DOCSLIB.ORG

Tesis Aliaga Huashuayo Rosita Melany

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Tesis Aliaga Huashuayo Rosita Melany UNIVERSIDAD PRIVADA AUTÓNOMA DEL SUR FACULTAD CIENCIAS DE LA SALUD ESCUELA PROFESIONAL FARMACIA Y BIOQUÍMICA TESIS PARA OPTAR EL TÍTULO PROFESIONAL DE QUÍMICO FARMACÉUTICO “COMPARACIÓN DEL CONTENIDO DE FENOLES TOTALES Y CAPACIDAD ANTIOXIDANTE DE TRES TIPOS DE EXTRACTOS DE HOJAS DE Larrea divaricata Cav. (JARILLA HEMBRA), AREQUIPA 2021” PRESENTADO POR: BACH. HUASHUAYO CHACONDORI ELMA YELY BACH. ALIAGA HUASHUAYO ROSITA MELANY ASESOR: MSc. Elvis Gilmar Gonzales Condori AREQUIPA - PERÚ 2021 UNIVERSIDAD PRIVADA AUTÓNOMA DEL SUR FACULTAD CIENCIAS DE LA SALUD ESCUELA PROFESIONAL FARMACIA Y BIOQUÍMICA TESIS “COMPARACIÓN DEL CONTENIDO DE FENOLES TOTALES Y CAPACIDAD ANTIOXIDANTE DE TRES TIPOS DE EXTRACTOS DE HOJAS DE Larrea divaricata Cav. (JARILLA HEMBRA), AREQUIPA 2021” PRESENTADO POR: BACH. HUASHUAYO CHACONDORI ELMA YELY BACH. ALIAGA HUASHUAYO ROSITA MELANY PARA OPTAR EL TÍTULO PROFESIONAL DE QUÍMICO FARMACÉUTICO APROBADO POR: PRESIDENTE DEL JURADO: MG. CARMEN BEATRIZ BURGOS MACEDO SECRETARIO DEL JURADO: MG. BETTY MARILIA SALAZAR PINTO VOCAL DEL JURADO: MG. ING. ANTONIETA SALOME CALIZAYA CHIRI DEDICATORIA A Dios, porque ha estado siempre conmigo cuidándome y dándome fortaleza para continuar, del mismo modo a mis padres, por haberme impulsado a ser la persona que soy ahora; gracias a ellos por la motivación y la fortaleza que me brindaron para alcanzar todos mis anhelos, sobre todo porque depositaron su entera confianza en mi persona. A mi esposo Milton, por acompañarme y apoyarme en este difícil camino que he transitado con esmero y sacrificio, a ti mi amor, por tu paciencia y apoyo incondicional impulsándome siempre seguir adelante y no desfallecer. A mis hijitos hermosos, que son mi motor y mayor motivación para nunca rendirme y seguir siempre para adelante y de esta manera ser un ejemplo para ellos. A mis hermanos y sobrinos hermosos, por estar siempre presentes, acompañándome a lo largo de mi carrera brindándome sus consejos y palabras de aliento sobre todo por ese apoyo incondicional que me dieron ¡Gracias a todos los Amo! ELMA YELY HUASHUAYO CHACONDORI i DEDICATORIA A Dios, por darme vida y Salud, acompañarme y fortalecerme todos los días de mi vida, por permitirme el haber llegado hasta este momento tan importante para mí. ¡Gracias Señor! por este logro de obtener el título profesional de Químico Farmacéutico, que me permitirá servir a los demás. Esta tesis está dedicada con muchísimo amor y orgullo a mis padres, que me enseñaron a ser libre e independiente. A mis hermanos, sobrinos llenos de amor y alegría, que son la mayor bendición de mi vida quienes siempre estuvieron apoyándome en todo momento con sus valores, palabras de aliento para no desfallecer y sobre todo confiar en mí. Gracias a las personas que con un gesto, una sonrisa, una mirada y una palabra me incentivó para seguir adelante. ¡Gracias a ustedes ¡ A mis docentes por formarme profesionalmente, por brindarme sus enseñanzas, conocimientos y por su compresión en situaciones complicadas ya que trabajar y estudiar no es nada fácil pero no imposible. Por último dedico a mi compañera y amiga Gladis Bolaños que ahora desde el cielo me cuida, excelente madre e hija, un gran modelo de persona, que por más obstáculos que se le presentaba en la vida jamás se rendía, porque siempre estuvo ahí cuando más la necesite, por sus consejos y regaños. ROSITA MELANY ALIAGA HUASHUAYO i AGRADECIMIENTO Primeramente nuestro infinito agradecimiento a Nuestro Padre Celestial, por guiar nuestro camino e iluminar nuestra mente, por darnos la suficiente fortaleza, valentía para seguir siempre adelante y así poder culminar el presente trabajo. A nuestro asesor, MSc. Elvis Gilmar Gonzales Condori quien acepto ser nuestro asesor en la realización de nuestra tesis, quien nos brindó