CORE Metadata, citation and similar papers at core.ac.uk Provided by Nature Precedings The History, Development and Impact of Computed Imaging in Neurological Diagnosis and Neurosurgery: CT, MRI, and DTI by Aaron G. Filler, MD, PhD, FRCS Department of Neurosurgery Institute for Nerve Medicine Santa Monica, California Corresponding author: Aaron Filler, MD, PhD, FRCS 2716 Ocean Park Blvd., #3082 Santa Monica, CA 90405 Ph: 310 621-1983 Fx: 310 664-1916
[email protected] Key words: CT Scanning, History, Magnetic Resonance Imaging, Diffusion Tensor Imaging, Tractography, Neurography, fMRI Running Head: History of CT, MRI, and DTI No funding sources ‐ 1 ‐ The history, development and impact of computed imaging in neurological diagnosis and neurosurgery: CT, MRI, and DTI by Aaron Filler, MD, PHD, FRCS Abstract - A steady series of advances in physics, mathematics, computers and clinical imaging science have progressively transformed diagnosis and treatment of neurological and neurosurgical disorders in the 115 years between the discovery of the X-ray and the advent of high resolution diffusion based functional MRI. The story of the progress in human terms, with its battles for priorities, forgotten advances, competing claims, public battles for Nobel Prizes, and patent priority litigations bring alive the human drama of this remarkable collective achievement in computed medical imaging. ‐ 2 ‐ Aaron Filler, MD, PhD, FRCS The history, development and impact of computed imaging in neurological diagnosis and neurosurgery: CT, MRI, and DTI Introduction Atkinson Morley's Hospital is a small Victorian era hospital building standing high on a hill top in Wimbledon, about 15 miles southwest of the original St.