pathogens Review Critical Review: Propensity of Premise Plumbing Pipe Materials to Enhance or Diminish Growth of Legionella and Other Opportunistic Pathogens Abraham C. Cullom 1, Rebekah L. Martin 1,2 , Yang Song 1, Krista Williams 3, Amanda Williams 4, Amy Pruden 1 and Marc A. Edwards 1,* 1 Civil and Environmental Engineering, Virginia Tech, 1145 Perry St., 418 Durham Hall, Blacksburg, VA 24061, USA;
[email protected] (A.C.C.);
[email protected] (R.L.M.);
[email protected] (Y.S.);
[email protected] (A.P.) 2 Civil and Environmental Engineering, Virginia Military Institute, Lexington, VA 24450, USA 3 TechLab, 2001 Kraft Drive, Blacksburg, VA 24060, USA;
[email protected] 4 c/o Marc Edwards, Civil and Environmental Engineering, Virginia Tech, 1145 Perry St., 418 Durham Hall, Blacksburg, VA 24061, USA;
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[email protected] Received: 9 October 2020; Accepted: 13 November 2020; Published: 17 November 2020 Abstract: Growth of Legionella pneumophila and other opportunistic pathogens (OPs) in drinking water premise plumbing poses an increasing public health concern. Premise plumbing is constructed of a variety of materials, creating complex environments that vary chemically, microbiologically, spatially, and temporally in a manner likely to influence survival and growth of OPs. Here we systematically review the literature to critically examine the varied effects of common metallic (copper, iron) and plastic (PVC, cross-linked polyethylene (PEX)) pipe materials on factors influencing OP growth in drinking water, including nutrient availability, disinfectant levels, and the composition of the broader microbiome. Plastic pipes can leach organic carbon, but demonstrate a lower disinfectant demand and fewer water chemistry interactions.