Oral Rehabilitation of Young Adult with Amelogenesis Imperfecta 1Vincent WS Leung, 2Bernard Low, 3Yanqi Yang, 4Michael G Botelho
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JCDP Oral Rehabilitation of Young10.5005/jp-journals-10024-2305 Adult with Amelogenesis Imperfecta CASE REPORT Oral Rehabilitation of Young Adult with Amelogenesis Imperfecta 1Vincent WS Leung, 2Bernard Low, 3Yanqi Yang, 4Michael G Botelho ABSTRACT preparation, correcting posterior bilateral cross-bite, as well as an anterior reverse overjet and derotation of the canines. Background: Amelogenesis imperfecta is a heterogeneous group of hereditary disorders that affect the enamel formation Clinical significance: This case report demonstrates the of the primary and permanent dentitions while the remaining effective restoration of AI using a multidisciplinary approach to tooth structure is normal. Appropriate patient care is necessary overcome crowding using a relatively conservative approach. to prevent adverse effects on dental oral health, dental disfigure- Keywords: Amelogenesis imperfecta, Full ceramic crown, ment, and psychological well-being. Orthodontic treatment, Porcelain veneers. Aim: This clinical report presents a 27-year-old Chinese male with How to cite this article: Leung WS, Low B, Yang Y, amelogenesis imperfecta (AI) and his restorative management. Botelho MG. Oral Rehabilitation of Young Adult with Amelogenesis Case report: This clinical report presents a 27-year-old Chinese Imperfecta. J Contemp Dent Pract 2018;19(5):599-604. male with AI and his restorative management. Extraoral exami- Source of support: Nil nation showed a skeletal class III profile and increased lower facial proportion. Intraorally, all the permanent dentition was Conflict of interest: None hypoplastic with noticeable tooth surface loss and a yellow- brown appearance. This was complicated with a mild maloc- BACKGROUND clusion and food packing on his posterior teeth. The patient wanted to improve his appearance and masticatory efficiency. Amelogenesis imperfecta is a heterogeneous group of Orthodontic treatment was performed to treat the mild malocclu- hereditary disorders that affect the enamel formation sion and create physiological interproximal spacing to minimize of the primary and permanent dentitions.1 There is a tooth preparation and facilitate oral hygiene. wide diversity of enamel malformation observed in AI. Conclusion: This report demonstrates how a multidisciplinary Witkop/Sauk classified three major types of AI.2 The approach for the management of AI can achieve a predict- diversity of the condition is believed to reflect the differ- able, functional, and esthetic outcome. Orthodontic treatment ences in the timing during which amelogenesis is affected. facilitated a conservative prosthodontic treatment outcome by selectively increasing interproximal space, minimizing tooth There are three major types of AI classified as: hypoplas- tic, hypocalcified, and hypomaturation. Hypoplastic AI usually appears pitted, thin, and tinged with a yellow- 1Private Practitioner, Shop B, G/F, Millennium Court, 72 Shau brown color and has a hard texture. Radiographically, the Kei Wan Road, Sai Wan Ho, Hong Kong enamel contrasts normally from dentin. Hypocalcified 2Private Practitioner, 318 Glen Osmond Rd, Myrtle Bank, SA 5064 AI enamel shows a normal thickness on eruption, but is 3Department of Orthodontics, Faculty of Dentistry, The University weak in structure, and appears opaque and chalky and of Hong Kong, The Prince Philip Dental Hospital, Sai Ying Pun is easily abraded and detachable from the underlying Hong Kong, China dentin. Radiographically, the enamel is less radiopaque 4 Department of Prosthodontics, Faculty of Dentistry, The than dentin. Hypomaturation AI enamel is slightly softer, University of Hong Kong, The Prince Philip Dental Hospital, Sai Ying Pun, Hong Kong, China but is not hypocalcified. The color is opaque, mottled white, yellow and sometimes brown. Radiographically, Corresponding Author: Michael G Botelho, Department of Prosthodontics, The University of Hong Kong, Room 3B19, The it shares a similar radiodensity as dentin. A variety of Prince Philip Dental Hospital, 34, Hospital Road, Sai Ying Pun nonenamel manifestations may also be present in AI, Hong Kong, China, e-mail: [email protected], e-mail: botelho@ such as delayed eruption, congenitally missing teeth, hku.hk crown resorption, root resorption, pulp calcification, and The Journal of Contemporary Dental Practice, May 2018;19(5):599-604 599 Vincent WS Leung et al gingival hyperplasia. Some other craniofacial features detachable by an explorer. The crown height was short may involve, such as reverse curve of Spee, anterior open in the posterior region. Interproximal caries on teeth #17 bite, or a vertical growth pattern.3 mesial, #16 distal and mesial, #26 distal, and #27 mesial Enamel is derived from epithelial (ectodermal) origin. were detected due to repeated food trapping in these areas. When the enamel is starting to form after the initiation The posterior teeth were in bilateral cross-bite with a of dentinogenesis, cells derived from the internal enamel reversed overjet and the teeth #12 and #13 were in reverse epithelium undergoes three functional stages: presecre- overjet also. Teeth #13 and #23 were rotated distally. There tory, secretory, and maturation.4 The ameloblasts acquire was minimal overjet and overbite of the anterior teeth, their characteristics and develop the apparatus to secrete malalignment and mild crowding. the organic matrix at the presecretory stage. Then they The free-way-space measured was 2 mm. The centric secrete the entire thickness of enamel at the secretory relationship and the centric occlusion were coincided. stage. Finally, the ameloblasts facilitate inorganic ions to No occlusal interference was detected during lateral be secreted and exchanged for water and organic content, excursion (Fig. 1). resulting in a highly organized hydroxyapatie crystal occupying 95% of the matrix volume, thereby producing Radiographic Findings the fully mineralized enamel. A panoramic radiograph showed all of the erupted teeth to have a reduced thickness of enamel but with a normal CASE REPORT dentin and pulpal appearance. Tooth #48 was impacted A 27-year-old Chinese male was referred to the with a normal thickness of enamel, but it was less radi- Prosthodontic Department, Prince Philip Dental Hospital opaque than dentin, and it was difficult to define the at the University of Hong Kong. He requested to improve dentin–enamel junction (Fig. 2). his dental appearance and chewing efficiency. He reported having increasing difficulty to grind the food into small Diagnosis enough pieces for swallowing. He also complained of The patient was diagnosed with a hypoplastic type AI, food trapping in between approximal surface where the generalized gingivitis, and caries on teeth #17M #16D, M enamel had cleaved off which was likely responsible for #26D #27M. A mild malocclusion with teeth #12 #13 in some interproximal dental decay. The appearance and reverse overjet, teeth #13 and #23 mesiobuccally rotated structural integrity of the patient’s dentition were signifi- and a bilateral posterior cross-bite. cantly compromised. The teeth appeared yellow-brown in color and had a rough and soft surface texture with a marked tooth surface loss of the enamel, especially on Treatment Objective the axial surfaces, which resulted in a change of contour The goal for treatment was to control active dental dis- of the teeth including loss of interproximal enamel mar- eases, restore the stomatognathic function in terms of mas- ginal ridges which facilitated food packing. He had no tication and speech, prevention of food packing, improve complaints of dentin hypersensitivity. esthetics, and facilitate self-administered oral hygiene care. According to the patient, his father had experienced similar problems and finally became edentulous and is now Treatment Plan wearing complete dentures. This motivated the patient to seek treatment for his condition. The medical history was Based on the multifactorial nature of this case, a cross- unremarkable and the patient was a nonsmoker. disciplinary approach was required to create space for prosthetic restoration and correct tooth alignment. Extraoral Examination A treatment plan was formulated with a key aim of facilitating the prosthodontic outcome for the recreation of The patient presented with increased lower facial propor- posterior interproximal spacing so as to reduce the amount tion and competent lips. There was no facial asymmetry of interproximal tooth preparation and to create a more or signs or symptoms of temporal mandibular joint physiological contour for better oral hygiene practices. disorders. This was achieved by way of upper arch expansion and proclination of the upper incisors to create posterior inter- Intraoral Examination proximal space. In addition, correction of the posterior, #12 The patient presented with poor oral hygiene, bleeding on and #13 cross-bites, derotation of the teeth #13 and #23, gingival probing, although no probing depth was greater and an increase of the anterior overjet were planned. The than 4 mm. The soft tissues appeared normal and healthy. correction of the malaligned canines would help establish The enamel was yellow-brown, rough, soft, and easily canine guidance. The increase in anterior overjet will also 600 JCDP Oral Rehabilitation of Young Adult with Amelogenesis Imperfecta A B C Figs 1A to C: (A) Preoperative frontal view showing severe AI and teeth 13 and 12 cross-bite. (B) Preoperative upper arch showing rotated teeth 13 and 23, loss of tooth surface substance and morphology. (C)