Wednesday Slide Conference 2008-2009
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PROCEEDINGS DEPARTMENT OF VETERINARY PATHOLOGY WEDNESDAY SLIDE CONFERENCE 2008-2009 ARMED FORCES INSTITUTE OF PATHOLOGY WASHINGTON, D.C. 20306-6000 2009 ML2009 Armed Forces Institute of Pathology Department of Veterinary Pathology WEDNESDAY SLIDE CONFERENCE 2008-2009 100 Cases 100 Histopathology Slides 249 Images PROCEEDINGS PREPARED BY: Todd Bell, DVM Chief Editor: Todd O. Johnson, DVM, Diplomate ACVP Copy Editor: Sean Hahn Layout and Copy Editor: Fran Card WSC Online Management and Design Scott Shaffer ARMED FORCES INSTITUTE OF PATHOLOGY Washington, D.C. 20306-6000 2009 ML2009 i PREFACE The Armed Forces Institute of Pathology, Department of Veterinary Pathology has conducted a weekly slide conference during the resident training year since 12 November 1953. This ever- changing educational endeavor has evolved into the annual Wednesday Slide Conference program in which cases are presented on 25 Wednesdays throughout the academic year and distributed to 135 contributing military and civilian institutions from around the world. Many of these institutions provide structured veterinary pathology resident training programs. During the course of the training year, histopathology slides, digital images, and histories from selected cases are distributed to the participating institutions and to the Department of Veterinary Pathology at the AFIP. Following the conferences, the case diagnoses, comments, and reference listings are posted online to all participants. This study set has been assembled in an effort to make Wednesday Slide Conference materials available to a wider circle of interested pathologists and scientists, and to further the education of veterinary pathologists and residents-in-training. The number of histopathology slides that can be reproduced from smaller lesions requires us to limit the number of participating institutions. This set, composed of 100 cases, 100 histopathology slides and 249 digital images, was assembled from the cases studied during the 2008-2009 conference series. For their participation and permission to use their cases in this study set, we wish to thank each institution, and especially the individuals who prepared and submitted the selected cases. We also wish to give special thanks to the American Veterinary Medical Association and the American College of Veterinary Pathologists, who are co-sponsors of the Registry of Veterinary Pathology. The C.L. Davis Foundation also provides substantial support for the Registry. A special note of appreciation is extended to the reviewers who helped edit and review this year’s individual case summaries: Todd Johnson, Bridget Lewis, Taylor Chance, Dr. Michelle Fleetwood, Sean Hahn, and Fran Card. A final note of thanks goes to the moderators, who unselfishly gave of their time and expertise to help make each conference both enjoyable and educational. Gross images and photomicrographs were submitted by contributing institutions where indicated. Additional photomicrographs were taken by Cary Honnold and Jeremy Bearss. ii Armed Forces Institute of Pathology, Department of Veterinary Pathology WEDNESDAY SLIDE CONFERENCE 2008-2009 Table of Contents Case AFIP No. Slide No. Species Condition/Etiology Tissue Page Conference 1 03 Sept 2008 Moderator: Todd Johnson 1 3102615 N0803234 Elephant seal Toxoplasma gondii Cerebrum; brainstem 1 2 