Prevention of Hepatitis C in Women
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Shigella Infection - Factsheet
Shigella Infection - Factsheet What is Shigellosis? How common is it? Shigellosis is an infectious disease caused by a group of bacteria (germs) called Shigella. It’s also known as bacillary dysentery. There are four main types of Shigella germ but Shigella sonnei is by far the commonest cause of this illness in the UK. Most cases of the other types are usually brought in from abroad. How is Shigellosis caught? Shigella is not known to be found in animals so it always passes from one infected person to the next, though the route may be indirect. Here are some possible ways in which you can get infected: • Shigella germs are present in the stools of infected persons while they are ill and for a week or two afterwards. Most Shigella infections are the result of germs passing from stools or soiled fingers of one person to the mouth of another person. This happens when basic hygiene and hand washing habits are inadequate, such as in young toddlers who are not yet fully toilet trained. Family members and playmates of such children are at high risk of becoming infected. • Shigellosis can be acquired from someone who is infected but has no symptoms. • Shigellosis may be picked up from eating contaminated food, which may look and smell normal. Food may become contaminated by infected food handlers who do not wash their hands properly after using the toilet. They should report sick and avoid handling food if they are ill but they may not always have symptoms. • Vegetables can become contaminated if they are harvested from a field with sewage in it. -
E. Coli: Serotypes Other Than O157:H7 Prepared by Zuber Mulla, BA, MSPH DOH, Regional Epidemiologist
E. coli: Serotypes other than O157:H7 Prepared by Zuber Mulla, BA, MSPH DOH, Regional Epidemiologist Escherichia coli (E. coli) is the predominant nonpathogenic facultative flora of the human intestine [1]. However, several strains of E. coli have developed the ability to cause disease in humans. Strains of E. coli that cause gastroenteritis in humans can be grouped into six categories: enteroaggregative (EAEC), enterohemorrhagic (EHEC), enteroinvasive (EIEC), enteropathogenic (EPEC), enterotoxigenic (ETEC), and diffuse adherent (DAEC). Pathogenic E. coli are serotyped on the basis of their O (somatic), H (flagellar), and K (capsular) surface antigen profiles [1]. Each of the six categories listed above has a different pathogenesis and comprises a different set of O:H serotypes [2]. In Florida, gastrointestinal illness caused by E. coli is reportable in two categories: E. coli O157:H7 or E. coli, other. In 1997, 52 cases of E. coli O157:H7 and seven cases of E. coli, other (known serotype), were reported to the Florida Department of Health [3]. Enteroaggregative E. coli (EAEC) - EAEC has been associated with persistent diarrhea (>14 days), especially in developing countries [1]. The diarrhea is usually watery, secretory and not accompanied by fever or vomiting [1]. The incubation period has been estimated to be 20 to 48 hours [2]. Enterohemorrhagic E. coli (EHEC) - While the main EHEC serotype is E. coli O157:H7 (see July 24, 1998, issue of the “Epi Update”), other serotypes such as O111:H8 and O104:H21 are diarrheogenic in humans [2]. EHEC excrete potent toxins called verotoxins or Shiga toxins (so called because of their close resemblance to the Shiga toxin of Shigella dysenteriae 1This group of organisms is often referred to as Shiga toxin-producing E. -
Zoonotic Diseases Fact Sheet
ZOONOTIC DISEASES FACT SHEET s e ion ecie s n t n p is ms n e e s tio s g s m to a a o u t Rang s p t tme to e th n s n m c a s a ra y a re ho Di P Ge Ho T S Incub F T P Brucella (B. Infected animals Skin or mucous membrane High and protracted (extended) fever. 