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Chromosome 21 Leading Edge Gene Set

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Chromosome 21 Leading Edge Gene Set Chromosome 21 Leading Edge Gene Set Genes from chr21q22 that are part of the GSEA leading edge set identifying differences between trisomic and euploid samples. Multiple probe set IDs corresponding to a single gene symbol are combined as part of the GSEA analysis. Gene Symbol Probe Set IDs Gene Title 203865_s_at, 207999_s_at, 209979_at, adenosine deaminase, RNA-specific, B1 ADARB1 234539_at, 234799_at (RED1 homolog rat) UDP-Gal:betaGlcNAc beta 1,3- B3GALT5 206947_at galactosyltransferase, polypeptide 5 BACE2 217867_x_at, 222446_s_at beta-site APP-cleaving enzyme 2 1553227_s_at, 214820_at, 219280_at, 225446_at, 231860_at, 231960_at, bromodomain and WD repeat domain BRWD1 244622_at containing 1 C21orf121 240809_at chromosome 21 open reading frame 121 C21orf130 240068_at chromosome 21 open reading frame 130 C21orf22 1560881_a_at chromosome 21 open reading frame 22 C21orf29 1552570_at, 1555048_at_at, 1555049_at chromosome 21 open reading frame 29 C21orf33 202217_at, 210667_s_at chromosome 21 open reading frame 33 C21orf45 219004_s_at, 228597_at, 229671_s_at chromosome 21 open reading frame 45 C21orf51 1554430_at, 1554432_x_at, 228239_at chromosome 21 open reading frame 51 C21orf56 223360_at chromosome 21 open reading frame 56 C21orf59 218123_at, 244369_at chromosome 21 open reading frame 59 C21orf66 1555125_at, 218515_at, 221158_at chromosome 21 open reading frame 66 C21orf7 221211_s_at chromosome 21 open reading frame 7 C21orf77 220826_at chromosome 21 open reading frame 77 C21orf84 239968_at, 240589_at chromosome 21 open reading frame 84 1552819_at, C21orf86 226995_at,228908_s_at,228909_at chromosome 21 open reading frame 86 C21orf89 1552876_at, 1552877_s_at chromosome 21 open reading frame 89 C21orf9 1554203_at chromosome 21 open reading frame 9 C21orf90 1554953_a_at, 1554954_at chromosome 21 open reading frame 90 CBR1 209213_at carbonyl reductase 1 chromatin assembly factor 1, subunit B CHAF1B 204775_at (p60) CLDN14 210689_at claudin 14 CLIC6 227742_at, 242913_at chloride intracellular channel 6 CRYAA 210199_at crystallin, alpha A 1552347_at, 1554767_s_at, 1560609_at, CRYZL1 219767_s_at, 226151_x_at crystallin, zeta (quinone reductase)-like 1 CSTB 201201_at, 236449_at cystatin B (stefin B) 1552677_a_at,1554967_at,1554969_x_at, 1555301_a_at,1556127_at,1561286_a_at, DIP2 disco-interacting protein 2 homolog A DIP2A 215529_x_at,227199_at (Drosophila) DONSON 221677_s_at downstream neighbor of SON DSCR3 203635_at, 217309_s_at Down syndrome critical region gene 3 DSCR6 207267_s_at Down syndrome critical region gene 6 dual-specificity tyrosine-(Y)-phosphorylation DYRK1A 209033_s_at, 211079_s_at, 211541_s_at regulated kinase 1A phosphoribosylglycinamide formyltransferase, 210005_at,212378_at,212379_at,216990_ phosphoribosylglycinamide synthetase, GART at,217445_s_at,230097_at,244822_at phosphoribosylaminoimidazole synthetase H2BFS 208579_x_at H2B histone family, member S holocarboxylase synthetase (biotin- (proprionyl-Coenzyme A-carboxylase (ATP- HLCS 207833_s_at, 209399_at hydrolysing)) ligase) high-mobility group nucleosome binding HMGN1 200943_at, 200944_s_at domain 1 204191_at, 225661_at, 225669_at, interferon (alpha, beta and omega) receptor IFNAR1 236478_at 1 interferon (alpha, beta and omega) receptor IFNAR2 204785_x_at, 204786_s_at, 