apoyo, paciencia, tiempo y sabiduría, para poder realizar y culminar nuestra tesis. Nuestro agradecimiento a nuestra casa de estudios, que nos acogió en sus prestigiosas aulas estudiantiles, de la misma manera nuestro agradecimiento es a los docentes, quienes compartieron sus enseñanzas, conocimientos y sabidurías con nosotros a lo largo de la formación de nuestra carrera profesional. También nuestro agradecimiento a los Miembros del Jurado Calificador por el valioso tiempo prestado para de esta manera poder exponerles nuestro presente trabajo de investigación. Finalmente a todos nuestros familiares y amigos cercanos, que estuvieron constantemente apoyándonos. ELMA Y ROSITA ii RESUMEN En la actualidad existen diversos métodos para la elaboración de extractos vegetales, asimismo, una diversidad de solventes extractores y cada uno de ellos extrae diversas proporciones de determinados metabolitos que es debido a su afinidad por el solvente a utilizar, por esta razón, en la presente tesis se buscó comparar el contenido de fenoles totales y capacidad antioxidante de tres tipos de extractos de hojas de Larrea divaricata Cav.(Jarilla hembra) usando tres solventes diferentes (Metanol, Etanol y solución hidroalcohólica), dando como resultado que, el contenido de fenoles totales en los extractos metanólicos, hidroalcohólicos y etanólicos de hojas de Larrea divaricata Cav.(Jarilla hembra) son de 866.50, 882.13 y 846.97 mg EAG/ 100mL respectivamente, presentando diferencia significativa (p<0.05). Con relación a la capacidad antioxidante que fue determinada por el método de DPPH se encontró valores de 425.91, 480.45 y 448.64 mg ET/mL para los extractos metanólicos, hidroalcohólicos y etanólicos respectivamente, encontrando diferencia significativa (p<0.05). En conclusión, si existe evidencia científica para decir que los solventes extractores influyen el contenido de fenoles totales y capacidad antioxidante en los tres tipos de extractos de hojas de Larrea divaricata Cav. (Jarilla hembra). Palabras clave. Jarilla hembra, extracto metanólico, extracto hidroalcohólico; extracto etanólico, Capacidad antioxidante; Fenoles totales. iii ABSTRACT Nowadays there are several methods for the elaboration of vegetable extracts, also, a diversity of extracting solvents and each one of them extracts different proportions of certain metabolites due to their affinity for the solvent to be used, reason why, In the present thesis, the total phenol content and antioxidant capacity of three extracts of leaves of Larrea divaricata Cav. (Jarilla female) were compared using three different solvents (Methanol, Ethanol and hydroalcoholic solution), giving as a result that, the concentration of total phenols in the methanolic, hydroalcoholic and ethanolic extracts of leaves of Larrea divaricata Cav. (Jarilla female) are 866. 50, 882.13 and 846.97 mg GSD/ 100mL respectively, presented significant difference (p<0.05). In relation to antioxidant capacity determined by DPPH method, values of 425.91, 480.45 and 448.64 mg ET/mL were found for methanolic, hydroalcoholic and ethanolic extracts respectively, finding significant difference (p<0.05). In conclusion, there is scientific evidence to say that extracting solvents influence total phenol content and antioxidant capacity of methanolic, ethanolic and hydroalcoholic extracts from Larrea divaricata Cav (Jarilla female) leaves. Keywords. Female Jarilla, methanolic extract, hydroalcoholic extract; ethanolic extract, antioxidant capacity; total phenols. iv ÍNDICE DE CONTENIDO DEDICATORIA ....................................................................................................... i DEDICATORIA ....................................................................................................... i AGRADECIMIENTO .............................................................................................. ii RESUMEN ........................................................................................................... iii ABSTRACT ........................................................................................................... iv ÍNDICE DE TABLAS ........................................................................................... viii ÍNDICE DE FIGURAS ........................................................................................... ix ÍNDICE DE APÉNDICES ....................................................................................... x LISTA DE ABREBIATURAS .................................................................................. xi INTRODUCCIÓN ................................................................................................. xii CAPÍTULO I ........................................................................................................... 1 EL PROBLEMA DE INVESTIGACIÓN ................................................................... 1 1.1. Descripción de la realidad problemática ................................................. 1 1.2. Formulación del problema...................................................................... 2 1.2.1. Problema General .............................................................................. 2 1.2.2. Problemas Secundarios ...................................................................... 2 1.3. Objetivos ................................................................................................ 2 1.3.1. Objetivo General ................................................................................. 2 1.3.2. Objetivos Específicos ......................................................................... 3 1.4. Justificación ........................................................................................... 3 2.1. Antecedentes de Investigación .............................................................
Load more

Recommended publications
  • Potential Use of Low-NDGA Larrea Divaricata Extracts As Antioxidant in Foods
    Rev. peru. biol. 18(2): 159 - 164 (Agosto 2011) © Facultad de Ciencias Biológicas UNMSM Aqueous extract of LARREA DIVARICATA leaves as antioxidantISSN 1561-0837 in foods Potential use of low-NDGA Larrea divaricata extracts as antioxidant in foods Uso potencial de extractos de Larrea divaricata con bajo contenido de NDGA como antioxidantes en comidas Sebastian Turner1, Roberto Davicino1, Rosario Alonso1, Graciela Ferraro1, 2, Rosana Filip1, 2 and Claudia Anesini1, 2 1 Institute of Chemical and Me- tabolism of Drugs- University of Abstract Buenos Aires- National Council of Scientific and Technical Research ( Larrea divaricata Cav. is widely distributed in Argentina. Aqueous extract, of its leaves, has documented IQUIMEFA-UBA-CONICET), Junín antitumoral and immunomodulatory activities. In this study, the antioxidant activity of aqueous extract and a 956, University of Buenos Aires, Buenos Aires, Argentina. component, nordihydroguaiaretic acid was determined and compared using different assays. Both the aqueous 2 Pharmacognosy Unit, Faculty extract and nordihydroguaiaretic acid exhibited antioxidant activity. However, results show that it is very likely of Pharmacy and Biochemistry, that compounds other than nordihydroguaiaretic acid could be involved in the antioxidant activity of the extract. University of Buenos Aires, Junín Since nordihydroguaiaretic acid is nephrotoxic and hepatotoxic agent, it is important to direct efforts toward the 956, Buenos Aires, Argentina. potential use of low-nordihydroguaiaretic acid L. divaricata extracts as antioxidant in foods. Correspondence to: Dr. Roberto Davicino, Immunology Keywords: Nordihydroguaiaretic acid; Larrea divaricata; antioxidant activity; superoxide dismutase; catalase Unit, National University of San Luis, Ejercito de los Andes 950, San Luis-Argentina. Resumen Email Roberto Davicino: Larrea divaricata Cav.