1-15 weeks Most commonly Antibiotic melitensis, B. (swine, cattle, goats, contact with infected Infection affects bone, heart, reported U.S. combination: abortus, B. suis, B. sheep, dogs) animals, their blood, tissue, gallbladder, kidney, spleen, and laboratory-associated streptomycina, Brucellosis* Bacteria canis ) and other body fluids causes highly disseminated lesions bacterial infection in tetracycline, and and abscess man sulfonamides Salmonella (S. Domestic (dogs, cats, Direct contact as well as Mild gastroenteritiis (diarrhea) to high 6 hours to 3 Fatality rate of 5-10% Antibiotic cholera-suis, S. monkeys, rodents, indirect consumption fever, severe headache, and spleen days combination: enteriditis, S. labor-atory rodents, (eggs, food vehicles using enlargement. May lead to focal chloramphenicol, typhymurium, S. rep-tiles [especially eggs, etc.). Human to infection in any organ or tissue of the neomycin, ampicillin Salmonellosis Bacteria typhi) turtles], chickens and human transmission also body) fish) and herd animals possible (cattle, chickens, pigs) All Shigella species Captive non-human Oral-fecal route Ranges from asymptomatic carrier to Varies by Highly infective. Low Intravenous fluids primates severe bacillary dysentery with high species. 16 number of organisms and electrolytes, fevers, weakness, severe abdominal hours to 7 capable of causing Antibiotics: ampicillin, cramps, prostration, edema of the days. -
Communicable Diseases Communiqué DECEMBER 2012, Vol
Communicable Diseases Communiqué DECEMBER 2012, Vol. 11(12) CONTENTS Shigellosis outbreak 1 Rabies 2 Trypanosomiasis 3 Influenza 4 Beyond our Borders 5 Shigellosis Outbreak in Nelson Mandela Bay Health District, Eastern Cape Province An NHLS pathologist based in Port Elizabeth (Nelson isolated from both blood culture and stool in a 2- Mandela Bay Health District, Eastern Cape Province) year-old child with severe bloody diarrhoea and noticed a sudden marked increase in the number of fever. There has been one fatal case to date (a 76- shigellosis cases at a provincial public hospital and year-old female who presented with bloody primary health care clinic in the district during the diarrhoea and dehydration). last week of November 2012. This was reported to the National Outbreak Unit (NICD-NHLS and Of the Shigella spp. isolates referred to the Centre National Department of Health) which prompted for Enteric Diseases (NICD-NHLS) for further further investigation. characterisation, 11 have been tested to date and all are Shigella flexneri 1b. Twelve laboratory-confirmed cases of S. flexneri had been reported between 23 and 26 November Humans and other large primates are the only 2012; by 3 December 2012 the number of natural reservoirs of Shigella spp. Person-to-person laboratory-confirmed cases had risen to 24 (21 of spread is the commonest mode of transmission, but whom had severe disease necessitating hospital infection and outbreaks can also be caused by admission). Although cases were identified in both contaminated food or water. Shigellosis is one of public and private healthcare facilities in the district, the most communicable of the bacterial causes of the majority were resident in the Kwazakhele area diarrhoea, since a low dose of organisms readily and shared no other common risk exposures. -
Enteric Infections Due to Campylobacter, Yersinia, Salmonella, and Shigella*
Bulletin of the World Health Organization, 58 (4): 519-537 (1980) Enteric infections due to Campylobacter, Yersinia, Salmonella, and Shigella* WHO SCIENTIFIC WORKING GROUP1 This report reviews the available information on the clinical features, pathogenesis, bacteriology, and epidemiology ofCampylobacter jejuni and Yersinia enterocolitica, both of which have recently been recognized as important causes of enteric infection. In the fields of salmonellosis and shigellosis, important new epidemiological and relatedfindings that have implications for the control of these infections are described. Priority research activities in each ofthese areas are outlined. Of the organisms discussed in this article, Campylobacter jejuni and Yersinia entero- colitica have only recently been recognized as important causes of enteric infection, and accordingly the available knowledge on these pathogens is reviewed in full. In the better- known fields of salmonellosis (including typhoid fever) and shigellosis, the review is limited to new and important information that has implications for their control.! REVIEW OF RECENT KNOWLEDGE Campylobacterjejuni In the last few years, C.jejuni (previously called 'related vibrios') has emerged as an important cause of acute diarrhoeal disease. Although this organism was suspected of being a cause ofacute enteritis in man as early as 1954, it was not until 1972, in Belgium, that it was first shown to be a relatively common cause of diarrhoea. Since then, workers in Australia, Canada, Netherlands, Sweden, United Kingdom, and the United States of America have reported its isolation from 5-14% of diarrhoea cases and less than 1 % of asymptomatic persons. Most of the information given below is based on conclusions drawn from these studies in developed countries. -
