Crohn S in Childhood Research Association

children and young adults with crohns and colitis

CROHN’S IN CHILDHOOD RESEARCH ASSOCIATION Parkgate House, 356 West Barnes Lane, Motspur Park, Surrey KT3 6NB Tel: 020 8949 6209 website: www.cicra.org e-mail: [email protected] Reg.Charity Nos 278212 & SC040700

PROJECT GRANT Guidance Notes

Applications are invited from Departments wishing to undertake scientific and/or clinical research that must be relevant / involve children with Inflammatory Bowel Disease. These grants are awarded to support either individual projects (e.g. pilot studies, novel or innovative proposals), or they may go towards part-funding larger studies.

Project Grants are awarded for 1 or 2 years, to a maximum total award of £100,000 and paid in stage payments as agreed with CICRA.

All applications must include a paediatric gastroenterologist as co-applicant.

Applications should be made by the proposed Principal Investigator/Supervisor through their Head of Department and sent electronically to [email protected] by 12 noon Friday 14th October 2016. All pages of the application must be put together into one PDF document and clearly titled with the applicants name and institution. Receipt of applications will be acknowledged, but if the application is not in the correct format it will not be considered for funding.

All applications will undergo independent peer review.

Any queries relating to the submission of an application must be referred in the first instance to the CICRA Grants Administrator at the above address who will liaise with the CICRA Trustee(s) responsible for grants. Applicants must not contact a member of the CICRA Awards Advisory Panel to discuss any aspect of an application or the decision reached.

CICRA Project Grant Sept 2013 children and young adults with crohns and colitis

PROJECT GRANT Conditions of Acceptance

In accordance with the Charity Commission’s principles governing the funding of medical research by charities, grants made by CICRA are conditional upon the following:

 If a one-year grant is awarded, a short report for the CICRA Trustees and Medical Advisory Panel will be required at 6 months (max 300 words), with a more detailed final report at the end of the funding period (max 500 words). For a two-year grant, a detailed report will be required at 12 months (max 500 words) and then a final report on completion of the two-year funding period (max 1000 words).

 One short report per year (300 – 500 words), in lay language, will be required for inclusion in the annual CICRA Newsletter.

 The award holder and/or the supervisor may be asked to attend the CICRA annual meeting to give a short presentation on the project.

 Any papers published as a result of the project grant must acknowledge the support of Crohns in Childhood Research Association. Copies of published papers resulting from the PhD Studentship must be sent to the CICRA office soon after publication. Any media interest resulting from the project and its conclusions should be discussed in advance with CICRA and CICRA’s role should be included in any resultant media contact.

 CICRA accepts that Intellectual Property Rights are held by the Institution carrying out the research. However, if the research is funded solely by CICRA, there is an expectation that some of the financial benefit of any commercial proceeds would be shared with CICRA who must be kept informed.

Upon granting the award Full Terms and Conditions will be sent and must be signed by all concerned. Failure to fulfil these grant conditions may result in immediate termination of the grant and/or jeopardise future grant applications.

CICRA Project Grant Sept 2013 children and young adults with crohns and colitis

PROJECT GRANT Application Form

1. Name of Applicant(s): 2. 3. 4.

1. Present Post(s): 2. 3. 4

Institution, Department and Address:

Tel, Fax & email:

Title of Project:

Period for which support sought:

Proposed starting date:

CICRA Project Grant Sept 2013 Grant requested for:

Research Assistant:

Running Expenses:

Equipment:

Other: specify ______

Total ______

Details of Application for Project Grant

Proposed Project background ______A1. Brief summary of project in lay terms (maximum of 150 words)

A2. Has this project been submitted for funding elsewhere? Yes No If Yes, please give details including the decision or expected date of outcome.

______A3. Please attach a detailed description of the project and should cover the following areas:

 Background to the proposal  the work to be undertaken, including the hypothesis behind the study, a brief description of the methods to be employed e.g. study design, patient/sample numbers and analysis  anticipated project ‘milestones’ (simple flow diagram can be used)

CICRA Project Grant Sept 2013  description of the project  description of how the project will significantly advance the body of knowledge of inflammatory bowel disease, particularly but not exclusively as it affects children and young adults  list of appropriate references

Ideally this section should be no more than 3 sides of A4 in length, using 1.5 line spacing and 11 point arial type

______A4. Describe how the project will meet the aims of the Charity.

A5. Give a justification of the funding that you seek for the project. In the case of part funding please give details of the source(s) and amount of the funding sought elsewhere

______

Applicants background

B1. Name, address and other details for Prospective Principal/Lead Investigator/Supervisor

Surname: Date of Birth: Forenames:

Address:

Telephone/Fax/Email:

