Microbiology & Mol Gen Description: Application of genetic principles in the study of human diseases, including the inheritance, molecular mechanisms, detection, characterization, and discovery of human genes. No credit for students with credit in MICR 4253. Credit hours: 3 Contact hours: Lecture: 3 Contact: 3 Levels: Graduate Schedule types: Lecture Department/School: Microbiology & Mol Gen Microbiology and Molecular Genetics 9

MICR 5423 Antibiotics and Antibiotic Resistance MICR 5990 Special Problems Description: This course begins with a basic history of antibiotics, Prerequisites: Permission of instructor. including their discovery and industrial development. It covers the major Description: Investigations in the field of Microbiology. Offered for classes of antibiotics, their structures and mechanisms of action, and variable credit, 1-4 credit hours, maximum of 10 credit hours. the mechanisms by which bacteria become resistant to antibiotics. Credit hours: 1-4 Also covered are industrial and commercial considerations, antibiotic Contact hours: Contact: 1-4 Other: 1-4 stewardship, current challenges, and future prospects for antibiotic Levels: Graduate discovery and use. Same course as MICR 4423. Schedule types: Independent Study Credit hours: 3 Department/School: Microbiology & Mol Gen Contact hours: Lecture: 3 Contact: 3 MICR 6000 Dissertation Levels: Graduate Prerequisites: Consent of major adviser. Schedule types: Lecture Description: Research in microbiology for the PhD degree. Offered for Department/School: Microbiology & Mol Gen variable credit, 1-15 credit hours, maximum of 45 credit hours. MICR 5513 Grant Proposal Preparation Credit hours: 1-15 Prerequisites: Admission into Microbiology graduate program. Formats, Contact hours: Contact: 1-15 Other: 1-15 strategies, and styles of research grant proposal writing. Levels: Graduate Description: Activities include hypothesis development and critical Schedule types: Independent Study evaluation of research proposals. Department/School: Microbiology & Mol Gen Credit hours: 3 MICR 6112 Molecular Biology of Bacterial Viruses Contact hours: Lecture: 2 Contact: 3 Other: 1 Prerequisites: MICR 4123 and MICR 4133. Levels: Graduate Description: Advanced study of bacteriaphages. Course previously Schedule types: Discussion, Combined lecture & discussion, Lecture offered as MICR 6113. Department/School: Microbiology & Mol Gen Credit hours: 2 MICR 5524 Biological Laboratory Instrumentation Contact hours: Lecture: 3 Contact: 3 Prerequisites: CHEM 1515 or equivalent and PBIO 1404 or MICR 2123 or Levels: Graduate BIOL 1604 or equivalents or consent of instructor. Schedule types: Lecture Description: Lecture and laboratory course in biological instrumentation Department/School: Microbiology & Mol Gen use, theory, experimental design, maintenance, and troubleshooting. MICR 6120 Recent Advances in Microbiology Topics include liquid handling systems, pH/ISE meters, electrophoresis, Prerequisites: One graduate course in biochemistry. spectrophotometers, centrifuges, chromatography, thermocyclers, and Description: Discussion and evaluation of recent scientific contributions DNA sequencers. May not be used for degree credit with BIOL 4524; in terms of the living organism. Offered for fixed credit, 1 credit hour, MICR 4524; PBIO 4524. Previously offered as BIOL 5524; PBIO 5524. maximum of 6 credit hours. Credit hours: 4 Credit hours: 1 Contact hours: Lecture: 2 Lab: 4 Contact: 6 Contact hours: Contact: 1 Other: 1 Levels: Graduate Levels: Graduate Schedule types: Lab, Lecture, Combined lecture and lab Schedule types: Independent Study Department/School: Microbiology & Mol Gen Department/School: Microbiology & Mol Gen MICR 5543 Microbial Genomics and Bioinformatics MICR 6133 Cellular Microbiology Prerequisites: MICR 2123; MICR 3033 or MICR 3223 or equivalents. Prerequisites: A strong undergraduate level background in microbiology, Description: Basic approaches and strategies for microbial genome biochemistry or cell biology is expected. analysis, and hands-on training on the subject. Graduate students Description: The molecular interactions between intracellular parasites enrolled in the class are expected to give a comprehensive presentation and their host cells will be explored, emphasizing the manipulation of on the genomic analysis done throughout the semester. The presentation normal cellular processes to the benefit of the parasite. The course should be a manuscript format with a brief Introduction, Materials and will involve critical reading of the current literature and development Methods, Results, and Discussion. A comprehensive use of all principals of an understanding of molecular microbe and cell biology research covered in class is expected and will be used for evaluation. Credit will techniques. also be given to handling questions and presentation skills. May not be Credit hours: 3 used for degree credit with MICR 4543. Contact hours: Lecture: 3 Contact: 3 Credit hours: 3 Levels: Graduate Contact hours: Lecture: 3 Contact: 3 Schedule types: Lecture Levels: Graduate Department/School: Microbiology & Mol Gen Schedule types: Lecture Department/School: Microbiology & Mol Gen MICR 6143 Advanced Microbial Physiology Prerequisites: MICR 3223 or consent of instructor. Description: Discussion of selected topics in microbial physiology. Critical analysis of research papers. Credit hours: 3 Contact hours: Lecture: 3 Contact: 3 Levels: Graduate Schedule types: Lecture Department/School: Microbiology & Mol Gen 10 Microbiology and Molecular Genetics

