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Swine Pneumonia L-5203 6/98 Swine Pneumonia Bruce Lawhorn* neumonia is an important disease of the lower respiratory tract that impairs animal health and lowers individual and herd Pperformance in swine. “Pneumonia” means inflamma- tion of the lungs. It may be minor, subsiding quickly, or develop into advanced pneumonia. The cause of the lung inflammation and the devel- opment of complications, such as secondary bacterial infection, generally determine how severe pneumonia becomes. Coughing and “thumping”(shallow, rapid breathing) are typical symptoms of pneumonia in swine. As the pneumonia becomes more severe, appe- tite and growth rate decrease, feed is utilized less effi- ciently, hogs may become chronic poor-doers, death may occur and treatment and control costs escalate. Possible causes of pneumonia are bacteria, viruses, parasites, extreme daily temperature fluctuations, chemicals (manure gas), dust and other respiratory tract irritants from the environment. Most of these are in- haled into the lungs. Infectious agents such as certain bacteria may reach the lungs through the blood stream. Parasites reach the lungs by larval migration through blood vessels, tissues and organs. defenses, predisposing them to secondary infection by Atrophic rhinitis and upper respiratory system dis- Pasteurella multocida and other bacteria. The second- ease in swine are discussed in the Extension fact sheet ary infection makes the lower respiratory disease worse L-2193, “Atrophic Rhinitis.” than with the M. hyopneumoniae infection alone. Bacterial Causes The combination of infections, first with M. hyopneumoniae, then with P. multocida, is considered Mycoplasma hyopneumoniae, the pneumonia agent the most frequent form of pneumonia, and is called present in virtually all swine herds, is transmitted from “common swine pneumonia” or enzootic pneumonia. sow to piglets in the farrowing house and from pig to The cost in the United States for enzootic pneumonia pig in nurseries. After transmission, a variable incuba- has been estimated at $4.08 per pig, not including the tion period ensues, followed by nonfatal pneumonia costs of drugs used to treat or reduce the effects of the after the pigs are about 6 to 10 weeks old. M. disease. hyopneumoniae infection weakens the lungs’ normal Actinobacillus pleuropneumoniae (APP) type 1 and 5 cause a very severe form of pneumonia occurring usually between 8 to 26 weeks old. A milder form *Associate Professor and Extension Swine Veterinarian, The Texas caused by APP type 7. All APP types are transmitted A&M University System. through respiratory tract secretions over short dis- Porcine Respiratory Disease Complex (PRDC) tances, such as nose-to-nose contact between adjacent is the term created recently in recognition that PRRS pens of hogs. virus-induced pneumonia predisposes the lungs to a broad range of secondary bacterial or viral infections. Sudden death is common after unobserved symp- Thumping is usually seen after PRRS virus-induced toms or several hours of symptoms such as “thump- pneumonia. Affected swine may die or become chronic ing.” On finding a sudden death from APP infection, a poor-doers and stop growing. producer usually says, “The hogs in this pen were fine yesterday, but this one was found dead this morning!” Pregnant swine infected with PRRS virus often suf- A bloody discharge from the nostrils is usual in hogs fer reproductive loss in the last trimester of gestation. dying from APP infection. Recovered hogs grow slower Farrowing live pigs that do not survive or dead pigs 4 than non-affected penmates and may suffer recurrent to 5 days before the due date are typical symptoms. pneumonia episodes. Infected boars may have low fertility and intermittently shed PRRS virus in semen. Salmonella choleraesuis, a post-weaning disease, initially causes a transient intestinal infection (usually Up to 70 percent of U.S. swine herds are thought to without diarrhea) from oral exposure to contaminated contain PRRS virus-infected swine. It is also an impor- feces, feed, water or environment. A bloodstream in- tant disease worldwide. PRRS is discussed in more fection develops next. It can affect many organs, in- depth in Extension fact sheet L-5137, “Porcine Repro- cluding liver, spleen, brain and lungs. Stressors such ductive and Respiratory Syndrome.” as shipment, moving and mixing with other hogs, poor Swine Influenza virus causes sudden, explosive sorting, overcrowding and outage of feed or water may coughing outbreaks in individual animals or herds, predispose swine to salmonella disease outbreaks. particularly in fall and winter. The “flu” virus spreads Few swine are usually affected, but of those affected, rapidly by air throughout all ages of swine. Coughing many die. Purple discoloration of the ears, snout, jowls subsides by 10 to 11 days after onset. Few swine usu- and abdomen is typical after death, indicating that the ally die, but deaths increase if influenza occurs as part hog died of a severe bloodstream infection as occurs of the PRDC syndrome. Rectal prolapses occur com- with S. choleraesuis infection. monly in swine with severe