Selected Papers of William L. White
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Palliative Care Case of the Month
PALLIATIVE CARE CASE OF THE MONTH “Treating Non-Infectious Diarrhea” by Robert Arnold, MD Volume 19, No. 98 August, 2019 Case 1: Mr. Jones is a 58-year-old man with short gut Three drugs are used because of their ability to slow down the syndrome. Palliative Care was consulted for goals of care, gut, allowing for more time for absorption of intestinal fluids a however quickly it became clear uncontrolled diarrhea was a decrease of diarrhea. The most well-know is loperamide, a larger priority. He said having to change the bag every few hours synthetic opiate which has minimal absorption. The dosing is 4 completely interfered with his living a normal life. He said, “I’d mg after one’s first bowel movement and then 2 mg after every rather die than have all of this diarrhea.” unformed stool, up to 16 mg (in palliative care patients there is some data for use up to 54 mg).9, 10 Loperamide should be Case 2: A 62-year-old woman with non-small cell lung cancer continued for 12 hours after diarrhea is stopped. Adverse effects is receiving immunotherapy. She has done quite well but is include mostly constipation, abdominal cramps, nausea and distressed by her diarrhea. She tried Lomotil and Imodium but rarely CNS effects like fatigue or dizziness. Cases of torsades de neither worked. When seeing her palliative care doctor, she said, pointes and death have been reported with higher than “It isn’t worth treating my cancer if I can’t live a normal life.” 9 recommended doses. -
Anti-Diarrheal Activity and Brine Shrimp Lethality Bioassay of Methanolic Extract of Cordyline Fruticosa (L.) A
Naher et al. Clinical Phytoscience (2019) 5:15 https://doi.org/10.1186/s40816-019-0109-z ORIGINAL CONTRIBUTION Open Access Anti-diarrheal activity and brine shrimp lethality bioassay of methanolic extract of Cordyline fruticosa (L.) A. Chev. leaves Sharmin Naher1*, Md. Abdullah Aziz1, Mst. Irin Akter2, S. M. Mushiur Rahman1, Sadiur Rahman Sajon1 and Kishor Mazumder1,3 Abstract Background: Cordyline fruticosa (L.) A. Chev. (Asparagaceae) is a plant which is traditionally used for the treatment of cough, bloody cough, diarrhea, dysentery, high fever, difficulties in urine, bloody urine, small pox, madness, skin eruptions, joint pains, rheumatic bone pains, sore throat, neck pain, bleeding hemorrhoids and inflammation in the digestive tract. Therefore, the present work aims to investigate the antidiarrheal and cytotoxic activities of methanolic extract of Cordyline fruticosa leaves in mice and brine shrimp, respectively. Methods: The effects of the methanol extract of Cordyline fruticosa leaves (MCFL) on castor oil-induced diarrhea, magnesium sulphate induced diarrhea and charcoal meal test in mice were investigated. In addition, brine shrimp lethality bioassay method was used to evaluate cytotoxic activity of MCFL. Results: In castor oil induced diarrheal test, MCFL at the dose of 200, 400 and 800 mg/kg body weight significantly (∗P< 0.05, versus control) and dose-dependently reduced the frequency of diarrhea. The frequency of magnesium sulphate-induced diarrhea was significantly reduced by MCFL at the dose of with 800 mg/kg. In the charcoal meal test, the extract at the dose of 400 and 800 mg/kg body weight significantly (∗P< 0.05) reduced the distance travelled by charcoal along the intestinal tract when compare with control. -
Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017
Q UO N T FA R U T A F E BERMUDA PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 BR 111 / 2017 The Minister responsible for health, in exercise of the power conferred by section 48A(1) of the Pharmacy and Poisons Act 1979, makes the following Order: Citation 1 This Order may be cited as the Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017. Repeals and replaces the Third and Fourth Schedule of the Pharmacy and Poisons Act 1979 2 The Third and Fourth Schedules to the Pharmacy and Poisons Act 1979 are repealed and replaced with— “THIRD SCHEDULE (Sections 25(6); 27(1))) DRUGS OBTAINABLE ONLY ON PRESCRIPTION EXCEPT WHERE SPECIFIED IN THE FOURTH SCHEDULE (PART I AND PART II) Note: The following