MICR 6153 Molecular Microbial Genetics Description: Examine modern and classical genetic techniques to Graduate Programs understand the underlying principles of molecular genetics using original The department offers graduate studies leading to the MS and literature. PhD degrees in various areas of concentration, including microbial Credit hours: 3 physiology, microbial genetics, , microbial pathogenesis, Contact hours: Lecture: 3 Contact: 3 immunology, cell biology and the human microbiome. Levels: Graduate Schedule types: Lecture Prerequisites Department/School: Microbiology & Mol Gen Applicants for admission must have received the baccalaureate degree MICR 6223 Molecular Environmental Microbiology and Ecology from an accredited university or college and must have completed a Prerequisites: MICR 3223 or consent of instructor. minimum of 30 semester credit hours in the biological and physical Description: This course focuses on fundamental and applied aspects sciences. The Aptitude Test portion of the Graduate Record Examination of microbial ecology, physiology and genomics. The course aims to is required of all applicants. A majority of the departmental graduate highlight the value of microbes in applied disciplines such as medicine, faculty must approve applicants. agriculture, and biotechnology. Recent advances in methodologies and approaches for examining the phylogenetic and metabolic The Master of Science Degree diversity of microorganisms in various ecosystems, as well as tools for In addition to the general requirements for the degree, the following understanding microbial composition and identification of departmental requirements must be met in attaining 30 credit hours with rare members of microbial community will be highlighted. thesis. The plan of study must include six thesis hours and one credit Credit hours: 3 hour microbiology seminar for the traditional degree. An accelerated MS Contact hours: Lecture: 3 Contact: 3 degree is available that is largely coursework and literature based, which Levels: Graduate allows completion of the degree in as little as 12 months. Literature Schedule types: Lecture research includes at least six credit hours in independent study. Department/School: Microbiology & Mol Gen MICR 6253 Microbial Evolution Candidates for the MS degree are expected to attend and participate in Prerequisites: MICR 2123, MICR 2132, BIOC 3653, BIOL 3023. all departmental seminars. A final oral examination covering the thesis Description: The mechanisms and results of microbial evolution in (or literature research for the accelerated program) is administered by the nature and in the laboratory, with emphasis on microbes as model advisory committee following a public presentation of the candidate’s evolutionary systems, , classification and phylogeny, research. and discussion of protobiology and the probable fate of engineered microbes. The Doctor of Philosophy Degree Credit hours: 3 The study plan of a student entering the program with a bachelor's degree Contact hours: Lecture: 3 Contact: 3 must include 30 credit hours in the biological and physical sciences. Levels: Graduate Those entering with a master's degree must include 15 hours in courses Schedule types: Lecture other than dissertation credits which were not included in the master's Department/School: Microbiology & Mol Gen study plan. Three hours of microbiology seminar must be included. MICR 6323 Candidates for the PhD are expected to attend and participate in all Prerequisites: A strong undergraduate level background in microbiology, departmental seminars. Candidates for the PhD degree must pass both biochemistry, or cell biology is expected. a written and an oral qualifying examination. The final examination Description: Discussion of current literature on the mechanisms of covering the dissertation research is given promptly after the candidate prokaryotic and eukaryotic signal and gene regulation. has given a public seminar on his/her research work. Credit hours: 3 Contact hours: Lecture: 3 Contact: 3 Levels: Graduate Minors Schedule types: Lecture • Microbiology (MICR), Minor (http://catalog.okstate.edu/arts- Department/School: Microbiology & Mol Gen sciences/microbiology-molecular-genetics/microbiology-minor/) Undergraduate Programs Faculty • Microbiology/Cell & Molecular Biology, BS (http:// Tyrrell Conway, PhD—Regents Professor and Department Head catalog.okstate.edu/arts-sciences/microbiology-molecular-genetics/ Professors: Robert L. Burnap, PhD (Regents Professor and Vennerberg microbiology-cell-molecular-biology-bs/) Chair in Bioinformatics); Mostafa S. Elshahed, PhD; Babu Z. Fathepure, • Microbiology/Cell & Molecular Biology: Medical Laboratory Science, PhD; Jeffrey A. Hadwiger, PhD; Wouter D. Hoff, PhD; Rolf A. Prade, BS (http://catalog.okstate.edu/arts-sciences/microbiology- PhD; Marianna A. Patrauchan, PhD molecular-genetics/microbiology-cell-molecular-biology-medical- Associate Professors: Erika Lutter, PhD; Noha Youssef, PhD laboratory-science-bs/) Assistant Professors: Matt Cabeen, PhD; Randy Morgenstein, PhD; Karen • Microbiology/Cell & Molecular Biology: Pre-Medical Professional, Wozniak, PhD; Avi Mitra, PhD; Sabrina Beckmann, PhD BS (http://catalog.okstate.edu/arts-sciences/microbiology- molecular-genetics/microbiology-cell-molecular-biology-pre-medical- professional-bs/)