Étude Comparative De Deux Protocoles D'anesthésie Par Voie Intramusculaire Lors De

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Étude Comparative De Deux Protocoles D'anesthésie Par Voie Intramusculaire Lors De ÉCOLE NATIONALE VÉTÉRINAIRE D’ALFORT Année 2015 ÉTUDE COMPARATIVE DE DEUX PROTOCOLES D'ANESTHÉSIE PAR VOIE INTRAMUSCULAIRE LORS DE L'OVARIECTOMIE CHEZ LA CHATTE THÈSE Pour le DOCTORAT VÉTÉRINAIRE Présentée et soutenue publiquement devant LA FACULTÉ DE MÉDECINE DE CRÉTEIL Le 22 octobre 2015 par Thomas, Raphaël, Benjamin DRESCO Né le 21 décembre 1990 à Paris 14ème JURY Président : Pr. Professeur à la Faculté de Médecine de CRÉTEIL Membres Directeur : Dr. ZILBERSTEIN Luca, Maître de conférences à l’École Nationale Vétérinaire d’Alfort Assesseur : Pr. TISSIER Renaud, Professeur à l’École Nationale Vétérinaire d’Alfort LISTE DU CORPS ENSEIGNANT Mai 2015 LISTE DES MEMBRES DU CORPS ENSEIGNANT Directeur : M. le Professeur GOGNY Marc Directeurs honoraires : MM. les Professeurs : COTARD Jean-Pierre, MIALOT Jean-Paul, MORAILLON Robert, PARODI André-Laurent, PILET Charles, TOMA Bernard. Professeurs honoraires : Mme et MM. : BENET Jean-Jacques, BRUGERE Henri, BRUGERE-PICOUX Jeanne, BUSSIERAS Jean, CERF Olivier, CHERMETTE René, CLERC Bernard, CRESPEAU François, M. COURREAU Jean-François, DEPUTTE Bertrand, MOUTHON Gilbert, MILHAUD Guy, POUCHELON Jean-Louis, ROZIER Jacques. DEPARTEMENT D’ELEVAGE ET DE PATHOLOGIE DES EQUIDES ET DES CARNIVORES (DEPEC) Chef du département : M. GRANDJEAN Dominique, Professeur - Adjoint : M. BLOT Stéphane, Professeur UNITE DE CARDIOLOGIE DISCIPLINE : NUTRITION-ALIMENTATION - Mme CHETBOUL Valérie, Professeur * - M. PARAGON Bernard, Professeur - Mme GKOUNI Vassiliki, Praticien hospitalier DISCIPLINE : OPHTALMOLOGIE - Mme SECHI-TREHIOU Emilie, Praticien hospitalier - Mme CHAHORY Sabine, Maître de conférences UNITE DE CLINIQUE EQUINE - M. AUDIGIE Fabrice, Professeur UNITE DE PARASITOLOGIE ET MALADIES PARASITAIRES - Mme BERTONI Lélia, Maître de conférences contractuel - M. BLAGA Radu Gheorghe, Maître de conférences (rattaché au DPASP) - Mme BOURZAC Céline, Maître de conférences contractuel - Mme COCHET-FAIVRE Noëlle, Praticien hospitalier - M. DENOIX Jean-Marie, Professeur - M. GUILLOT Jacques, Professeur * - Mme GIRAUDET Aude, Praticien hospitalier * - Mme MARIGNAC Geneviève, Maître de conférences - Mme MESPOULHES-RIVIERE Céline, Praticien hospitalier - M. POLACK Bruno, Maître de conférences - Mme TRACHSEL Dagmar, Praticien hospitalier - Mme RISCO CASTILLO Véronica, Maître de conférences (rattachée au DSBP) UNITE D’IMAGERIE MEDICALE UNITE DE PATHOLOGIE CHIRURGICALE - Mme PEY Pascaline, Maître de conférences contractuel - M. FAYOLLE Pascal, Professeur - Mme STAMBOULI Fouzia, Praticien hospitalier - M. MAILHAC Jean-Marie, Maître de conférences - M. MANASSERO Mathieu, Maître de conférences UNITE DE MEDECINE - M. MOISSONNIER Pierre, Professeur - M. AGUILAR Pablo, Praticien hospitalier - Mme VIATEAU-DUVAL Véronique, Professeur * - Mme BENCHEKROUN Ghita, Maître de conférences - M. ZILBERSTEIN Luca, Maître de conférences - M. BLOT Stéphane, Professeur* - M. CAMPOS Miguel, Maître de conférences associé DISCIPLINE : URGENCE SOINS INTENSIFS - Mme FREICHE-LEGROS Valérie, Praticien hospitalier - Mme STEBLAJ Barbara, Praticien Hospitalier - Mme MAUREY-GUENEC Christelle, Maître de conférences DISCIPLINE : NOUVEAUX ANIMAUX DE COMPAGNIE UNITE DE MEDECINE DE L’ELEVAGE ET DU SPORT - M. PIGNON Charly, Praticien hospitalier - Mme CLERO Delphine, Maître de conférences contractuel - M. FONTBONNE Alain, Maître de conférences - M. GRANDJEAN Dominique, Professeur * - Mme MAENHOUDT Cindy, Praticien hospitalier - M. NUDELMANN Nicolas, Maître de conférences DEPARTEMENT DES PRODUCTIONS ANIMALES ET DE LA SANTE PUBLIQUE (DPASP) Chef du département : M. MILLEMANN Yves, Professeur - Adjoint : Mme DUFOUR Barbara, Professeur UNITE D’HYGIENE QUALITE ET SECURITE DES ALIMENTS UNITE DE REPRODUCTION ANIMALE - M. AUGUSTIN Jean-Christophe, Professeur - Mme CONSTANT Fabienne, Maître de conférences* - M. BOLNOT François, Maître de conférences * - M. DESBOIS Christophe, Maître de conférences (rattaché au DEPEC) - M. CARLIER Vincent, Professeur - Mme MASSE-MOREL Gaëlle, Maître de conférences contractuel - M. MAUFFRE Vincent, Assistant d’enseignement et de recherche contractuel UNITE DES MALADIES CONTAGIEUSES - Mme EL BAY Sarah, Praticien hospitalier - Mme DUFOUR Barbara, Professeur* - Mme HADDAD/HOANG-XUAN Nadia, Professeur UNITE DE ZOOTECHNIE, ECONOMIE RURALE - Mme PRAUD Anne, Maître de conférences - M. ARNE Pascal, Maître de conférences - Mme RIVIERE Julie, Maître de conférences contractuel - M. BOSSE Philippe, Professeur* - Mme DE PAULA REIS Alline, Maître de conférences contractuel UNITE DE PATHOLOGIE DES ANIMAUX DE PRODUCTION - Mme GRIMARD-BALLIF Bénédicte, Professeur - M. ADJOU Karim, Maître de conférences * - Mme LEROY-BARASSIN Isabelle, Maître de conférences - M. BELBIS Guillaume, Assistant d’enseignement et de recherche contractuel - M. PONTER Andrew, Professeur - M. MILLEMANN Yves, Professeur - Mme WOLGUST Valérie, Praticien hospitalier - Mme RAVARY-PLUMIOEN Bérangère, Maître de conférences - Mme ROUANNE Sophie, Praticien hospitalier DEPARTEMENT DES SCIENCES BIOLOGIQUES ET PHARMACEUTIQUES (DSBP) Chef du département : M. CHATEAU Henry, Professeur - Adjoint : Mme PILOT-STORCK Fanny, Maître de conférences UNITE D’ANATOMIE DES ANIMAUX DOMESTIQUES UNITE D’HISTOLOGIE, ANATOMIE PATHOLOGIQUE - M. CHATEAU Henry, Professeur* - Mme CORDONNIER-LEFORT Nathalie, Maître de conférences* - Mme CREVIER-DENOIX Nathalie, Professeur - M. FONTAINE Jean-Jacques, Professeur - M. DEGUEURCE Christophe, Professeur - Mme LALOY Eve, Maître de conférences contractuel - Mme ROBERT Céline, Maître de conférences - M. REYES GOMEZ Edouard, Maître de conférences UNITE DE BACTERIOGOLIE, IMMUNOLOGIE, VIROLOGIE UNITE DE MANAGEMENT, COMMUNICATION, OUTILS SCIENTIFIQUES - M. BOULOUIS Henri-Jean, Professeur* - Mme CONAN Muriel, Professeur certifié (Anglais) - Mme LE PODER Sophie, Maître de conférences - M. DESQUILBET Loïc, Maître de conférences (Biostatistiques, épidémiologie)* - Mme LE ROUX Delphine, Maître de conférences - Mme FOURNEL Christelle, Maître de conférences contractuel (Gestion et - Mme QUINTIN-COLONNA Françoise, Professeur management) UNITE DE BIOCHIMIE UNITE DE PHARMACIE ET TOXICOLOGIE - M. BELLIER Sylvain, Maître de conférences* - Mme ENRIQUEZ Brigitte, Professeur - Mme LAGRANGE Isabelle, Praticien hospitalier - M. PERROT Sébastien, Maître de conférences - M. MICHAUX Jean-Michel, Maître de conférences - M. TISSIER Renaud, Professeur* DISCIPLINE : EDUCATION PHYSIQUE ET SPORTIVE UNITE DE PHYSIOLOGIE ET THERAPEUTIQUE - M. PHILIPS Pascal, Professeur certifié - Mme COMBRISSON Hélène, Professeur - Mme PILOT-STORCK Fanny, Maître de conférences DISCIPLINE : ETHOLOGIE - M. TIRET Laurent, Professeur * - Mme GILBERT Caroline, Maître de conférences UNITE DE GENETIQUE MEDICALE ET MOLECULAIRE - Mme ABITBOL Marie, Maître de conférences - M. PANTHIER Jean-Jacques, Professeur* * responsable d’unité REMERCIEMENTS Au Professeur de la faculté de médecine Créteil, Qui nous fait l’honneur d’être notre président de jury de thèse, Sincères remerciements À M. Luca ZILBERSTEIN, Qui nous a fait l’honneur d’être notre directeur de thèse et de nous encadrer dans ce travail tout au long de l’année, Hommages respectueux À M. Renaud TISSIER, Qui nous a fait l’honneur d’accepter l’assessorat de cette thèse, Sincères remerciements À Mlle Rocio FERNANDEZ, Pour son encadrement, ses conseils et sa bonne humeur tout au long de l’année, Toute notre reconnaissance TABLE DES MATIERES TABLE DES MATIERES ________________________________________________________________________ 1 LISTE DES ANNEXES ___________________________________________________________________________ 3 LISTE DES FIGURES ____________________________________________________________________________ 4 LISTE DES TABLEAUX _________________________________________________________________________ 6 LISTE DES ABREVIATIONS ___________________________________________________________________ 7 INTRODUCTION ________________________________________________________________________________ 9 I – Partie BiBliographique __________________________________________________________________ 11 A) OvariectoMie et douleur associée ____________________________________________________________ 11 1 - Technique chirurgicale employée au Centre Hospitalier Vétérinaire Universitaire d’Alfort (CHUVA) __________________________________________________________________________________ 11 a. Positionnement de l’animal __________________________________________________________________________ 11 b. Temps chirurgical _____________________________________________________________________________________ 11 2 - La douleur et ses voies de conduction _______________________________________________________ 12 a. Définition et classifications de la douleur ___________________________________________________________ 12 b. Les voies de la douleur _______________________________________________________________________________ 13 c. La douleur pathologique ______________________________________________________________________________ 14 3 - Pourquoi traiter la douleur ? _________________________________________________________________ 15 a. La douleur pathologique et ses conséquences ______________________________________________________ 15 b. L’ovariectomie, une intervention sans douleur ? ___________________________________________________ 17 c. La prise en compte de la douleur chirurgicale en France __________________________________________ 17 4 - Reconnaître la douleur ________________________________________________________________________ 18 a. Modifications cliniques _______________________________________________________________________________
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