The JAMA Report Video and Multimedia Assets Are Available At s2

REPORT Tuesday, August 18, 2015

The JAMA Report Video and Multimedia Assets are available at http://broadcast.jamanetwork.com

Please call: JAMA Media Relations with any questions: (312) 464-5262

“Teens That Use E-Cigarettes More Likely to Start Smoking”

TEASE RUNS: 05 (girl using e-cigarette, girl smoking cigarette) Could starting this, lead to doing this? Find out next.

JAMA 3993 TRT: 2:03 EMBARGO: 11a.m. (ET) Tuesday, August 18, 2015

**SUGGESTED READER** High school freshmen who tried e-cigarettes were four times more likely to go on to use real tobacco products.

INTRO: Over the past several years, electronic or e-cigarettes have grown in popularity. Today’s e-cigarette users include a growing number of teenagers, many who have never smoked tobacco. A new study looked at whether younger teens that begin using e-cigarettes might also be more likely to experiment with smokable tobacco products. Catherine Dolf explains in this week’s JAMA Report.

1 VIDEO AUDIO

B-ROLL E-CIGARETTES FIRST ENTERED THE MARKET AS AN Man smoking e-cigarette, outside of ALTERNATIVE FOR ADULTS WHO WANTED TO QUIT vap shop SMOKING. BUT OVER THE YEARS, THINGS HAVE CHANGED. SOT/FULL “They come in attractive flavors like cotton candy, Adam M. Leventhal, Ph.D. - bubble gum. They’re very hi-tech and you know, they’re University of Southern California modern and cool.” Super@:08 Runs:09

B-ROLL WHICH HELPS MAKE THEM VERY POPULAR WITH Man holding e-cigarette, Michelle YOUNG PEOPLE. MICHELLE MERCADO, NOW IN HER smoking cigarette, Michelle using 20’S, SMOKES REGULAR CIGARETTES BUT ALSO vape pen STARTED USING E-CIGARETTES IN HER TEENS.

SOT/FULL “I do see a lot of people like high schoolers and like Michelle Mercado - E-cigarette and young adults getting into the whole vape pen and e- Tobacco User cigarette thing.” Super@:25 Run:09 B-ROLL DR. ADAM LEVENTHAL FROM THE UNIVERSITY OF Dr. Leventhal entering room and SOUTHERN CALIFORNIA, KECK SCHOOL OF MEDICINE meeting with his staff, high school AND CO-AUTHORS SURVEYED MORE THAN 23 kids walking, teen smoking HUNDRED LOS ANGELES AREA HIGH SCHOOL STUDENTS AT THE BEGINNING OF 9TH GRADE. STUDENTS INCLUDED IN THE SURVEY ALL REPORTED NEVER USING ANY SMOKABLE TOBACCO PRODUCTS. SOT/FULL “We compared teens who had used e-cigarettes to teens Adam M. Leventhal, Ph.D. - who hadn’t and we looked to see whether there were University of Southern California differences between those two groups and the initiation Super@:49 of smoking of combustible tobacco products.” Runs:13

B-ROLL THESE STUDENTS WERE SURVEYED AGAIN SIX People getting on bus MONTHS LATER AND ALSO WHEN ENTERING 10TH GRADE.

SOT/FULL “The teens who used e-cigarettes were more than four Adam M. Leventhal, Ph.D. - times more likely to start smoking than the teens who University of Southern California hadn’t used e-cigarettes. The associations were Super@1:06 consistent across all the different types of tobacco Runs:17 products, regular cigarettes, cigars or even hookah (Video covering 2nd part of bite: guy tobacco water pipe.” smoking cigarette) GXF FULL THE STUDY APPEARS IN JAMA, JOURNAL OF THE JAMA LOGO AMERICAN MEDICAL ASSOCIATION.

SOT/FULL “They were more likely to use two or more products for Adam M. Leventhal, Ph.D. - the first time during high school in comparison to teens University of Southern California who hadn’t used e-cigarettes.” Super@1:27 Runs:10 2 B-ROLL THIS TREND CONTINUED AS THE STUDENTS ENTERED Students walking and girl on bike, 10TH GRADE. EVEN WHEN ADJUSTING FOR OTHER girl smoking cigarette FACTORS LIKE PEER PRESSURE, IMPULSIVE TAG: THIS WAS AN OBSERVATIONAL STUDY. FURTHER RESEARCH IS NEEDED TO DETERMINE WHETHER THE ASSOCIATION BETWEEN E-CIGARETTE USE AND SUBSEQUENT SMOKING IS CAUSAL.

Please see the complete study for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

TO CONTACT: Dr. Adam Leventhal call Leslie Ridgeway at: (323) 442-2823

ADDITIONAL SOUNDBITES:

Adam M. Leventhal, Ph.D. - University of Southern California

QUOTE 1 Runs:16 “If they’re inhaling nicotine and they enjoy the experience of inhaling nicotine via the e-cigarette, it’s possible that they might be more open to experimenting with smokable tobacco products in the future.”

QUOTE 2 Runs:13 “We didn’t expect to see such consistent associations over and above these well known risk factors that have been implicated in the propensity to start smoking conventional cigarettes in the past.”