3103740 PA 4596 Macaque Oesophagostomum sp. Colon 4 3 3102365 06-42786 Horse Nephroblastoma Kidney; liver 8 i 4 3102495 03-8246 Pig Actinobacillus suis Lung 11 Conference 2 10 Sept 2008 Moderator: Dr. Sarah Hale 1 3104062 CRL 2008-1 Mouse Corynebacterium bovis Haired skin 13 2 3102251 07-276-3 Mouse Histiocytic sarcoma Liver 15 3 3103042 08014 Macaque Corynebacterium ulcerans Lung 17 4 3103041 08012 African green Autoimmune thyroiditis Thyroid gland 21 monkey Conference 3 17 Sept 2008 Moderator: Jennifer Chapman 1 3103341 AFIP Case 2 Dog Canine distemper virus & Canine Lung 25 adenovirus type 2 2 3103923 47508 Cat Feline systemic reactive Heart 28 angioendotheliomatosis (FSRA) 3 3102492 06-47-18 Rainbow trout Renibacterium salmoninarum Kidney 30 4 3103337 208 0491 Cat Feline ventral abdominal Fibro-adipose tissue and 32 angiosarcoma skeletal muscle Conference 4 01 Oct 2008 Moderator: Taylor Chance 1 3102187 08-0013-03 Horse Seminoma Testicle; spleen 35 2 3104113 06-0534 Cat Myelolipoma Liver 44 3 3104060 CRL 2008-2 Rabbit Eimeria stiedae Liver 45 4 3105527 N0710576 Rat Pituitary gland adenoma Pituitary gland 47 Case AFIP No. Slide No. Species Condition/Etiology Tissue Page Conference 5 8 Oct 2008 Moderator: Marc Mattix 1 3105584 HN 2516 Swan Highly pathogenic avian influenza Cerebrum 53 virus 2 3101429 07-13414 Cat Francisella tularensis Spleen 55 3 3103602 R08-148 Goat Capripox virus Lung 57 4 3102366 ND 1 Bison Mycoplasma bovis Lung 60 Conference 6 22 Oct 2008 Moderator: Dr. Lauren Brinster 1 3106794 DG0802868 Dog Acute respiratory distress syndrome Lung 63 2 3106804 MK 0803123 Macaque Ductular carcinoma in situ (DCIS) Mammary gland 65 3 3094514 36005-7 Mouse Rhabdomyosarcoma, embryonal Skeletal muscle 68 4 3105526 0566-1C Mouse Botryomycosis; Digits, foreleg 71 Conference 7 29 Oct 2008 Moderator: Dale Dunn ii 1 3102259 D07-045891 Hawk West Nile virus Eye 77 2 3102493 067-78252 Cat enrofloxacin induced retinal Eye 80 degeneration 3 3103702 25623-07 Dog Traumatic panopthalmitis Eye 82 4 3065935 07RD0797 Dog Onchocerca sp. Eye 84 Conference 8 05 Nov 2008 Moderator: Dr. Matthew Starost 1 3106959 A8-043171 Ox Malignant catarrhal fever Rete mirabilis: 87 2 3106254 06-17642 Cat Cytauxzoon felis Kidney 90 3 3106209 G08-015746 Chinchilla Listeria monocytogenes Liver 93 4 3105935 07N 929 Dog Trypanosoma cruzi Heart 96 Case AFIP No. Slide No. Species Condition/Etiology Tissue Page Conference 9 12 Nov 2008 Moderator: Dr. Michelle Fleetwood 1 3105831 SDSU-1 Pig Staphlococcus hyicus Haired skin 101 2 3107686 3777-3 Harbor seal Clostridium difficile Intestine 104 3 3106280 5512 Cat Microsporum canis. Haired skin 106 4 3075498 0707051 Dog Cryptococcus neoformans Haired skin 108 Conference 10 03 Dec 2008 Moderator: Dr. Richard Montali 1 3106956 08-956-1 Leopard frog Ranid herpesvirus 1 (RaHV-1) Kidney 111 induced adenocarcinoma 2 3102369 04/3025 D Tasmanian Malignant neuroendocrine neoplasm Haired skin 113 Devil (Tasmanian Devil Facial Tumor Disease) 3 3102636 60136 Horseshoe Shell disease Carpace 115 crab iii 4 3102368 GF-D90-3 Guinea pig Mycobacterium tuberculosis. Mammary gland 119 Conference 11 10 Dec 2008 Moderator: Thomas Steinbach 1 3106179 Cat 3 Cat Renal adenocarcinoma Kidney 123 2 3109441 YN06-328 Macaque Calcinosis circumscripta Haired skin 126 3 3109545 S0709546 Goat Clostridium perfringens type D Colon 128 4 3102509 Case 1 Dog Angiostrongylus vasorum Lung 131 Conference 12 17 Dec 2008 