annotations used in this Schedule have the following meanings: md (maximum dose) i.e. the maximum quantity of the substance contained in the amount of a medicinal product which is recommended to be taken or administered at any one time. 1 PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 mdd (maximum daily dose) i.e. the maximum quantity of the substance that is contained in the amount of a medicinal product which is recommended to be taken or administered in any period of 24 hours. mg milligram ms (maximum strength) i.e. either or, if so specified, both of the following: (a) the maximum quantity of the substance by weight or volume that is contained in the dosage unit of a medicinal product; or (b) the maximum percentage of the substance contained in a medicinal product calculated in terms of w/w, w/v, v/w, or v/v, as appropriate. -
Western Judicial Circuit Felony Drug Court
Western Judicial Circuit Felony Drug Court (Athens-Clarke and Oconee Counties) PARTICIPANT HANDBOOK This handbook belongs to: 325 E. Washington Street, Suite 210 Athens, Georgia 30601 (706) 208-7078 (706) 613-3179 (fax) Table of Contents Welcome 3 Overview 4-5 Confidentiality 5 Treatment 5 Program Phases 6-10 Commencement 11 Program Rules 12-14 Program Fees 15 The Drug Court Team 15 Staffings 15 Court Appearances 16 Incentives 17 Sanctions and Treatment Responses 17 Termination 18 Drug/Chemical Testing 19 Prohibited Drugs/Permitted Medications 20-27 Travel/Leave Requests 27 Compliance & Home Visits/Job Checks, Searches 28 Search Requirements 28 Commencement Ceremony 29 Conclusion 29 Important Phone Numbers 30 Community Resources 31 Attachment I: Random Drug Screen Policy Attachment II: Urine Abstinence Testing/Incidental Alcohol Exposure Contract (original signed copy on file with Felony Drug Court) Attachment III: Emergency On-call Telephone Policy Attachment IV: Felony Drug Court Contract 2 Welcome to the Western Judicial Circuit Felony Drug Court! This Handbook was designed to answer your questions and provide specific information about what you must do in order to successfully complete the requirements of the Western Judicial Circuit Felony Drug Court Program. As a participant, you are expected to follow the instructions found in this Handbook, as well as the instructions of the Felony Drug Court Judge, Staff, and Treatment Provider. You will also be expected to comply with the treatment plan developed for you by your Treatment Provider. This handbook is not exhaustive and there is no possible way to make it complete and detailed to answer every question or situation that arises. -
Drugs of Abuseon September Archived 13-10048 No
U.S. DEPARTMENT OF JUSTICE DRUG ENFORCEMENT ADMINISTRATION WWW.DEA.GOV 9, 2014 on September archived 13-10048 No. v. Stewart, in U.S. cited Drugs of2011 Abuse EDITION A DEA RESOURCE GUIDE V. Narcotics WHAT ARE NARCOTICS? Also known as “opioids,” the term "narcotic" comes from the Greek word for “stupor” and originally referred to a variety of substances that dulled the senses and relieved pain. Though some people still refer to all drugs as “narcot- ics,” today “narcotic” refers to opium, opium derivatives, and their semi-synthetic substitutes. A more current term for these drugs, with less uncertainty regarding its meaning, is “opioid.” Examples include the illicit drug heroin and pharmaceutical drugs like OxyContin®, Vicodin®, codeine, morphine, methadone and fentanyl. WHAT IS THEIR ORIGIN? The poppy papaver somniferum is the source for all natural opioids, whereas synthetic opioids are made entirely in a lab and include meperidine, fentanyl, and methadone. Semi-synthetic opioids are synthesized from naturally occurring opium products, such as morphine and codeine, and include heroin, oxycodone, hydrocodone, and hydromorphone. Teens can obtain narcotics from friends, family members, medicine cabinets, pharmacies, nursing 2014 homes, hospitals, hospices, doctors, and the Internet. 9, on September archived 13-10048 No. v. Stewart, in U.S. cited What are common street names? Street names for various narcotics/opioids include: ➔ Hillbilly Heroin, Lean or Purple Drank, OC, Ox, Oxy, Oxycotton, Sippin Syrup What are their forms? Narcotics/opioids come in various forms including: ➔ T ablets, capsules, skin patches, powder, chunks in varying colors (from white to shades of brown and black), liquid form for oral use and injection, syrups, suppositories, lollipops How are they abused? ➔ Narcotics/opioids can be swallowed, smoked, sniffed, or injected. -
Opioid Epidemic in the US
When the CDC published opioid-prescribing guidelines Opium has been around since at least 3400 BC. Opioid Epidemic in the U.S.: in 2016, it brought national attention to a problem Known as the "joy plant," it was cultivated by plaguing Americans across the country. Overdose Sumerians in lower Mesopotamia, now current-day deaths related to prescription opioids and heroin Iraq. Its use, both as a pain reliever and soporific, addiction have reached epidemic proportions. In fact, spread through the Middle East, India, Greece, How Did We Get Here? they have quadrupled since 1999, according to the CDC.1 China and Europe. [PBS] 1 CDC 1700s Colonial America 1800s-30s 1850s-60s 1870s-90s 1900s-10s 1920s MORPHINE 1920: HYDROCODONE NARCOMANIA FREE HEROIN Friedrich Wilhelm A German pharmaceutical Physicians raise concerns with morphine addiction, A philanthropic Sertürner of Germany company develops also known as “narcomania.”1 vorganization isolates morphine from hydrocodone, another provides free heroin to morphine addicts to help opium.1 He calls it opiate painkiller.1 OPIUM AND LAUDANUM Americans are now buying over-the-counter pills and 1 morphine, after them quit. Americans crush the pills and inhale Doctors prescribe opium to their patients to manage 1855: HYPODERMIC NEEDLE elixirs that contain opiates to treat menstrual cramps, 2 Morpheus, the Greek the powder for a more intense high. pain as well as help with dysentery, coughs, and other Alexander Wood of Scotland devises the teething and other aches and pains. 1923: LEGAL NARCOTICS BANNED god of dreams.2 maladies. Also popular are laudanum, an opium first hypodermic needle to administer morphine 1906: FOOD AND DRUGS ACT All legal narcotics are banned under the U.S. -
Nutrition Education Intervention and Substance Abuse Treatment Outcomes
University of Tennessee, Knoxville TRACE: Tennessee Research and Creative Exchange Doctoral Dissertations Graduate School 12-2004 Nutrition Education Intervention and Substance Abuse Treatment Outcomes Louise Patricia Grant University of Tennessee - Knoxville Follow this and additional works at: https://trace.tennessee.edu/utk_graddiss Part of the Home Economics Commons Recommended Citation Grant, Louise Patricia, "Nutrition Education Intervention and Substance Abuse Treatment Outcomes. " PhD diss., University of Tennessee, 2004. https://trace.tennessee.edu/utk_graddiss/1675 This Dissertation is brought to you for free and open access by the Graduate School at TRACE: Tennessee Research and Creative Exchange. It has been accepted for inclusion in Doctoral Dissertations by an authorized administrator of TRACE: Tennessee Research and Creative Exchange. For more information, please contact [email protected]. To the Graduate Council: I am submitting herewith a dissertation written by Louise Patricia Grant entitled "Nutrition Education Intervention and Substance Abuse Treatment Outcomes." I have examined the final electronic copy of this dissertation for form and content and recommend that it be accepted in partial fulfillment of the equirr ements for the degree of Doctor of Philosophy, with a major in Human Ecology. Dileep S. Sachan, Major Professor We have read this dissertation and recommend its acceptance: Betsy Haughton, Bill Wallace, James Bailey Accepted for the Council: Carolyn R. Hodges Vice Provost and Dean of the Graduate School (Original signatures are on file with official studentecor r ds.) To the Graduate Council: I am submitting herewith a dissertation written by Louise Patricia Grant entitled "Nutrition Education Intervention and Substance Abuse Treatment Outcomes". I have examined the final paper copy of this dissertation for form and content and recommend that it be accepted in partial fulfillment of the requirements for the degree of Doctor of Philosophy, with a major in Human Ecology. -
Narcotic Analgesics I Blanton SLIDE 1: We Will Be Spending the Next 90 Minutes Discussing Narcotic Analgesics- That Is Morphine, Oxycodone, Heroin, Etc
