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Udayathulla April-17 Modified.Pmd 97 98 Current Trends in Biotechnology and Pharmacy ISSN 0973-8916 (Print), 2230-7303 (Online) Editors Prof.K.R.S. Sambasiva Rao, India Prof. Karnam S. Murthy, USA [email protected] [email protected] Editorial Board Prof. Anil Kumar, India Dr.P. Ananda Kumar, India Prof. P.Appa Rao, India Prof. Aswani Kumar, India Prof. Bhaskara R.Jasti, USA Prof. Carola Severi, Italy Prof. Chellu S. Chetty, USA Prof. K.P.R. Chowdary, India Dr. S.J.S. Flora, India Dr. Govinder S. Flora, USA Prof. H.M. Heise, Germany Prof. Huangxian Ju, China Prof. Jian-Jiang Zhong, China Dr. K.S.Jagannatha Rao, Panama Prof. Kanyaratt Supaibulwatana, Thailand Prof.Juergen Backhaus, Germany Prof. Jamila K. Adam, South Africa Prof. P.B.Kavi Kishor, India Prof. P.Kondaiah, India Prof. M.Krishnan, India Prof. Madhavan P.N. Nair, USA Prof. M.Lakshmi Narasu, India Prof. Mohammed Alzoghaibi, Saudi Arabia Prof.Mahendra Rai, India Prof. Milan Franek, Czech Republic Prof.T.V.Narayana, India Prof. Nelson Duran, Brazil Dr. Prasada Rao S.Kodavanti, USA Prof. Mulchand S. Patel, USA Dr. C.N.Ramchand, India Dr. R.K. Patel, India Prof. P.Reddanna, India Prof. G.Raja Rami Reddy, India Dr. Samuel J.K. Abraham, Japan Dr. Ramanjulu Sunkar, USA Dr. Shaji T. George, USA Prof. B.J. Rao, India Prof. Sehamuddin Galadari, UAE Prof. Roman R. Ganta, USA Prof. B.Srinivasulu, India Prof. Sham S. Kakar, USA Prof. B. Suresh, India Dr. N.Sreenivasulu, Germany Prof. Swami Mruthinti, USA Prof.Sung Soo Kim, Korea Prof. Urmila Kodavanti, USA Prof. N. Udupa, India Assistant Editors Dr.Giridhar Mudduluru, Germany Dr. Sridhar Kilaru, UK Prof. Mohamed Ahmed El-Nabarawi, Egypt Prof. Chitta Suresh Kumar, India www.abap.co.in ISSN 0973-891699 Current Trends in Biotechnology and Pharmacy (An International Scientific Journal) Volume 11 Issue 2 April 2017 www.abap.co.in Indexed in Chemical Abstracts, EMBASE, ProQuest, Academic SearchTM, DOAJ, CAB Abstracts, Index Copernicus, Ulrich’s Periodicals Directory, Open J-Gate Pharmoinfonet.in Indianjournals.com and Indian Science Abstracts. Current Trends in Biotechnology and Pharmacy 100 Vol. 11 (2) April 2017, ISSN 0973-8916 (Print), 2230-7303 (Online) Association of Biotechnology and Pharmacy (Regn. No. 28 OF 2007) The Association of Biotechnology and Pharmacy (ABAP) was established for promoting the science of Biotechnology and Pharmacy. The objective of the Association is to advance and disseminate the knowledge and information in the areas of Biotechnology and Pharmacy by organising annual scientific meetings, seminars and symposia. Members The persons involved in research, teaching and work can become members of Association by paying membership fees to Association. The members of the Association are allowed to write the title MABAP (Member of the Association of Biotechnology and Pharmacy) with their names. Fellows Every year, the Association will award Fellowships to the limited number of members of the Association with a distinguished academic and scientific career to be as Fellows of the Association during annual convention. The fellows can write the title FABAP (Fellow of the Association of Biotechnology and Pharmacy) with their names. Membership details —————————————————————————————————————— — (Membership and Journal) India SAARC Others —————————————————————————————————————— — Individuals – 1 year Rs. 600 Rs. 1000 $100 LifeMember Rs. 4000 Rs. 6000 $500 Institutions – 1 year Rs. 1500 Rs. 2000 $200 (Journal only) Life member Rs.10000 Rs.12000 $1200 —————————————————————————————————————— — Individuals can pay in two instalments, however the membership certificate will be issued on payment of full amount. All the members and Fellows will receive a copy of the journal free Association of Biotechnology and Pharmacy (Regn. No. 28 OF 2007) #5-69-64; 6/19, Brodipet Current Trends in Biotechnology and Pharmacy 101 Vol. 11 (2) April 2017, ISSN 0973-8916 (Print), 2230-7303 (Online) Current Trends in Biotechnology and Pharmacy ISSN 0973-8916 Volume 11 (2) CONTENTS April 2017 Research Papers Multiple Parameter Optimization for Maximization of Exopolysaccharide Production from 103-112 Lactobacillus paraplantarum KM1 by Response Surface Methodology Kanika Sharma, Nivedita Sharma* and Ranjana Sharma Comparative Microbiological and Physico-Chemical Properties of Commercially available Baker’s Yeast and Fruit Juice Isolate (FJ1) 113-120 Hiranmay Malik, Priya Katyal and Param Pal Sahota Sonic Stimulation can affect Production of Quorum Sensing Regulated Pigment in Serratia 121-128 marcescens and Pseudomonas aeruginosa Vijay Kothari, Pooja Patel, Chinmayi Joshi, Brijesh Mishra, Shashikant Dubey and Milan Mehta Development of NEUROAchFET circuit for Patients Having Neurological Disorder 129-135 Rashmi Deka and Jiten Ch. Dutta β Screening, optimization