Faculty of Medicine (Graduate) Programs, Courses and University Regulations 2013-2014
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Advancing Health Care
Centre universitaire de santé McGill McGill University Health Centre Advancing Health Care Annual Report | 2 0 0 8 - 2 0 0 9 Table of Contents The Best Care for Life 1 Message from the Chairman of the Board of Directors 2 Message from the Director General and CEO 3 Vision, Mission, Values 4 Stats at a Glance 5 2008-2009 Year in Review 6-7 Clinical & Research Firsts 8-9 Advancing Health Care 10-11 Home-based care improving quality of life... 12-13 Nationwide leading pain program providing relief… 14-15 Maintaining quality of life as long as possible… 16-17 Advances in cardiac care paving bright futures… 18-19 Patient care always one step ahead… 20-21 New technology breaking down barriers… 22-23 Research 24-25 Teaching 26-27 The Redevelopment Project 28-29 Foundations 30-31 Auxiliaries & Volunteers 32-33 Awards & Honours 34-35 Board of Directors 36 Financial Results 37-40 Financial Data 41 Statistical Data 42-43 Acknowledgements 44 Annual Report 2008-2009 The Best Care For Life The McGill University Health Centre (MUHC) is a comprehensive academic health institution with an international reputation for excellence in clinical programs, research and teaching. Its partner hospitals are the Montreal Children’s, the Montreal General, the Royal Victoria, the Montreal Neurological Hospital/Institute, the Montreal Chest Institute as well as the Lachine Hospital and Camille- Lefebvre Pavillion. Building on our tradition of medical leadership, the MUHC continues to shape the course of academic medicine by attracting clinical and research authorities from around the world, by training the next generation of medical professionals, and continuing to provide the best care for life to people of all ages. -
About This Issue
ABOUT THIS ISSUE SCHOOL SCHMOOL WAS CREATED IN TIOHTIÀ:KE ("MONTREAL"), UNCEDED INDIGENOUS KANIEN'KEHA:KA (MOHAWK) TERRITORY, WHICH HAS HISTORICALLY BEEN A MEETING AND LIVING SPACE FOR HAUDENOSAUNEE, ABÉNAKI, AND ALGONQUIN PEOPLE. WE ALSO RECOGNIZE THE CONTINUED PRESENCE OF MÉTIS, INNU, AND INUIT FOLK ON THIS LAND. School Schmool is your radical guide to your often unradical school. In 1994, the first editors wrote, “When we say ‘school schmool’ we don’t mean to be dismissive. What we mean is that there are a lot of things going on at university, and school is only one of them.” Though it began as a bi-annual publication that brought together group profiles, articles, and practical resources for social justice, School Schmool is now an ad-free, corporate-free, agenda-with-an-agenda, connecting the McGill, Concordia, and greater Tioh’tia:ke communities.We hope to bridge (and break) the gap between academia and issues outside the classroom by providing a guidebook where students can find information on resources and initiatives taking place in their communities. We strive to feature content that presents radical, anti-oppressive, and intersectional perspectives on current issues, especially works by Queer and/or Trans people, Black and/or Indigenous people, and other people of colour. The theme for this year’s edition is THE TANGIBLE. Over the past few years, it's often felt like everyone was particularly exhausted. Instead of just talking about how shitty things sometimes are, we wanted to offer possibilities for concrete actions, and real ideas for creating radical communities. Sometimes engagement can mean learning how to occupy the McGill administration building (p. -
Inhibits Parathyroid Hormone- Related Peptide Production and Prevents the Development of Malignancy-Associated Hypercalcemia in Vivo