Unusual Presentation of Shigellosis: Acute Perforated Appendicitis And
Case Report 45 Unusual Presentation of Shigellosis: Acute Perforated Appendicitis and Peritonitis Gülsüm İclal Bayhan1, Gönül Tanır1, Haşim Ata Maden2, Şengül Özkan3 1Pediatric Infection Clinic, Dr. Sami Ulus Gynecology, Child Care and Treatment Training and Research Hospital, Ankara, Turkey 2Department of Pediatric Surgery, Dr. Sami Ulus Gynecology, Child Care and Treatment Training and Research Hospital, Ankara, Turkey 3Microbiology Clinic. Dr. Sami Ulus Gynecology, Child Care and Treatment Training and Research Hospital, Ankara, Turkey Abstract Shigella spp. is one of the most common agents that cause bacterial diarrhea and dysentery in developing coun- tries. Clinical presentation of shigellosis may vary over a wide spectrum from mild diarrhea to severe dysentery. We report the case of 5.5-year-old previously healthy boy, who presented to our clinic with abdominal pain, vomiting, and constipation. On examination, we noticed abdominal tenderness with guarding at the right lower quadrant. With the diagnosis of acute appendicitis, open appendectomy was performed. Exploration of the abdominal cavity revealed perforated appendicitis and generalized peritonitis. Shigella sonnei was isolated from the peritoneal fluid culture. The patient completely recovered without any complications. Surgical complications, including appendicitis, could have developed during shigellosis. There are few reported cases of perforated appendicitis associated with Shigella. Prompt surgical intervention can be beneficial to prevent morbidity and mortality if it is performed early in the course of the disease. (J Pediatr Inf 2015; 9: 45-8) Keywords: Shigella spp., acute appendicitis, peritonitis, surgical complication Introduction intestinal and extra-intestinal complications. There are few reported cases of perforated Shigella spp., a group of Gram-negative, appendicitis complicated with peritonitis due to Received: 04.10.2013 Accepted: 03.02.2014 small, non-motile, non-spore forming, and rod- Shigella spp. -
Bacillary Dysentery
Bacillary dysentery by Sudhir Chandra Pal uring the first half of 1984, a infectious dose. It requires only 10 to drome and leukaemoid reactions were severe epidemic of bacillary 100 shigella bacteria to produce dys also reported. dysentery swept through the entery, whereas one million to ten Similar epidemics due to the districts of West Bengal and a few million germs may need to be swal multiple-drug-resistant S. shigae have other eastern Indian States, affecting lowed to cause cholera. also occurred in Somalia (1976), three over 350,000 people and leaving By 1920, dysentery due to the most villages in South India (1976), Sri about 3,500, mostly children, dead. It virulent variety, the Shiga bacillus, Lanka (1978-80), Central Africa was like a nightmare as the disease had almost disappeared from Europe (1980-82), Eastern India, Nepal, Bhu stubbornly refused to respond to con and North America. However, it con tan and the Maldives (1984) and Bur ventional treatment, and its galloping tinued to be reported from the de ma (1984-85). The pattern was more spread could not be contained by all veloping countries in the form of local or less the same everywhere. The available public health measures. ised outbreaks. During the late sixties, disease spread with terrific speed in People became confused and panicky, Shiga's bacillus reappeared with a big spite of all available public health not knowing what to do. bang as the main culprit of a series of measures, attacking over 10 per cent Bacillary dysentery, characterised devastating epidemics of dysentery of the population and killing between by frequent passage of blood and in a number of countries in Latin two and 10 per cent even of the mucus in the stools accompanied by America, Asia and Africa. -
INFECTIOUS DISEASES of HAITI Free
