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Faits Saillants De La Recherche En Gastroentérologie Par Les Canadiens Milestones of Research in Gastroenterology by Canadians

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Faits Saillants De La Recherche En Gastroentérologie Par Les Canadiens Milestones of Research in Gastroenterology by Canadians Milestones of Research in Gastroenterology by Canadians Ivan T Beck. Queen’s University. Kingston. ON. Awardees of CAG Awardees of CAG Gastric Physiology Hormones Stem cells, Iron, Motility Hepatology Ivan T Beck Lecturers Richard McKenna lecturers Alexis St.Martin William Beamont Frederick G Banting and Charles H Best Charles Phillippe Leblond Aron M Rappaport 1904 - 1992 see poster 1794-1881 1785-1853 1891-1941 1899 -1978 1910 - Dr. Carl A Goresky (by Dr.J.J.Connon ) 1996 “Captions of History of CAG” Research subject Treating a gun Dr. Claude C Roy 1997 Extract insulin in 1921 from Dr Leblond obtained his MD at the Université de Paris (1934) Born in Bukowina ( a duchy of the Austrio-Hungarian whose gastric shot wound, Dr. Joseph J Connon 1998 DSc at Sorbonne(1945) and PhD at McGill( 1946) monarchy). MD 1929 Prague. Surgical training Berlin fistula allowed Dr. W. Beamont dog pancreas and Paris. During World War II, surgeon in Bucharest, Dr. Eldon A Shaffer 1999 for the study of created a gastric Banting, a practicing surgeon theorized Dr. Noel C Williams 2000 fistula. In 1946 he initiated the method of radioautography,which Rumania. Came to Canada and joined Dr. C.H Best as gastric secretory that ligating the pancreatic duct, the Dr. Grant W Thompson 2001 function. He carried out enabled him to trace the activity of movement of substances Assistant in the Department of Physiology in 1946. Ph.D. exocrine function will atrophy and in vivo. Using this method he established that cells are 1952. Professor, Physiology, University of Toronto 1962 Dr. Jenny E L Heathcote 2002 238 studies on endocrine function will remain intact. Research excellence lecturers the stomach of continuously active. Dr. Richard H Hunt 2003 St. Martin in 4 In 1948 he demonstrated constant Dr Rappaport developed a microcirculatory model Dr. Richard J Hamilton 2004 Allowed to work in Dr. J J R MacLeod’s locations in 8 renewal of intestinal epithelium and describing the hepatic acinus. This allowed him to Physiology Department in Toronto Dr. Leslie S Valberg, 1982 years that cells are moving from crypt to establish a new concept of functional liver zones Dr. John Bienenstock, 1983 during the summer. villus. applicable to pathology. Blood flows to the acinus Dr. Gordon G Forstner, 1984 Coureur de bois Surgeon and Physiologist In 1974 he demonstrated that four through zone 1 and exits in zone 3. Best, recently graduated from Chemistry 1948 al l cells move up from cr ypt Dr. Joseph S Davison, main cell types: columnar, Paneth, 1985 Injured June 6 1822 Fort Mackinac and still a medical student joined for the Zone 1 is the first to receive nutrients and Kopelman award lecturer Dr. Jean A Morisset, 1986 mucous and entero-endocrine all summer. originate from crypt cells toxins. Last to die of poor circulation. It is Dr. John C Brown, 1987 Together they established that: the main area of oxidative metabolism. It Dr. David Withcomb 2003 Dr. Edwin E Daniel 1988 From atrophic pancreas they succeeded Gastric content is acid. is most sensitive to toxins. Dr. Ivan T Beck, 1989 to extract insulin Food put into the stomach is digested & disappears. The crypt base cell is multi-potential Zone 2 intermediary Dr. Hector Orrego, 1990 Zone 3 is first to experience ischemic Based on description by Gastric secretion outside stomach digests food. Picture of Dr. Banting and Best at top of and is the stem cell of the epithelium D r. R a p pa port , t hi s i s a Dr. Nicholas Diamant, 1991 necrosis fibrosis and accumulation of fat water color prep ared by Picture received from Rare book Library University of Toronto Physiology building with experimental dog 1957 four different cells originate “Dept.of Art as Applied to Dr. Grant D Gall, 1992 from crypts Med ici ne” ; U.of Toro nto Schematic rep resentation of liver acinus Education excellence lecturers Dr. Alan B.R. Thomson, 1993 Dr. Claude C. Roy, 1994 Dr. Claude C Roy 2003 Dr. Stephen M Collins, 1995 Dr. Ivan T Beck 2004 Dr. Khursheed N. Jeejeebhoy, 1996 Dr. Gordon R. Greenberg, 1997 Dr. John L Wallace 1998 Dr. Philip M. Sherman, 1999 Dr. William G. Paterson, 2000 Dr. Mary H Perdue, 2001 Dr. Jan D Huizinga, 2002 Boris Petrovitch Babkin John C Brown Leslie S Valberg Carl A Goresky Dr. Daniel Menard 2003 (1877-1950) 1938--- 1929-1998 1932-1996 Dr. Jonathan B Meddings 2004 Dr.Boris Babkin was initiated in the field of physiology Awardees of CASL Dr Valberg was born in Saskatchewan. MD degree Born in Alberta. Son of a physician. Entered by Dr.Pavel Pavlov. Dr Babkin held prestigious posts Born in England. Ph.D.:1964 at University at Queen’s University, Kingston, Ontario in 1954. McGill University at age 18 and graduated in Russia. He