A vitamin D analogue (EB1089) inhibits parathyroid hormone- related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo. M Haq, … , D Goltzman, S A Rabbani J Clin Invest. 1993;91(6):2416-2422. https://doi.org/10.1172/JCI116475. Research Article We have examined the effects of 1,25 dihydroxyvitamin D3 (1,25[OH]2D3) and a low calcemic analogue EB1089 on parathyroid hormone-related peptide (PTHRP) production and on the development of hypercalcemia in Fischer rats implanted with the Leydig cell tumor H-500. Leydig cell tumors were implanted subcutaneously into male Fischer rats, which received constant infusions intraperitoneally of either 1,25(OH)2D3 (50-200 pmol/24 h), EB1089 (50-400 pmol/24 h), or vehicle for up to 4 wk. A control group of animals received similar infusions without tumor implantation. Plasma calcium, plasma levels of immunoreactive iPTHRP, and tumor PTHRP mRNA levels were determined as well as tumor size, animal body weight, and animal survival time. Non-tumor-bearing animals receiving > 50 pmol/24 h of 1,25(OH)2D3 became hypercalcemic, whereas no significant change in plasma calcium was observed in animals receiving < or = 200 pmol/24 h of EB1089. Tumor-bearing animals receiving vehicle alone or > 50 pmol/24 h of 1,25(OH)2D3 became severely hypercalcemic within 15 d. However, animals treated with low dose 1,25(OH)2D3 and all doses of EB1089 maintained near-normal or normal levels of plasma calcium for up to 4 wk. Additionally, reduced levels of tumor PTHRP mRNA and of plasma iPTHRP were observed compared with controls in both vitamin D- and EB1089-treated rats. -
The Search for the "Manchurian Candidate" the Cia and Mind Control
THE SEARCH FOR THE "MANCHURIAN CANDIDATE" THE CIA AND MIND CONTROL John Marks Allen Lane Allen Lane Penguin Books Ltd 17 Grosvenor Gardens London SW1 OBD First published in the U.S.A. by Times Books, a division of Quadrangle/The New York Times Book Co., Inc., and simultaneously in Canada by Fitzhenry & Whiteside Ltd, 1979 First published in Great Britain by Allen Lane 1979 Copyright <£> John Marks, 1979 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission of the copyright owner ISBN 07139 12790 jj Printed in Great Britain by f Thomson Litho Ltd, East Kilbride, Scotland J For Barbara and Daniel AUTHOR'S NOTE This book has grown out of the 16,000 pages of documents that the CIA released to me under the Freedom of Information Act. Without these documents, the best investigative reporting in the world could not have produced a book, and the secrets of CIA mind-control work would have remained buried forever, as the men who knew them had always intended. From the documentary base, I was able to expand my knowledge through interviews and readings in the behavioral sciences. Neverthe- less, the final result is not the whole story of the CIA's attack on the mind. Only a few insiders could have written that, and they choose to remain silent. I have done the best I can to make the book as accurate as possible, but I have been hampered by the refusal of most of the principal characters to be interviewed and by the CIA's destruction in 1973 of many of the key docu- ments. -
Policy and Procedures Manual
McGill Psychology Internship Consortium MPIC Policy and Procedures Manual 2019 - 2020 Blaine Ditto, PhD Director of Clinical Training Michael Sullivan, PhD Internship Director McGill Psychology Internship Consortium Policy and Procedures Manual Table of Contents 1. Introduction.............................................................................................................................. 3 2. Mission and Objectives ................................................................................................................... 3 3. MPIC Member Sites ........................................................................................................................ 3 4. Governance...................................................................................................................................... 4 5. Eligibility .......................................................................................................................................... 5 6. Application Procedures ................................................................................................................... 5 7. Internship Structure......................................................................................................................... 5 8. Internship Funding .......................................................................................................................... 5 9. McGill Psychology – Academic Tracking Software.......................................................................... -
Psychiatry Weekly