Narcotic Analgesics I Blanton SLIDE 1: We will be spending the next 90 minutes discussing narcotic analgesics- that is morphine, oxycodone, heroin, etc. These drugs act primarily thru the opiate receptor system. I always like to begin by presenting two factoids that I believe illustrate the power of this system: (1) Ok imagine you are in pain! Now I tell you that I am going to give you an injection of morphine or heroin. Even if I instead give you an injection of just saline- 50% of you will report that your pain is significantly reduced- that is quite a placebo effect. However, if instead of saline I give you an injection of Naloxone, an opiate receptor antagonist- the placebo effect is eliminated. In other words you are activating your opiate receptor system to induce analgesia. (2) acupuncture can be used to reduce pain. However, Naloxone will block this effect- in otherwords the acupuncture is activating your opiate receptor system. SLIDE 1A: The use of narcotic analgesics for effective pain management has certainly had its flip side……. With prescription narcotic analgesics helping to fuel the current heroin epidemic…. Back to SLIDE 1: So narcotic analgesics. The name narcotic is somewhat misleading, because it implies narcosis or somnolence. The name opiate or opioid is more precise because it connotes analgesia, without causing sleep or loss of consciousness. SLIDE 2: The terms opiate or opioid, as you are probably aware, refers to opium, the crude extract of the Poppy plant, Papaver somniferum. Opium comes from the seed pod of the plant after the petals have dropped. -
The Prevention and Treatment of Drug Misuse in Britain
If you have issues viewing or accessing this file contact us at NCJRS.gov. .. " FW The prevention and treatment of drug misuse in Britain "I Issued by Rererence Division BRITISH INFORMATION SERVICES All Agency of the British Government 845 THIRD AVENUE, NEW YORK, N.Y. ]0022 This material is prepared, edited, issued or circulated by British Information Servic(!s, 845 Third Avenue, New York, N. Y.l0022, which is registered under the Foreign Agents Registration Act as an agent of the Brilish Government. This material is filed with the Department of Justice where the required registration statement is available for public inspection. Registration does not indicate approval 0/ the contents of this material by the United States Government. PRINTED IN ENGLAND BY TRADE UNION LABOR BY COLUNS AND WILSON LTD., ANDOVER The prevention and treatment of drug misuse in Britain Prepared by REFERENCE DIVISION CENTRhL OFFICE OF INFORMATION, LONDON Oclo~'er 1978 Quote No RS94S/78 CLASSIFICATION 4(c) N.B.-This pamphlet is i//tellded to be used for referellce purposes alld may be freely used ill preparing articles, speeches, broadcasts, elc. No acknowledgment is necessary. Please Ilote the date ofpreparation. Tire text gives general gUidance only, and should 1I0t be treated as an authoritative statement of the law. Pamphlets ill this series may be obtained from the Tllformation Office at tlte British Embassy, Consulate or High Commission in tile inquirer's Co/lIltl'Y of residellce. CONTENTS Page INTRODUCTION 1 BACKGROUND .. 3 PREVENTING DRUG MISUSE 8 The Law 8 Health Education 17 TREATMENT AND REHABILITATION .. 20 Narcotic Drug Misuse and the Role of the Clinics 20 Treating Other Forms of Drug Misuse 26 Rehabilitation 26 INFORMATION AND RESEARCH ., 29 APPENDICES 1. -
Kratom in Tennessee
Kratom in Tennessee Story by Jeff Hargis PhD TMC What is it, What does it do, Where is it from, What are the possible risks or benefits and what you should know before buying it? East West Herbal is located at 3028 Gallatin Pike in East Nashville. We carry over 300 medicinal herbs, spices, coffees and teas. We pride ourselves in helping people to understand more about herbs and how they work along with their possible risks and benefits. We hope this article will act as a guide to consumers who are on a quest to explore Kratom; and who are not fully aware of the benefits or risks involved when buying an herbal supplement such as kratom. Things you should know when it comes to Possible Uses, Risks, Pricing, Availability, Quality