201642_at 2 interferon gamma receptor 2 (interferon IFNGR2 201642_at gamma transducer 1) 207322_at, 209297_at, 209298_s_at, ITSN1 210713_at, 35776_at intersectin 1 (SH3 domain protein) potassium voltage-gated channel, Isk- KCNE1 208514_at, 236407_at, 221095_s_at related family, member 1 potassium voltage-gated channel, Isk- KCNE2 221095_s_at related family, member 2 KRTAP10- 12 237853_x_at keratin associated protein 10-12 KRTAP13- 1 1564921_at keratin associated protein 13-1 KRTAP19- 1 1556410_a_at keratin associated protein 19-1 LOC28483 7 1563088_a_at hypothetical protein LOC284837 LRRC3 221017_s_at leucine rich repeat containing 3 MCM3APA minichromosome maintenance complex S 1560542_at, 220459_at, 232740_at component 3 associated protein antisense myxovirus (influenza virus) resistance 2 MX2 204994_at (mouse) NADH dehydrogenase (ubiquinone) NDUFV3 226209_at, 226616_s_at flavoprotein 3, 10kDa OLIG2 213824_at, 213825_at oligodendrocyte lineage transcription factor 2 PCNT 203660_s_at, 233387_s_at pericentrin PCP4 205549_at Purkinje cell protein 4 PDE9A 205593_s_at, 237139_at phosphodiesterase 9A 1566670_at, 202671_s_at, 218018_at, PDXK 218019_s_at, 222492_at, 1566671_a_at pyridoxal (pyridoxine, vitamin B6) kinase PFKL 201102_s_at, 211065_x_at phosphofructokinase, liver phosphatidylinositol glycan anchor PIGP 221689_s_at biosynthesis, class P PLAC4 214750_at, 227519_at, 231454_at placenta-specific 4 1555546_a_at, 207448_at, 207449_s_at, POFUT2 209578_s_at protein O-fucosyltransferase 2 PP9284 /// transmembrane protease, serine 2 /// TMPRSS2 226553_at hypothetical protein LOC100130534 230777_s_at, 231931_at, 234524_at, PRDM15 236061_at PR domain containing 15 202098_s_at, 210384_at, 221564_at, PRMT2 228722_at, 228725_x_at protein arginine methyltransferase 2 PWP2H 209336_at periodic tryptophan protein homolog (yeast) receptor-interacting serine-threonine kinase RIPK4 221215_s_at, 234730_s_at 4 RSPH1 /// TSGA2 230093_at radial spoke head 1 homolog 208129_x_at, 209359_x_at, 209360_s_at, 210365_at, 210805_x_at, 211179_at, 211180_x_at, 211181_x_at, 211182_x_at, runt-related transcription factor 1 (acute RUNX1 211620_x_at, 217263_x_at myeloid leukemia 1; aml1 oncogene) SH3 domain binding glutamic acid-rich SH3BGR 204979_s_at protein SIM2 1557900_at, 206558_at, 208157_at single-minded homolog 2 (Drosophila) 1555952_at, 209775_x_at, 209776_s_at, Solute carrier family 19 (folate transporter), SLC19A1 209777_s_at, 211576_s_at, 229639_s_at member 1 SNF1LK 208078_s_at, 232470_at SNF1-like kinase superoxide dismutase 1, soluble SOD1 200642_at (amyotrophic lateral sclerosis 1 (adult)) 201085_s_at, 201086_x_at, 213538_at, SON 214988_s_at, 226465_s_at SON DNA binding protein TFF2 214476_at trefoil factor 2 (spasmolytic protein 1) TFF3 204623_at trefoil factor 3 (intestinal) 1555446_s_at, 208184_s_at, 209412_at, TMEM1 215269_at transmembrane protein 1 TMEM50B 219600_s_at, 222907_x_at, 225182_at transmembrane protein 50B TMPRSS2 1570433_at, 205102_at, 211689_s_at transmembrane protease, serine 2 transient receptor potential cation channel, TRPM2 205708_s_at subfamily M, member 2 1569472_s_at, 208073_x_at, 208661_s_at, 208662_s_at, 208663_s_at, TTC3 208664_s_at, 210645_s_at tetratricopeptide repeat domain 3 1557053_s_at, 209041_s_at, ubiquitin-conjugating enzyme E2G 2 (UBC7 UBE2G2 209042_s_at, 232755_at homolog, yeast) ZNF295 225539_at, 233952_s_at zinc finger protein 295 .
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