    [Show full text]
  • Redalyc.Evaluation of Resin Content and the Antifungal Effect of Larrea
    Revista Mexicana de Fitopatología ISSN: 0185-3309 [email protected] Sociedad Mexicana de Fitopatología, A.C. México Lira Saldívar, Ricardo Hugo; Balvantín García, Gloria Franciela; Hernández Castillo, Francisco Daniel; Gamboa Alvarado, Roberto; Jasso de Rodríguez, Diana; Jiménez Díaz, Florencio Evaluation of Resin Content and the Antifungal Effect of Larrea tridentata (Sesse and Moc. Ex D.C.) Coville Extracts from Two Mexican Deserts Against Pythium sp. Pringsh Revista Mexicana de Fitopatología, vol. 21, núm. 2, julio-diciembre, 2003, pp. 97-101 Sociedad Mexicana de Fitopatología, A.C. Texcoco, México Available in: http://www.redalyc.org/articulo.oa?id=61221201 How to cite Complete issue Scientific Information System More information about this article Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Journal's homepage in redalyc.org Non-profit academic project, developed under the open access initiative Revista Mexicana de FITOPATOLOGIA/ 97 Evaluation of Resin Content and the Antifungal Effect of Larrea tridentata (Sesse and Moc. Ex D.C.) Coville Extracts From two Mexican Deserts Against Pythium sp. Pringsh. Ricardo Hugo Lira-Saldívar, Centro de Investigación en Química Aplicada, Blvd. Enrique Reyna Hermosillo 140, Saltillo, Coahuila, México CP 25100; Gloria Franciela Balvantín- García, Facultad de Ciencias Químicas, Universidad Autónoma de Coahuila, Blvd. Venustiano Carranza y Francisco Cárdenas Valdés, Saltillo, Coahuila CP 25100; Francisco Daniel Hernández-Castillo, Roberto Gamboa-Alvarado,
    [Show full text]
  • Newlander Thesis FINAL
    ABSTRACT In many Mojave Desert ecosystems, water infiltrates to root-zones in greatest proportion via washes. As such, washes have a pronounced effect on plant dispersion and size across these landscapes. Desert roads alter the natural spatial patterns of washes on alluvial fans (locally called bajadas) and potentially affect plant production and distribution. As a winter-rainfall dominated ecosystem, climate changes in the Mojave Desert that increase summer precipitation may also play an important role in altering vegetation processes influenced by washes. Road effects on the spatial distribution of desert plants on a Mojave Desert bajada were examined using remotely sensed LiDAR data and ground based measurements of plant size. Plant physiological responses to summer wash flow were also quantified by measuring gas exchange and water status of two dominant perennial species, Larrea tridentata and Ambrosia dumosa. Larrea and Ambrosia plants were nearly 7x and 4x larger where wash flow has been enhanced by road culverts, relative to undisturbed areas and areas where flow has been cut-off by the presence of a road/railroad. Clustering of large plants occurred along wash margins, with clustering most pronounced in areas of enhanced wash flow. No clustering was found where wash flow has been eliminated. For ecophysiological traits, both species showed pronounced responses to the pulse of water; however, these responses varied as a function of distance from wash. Larrea plants within 3 m and Ambrosia plants within ca. 2 m from the wash responded to the pulse of water. Leaf phenology dictated the timing ii of carbon gain as Larrea experienced a rapid but short-lived increase in stomatal conductance compared to a significant response for over a month following the pulse for Ambrosia.