PSYCHIATRY WEEKLY March 5, 2018 Call for Applications: 2018 Al-Sumait Prize The prize is to be awarded to individuals or institutions who, through their research projects or initiatives, have made significant advancement in various areas of health on the African Continent. Applications are due June 30, 2018. Please go to www.alsumaitprize.org for full application details. Welcome R1 Residents 2018-2019 On behalf of the Postgraduate Residency Program, we are very happy to announce our newly matched candidates. We matched extremely well and our list not only includes diversity but a record breaking number of candidates from McGill University. Dany Diep University of Saskatchewan Justin Frederick Hall Université de Sherbrooke Sarah Hanafi University of Alberta Laurence Laneuville McGill University Marie-Pier Lecours Université de Montréal Jaclyn Laura Marcovitz McGill University Mohamad Matout McGill University Nima Nahiddi University of Ottawa Catherine Ouellet McGill University Jake Prillo McGill University Gabriel Souza McGill University Carole-Anne Tremblay McGill University Congratulations to our new residents! From the Residency Program Office: Weekly Information Capsule Did You Know the program supports our research track residents by offering them protected time (one half-day every two weeks) starting in the second half of their PGY-1? Upcoming Events Mon, Mar 12 @ 11:00-12:00 (Douglas Institute, Dobell Pavilion, Bowerman Room) Neuroscience for mental health seminars: Dissociable structural and functional hippocampal outputs vis distinct classes of cells in the subiculum with Dr Mark Cembrowski Mon, Mar 13 @ 12:30-14:00 (1001 Decarie Blvd, Conference room, B 08 3019) Child Psychiatry Research Seminar: Bridging cultures and contexts: A multi-method study on risk and protective factors for socio-emotional adjustment among immigrant early adolescents in Italy with Diana Miconi, PhD. -
A Visit to the Redpath Sugar Museum
Number 61/Spring 2017 ELANELAN Ex Libris Association Newsletter www.exlibris.ca INSIDE THIS ISSUE Refined History: A Visit to the Redpath 1 Sugar Museum Refined History: A Visit to the By Tom Eadie President’s Report 2 Redpath Sugar Museum By Elizabeth Ridler By Tom Eadie Ex Libris Biography Project 2 n October 16, 2016, a group By Nancy Williamson of Ex Libris members ELA 2016 Annual Conference Report 3 toured the Redpath Sugar By Barbara Kaye OMuseum located in the Redpath Taking it to the Streets: 4 Sugar Toronto Refinery at 95 Queen’s Summit on the Value of Libraries, Archives Quay East. Richard Feltoe, Curator and Museums [LAMs] in a Changing World and Redpath Corporate Archivist, By Wendy Newman led the tour, which featured his Technology Unmasked: Hoopla 5 knowledgeable explanations, displays By Stan Orlov of artifacts, and an interesting Richard Feltoe, Curator and Redpath Corporate Archivist, above. Enjoying Church Archives, 5 video about sugar production. lunch at Against the Grain, below. one thing leads to another… Redpath Sugar began as the Canada By Doug Robinson Sugar Refining Company, established Celebrating Canada’s Stunning 6 in Montreal in 1854 by John Redpath Urban Library Branches (1796–1869). Born in Scotland and By Barbara Clubb orphaned when young, Redpath Stratford Festival Archives 6 rose from obscurity to eminence. An By Judy Ginsler apprentice stonemason, he immigrated to Canada at the age of 20. Over time A Memory of Marie F. Zielinska (1921–2016) 7 Prepared by Ralph W. Manning, Redpath became a building contractor with contributions from Irena Bell, involved in the construction of many Frank Kirkwood, Marianne Scott, well-known Montreal buildings, and Jean (Guy) Weerasinghe including Notre-Dame Basilica, the development of sugar production and Library Treasures of Britain: 8 Montreal General Hospital, and the refining in the context of social issues The Royal College of Surgeons Bank of Montreal headquarters. -
Reversal of Hypercalcemia with the Vitamin D Analogue EB1089 in a Human Model of Squamous Cancer1