INFECTIOUS DISEASES OF HAITI Free. Promotional use only - not for resale. Infectious Diseases of Haiti - 2010 edition Infectious Diseases of Haiti - 2010 edition Copyright © 2010 by GIDEON Informatics, Inc. All rights reserved. Published by GIDEON Informatics, Inc, Los Angeles, California, USA. www.gideononline.com Cover design by GIDEON Informatics, Inc No part of this book may be reproduced or transmitted in any form or by any means without written permission from the publisher. Contact GIDEON Informatics at [email protected]. ISBN-13: 978-1-61755-090-4 ISBN-10: 1-61755-090-6 Visit http://www.gideononline.com/ebooks/ for the up to date list of GIDEON ebooks. DISCLAIMER: Publisher assumes no liability to patients with respect to the actions of physicians, health care facilities and other users, and is not responsible for any injury, death or damage resulting from the use, misuse or interpretation of information obtained through this book. Therapeutic options listed are limited to published studies and reviews. Therapy should not be undertaken without a thorough assessment of the indications, contraindications and side effects of any prospective drug or intervention. Furthermore, the data for the book are largely derived from incidence and prevalence statistics whose accuracy will vary widely for individual diseases and countries. Changes in endemicity, incidence, and drugs of choice may occur. The list of drugs, infectious diseases and even country names will vary with time. © 2010 GIDEON Informatics, Inc. www.gideononline.com All Rights Reserved. Page 2 of 314 Free. Promotional use only - not for resale. Infectious Diseases of Haiti - 2010 edition Introduction: The GIDEON e-book series Infectious Diseases of Haiti is one in a series of GIDEON ebooks which summarize the status of individual infectious diseases, in every country of the world. -
Shigellosis (Bacillary Dysentery) Reporting and Case Investigation
Public Health and Primary Health Care Communicable Disease Control 4th Floor, 300 Carlton St, Winnipeg, MB R3B 3M9 T 204 788-6737 F 204 948-2040 www.manitoba.ca November, 2015 Re: Shigellosis (Bacillary Dysentery) Reporting and Case Investigation Reporting of shigellosis (Shigella species) is as follows: Laboratory: All positive laboratory results for Shigella species are reportable to the Public Health Surveillance Unit by secure fax (204-948-3044). Health Care Professional: Probable (clinical) cases of shigellosis are reportable to the Public Health Surveillance Unit using the Clinical Notification of Reportable Diseases and Conditions form (http://www.gov.mb.ca/health/publichealth/cdc/protocol/form13.pdf ) ONLY if a positive lab result is not anticipated (e.g., poor or no specimen taken, person has recovered). Cooperation in Public Health investigation is appreciated. Regional Public Health or First Nations Inuit Health Branch (FNIHB): Once the case has been referred to Regional Public Health or FNIHB, the Communicable Disease Control Investigation Form (www.gov.mb.ca/health/publichealth/cdc/protocol/form2.pdf) should be completed and returned to the Public Health Surveillance Unit by secure fax (204-948-3044). Sincerely, “Original Signed By” “Original Signed By” Richard Baydack, PhD Carla Ens, PhD Director, Communicable Disease Control Director, Epidemiology & Surveillance Public Health and Primary Health Care Public Health and Primary Health Care Manitoba Health, Healthy Living and Seniors Manitoba Health, Healthy Living and Seniors Communicable Disease Management Protocol Shigellosis (Bacillary Dysentery) Communicable Disease Control Branch 1. Case Definition species cause an acute bacterial disease involving the large and distal small intestine, characterized by 1.1 Confirmed Case diarrhea, fever, nausea, vomiting, abdominal Isolation of Shigella species from an appropriate cramps, tenesmus and sometimes toxemia (1, 4). -
Chart of Foodborne Illness-Causing Organisms in the U.S
Foodborne Illness-Causing Organisms in the U.S. WHAT YOU NEED TO KNOW While the American food supply is among the safest in the world, the Federal government estimates that there are about 48 million cases of foodborne illness annually–the equivalent of sickening 1 in 6 Americans each year. And each year these illnesses result in an estimated 128,000 hospitalizations and 3,000 deaths. The chart below includes foodborne disease-causing organisms that frequently cause illness in the United States. As the chart shows, the threats are numerous and varied, with symptoms ranging from relatively mild discomfort to very serious, life-threatening illness. While the very young, the elderly, and persons with weakened immune systems are at greatest risk of