Sourcing, Purity and Freshness are all important factors. This article is to give you an basic guide about what you may be buying, how much it should cost and what you should look for in a vendor, so you may evaluate with a better understanding as to whether the product is right for you and where you want to purchase Kratom from. All information contained in this article is provided for general information purposes only and is not intended as medical advice for the reader. Do not use this information to diagnose a health problem without first consulting a qualified health care provider. No physician- patient relationship is created by reading this article. What is Kratom? Mitragyna Speciosa AKA Kratom Leaf is a member of the coffee family. -
Section B Changed Classes/Guidelines Final
EPHMRA ANATOMICAL CLASSIFICATION GUIDELINES 2019 Section B Changed Classes/Guidelines Final Version Date of issue: 24th December 2018 1 A3 FUNCTIONAL GASTRO-INTESTINAL DISORDER DRUGS R2003 A3A PLAIN ANTISPASMODICS AND ANTICHOLINERGICS R1993 Includes all plain synthetic and natural antispasmodics and anticholinergics. A3B Out of use; can be reused. A3C ANTISPASMODIC/ATARACTIC COMBINATIONS This group includes combinations with tranquillisers, meprobamate and/or barbiturates except when they are indicated for disorders of the autonomic nervous system and neurasthenia, in which case they are classified in N5B4. A3D ANTISPASMODIC/ANALGESIC COMBINATIONS R1997 This group includes combinations with analgesics. Products also containing either tranquillisers or barbiturates and analgesics to be also classified in this group. Antispasmodics indicated exclusively for dysmenorrhoea are classified in G2X1. A3E ANTISPASMODICS COMBINED WITH OTHER PRODUCTS r2011 Includes all other combinations not specified in A3C, A3D and A3F. Combinations of antispasmodics and antacids are classified in A2A3; antispasmodics with antiulcerants are classified in A2B9. Combinations of antispasmodics with antiflatulents are classified here. A3F GASTROPROKINETICS r2013 This group includes products used for dyspepsia and gastro-oesophageal reflux. Compounds included are: alizapride, bromopride, cisapride, clebopride, cinitapride, domperidone, levosulpiride, metoclopramide, trimebutine. Prucalopride is classified in A6A9. Combinations of gastroprokinetics with other substances -
MSIR (Morphine) Medical Facts from Drugs.Com 04/07/2015
MSIR (morphine) medical facts from Drugs.com 04/07/2015 Browse all medications A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Advanced Search Phonetic Search Drugs A-Z Pill Identifier Interactions Checker News Health Professionals Q & A Mednotes Apps Home → Conditions → Pain → MSIR Print Share Sign In or Register MSIR Related Information Availability Pregnancy Category Generic Name: morphine (MOR feen) Prescription only Risk cannot be ruled out Brand Name: AVINza, Kadian, MS Contin CSA Schedule WADA Class High potential for abuse Anti-Doping Classification Overview Side Effects Dosage Interactions More Reviews Average User Rating Reduce Nerve Pain Now Don't Let Neuropathy Symptoms Slow You Down. Get A Free Trial 1 User Review 9.0 Rate it! Now! Manufacturer What is MSIR (morphine)? Purdue Pharma LP Morphine is an opioid pain medication. An opioid is sometimes called a narcotic. Drug Class Morphine is used to treat moderate to severe Narcotic analgesics pain. Short-acting morphine is taken as needed for pain. Related Drugs The extended-release form of this medicine is Chronic Pain for around-the-clock treatment of pain. This tramadol form of morphine is not for use on an as- oxycodone needed basis for pain. Cymbalta Percocet Morphine is not for treating short-term pain just fentanyl after surgery unless you were already taking morphine morphine before the surgery. duloxetine methadone Morphine may also be used for purposes not Dilaudid listed in this medication guide. OxyContin Ultram More... Pain What is the most important information I should know about tramadol MSIR (morphine)? oxycodone naproxen You should not take this medicine if you have severe asthma or breathing problems, a blockage in acetaminophen your stomach or intestines, or a bowel obstruction called paralytic ileus.