Moderator: Tony Alves 1 3107719 08-22155 Ox Actinobacillus Tongue 137 lignieresii 2 3106267 NIAH-2 Pig Porcine teschovirus (PTV) Spinal cord 140 3 3105581 0806396 Cat Candida albicans Cecum; lymph node 143 4 3106654 V08-03243 Ox Clostridium chauvoei Skeletal muscle 145 Conference 13 07 Jan 2009 Moderator: Dr. Don Schlafer 1 3107596 42029 Ox Cotyledonary hyperplasia Placenta 149 2 3106183 08/14596 Sheep Actinobacillus seminis Epididymis 151 3 3103339 Case 1 Dog Brucella canis Testicle; Epididymis 153 4 2937766 04-26927 Dog Teratoma, favor monodermal Ovary 156 variant Case AFIP No. Slide No. Species Condition/Etiology Tissue Page Conference 14 14 Jan 2009 Moderator: Dr. Bruce Williams 1 3026964 Case 05-2373 Dog Escherichia coli Small intestine 159 2 3106379 G07-120059 Mink Aleutian mink disease Kidney 161 (ADV) 3 3027307 06-34302 Donkey Nutritional myopathy Skeletal muscle 164 4 3096747 07-52047 Dog Sparganum proliferum. Skeletal muscle 166 Conference 15 28 Jan 2009 Moderator: Dr. Michael H. Goldschmidt 1 3102252 T8944-07 Cat Feline acquired skin fragility Haired skin 171 syndrome 2 3103426 05-3388 Dog Warty dyskeratoma Haired skin 174 3 3103391 E28794 2 Cat Merkel cell carcinoma Haired skin 176 4 3102248 H07-0778 Bandicoot Bandicoot papillomatosis Haired skin 179 carcinomatosis virus type 1 Conference 16 04 Feb 2009 Moderator: Dr. Tabitha Viner 1 3115836 08-0165-WSC-2 White-faced Giardia sp. Small intestine 183 iv Ibis 2 3103629 07-18567 Blue heron Eustrongylides sp. Proventriculus 185 3 3102498 08N0017 Fulvous Mycobacterium Liver 188 whistling avium complex duck 4 3102244 BA 652/07 Cat feline idiopathic pulmonary fibrosis Lung 192 (FIPF) Conference 17 11 Feb 2009 Moderator: Dr. Fabio Del Piero 1 3113965 S0 10582 Horse Gastrointestinal stromal tumor Cecum 197 2 3103695 23279-08 Horse Equine multinodular Lung 199 pulmonary fibrosis (EMPF) - Equine Herpesvirus-5 (EHV-5) 3 3103693 63383-02 Horse Cellulosimicrobium cellulans Placenta 201 4 3103232 S07-514.1 Pig Porcine cytomegalovirus (PCMV) Nasal turbinate 203 Case AFIP No. Slide No. Species Condition/Etiology Tissue Page Conference 18 25 Feb 2009 Moderator: Dr. James Raymond 1 3071894 S0704434 Muscovy Duck viral enteritis virus Liver 207 duck 2 3103941 N2008-0451 Northern Dispharynx nasuta Proventriculus 209 bobwhite 3 3107607 122103-07 House Atoxoplasma spp. Liver; spleen 212 sparrow 4 3075580 UNL/VDC 2301-06 Pig Brachyspira hyodysenteriae Colon 215 Conference 19 04 Mar 2009 Moderator: Dr. Amanda Fales-Williams 1 3105599 UFSM-2 Ox Bracken fern (Pteridium Bone marrow 217 v aquilinum) 2 1008-1080 1008-1080 Dog Babesia Blood smear 223 sp. 3 3103707 07H7837A Ox Nutritional polioencephalomalacia Cerebrum 225 (PEM) 4 3093118 Case 1 Dog Uremic pneumonitis Lung 228 Conference 20 11 Mar 2009 Moderator: Dr. Yvonne Schulman 1 3102611 07-1158 Dog Gliomatosis cerebri Brainstem 235 2 3102490 UNAM Case 1 Dog Oligodendroglioma, anaplastic Cerebrum 236 3 3115317 AFIP 08 CASE 1 Cat Feline infectious peritonitis virus Kidney 240 (FIP) 4 3102517 08N0486 Dog Meningioma, chordoid (myxoid) Spinal cord 241 Conference 21 01 Apr 2008 Moderator: Dr. Steven Weisbrode 1 3106281 07-1829 Horse Osteochondrosis Bone 245 2 3103608 APO7-2888 Dog Vitamin D-resistant Bone 247 rickets, Type II 3 3067227 07-5491 Ox Osteopetrosis Bone 252 4 3103199 0120-08 Horse enostosis Bone 253 Case AFIP No. Slide No. Species Condition/Etiology Tissue Page Conference 22 15 Apr 2009 Moderator: Dr.