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Our Mission Connect with Us Take Action! OUR MISSION TAKE ACTION! GRIN2B Foundation™ is a parent- Join the registries: founded organization dedicated to We encourage GRIN2B families to take furthering research on the GRIN2B part in various patient registries as more gene and providing support and data will help research. Please refer to education to the small, but growing our website for more information. community of individuals and families ™ impacted by a GRIN2B diagnosis. Spread Awareness: Celebrate GRIN2B Awareness Month Our objectives are to: with us in March! Please follow our social media FOSTER communication, offer pages during this month to learn encouragement and provide facts about GRIN2B and get to know resources to families. our community members! Sharing our Awareness posts will bring visibility FACILITATE the development of an and more understanding to this international patient registry program. ultra-rare condition. support PARTNER with researchers through fundraising and grants to develop Fundraise: research awareness potential treatments and gain a We organize fundraisers throughout better understanding of a GRIN2B the year to help support our mission. diagnosis. Please reach out to us for ways to help or if you are interested in organizing RAISE the profile of this extremely your own fundraiser. rare diagnosis through the creation of a public awareness campaign. Donations: GRIN2B Foundation maintains minimum operating expenses and our Board of Directors is a group of committed CONNECT WITH US volunteers. Your generous donation brings us one step closer to finding www.grin2b.com effective treatments and, one day, a cure. Donations are appreciated grin2b grin2b grin2bfoundation online or can be mailed to: syndrome GRIN2B Foundation PO Box 481223 Email: [email protected] Niles, IL 60714 WWW.GRIN2B.COM BLOG: http://grin2b.com/index.php/blog/ Connect in private: GRIN2B Parent Support Group (closed group for parents/caregivers only) GRIN2B Foundation™ is a registered 501(c)3. Donations are tax deductible. EIN 82-1499966 WHAT IS GRIN2B? SYMPTOMS OF TREATMENTS GRIN2B-RELATED GRIN2B is a gene located While there is currently no NEURODEVELOPMENTAL on the short arm (called “p”) cure for GRIN2B-Related of the 12th chromosome at DISORDER* Neurodevelopmental 12p13.1. It is one member of a family of Disorder, physical, occupational, Most individuals present with: 7 genes: GRIN1, GRIN2A, GRIN2B, and speech therapies can help GRIN2C, GRIN2D, GRIN3A, and GRIN3B. Hypotonia (low muscle tone) manage symptoms in children These genes encode proteins that Speech delays / non-verbal and also help them reach together form a receptor responsible Cognitive disabilities developmental for sending chemical messages Gross and fine motor disabilities milestones. Epilepsy, between neurons in the brain. if present, is treated by a specialist. Co-occurring diagnoses: A variation on the GRIN2B gene Intellectual Disability means that some portion of this At this time, there is no cure and Autism Spectrum Disorder specific genetic code either got no FDA-approved medications to deleted, duplicated or rearranged which Sensory Processing Disorder specifically treat the disorder. impacts the way the brain functions. ADHD Epilepsy GRIN2B Foundation is These changes are referred to as GRIN2B- working to partner with Related Neurodevelopmental Disorder. clinicians, researchers *Not all individuals present with all symptoms and other GRIN-gene patient For a full list of symptoms, please visit organizations to build a http://grin2b.com/index.php/about-grin2b/ collaborative research network to help change the future Males and females of all races can be for all those diagnosed born with a GRIN2B variation. Hundreds with GRIN2B-Related of individuals have been diagnosed Neurodevelopmental Disorder. worldwide. As genetic testing becomes more available, we expect that this number will continue to rise..
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