Degrees and Diplomas (subject, class, university and dates):

______Current post:

Date from:

CICRA Project Grant Sept 2013 Title of post:

Institution:

Department:

Principal employer:

______Previous Posts held (with dates please list no more than 3 with most recent first):

______Recent Grant awards:

______Most recent relevant publications (please list no more than 5 and give citation in full):

______Relevant Training:

______B2. Name, address and details of Co Applicant (incl. telephone/fax and email) (Note: If there are further Co Applicants copy/paste this section of application form as required and add additional applicant’s details and reference as B2a, etc in next pages of application forms )

Surname: Date of Birth:

Forenames:

Address:

Telephone/Fax/Email:

Degrees and Diplomas (subject, class, university and dates):

______Current post:

Date from: Title of post: Institution: Department:

CICRA Project Grant Sept 2013 Principal employer: ______Previous Posts held (with dates please list no more than 3 with most recent first):

______Recent Grant awards:

______Most recent relevant publications (please list no more than 5 and give citation in full):

Relevant Training:

Note: Please Copy/Paste headers from B2 if further Co-Applicants and reference as B2a, et seq

______B3. Names and addresses of two professional referees (not connected with project)

C. Ethics & Regulatory Considerations ______Please answer the following regarding the use of animals

C1. Experiments on animals Will the proposed project involve the use of animals? Yes No

Does your proposal involve the use of animal tissue? Yes No

Do your proposals include procedures to be carried out on animals in the UK which will require a Home Office Licence ? Yes No

CICRA Project Grant Sept 2013 Do your proposals involve the use of animals or animal tissue outside of the UK? Yes No

If Yes at C5 questions above, have personal and project licences been granted by the Home Office? . Yes No If Yes, please enter licence details here:

If No, please indicate when this is to happen and submit licence details to CICRA.

If animal species to be used: please indicate which species from: Cat, Dogs, Horses, non-human Primates, Genetically altered animals and for any other animal(s). Please indicate here:

Explain why the use of animal(s) is necessary and whether there are other possible approaches; please include severity of procedures to be used. A brief justification (attach one size A4 maximum) must be provided outlining the type and numbers of animals to be used, the source of animals and how they will be transported and maintained, and evidence that the species chosen is appropriate and that the minimum number used will give statistically valid results.

Please note: a) Licence details must be sent to CICRA before successful applicant’s Institution receives CICRA funding. b) In some cases CICRA may need to seek additional animal related information from the applicant. c) CICRA funded research should conform to the 3Rs principles and the National Centre for Replacement, Refinement and Reduction of Animals in Research (NC3Rs) Guideline ______C2. Does the project involve any experiments with genetically modified organisms or does it involve the use of genetic manipulation techniques? (If yes, please explain) Yes No

______C3. Is the proposed research likely to lead to patentable or Yes No commercially exploitable results? (If yes please explain)

______C4. Will the proposed project involve patients/human? subjects OR patient material/samples? Yes No

If Yes, how many patients/subjects will be involved in total?

Please give status of ethical committee approval (ring where appropriate):

UNNECESSARY TO BE SUBMITTED PENDING APPROVED

Please attach written approval as granted by your Ethics Committee (if appropriate)

CICRA Project Grant Sept 2013 If approval UNNECESSARY, please state why

Please note that: If ethics approval is pending at the time of application, funding (although not an award decision in principle) remains conditional on this being secured and CICRA will not award any Fellowship until the Trustees are in receipt of a copy of the full transcript of the relevant ethics committees’ written confirmation of approval.

Project Grant Declaration

We have read the CICRA Project Grant application criteria and in the event of a grant being awarded agree to abide by them and any amendments that may subsequently be issued. I/we shall be actively engaged in, and in day-to-day control of, the project. CICRA will be informed as soon as I/we hear the outcome of any other applications for funding for the proposed project and/or any significant changes to this proposal.

Contact telephone/extension number of Project Investigator/Lead (Direct Line, if possible) ……..…………………………………

To be signed by: Signature Name in block capitals Date

HEAD OF DEPARTMENT

PRINCIPAL INVESTIGATOR

This application should be submitted by/through i) the Head of Department and ii) the officer who will be responsible for administering any grant that might be awarded. Ea ch should sign the following declaration:

I confirm that I have read this application and criteria governing the award of a CICR A Project Grant and that, if granted, the work will be accommodated and administere d in the Department/Institution.

(i) Signature of Head of Department (ii) Signature of Administrative Authority

Title: Director Finance Officer Bursar Registrar Secretary

Full Name of Above Full Name of Above

CICRA Project Grant Sept 2013 Institution Address Institution Address, telephone number, and fax number (of department)

CICRA Project Grant Sept 2013