    [Show full text]
  • Biophysical Evaluation of Fertility Islands in the Arid Chaco (Argentina) Karlin, M
    AGRISCIENTIA, 2021, VOL. 38: 1-13 Biophysical evaluation of fertility islands in the Arid Chaco (Argentina) Karlin, M. S., Coirini, R. O., Ringuelet, A, Bernasconi Salazar, J. R., Cora, A., Contreras, A. M., Bravo, M.B. and Buffa, E. V. DOI: 10.31047/1668.298x.v38.n1.30529 SUMMARY Forests degradation in arid and semi-arid lands may conduct to the formation of “fertility islands” due to the accumulation of soil particles, water, nutrients and biomass under trees and shrubs. In the Arid Chaco fertility islands are characterised by the presence of Prosopis flexuosa and Larrea divaricata. The objective was to evaluate biophysical variables in soil, microclimate and the plant response under canopy and in intercanopy. Infiltrability, microtopography, soil bulk density, soil and air moisture and temperature, and light were measured under the canopy, at the limit of the canopy and in the intercanopy. These variables were correlated with the litter and plant frequencies associated with the fertility islands. P. flexuosa canopy and litter understorey tend to maintain more soil moisture compared with the intercanopy, by reducing soil and air temperature and by increasing air moisture. This increases the frequency of Dyksterhuis’ decreaser species. Under L. divaricata the canopy effect is not as effective as that of P. flexuosa and understorey plant response is not significative. Key words: forage; Larrea; microclimate; physical fertility; Prosopis; soil moisture. Karlin, M. S., Coirini, R. O., Ringuelet, A, Bernasconi Salazar, J. R., Cora, A., Contreras, A. M., Bravo, M. B. y Buffa, E. V. 2021. Evaluación biofísica de islas de fertilidad en el Chaco Árido (Argentina).
    [Show full text]
  • Larrea Divaricata Cav. Aqueous Extract and Nordihydroguariaretic Acid Modulate Oxidative Stress in Submandibular Glands of Diabe
    Peralta et al. BMC Complementary and Alternative Medicine (2019) 19:227 https://doi.org/10.1186/s12906-019-2636-z RESEARCH ARTICLE Open Access Larrea divaricata Cav. aqueous extract and nordihydroguariaretic acid modulate oxidative stress in submandibular glands of diabetic rats: a buccal protective in diabetes Ignacio Peralta1,3, Carla Marrassini1,3, María Laura Barreiro Arcos2, Graciela Cremaschi2, María Rosario Alonso1 and Claudia Anesini1,3* Abstract Background: Oxidative stress is an imbalance between the levels of reactive oxygen species (ROS), reactive nitrogen species (RNS) and endogenous antioxidants. The aetiology and pathogenesis of several oral diseases are attributed to this process. The antioxidant enzymes secreted in the saliva by submandibular glands maintain oral health through the scavenging of ROS. The objective of this work was to study the capacity of an aqueous extract of L. divaricata (AE), and its majority compound, nordihydroguariaretic acid (NDGA), to modulate the pro-oxidant/ antioxidant status in submandibular glands in a model of oxidative stress induced by streptozotocin (STZ) in rats. Methods: To induce oxidative stress with STZ, a group of animals was treated i.p. with 1 X PBS (control group) and other group was injected i.p. once with STZ (60 mg/kg). Ten days after the treatment, blood samples were taken from the tail vain to determine the glucose levels. Animals with glucose values ≥300 mg/ml were selected. The submandibular glands of control and STZ treated animals were incubated with either the AE (500 μg/ml) or with NDGA (1.5 μg/ml), and the content of malondialdehyde (MDA), protein carbonyl groups, ROS and RNS, and the activity and expression of peroxidase (Px), superoxide dismutase (SOD) and inducible nitric oxide synthase (iNOS) were assayed.