[CANCER RESEARCH 59, 3325–3328, July 15, 1999] Advances in Brief Reversal of Hypercalcemia with the Vitamin D Analogue EB1089 in a Human Model of Squamous Cancer1 Khadija El Abdaimi, Vasiliou Papavasiliou, Shafaat A. Rabbani, Johng S. Rhim, David Goltzman, and Richard Kremer2 Departments of Medicine, McGill University and Royal Victoria Hospital, Montreal, Quebec H3A 1A1, Canada [K. E. A., S. A. R., D. G., R. K.], and Laboratory of Molecular Oncology, National Cancer Institute, Frederick, Maryland 21702 [J. S. R.] Abstract demonstrated that 1,25(OH)2D3 blocks PTHRP production (10). Using a multistep model of epithelial cell carcinogenesis, we EB1089, an analogue of 1,25 dihydroxyvitamin D with low calcemic demonstrated that the progression from the normal to the malignant activity is a potent inhibitor of parathyroid hormone-related peptide phenotype was characterized by a partial resistance to the inhibi- (PTHRP) production in vitro. The purpose of the present study was to determine whether EB1089 could reverse established hypercalcemia in tory effect by 1,25(OH)2D3 requiring 10- to 100-fold higher con- BALB C nude mice implanted s.c. with a human epithelial cancer centrations of 1,25(OH)2D3 to achieve the same effects (11, 12). previously shown to produce high levels of PTHRP in vitro. Total To develop alternative strategies to block PTHRP production in plasma calcium was monitored before and after tumor development vitro and in vivo, several 1,25(OH)2D3 analogues—known to have and increased steadily when the tumor reached >0.5 cm3. When total low calcemic activities yet to retain strong antiproliferative effects calcium was >2.85 mmol/liter, animals were treated with a constant on keratinocytes in vitro (13)—were tested. -
Bisphosphonates for Treatment of Osteoporosis Expected Benefts, Potential Harms, and Drug Holidays
Clinical Review Bisphosphonates for treatment of osteoporosis Expected benefts, potential harms, and drug holidays Jacques P. Brown MD Suzanne Morin MD MSc William Leslie MD Alexandra Papaioannou MD Angela M. Cheung MD PhD Kenneth S. Davison PhD David Goltzman MD David Arthur Hanley MD Anthony Hodsman MD Robert Josse MD Algis Jovaisas MD Angela Juby MD Stephanie Kaiser MD Andrew Karaplis MD David Kendler MD Aliya Khan MD Daniel Ngui MD Wojciech Olszynski MD PhD Louis-Georges Ste-Marie MD Jonathan Adachi MD Abstract Objective To outline the effcacy and risks of bisphosphonate therapy for the management of osteoporosis and describe which patients might be eligible for bisphosphonate “drug holiday.” Quality of evidence MEDLINE (PubMed, through December 31, 2012) was used to identify relevant publications for inclusion. Most of the evidence cited is level II evidence (non-randomized, cohort, and other comparisons trials). Main message The antifracture effcacy of approved frst-line bisphosphonates has been proven in randomized controlled clinical trials. However, with more extensive and prolonged clinical use of bisphosphonates, associations have been reported between their administration and the occurrence of rare, but serious, adverse events. Osteonecrosis of the jaw and atypical subtrochanteric and diaphyseal femur fractures might be related to the use of bisphosphonates in osteoporosis, but they are exceedingly rare and they often occur with other comorbidities or concomitant medication use. Drug holidays should only be considered in low-risk patients and in select patients at moderate risk of fracture after 3 to 5 years of therapy. Conclusion When bisphosphonates are prescribed to patients at high risk of fracture, their antifracture benefts considerably outweigh their potential for harm. -
Vital Signs Vital Signs
VITALVITAL SIGNSSIGNS THE NEWSLETTER OF MCGILL UNIVERSITY DEPARTMENT OF MEDICINE Volume 8. Number 1 March 2013 THE EXTERNAL development of a recruitment strategy. We are encouraged to recruit more clinician-scientists REVIEW OF THE and to consider a research-residency track in the DEPARTMENT OF core training program. The availability of FRQS funding and remuneration recherche was MEDICINE identified as a major advantage for the support of the research enterprise but the dilemma posed by the lack of a career track following the cessation Dr. James Martin, Interim Chair and Executive of remuneration recherche was also identified. Vice-Chair, Faculty Affairs, Department of Support for tenured positions on coming off Medicine remuneration recherche was strongly advocated. The teaching programs were judged to be strong At the behest of the Dean an external review of although concerns were expressed that the the Department was held on November 26th and program leaders were not necessarily sufficiently 27th, 2012 as part of the process of the search recompensed for their time and efforts. The many for a new Department Chair. The review workshops for enhancing teaching skills by the committee was comprised of Drs. Graydon Faculty have not been sufficiently availed of by Meneilly (University of British Columbia), Phil clinical teachers. Junior faculty or those of us Wells (University of Ottawa) and David Goltzman. whose evaluations are not strong are encouraged Many of the Department members on all sites to take advantage of the opportunities to upgrade participated in the process, providing frank our teaching skills. Many complimentary remarks feedback to the reviewers. -
Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D
BASIC RESEARCH www.jasn.org Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D † ‡ | Loan Nguyen-Yamamoto,* Andrew C. Karaplis, Rene St–Arnaud,* § and David Goltzman* Departments of *Medicine, ‡Surgery, and §Human Genetics, and †Department of Medicine, Sir Mortimer B. Davis Jewish General Hospital, McGill University, Montreal, Canada; and |Research Centre, Shriners Hospital for Children, Montreal, Canada ABSTRACT Circulating levels of fibroblast growth factor 23 (FGF23) increase during the early stages of kidney disease, but the underlying mechanism remains incompletely characterized. We investigated the role of vitamin D metabolites in regulating intact FGF23 production in genetically modified mice without and with adenine- induced uremia. Exogenous calcitriol (1,25-dihydroxyvitamin D) and high circulating levels of calcidiol (25-hydroxyvitamin D) each increased serum FGF23 levels in wild-type mice and in mice with global deficiency of the Cyp27b1 gene encoding 25-hydroxyvitamin D 1-a-hydroxylase, which produces 1,25- hydroxyvitamin D. Compared with wild-type mice, normal, or uremic mice lacking Cyp27b1 had lower levels of serum FGF23, despite having high concentrations of parathyroid hormone, but administration of exogenous 1,25-dihydroxyvitamin D increased FGF23 levels. Furthermore, raising serum calcium levels in Cyp27b1-depleted mice directly increased FGF23 levels and indirectly enhanced the action of ambient vitamin Dmetabolitesvia the vitamin D receptor. In chromatin immunoprecipitation assays, 25-hydroxyvitamin D pro- moted binding of the vitamin D receptor and retinoid X receptor to the promoters of osteoblastic target genes. Conditional osteoblastic deletion of Cyp27b1 caused lower serum FGF23 levels, despite normal circulating levels of vitamin D metabolites. -
Annual Report 2020-2021
ANNEX 2 MCGILL UNIVERSITY HEALTH CENTRE USERS’ / PATIENTS’ COMMITTEE (MUHC UC/PC) 2020-2021 ANNUAL REPORT TABLE OF CONTENTS PAGE 1. INFORMATION ABOUT THE INSTITUTION 3 2. MESSAGE FROM THE CO-CHAIRS 4 3. PRIORITIES AND ACHIEVEMENTS OF THE PAST YEAR 5 4. THE COMMITTEE AND ITS MEMBERS 6 5. CONTACT INFORMATION 7 6. ACTIVITIES OF THE MUHC UC/PC 8 7. MUHC UC/PC MEETINGS 11 8. COLLABORATION WITH THE OTHER ACTORS IN COMPLAINT EXAMINATION SYSTEM 11 9. GOALS ESTABLISHED FOR NEXT YEAR 13 10. CONCLUSION (ISSUES, RECOMMENDATIONS AND PROJECTS 13 11. FINANCIAL REPORT 14 12. ACTIVITIES OF THE RESIDENTS’ COMMITTEE OF THE CAMILLE-LEFEBVRE PAVILION 14 2 1. INFORMATION ABOUT THE INSTITUTION The McGill University Health Centre (MUHC) is a non-merged institution. The MUHC is comprised of the: Allan Memorial Institute - Allan Lachine Hospital and Camille Lefebvre Pavilion - Lachine Montreal General Hospital - MGH Montreal Neurological Institute and Hospital - Neuro MUHC Reproductive Centre And the Glen Site: Cedars Cancer Centre - CCC McGill Academic Eye Centre - MAEC Montreal Chest Institute - MCI Montreal Children’s Hospital - MCH Research Institute - RI Royal Victoria Hospital - RVH 3 2. MESSAGE FROM THE CO-CHAIRS The year 2020-2021 will long be remembered by MUHC patients and the MUHC Patients' Committee. The pandemic has disrupted the MUHC's normal operations and its ability to provide services to the population. The Patients' Committee would like to sincerely thank all MUHC staff and administration for their determination and resilience during this exceptional year. Despite the difficult context, the Patients' Committee has continued to respond to the increased requests from patients who have been experiencing multiple difficulties in obtaining appointments, in contacting clinics, in dealing with surgery postponements, in communicating with or visiting loved ones who were hospitalized, in obtaining news on their health status, and in fulfilling their duties as caregivers for Camille-Lefebvre residents.