serious consequences from most foodborne illnesses, some of the organisms shown below pose grave threats to all persons. ONSET TIME COMMON NAME ORGANISM AFTER SIGNS & SYMPTOMS DURATION FOOD SOURCES OF ILLNESS INGESTING Bacillus cereus B. cereus food 10-16 hrs Abdominal cramps, watery diarrhea, 24-48 hours Meats, stews, gravies, vanilla poisoning nausea sauce Campylobacter Campylobacteriosis 2-5 days Diarrhea, cramps, fever, and 2-10 days Raw and undercooked poultry, jejuni vomiting; diarrhea may be bloody unpasteurized milk, contaminated water Clostridium Botulism 12-72 hours Vomiting, diarrhea, blurred vision, Variable Improperly canned foods, botulinum double vision, difficulty in swallowing, especially home-canned muscle weakness. Can result in vegetables, fermented fish, respiratory failure -
Infectious Diseases of the Dominican Republic
INFECTIOUS DISEASES OF THE DOMINICAN REPUBLIC Stephen Berger, MD 2018 Edition Infectious Diseases of the Dominican Republic Copyright Infectious Diseases of the Dominican Republic - 2018 edition Stephen Berger, MD Copyright © 2018 by GIDEON Informatics, Inc. All rights reserved. Published by GIDEON Informatics, Inc, Los Angeles, California, USA. www.gideononline.com Cover design by GIDEON Informatics, Inc No part of this book may be reproduced or transmitted in any form or by any means without written permission from the publisher. Contact GIDEON Informatics at [email protected]. ISBN: 978-1-4988-1759-2 Visit www.gideononline.com/ebooks/ for the up to date list of GIDEON ebooks. DISCLAIMER Publisher assumes no liability to patients with respect to the actions of physicians, health care facilities and other users, and is not responsible for any injury, death or damage resulting from the use, misuse or interpretation of information obtained through this book. Therapeutic options listed are limited to published studies and reviews. Therapy should not be undertaken without a thorough assessment of the indications, contraindications and side effects of any prospective drug or intervention. Furthermore, the data for the book are largely derived from incidence and prevalence statistics whose accuracy will vary widely for individual diseases and countries. Changes in endemicity, incidence, and drugs of choice may occur. The list of drugs, infectious diseases and even country names will vary with time. Scope of Content Disease designations may reflect a specific pathogen (ie, Adenovirus infection), generic pathology (Pneumonia - bacterial) or etiologic grouping (Coltiviruses - Old world). Such classification reflects the clinical approach to disease allocation in the Infectious Diseases Module of the GIDEON web application. -
Bacterial and Viral Pathogens of Greatest Concern in Seafood Processing - Public Health Impacts
APPENDIX 7: Bacterial and Viral Pathogens of Greatest Concern in Seafood Processing - Public Health Impacts This guidance represents the Food and Drug Administration’s (FDA’s) current thinking on this topic. It does not create or confer any rights for or on any person and does not operate to bind FDA or the public. You can use an alternative approach if the approach satisfies the requirements of the applicable statutes and regulations. If you want to discuss an alternative approach, contact the FDA staff responsible for implementing this guidance. If you cannot identify the appropriate FDA staff, call the telephone number listed on the title page of this guidance. Bacillus cereus (B. cereus) is the bacterium poisoning. An estimated 249,000 foodborne cases responsible for B. cereus food poisoning. An of perfringens food poisoning occur annually in estimated 27,400 foodborne cases of B. cereus the United States. Symptoms include: abdominal food poisoning occur annually in the United cramps and diarrhea. Symptoms start from 8 States. There are two forms of the intoxication: hours to 1 day after consumption and last for one causes diarrhea, starting from 6 to 15 hours about a day. after consumption, and the other causes vomiting Everyone is susceptible to perfringens food and nausea, starting from 30 minutes to 6 hours poisoning, but it is more common in the young after consumption. Symptoms in both forms last and elderly. about 24 hours. Everyone is susceptible to B. cereus food poisoning While most Escherichia coli (E. coli) are non pathogenic, certain strains of the bacterium are Campylobacter jejuni (C.