    [Show full text]
  • The Monte and Chaco Regions of ARGENTINA the Boyce Thompson Arboretum and Desert Legume Program Expedition
    The Monte and Chaco Regions of ARGENTINA The Boyce Thompson Arboretum and Desert Legume Program Expedition by Matthew B. Johnson Figure 1. Tephrocactus aoracanthus, northwest of San Juan. MJB Johnson Argentina 29 picked up a rental vehicle and drove to our hotel in the city. Matthew B. Johnson Driving in Argentina, particularly in urban areas, is not for the Desert Legume Program timid. Boyce Thompson Arboretum and We visited a small nature preserve in the hills on the west side the University of Arizona of Mendoza for our first look at the plants of this region of 2120 East Allen Rd. the country. The vegetation in this part of the Monte Desert Tucson, AZ 85719 resembles the vegetation in parts of the Chihuahuan Desert of North America. Shrubs predominate, with a variety of herba- ceous plants and smaller cacti. Many spring-flowering species Editor’s Note: This is an updated version of an article that previously were in bloom. Larrea cuneifolia, one of the South American appeared in Aridus, the Bulletin of The Desert Legume Program of Boyce creosote bushes in the Zygophyllaceae was particularly abun- Thompson Arboretum and The University of Arizona, Issue 13:1, February dant. It is called “jarilla norte sur” after the north south orienta- 2001. tion of the foliage. Also in abundance was Zuccagnia punctata, “jarilla melosa”, a caesalpinioid legume that superficially resembles Larrea from a Argentina is a country of great natural beauty and distance. This attractive evergreen shrub has racemes of small diversity. Extending from north of the Tropic of Capricorn yellow flowers and resinous foliage with an aroma similar to to Tierra del Fuego, much of the country has a dry climate.
    [Show full text]
  • Redalyc.Effect of Prosopis Flexuosa on Understory Species and Its
    Revista de la Facultad de Ciencias Agrarias ISSN: 0370-4661 [email protected] Universidad Nacional de Cuyo Argentina Cesca, Erica M.; Villagra, Pablo E.; Passera, Carlos; Alvarez, Juan A. Effect of Prosopis flexuosa on understory species and its importance to pastoral management in woodlands of the Central Monte Desert Revista de la Facultad de Ciencias Agrarias, vol. 44, núm. 2, 2012, pp. 207-219 Universidad Nacional de Cuyo Mendoza, Argentina Available in: http://www.redalyc.org/articulo.oa?id=382837651010 How to cite Complete issue Scientific Information System More information about this article Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Journal's homepage in redalyc.org Non-profit academic project, developed under the open access initiative ProsopisRev. FCA flexuosa UNCUYO. effects 2012. on 44(2): understory 207-219. species ISSN in impreso the Monte 0370-4661. ISSN (en línea) 1853-8665. Effect of Prosopis flexuosa on understory species and its importance to pastoral management in woodlands of the Central Monte Desert * Efecto de Prosopis flexuosa sobre las especies del sotobosque y su importancia para el manejo pastoril de los algarrobales del desierto del Monte Central Erica M. Cesca 1 Carlos Passera 2, 3 Pablo E. Villagra 1, 3 Juan A. Alvarez 1 Originales: Recepción: 28/10/2011 - Aceptación: 09/10/2012 ABSTRACT RESUMEN In the Monte Biogeographic Province, located En la Provincia Biogeográfica del Monte, in the arid region of Argentina, the presence ubicada en la zona árida de Argentina, la presencia of Prosopis flexuosa DC. produces spatial de Prosopis flexuosaDC. genera heterogeneidad heterogeneity through edaphic modifications and espacial a través de modificaciones edáficas y microclimate changes.
    [Show full text]
  • Antioxidant and Antimicrobial Activities of Larrea Divaricata Cav
    Food and Nutrition Sciences, 2011, 2, 35-46 35 doi:10.4236/fns.2011.21005 Published Online january 2011 (http://www.SciRP.org/journal/fns) Antioxidant and Antimicrobial Activities of Larrea Divaricata Cav. Aqueous Extract on Vitamin C from Natural Orange Juice Patricia Micucci1, Maria Rosario Alonso1, Sebastian Turner1, Roberto Davicino1, Claudia Anesini1,2 1IQUIMEFA-CONICET-UBA, Buenos Aires, Argentina; 2Pharmacognosy Unit, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina Email: [email protected] Received August 10th, 2010; revised October 9th, 2010; accepted October 17th, 2010 ABSTRACT Larrea divaricata Cav. is a South American plant widely distributed in Argentina with reported antioxidant and antim- icrobial activities. Vitamin C (Vit C) the most important water-soluble antioxidant, is degraded upon factors such as oxygen, heat, light, storage time and temperature, during cooking and in presence of microorganisms. The aim of this work was: to study the antioxidant and antimicrobial activity of an aqueous extract of L. divaricata (E) on Vit C pre- pared in water and on Vit C from natural orange juice, submitted to different store conditions such as temperatures and oxygen. The antioxidant activity was determined by DPPH method and used to obtained the relative Vit C concentra- tion; Vit C decreased its activity and concentration under temperature and air oxygen, but E allowed Vit C to recover its antioxidant activity and prevented Vit C microorganism contamination. These studies were performed in view to es- tablish whether L. divaricata can be used as a supplement on orange juices capable to prevent Vit C decay and micro- bial growth.
