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Book of Abstracts 2021 BOOK OF ABSTRACTS Preface Organisation Research in Groningen Congress Abstracts Plenary Abstracts Oral Abstracts Poster Postscript 2 Table of Contents Preface � � � � � � � � � � � � � � � � � � � � � � � � � � � 5 Cell Biology � � � � � � � � � � � � � � � � � � � � � � � 99 Tessa de Bruin � � � � � � � � � � � � � � � � � � � � � � 6 Endocrinology & Diabetes � � � � � � � � � � � � � �106 Prof� Marian Joëls MD PhD � � � � � � � � � � � � � � � 7 Pediatrics, Obstetrics & Reproductive health � �110 Organisation � � � � � � � � � � � � � � � � � � � � � � � 8 Neurology & Neurosurgery � � � � � � � � � � � � �115 Executive Board � � � � � � � � � � � � � � � � � � � � � 9 Cardiology & Vascular medicine � � � � � � � � � �122 Advisory Board � � � � � � � � � � � � � � � � � � � � � 10 Oncology I � � � � � � � � � � � � � � � � � � � � � � � �128 President, Secretary, Treasurer � � � � � � � � � � � 11 Pulmonology � � � � � � � � � � � � � � � � � � � � � �134 Scientific Programme � � � � � � � � � � � � � � � � � 12 Oral Sessions II � � � � � � � � � � � � � � � � � � � � 139 Sponsors & Fundraising � � � � � � � � � � � � � � � 13 Public health II � � � � � � � � � � � � � � � � � � � � �140 International Contacts � � � � � � � � � � � � � � � � 14 Oncology II � � � � � � � � � � � � � � � � � � � � � � �146 Hosting & Logistics � � � � � � � � � � � � � � � � � � 15 Epidemiology � � � � � � � � � � � � � � � � � � � � � �153 Public Relations � � � � � � � � � � � � � � � � � � � � 16 Pharmacology � � � � � � � � � � � � � � � � � � � � �160 Research & Development � � � � � � � � � � � � � � 17 Biomaterials and Technical Medicine � � � � � � �167 First Year Crew � � � � � � � � � � � � � � � � � � � � � 18 Anaesthesiology & Surgery � � � � � � � � � � � � �174 Ambassadors � � � � � � � � � � � � � � � � � � � � � � 19 Nutrition � � � � � � � � � � � � � � � � � � � � � � � � �180 Dutch ambassadors � � � � � � � � � � � � � � � � � � 23 Infectious Disease � � � � � � � � � � � � � � � � � � �187 Partners � � � � � � � � � � � � � � � � � � � � � � � � � 24 Poster Sessions � � � � � � � � � � � � � � � � � � � � 193 Research in Groningen � � � � � � � � � � � � � � � �34 Biomaterials � � � � � � � � � � � � � � � � � � � � � � �194 The UMCG � � � � � � � � � � � � � � � � � � � � � � � � 35 Endocrinology � � � � � � � � � � � � � � � � � � � � �197 Junior Scientific Masterclass � � � � � � � � � � � � 36 General Surgery � � � � � � � � � � � � � � � � � � � �200 Graduate School of Medical Sciences � � � � � � � 37 Medical Physiology � � � � � � � � � � � � � � � � � �204 Research Master’s programmes � � � � � � � � � � 38 Pharmacology � � � � � � � � � � � � � � � � � � � � �208 Research Institutes � � � � � � � � � � � � � � � � � � 40 Rheumatology � � � � � � � � � � � � � � � � � � � � �214 ISCOMS Research Fellowships � � � � � � � � � � � 43 Cardiology � � � � � � � � � � � � � � � � � � � � � � � �218 IRF projects � � � � � � � � � � � � � � � � � � � � � � � 44 Nutrition � � � � � � � � � � � � � � � � � � � � � � � � �226 Summer schools � � � � � � � � � � � � � � � � � � � � 47 Dermatology � � � � � � � � � � � � � � � � � � � � � �228 Congress � � � � � � � � � � � � � � � � � � � � � � � � �48 Cell Biology � � � � � � � � � � � � � � � � � � � � � � �230 Programme ISCOMS 2021 � � � � � � � � � � � � � � 49 Opthalmology � � � � � � � � � � � � � � � � � � � � �235 Day chairs � � � � � � � � � � � � � � � � � � � � � � � � 51 Genetics � � � � � � � � � � � � � � � � � � � � � � � � �238 Jury members � � � � � � � � � � � � � � � � � � � � � 55 Paediatrics � � � � � � � � � � � � � � � � � � � � � � � �242 Awards � � � � � � � � � � � � � � � � � � � � � � � � � � 61 Pre-Course � � � � � � � � � � � � � � � � � � � � � � � � 62 Psychiatry � � � � � � � � � � � � � � � � � � � � � � � �248 Keynotes � � � � � � � � � � � � � � � � � � � � � � � � � 63 Geriatrics � � � � � � � � � � � � � � � � � � � � � � � � �254 Operation � � � � � � � � � � � � � � � � � � � � � � � � 67 ORL & Dental Surgery � � � � � � � � � � � � � � � � �259 Patient lecture � � � � � � � � � � � � � � � � � � � � � 68 Imaging � � � � � � � � � � � � � � � � � � � � � � � � �262 Workshops � � � � � � � � � � � � � � � � � � � � � � � 69 Obstetrics � � � � � � � � � � � � � � � � � � � � � � � �265 Social Programme � � � � � � � � � � � � � � � � � � � 76 Pulmonary Medicine � � � � � � � � � � � � � � � � �269 Nephrology � � � � � � � � � � � � � � � � � � � � � � �273 Plenary Session � � � � � � � � � � � � � � � � � � � � �77 Immunology � � � � � � � � � � � � � � � � � � � � � �276 Neurology � � � � � � � � � � � � � � � � � � � � � � � �280 Oral Sessions I � � � � � � � � � � � � � � � � � � � � � �92 Orthopaedics � � � � � � � � � � � � � � � � � � � � � �287 Public health & Infection � � � � � � � � � � � � � � � 93 Oncology � � � � � � � � � � � � � � � � � � � � � � � �291 3 Pathology � � � � � � � � � � � � � � � � � � � � � � � �300 Infectious Diseases � � � � � � � � � � � � � � � � � �305 Epidemiology � � � � � � � � � � � � � � � � � � � � � �313 Public Health � � � � � � � � � � � � � � � � � � � � � �321 Medical Microbiology � � � � � � � � � � � � � � � �335 Clinical Biochemistry � � � � � � � � � � � � � � � � �344 Reproductive Health � � � � � � � � � � � � � � � � �349 Postscripts � � � � � � � � � � � � � � � � � � � � � � � 354 Funds � � � � � � � � � � � � � � � � � � � � � � � � � � �355 Sponsors � � � � � � � � � � � � � � � � � � � � � � � � �356 Special Thanks � � � � � � � � � � � � � � � � � � � � �358 Committee of Recommendation � � � � � � � � � �360 Previous Keynotes � � � � � � � � � � � � � � � � � � �361 4 Preface Tessa de Bruin Prof� Marian Joëls MD PhD 5 Tessa de Bruin President ISCOMS 2021 Dear participants, It is with great pleasure that I welcome you to the digital version of the 28th edition of the International Student Congress of (bio)Medical Sciences� Over the past 28 years, ISCOMS has grown to become one of the world’s leading (bio)medical student congresses� However, this year, our congress cannot take place as planned due to the global outbreak of the COVID-19 pandemic� After a year of hard work of the Organising Committee, and, most importantly, after all the enthusiasm and support you as participants have always shown us, we organised a digital congress� Over the past year our Organising Committee has been working very hard to put together, a programme that all participants are able to follow from home� By doing so, we hope that ISCOMS can continue to provide students the opportunity to present their research on an international platform, to acquire knowledge by attending the programme, and to expand their network by interacting with other participants� Our online programme exists of a digital platform on which participants are able to attend three full days of inspiring lectures and student presentations� This year, for the first time ever, we chose a day theme namely ‘Nutrition’� On Wednesday the 9th of June, both keynote speakers, a couple of workshops and oral presentations will pay attention to this theme� On Monday we will start with the pre-course, a day in which enthusiastic students can improve their research skills by attending informative masterclasses� During the following three congress days, we will welcome Nobel Laureate prof� Sir Peter J� Ratcliffe MD, prof� Jaap Seidell PhD, prof� Marion Koopmans DVM PhD and last but not least prof� Ellen Roche PhD� On Tuesday we will kick-off with a keynote lecture by prof� Sir Peter J� Ratcliffe, who won the Nobel Prize in Physiology or Medicine in 2019� Prof� Sir Peter J� Ratcliffe is best known for his discovery on how cells sense and adapt to oxygen availability� In his lecture, Sir Peter J� Ratcliffe will talk about ‘Understanding cellular oxygen sensing mechanisms: implications for medicine’� After the congress, fourteen young and talented foreign (bio)medical students will start with the ISCOMS Research Fellowships where they will join the two-week online research internships at Research Institutes of the UMCG� Besides all the cons of the global outbreak of the COVID-19 pandemic, I also see the benefits� The people who did normally not have the ability to visit the physical ISCOMS versions, do now have the ability to visit ISCOMS in a digital way� On behalf of the entire Organising Committee, I wish you all a wonderful time and I hope you will enjoy ISCOMS as much as I did organising it! 6 Prof� Marian Joëls MD PhD Dean/Member of the Board of Directors University Medical Center Groningen Dear participants of ISCOMS 2021, It is my great pleasure to welcome all guests to the 28th edition of the International Student Congress Of (bio)Medical Sciences in Groningen, an annual event organized by students from Groningen for students from all over the world of which we are very proud� ISCOMS has become a tradition and is regarded by many as one of the highlights of the University Medical Center Groningen (UMCG) academic year� We would like to congratulate the Organising Committee for putting together such an exciting scientific programme� Again, this year’s ISCOMS edition hosts an impressive number of renowned speakers, among which are Jaap Seidell, Marion Koopmans, Ellen Roche and Nobelprize winner Sir Peter Ratcliffe� No doubt these and other speakers will be a source of inspiration to the participants� International contacts and collaborations are essential to push science forwards� The UMCG and the University of Groningen foster such international
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