was imprisoned and expelled by the of Newcastle upon Tyne. D.Sc.1977 at same Postgraduate training with Dr Sydney Truelove with MDCM at age 22. Post-graduate work at Soviet Regime in 1922 University. Came to Canada in 1965 to join the University of British Columbia at Oxford. He joined Queen’s in 1960. Professor of John’s Hopkins with Dr Francis Chinard, where Medicine in 1972. An outstanding clinician,teacher he became interested in utilizing the multiple After several posts in England he came to Canada and and organizer, he was asked to join the University indicator dilution formula in research. Young Investigator Lecturers joined Dalhousie University (Halifax) in1924, and McGill Dr Brown extracted Motilin from hog upper of Western Ontario (London, Ontario.) as Chair of the University (Montreal) in 1928 intestine. Determined its peptide structure Department of Medicine and later Dean. Dr. Philip M Sherman 1993 in 1973. Described amino-acid differences At McGill he refined this mathematical formula His main interest, however, remained research. and developed his experimental technique. He Dr. John L Wallace 1994 Dr Babkin studied the function of salivary, gastric and of human motilin in 1974. Dr Pierre Poitras Professor of Medicine, McGill. Gold medallist lecturers pancreatic glands. His aim was to identify the inter - Université de Montréal found that motilin injected different tracers simultaneously into Dr. Jonathan B Meddings 1995 Dr Valberg’s work in iron metabolism achieved world recognition. He established a Brilliant physician and teacher. action by which individual glands elaborate a variety stimulates the onset of the inter-digestive the hepatic artery and analyzed them separately Dr. Stephen J Vanner 1996 Professor of physiology method of iron absorption utilizing urinary cobalt excretion as a marker. Several Admired by his patients and Dr. Jean- Pierre Benhamou 1983 of secretory products. His concept of integrating neural myoelectric complex and controls intestinal in timed samples Dr. Herbert Y Gaisano University of British Columbia studies clarified the relation between iron and other metals: manganese, zinc, copper peers. His passion, however 1997 and hormonal interactions was unique at his time. motility in dogs and humans in the venous blood. Dr. Robert Purcell 1984 Dr. Gervais J H Tougas 1998 tin and cadmium. remained research. This provided whole Dr. Rudi Schmid 1985 Dr. Keith A Sharkey 1999 His work is the basis of today's theory of gut organ approach to Dr. Sheila Sherlock 1986 In 1970 Dr Brown extracted Gastric Inhibitory Polypeptide an inhibitory factor His main achievement was on hemochromatosis. Dr. Paul Kubes 2000 brain interaction cellular metabolism, Dr. Aron M Rappaport 1987 Portrait obtained from Mc Gill university from partially purified hog CCK. In London (ON) he collected over 170 homozygotes. Dr. Derek McKay 2001 His method has been accepted with data on capillary Dr. Carl A Goresky 1988 Based on this group he described the natural history by other investigators to study permeation,cellular Dr. Wallace K MacNaughton 2002 He determined its amino acid structure in 1971, and found that it inhibits gastric Dr. Hyman J Zimmerman 1989 of the disease and compared methods of identifying cellular metabolism of other transport and reaction Dr. Young –In J Kim 2003 His greatest strength was his enthusiastic mentoring of many physiologists, secretion and stimulates insulin release A study, demonstrating diff erences in Dr. Baruch S Blumberg 1990 asymptomatic patients by comparing the value of whole organs. kinetics of multiple hepatic outflow of red cells,sucrose and Dr. Nathalie Vergnolle 2004 physicians and surgeons, who later established their own reputation glucose while investigating how glucose Dr. Hector Orrego 1991 genetic testing, iron studies and morphology. Liver biopsy of hemochromatosis substances is handled by the liver. Dr. Roger Williams 1992 Dr. Telfer B Reynolds 1993 Dr. James M Phillips 1994 Dr. Diane W Cox 1995 Visiting research professors Dr. Laurence M Blendis 1996 Dr. Lawrie W Powell 1997 Dr. Khursheed N Jeejeebhoy 1981 Dr. William Wall 1998 Dr. Claude C Roy 1982 Dr. Juan Rodes 1999 Dr. Eldon A Shaffer 1983 Dr. Lorne D Tyrrell 2000 Dr. Richard J Hamilton 1984 Dr. Jay Hoofnagle 2001 Dr. Richard H Hunt 1986 Hans Selye Dr Jean A Morisset Edwin E Daniel Andrew Sass-Kortsak Dr. Pierre-Michel Huet 2002 Dr. Laurence M Blendis 1987 1907 - 1982 1940 - 1925 - 1916 - 1986 Dr. Roger Butterworth 2003 Dr. James A Barrowman 1989 Dr.Selye was born in the Austrian - Hungarian Monarchy. Dr Andrew Sass-Kortsak was born in Hungary. Dr. Jenny E L Heathcote 2004 Born in Chattanooga, Tennessee. USA. Dr. E Jenny L Heathcote 1990 His father was a Hungarian surgeon, mother was Austrian. Born: Baie Comeau, Quebec. Dr Morisset was Ph.D. 1952 University of Utah. Came to Obtained his MD degree in 1940 and certificate in Dr. Noel C Williams 1991 He graduated in Medicine in Prague (1929)and Ph.D.(1931).
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