AUTHOR’S COPY | AUTORENEXEMPLAR Rev. Neurosci., Vol. 22(5): 565–574, 2011 • Copyright © by Walter de Gruyter • Berlin • Boston. DOI 10.1515/RNS.2011.046 The neurobiology of intertemporal choice: insight from imaging and lesion studies Manuela Sellitto 1,2 , Elisa Ciaramelli 1,2 and me to indulge in the present or postpone the gain ? In taking Giuseppe di Pellegrino 1,2, * into account what they prefer and how long they are willing to wait to obtain it, all intertemporal choices affect people ’ s 1 Dipartimento di Psicologia , Universit à di Bologna, 40127 health, wealth and mood (Frederick et al. , 2002 ). Bologna , Italy Humans and other animals ’ preferences for one option over 2 Centro studi e ricerche in Neuroscienze Cognitive , Polo another refl ect not just the amount of expected reward, but also Scientifi co-Didattico di Cesena, 47521 Cesena , Italy the time at which reward will be received. Economic models * Corresponding author usually explain this in terms of maximization of achieved util- e-mail:
[email protected] ity (Kalenscher and Pennartz , 2008 ). In order to choose the most rewarding course of action, people consider the utility of the temporally proximal outcome against the utility they Abstract assign to a temporally distant outcome. To explore such an issue in the laboratory (both from an economic and psycho- People are frequently faced with intertemporal choices, i.e., logical point of view), these decisional situations are usually choices differing in the timing of their consequences, pre- recreated manipulating the amount of the offered rewards ferring smaller rewards available immediately over larger (e.g., money for humans), and the time at which these rewards rewards delivered after a delay.