    [Show full text]
  • Systematics and Evolution of the Genus Deuterocohnia Mez (Bromeliaceae)
    Systematics and evolution of the genus Deuterocohnia Mez (Bromeliaceae) Dissertation zur Erlangung des akademischen Grades eines Doktors der Naturwissenschaften (Dr. rer. nat.) Vorgelegt im Fachbereich Naturwissenschaften der Universität Kassel von Dipl.-Biol. Nicole Schütz Kassel, 2011 Vom Fachbereich Naturwissenschaften der Universität Kassel als Dissertation angenommen. Dekan: Prof. Dr. Friedrich W. Herberg Gutachter: Prof. Dr. Kurt Weising und Prof. Dr. Georg Zizka Prüfungskommission: Prof. Dr. Pierre Ibisch, Prof. Dr. Rüdiger Wagner, Prof. Dr. Kurt Weising, Prof. Dr. Georg Zizka Datum der Disputation: 21.02. 2012 Content I Content 1 INTRODUCTION .....................................................................................................1 1.1 Biology and systematics of the Bromeliaceae Juss......................................................1 1.2 The genus Deuterocohnia Mez................................................................................... 5 1.3 Scope of the present study .......................................................................................... 9 2 MATERIAL AND METHODS................................................................................. 11 2.1 Sources of plant material............................................................................................ 11 2.1.1 Living plant material ....................................................................................................... 11 2.1.2 Herbarium specimens....................................................................................................
    [Show full text]
  • Helicobacter Pylori: a Review Bruna Vidal Bonifácio1, Matheus Aparecido Dos Santos Ramos1, Patricia Bento Da Silva2 and Taís Maria Bauab1*
    Bonifácio et al. Annals of Clinical Microbiology and Antimicrobials 2014, 13:54 http://www.ann-clinmicrob.com/content/13/1/54 REVIEW Open Access Antimicrobial activity of natural products against Helicobacter pylori: a review Bruna Vidal Bonifácio1, Matheus Aparecido dos Santos Ramos1, Patricia Bento da Silva2 and Taís Maria Bauab1* Abstract Throughout the genetic and physiological evolution of microorganisms, the microbiological sciences have been expanding the introduction of new therapeutic trials against microbial diseases. Special attention has been paid to the bacterium Helicobacter pylori, which induces gastric infections capable of causing damage, ranging from acute and chronic gastritis to the development of gastric cancer and death. The use of compounds with natural origins has gained popularity in scientific research focused on drug innovation against H. pylori because of their broad flexibility and low toxicity. The aim of this study was to describe the use of natural products against H. pylori in order to clarify important parameters for related fields. The study demonstrated the vast therapeutic possibilities for compounds originating from natural sources and revealed the need for innovations from future investigations to expand the therapeutic arsenal in the fight against H. pylori infection. Keywords: Helicobacter pylori, Natural products, Antimicrobial activity Additional non-English language - Portuguese No decorrer da evolução genética e fisiológica dos micro-organismos, as ciências microbiológicas encontram-se em expansão, preocupando-se em introduzir novas triagens terapêuticas frente às afecções microbianas, com especial atenção àquelas adquiridas pela bactéria Helicobacter pylori, sendo esta frequentemente envolvida nas infecções gástricas capazes de causar dano ao organismo humano que vão desde gastrites agudas e crônicas ao desenvolvimento de neoplasias gástricas, levando o paciente ao óbito na maioria das vezes.