coughing from “flu.” Lungs can be coinfected with the enzootic pneumo- Death, weight loss and treatment costs in hogs with nia microorganisms (M. hyopneumoniae and P. rectal prolapse are part of the economic loss from an multocida) and APP or S. choleraesuis or both, causing outbreak. Swine recovering from flu may take several severe disease; likewise, lungs can be coinfected with weeks to regain condition, which increases feed costs both APP and S. choleraesuis without enzootic pneu- and days to market. monia infection. Other bacteria such as streptococcal Porcine Respiratory Coronavirus (PRCV) causes species, Bordetella bronchioseptica, Haemophilus pneumonia and is a mutant of the Transmissible Gas- parasuis, Pseudomonas aeruginosa, and Actinomy- troenteritis virus, which causes diarrhea and vomiting ces pyogenes can cause, contribute to or be associated in swine of all ages. Transmitted by air, PRCV is im- with pneumonia lesions in swine. portant as a secondary viral infection as part of the PRDC syndrome. Viral Causes Pseudorabies virus (PRV) is a herpes virus in- Several viruses are important causes of swine pneu- fection (totally unrelated to rabies virus!) that causes monia. Porcine Reproductive Respiratory Syn- central nervous system disease in young pigs, repro- drome (PRRS) is the most common. It is transmitted ductive losses from abortion and pneumonia in older by contact with such body secretions as nasal mucus, swine. Transmission is through contact with virus-con- feces and urine from infected, shedding swine. Al- taining respiratory tract mucus and by PRV dispersed though the PRRS virus generally does not survive for into the air from infected animals. long in the environment, it may survive in chlorinated water for up to 7 days and be transmitted easily in Secondary bacterial complications of PRV-induced contaminated watering systems. It is also transmitted pneumonia slow growth, worsen feed efficiency and in semen. Transmission by air over long distances is cause some deaths. Common in feral swine, PRV in- not considered important. fection is rare in domestic swine in Texas. U.S. domes- tic swine are expected to be PRV-free by the year 2000 The PRRS virus can cause pneumonia in any age of or shortly thereafter. PRV may be a complicating viral swine, but younger pigs may be affected more severely. infection in the PRDC syndrome. Because the lungs’ natural defenses are suppressed after PRRS infection, secondary pneumonia from a wide array of bacteria or viruses is common. Parasitic Causes from chronic coughing. Treatment and control mea- sures costs cause further economic loss. APP may re- Swine internal parasite eggs, such as from round- sult in carcass trim loss because of extensive adhe- worms, survive for many years in soil or manure in sions in the thoracic cavity. lots or solid floor surfaces previously contaminated by infected hogs. Swine confined in these contaminated Diagnosis at Slaughter environments eat microscopic roundworm eggs. Lar- vae then emerge from the eggs, penetrate the intesti- Swine veterinarians routinely inspect market hogs nal tract lining and begin migrating through tissue. at slaughter to identify for their clients the specific dis- About 10 to 14 days after eggs are consumed, larvae ease conditions reducing production efficiency and caus- migrate through the lungs, producing inflammation and ing carcass trim. Although often present in more than coughing. half of all marketed swine, pneumonia usually does not harm pork carcass quality (except for APP pneumonia, Secondary infection with P. multocida or other bac- which causes extensive trim loss). Economic losses from teria can occur, especially if affected swine are exposed pneumonia are predominately from death, reduced simultaneously to adverse weather conditions or other growth rate and inefficient feed conversion. stresses. The effect of pneumonia on production efficiency Lungworm eggs are coughed up, swallowed and may be determined by a veterinarian who combines passed in the feces of infected swine. Earthworms then the production records for growth rates, morbidity, eat the eggs and larvae emerge in this intermediate host. mortality and percent poor-doer hogs along with find- To be infected, a pig must eat earthworms carrying lung- ings from slaughter inspections of lungs and livers (evi- worm larvae. After the earthworms are digested, larvae dence of previous roundworm larval migration migrate to the lungs, through the liver to the lungs is liver where they mature. Mi- “milk spots”or white scars). grating larvae cause lung hemorrhages, and The veterinarian and pro- adults obstruct air- ducer may then develop ways, predisposing treatment and control the swine to infection strategies and monitor from influenza virus, M. progress by follow-up slaugh- hyopneumoniae, or other bacteria. ter inspections, coupled with produc- Heavy lungworm infection causes severe cough- tion records. A veterinarian can also inspect swine that ing. die on the farm after showing pneumonia symptoms. Samples can be submitted to a diagnostic laboratory Other Causes for identification of the cause(s).
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