and production of a novel - cyclodextrinase by Bacillus flexus 136-143 MSBC 2 Shwetha V, Sunil S More and Uday M Purification Strategies for Microbial Pectinases 144-159 E. Venkatanagaraju and G. Divakar Algorithm to Simulate a Chemically Induced DNA Logic Gate and Boolean Circuit 160-166 Kuntala Boruah, Rashmi Deka and Jiten Ch Dutta Statistical Optimization for Tannase Production by Mucor circinelloides Isolate F6-3-12 under Submerged and Solid State Fermentation 167-180 El-Refai, H.A., Mohammed A. Abdel-Naby, Hanan Mostafa, M.A., Magdy A. Amin and Hebat-Allah A. Salem Review Papers CRISPR: Genome -Editing and Beyond 181-189 Sumiyah Rasool, Tufail Hussain, Asima Zehra, Shafat Khan and Shafqat Khan The Vaginal Microbiota in Women Health and Disease: Current Understanding and Future Perspectives - A Review 190-205 Krishna SBN, Stacey L Wilson and Jamila K Adam Biological Actions of PPAR- γ in Health and Disease 206-222 Seema Thakur and Neha Srivastava News Item i - iv Current Trends in Biotechnology and Pharmacy 102 Vol. 11 (2) April103-112 2017, April ISSN 2017, 0973-8916 ISSN 0973-8916 (Print), 2230-7303 (Print), 2230-7303 (Online) (Online) Information to Authors The Current Trends in Biotechnology and Pharmacy is an official international journal of Association of Biotechnology and Pharmacy. It is a peer reviewed quarterly journal dedicated to publish high quality original research articles in biotechnology and pharmacy. The journal will accept contributions from all areas of biotechnology and pharmacy including plant, animal, industrial, microbial, medical, pharmaceutical and analytical biotechnologies, immunology, proteomics, genomics, metabolomics, bioinformatics and different areas in pharmacy such as, pharmaceutics, pharmacology, pharmaceutical chemistry, pharma analysis and pharmacognosy. In addition to the original research papers, review articles in the above mentioned fields will also be considered. Call for papers The Association is inviting original research or review papers and short comunications in any of the above mentioned research areas for publication in Current Trends in Biotechnology and Pharmacy. The manuscripts should be concise, typed in double space in a general format containing a title page with a short running title and the names and addresses of the authors for correspondence followed by Abstract (350 words), 3 – 5 key words, Introduction, Materials and Methods, Results and Discussion, Conclusion, References, followed by the tables, figures and graphs on separate sheets. For quoting references in the text one has to follow the numbering of references in parentheses and full references with appropriate numbers at the end of the text in the same order. References have to be cited in the format below. Mahavadi, S., Rao, R.S.S.K. and Murthy, K.S. (2007). Cross-regulation of VAPC2 receptor internalization by m2 receptors via c-Src-mediated phosphorylation of GRK2. Regulatory Peptides, 139: 109-114. Lehninger, A.L., Nelson, D.L. and Cox, M.M. (2004). Lehninger Principles of Biochemistry, (4th edition), W.H. Freeman & Co., New York, USA, pp. 73-111. Authors have to submit the figures, graphs and tables of the related research paper/article in Adobe Photoshop of the latest version for good illumination and allignment. Authors can submit their papers and articles either to the editor or any of the editorial board members for onward transmission to the editorial office. Members of the editorial board are authorized to accept papers and can recommend for publication after the peer reviewing process. The email address of editorial board members are available in website www.abap.in. For submission of the articles directly, the authors are advised to submit by email to [email protected] or [email protected]. Authors are solely responsible for the data, presentation and conclusions made in their articles/research papers. It is the responsibility of the advertisers for the statements made in the advertisements. No part of the journal can be reproduced without the permission of the editorial office. Current Trends in Biotechnology and Pharmacy 103 Vol. 11 (2) 103-112 April 2017, ISSN 0973-8916 (Print), 2230-7303 (Online) Multiple Parameter Optimization for Maximization of Exopolysaccharide Production from Lactobacillus paraplantarum KM1 by Response Surface Methodology Kanika Sharma, Nivedita Sharma* and Ranjana Sharma Microbiology Research Laboratory, Department of Basic Sciences, Dr. Y. S. Parmar University of Horticulture and Forestry, Nauni, Solan-173230, HP, India *For Correspondence - [email protected] Abstract lactic acid bacteria (LAB) have gained special Statistical experimental design was applied attention. LAB is gram positive bacteria which are to optimize the medium for exopolysaccharides
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