    [Show full text]
  • Universo Tucumano 39
    Universo Tucumano Nº 39 – Octubre 2019 Universo Tucumano N° 39 Octubre / 2019 ISSN 2618-3161 Los estudios de la naturaleza tucumana, desde las características geológicas del territorio, los atributos de los diferentes ambien- tes hasta las historias de vida de las criaturas que la habitan, son parte cotidiana del trabajo de los investigadores de nuestras Instituciones. Los datos sobre estos temas están disponibles en textos técnicos, específicos, pero las personas no especializadas no pueden acceder fácilmente a los mismos, ya que se encuentran dispersos en muchas publicaciones y allí se utiliza un lenguaje muy técnico. Por ello, esta serie pretende hacer disponible la información sobre diferentes aspectos de la naturaleza de la provincia de Tucumán, en forma científicamente correcta y al mismo tiempo amena y adecuada para el público en general y particularmente para los maestros, profesores y alumnos de todo nivel educativo. La información se presenta en forma de fichas dedicadas a espe- cies particulares o a grupos de ellas y también a temas teóricos generales o áreas y ambientes de la Provincia. Los usuarios pue- den obtener la ficha del tema que les interese o formar con todas ellas una carpeta para consulta. Fundación Miguel Lillo CONICET – Unidad Ejecutora Lillo Miguel Lillo 251, (4000) San Miguel de Tucumán, Argentina www.lillo.org.ar Dirección editorial: Gustavo J. Scrocchi – Fundación Miguel Lillo y Unidad Ejecutora Lillo Claudia Szumik – Unidad Ejecutora Lillo (CONICET – Fundación Miguel Lillo) Diseño y edición gráfica: Gustavo Sanchez – Fundación Miguel Lillo Editor web: Andrés Ortiz – Fundación Miguel Lillo Imágenes de tapa: Larrea cuneifolia (izquierda), fotografía: R.
    [Show full text]
  • Morphoanatomical and Histochemical Characterization of Larrea
    Revista Brasileira de Farmacognosia 28 (2018) 393–401 ww w.elsevier.com/locate/bjp Original article Morphoanatomical and histochemical characterization of Larrea species from Northwestern of Argentina a b a b María Inés Mercado , María Alejandra Moreno , Ana Inés Ruiz , Ivana Fabiola Rodríguez , b b,1 a,∗,1 Iris Catiana Zampini , María Inés Isla , Graciela Inés Ponessa a Instituto de Morfología Vegetal, Área Botánica, Fundación Miguel Lillo, San Miguel de Tucumán, Tucumán, Argentina b Laboratorio de Investigación de Productos Naturales, Instituto de Bioprospección y Fisiología Vegetal, Facultad de Ciencias Naturales e Instituto Miguel Lillo, Universidad Nacional de Tucumán, San Miguel de Tucumán, Tucumán, Argentina a b s t r a c t a r t i c l e i n f o Article history: Larrea divaricata Cav., L. cuneifolia Cav. and L. nitida Cav., Zygophyllaceae, are evergreen xerophytic shrubs Received 10 March 2018 occurring in Northwestern Argentina used in traditional medicine. The aim of this work was to character- Accepted 30 May 2018 ize the morphology, anatomy and histochemistry of the vegetative organs of three Larrea species by light Available online 23 June 2018 and scanning electron microscopy in order to provide supporting data for their correct identification and to determine the site of synthesis and accumulation of its main active compounds. The shape, number Keywords: and percentage of coalescence of leaflets, presence or absence of mucrones and rachis and the shape of Larrea the stipules represented the main botanical differences between the studied Larrea species. Anatomically Morphology three species presented amphystomatic leaves, with thick resinous slightly striated cuticle with resinous Anatomy Histochemistry deposits, polygonal epidermal cells with straight anticlinal walls, ciclocytic, brachy-paracytic and para- Leaf cytic stomatal types, non-glandular trichomes and isolateral mesophyll.
    [Show full text]