Author Manuscript Published OnlineFirst on September 5, 2019; DOI: 10.1158/0008-5472.CAN-19-0198 Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma Jinkyu Jung1,#, Ying Zhang2, Orieta Celiku1, Wei Zhang1, Hua Song1, Brian J. Williams3, Amber J. Giles1, Jeremy N. Rich4, Roger Abounader2, Mark R. Gilbert1, and Deric M. Park1,5,# 1Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA 2Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, USA 3Department of Neurosurgery, University of Louisville, Louisville, KY, USA 4Department of Medicine, Division of Regenerative Medicine, University of California - San Diego School of Medicine, La Jolla, California, USA 5Neuro-Oncology Section, Department of Neurology, and the Committee on Clinical Pharmacology and Pharmacogenomics, The University of Chicago, Chicago, USA Abstract word number: 171 Number of figures: 7 Running title: Mitochondrial NIX Maintains Hypoxic Niche of Glioblastoma # Correspondence should be addressed to D.M.P. or J.J. Deric M. Park, M.D. Department of Neurology, The University of Chicago, Chicago, IL 60637 Phone: +1-773-702-3510 Email:
[email protected] Jinkyu Jung, Ph.D. Neuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 Phone: +1-301-760-7051 Email:
[email protected] Conflict of interest: The authors have declared that no conflict of interest exists. 1 Downloaded from cancerres.aacrjournals.org on September 23, 2021. © 2019 American Association for Cancer Research. Author Manuscript Published OnlineFirst on September 5, 2019; DOI: 10.1158/0008-5472.CAN-19-0198 Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited.