10/26/2015 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Neurological Disorders and Stroke NINDS Office of Translational Research: New Programs to Rajesh Ranganathan, PhD Support Therapy and Director, Office of Translational Research Device Discovery and NINDS Development
[email protected] July 2015 Number of companies investing in Neuroscience drug discovery 2 1 10/26/2015 Number of companies investing in Neuroscience drug discovery 3 CNS drug discovery portfolio 4 2 10/26/2015 5 6 3 10/26/2015 Ecosystem is pursuing new models – eliminate silos Academia Biotech Pharma Project 1 Project 2 Project 3 Carsten Skarke and Garret A. FitzGerald, Science Translational Medicine April 2010 7 What should NINDS’s role be in this changing climate? 8 4 10/26/2015 Appropriations (Dollars in Thousands) FY 2011 FY 2012 FY 2013 FY2014 FY 2015 NINDS $1,622,003 $1,624,830 $1,533,795 $1,588,904 $1,604,607 NINDS % Base 0.2% -5.6% 3.6% 1.0% Change NIH $30,687,290 $30,860,387 $29,151,462 $30,150,853 $30,311,349 NIH % Change Base 0.6% -5.5% 3.4% 0.5% Average IC increase was 0.31% NINDS and NIMH each received increase of $12.3 M for BRAIN Initiative Funding up to 14 th percentile 9 Total NINDS Extramural Grants Budget 1.6 NINDS Extramural 1.4 1.2 adjusted to 1995 1 dollars 0.8 with ARRA Billions) 0.6 0.4 with ARRA-- 0.2 adjusted to 1995 NINDS Extramural Grant Dollars (in (in Dollars Grant Extramural NINDS dollars 0 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011