Curriculum Vitae s318

CURRICULUM VITAE

Name: Hamisi Masanja Malebo Date of birth 8th February 1967 Place of birth Sengerema District, Mwanza Region Nationality Tanzanian Marital status Married with two children: son and daughter

Physical Address: Department of Traditional Medicine Research, National Institute for Medical Research, Plot 2448 Ocean Road/Luthuli Street, P.O. Box 9653, Dar es Salaam, Tanzania. Mobile: +255762377307; +255652828184 Email: [email protected]; [email protected]

Current Position: Principal Research Scientist/Head of Department Department Traditional Medicine Research and Development Area of Specialization: Medicinal Phytochemistry/Pharmacochemistry;

Degrees/Diplomas: PhD (Medicinal Phytochemistry), 2009, Sandwich program between Kenyatta University, Kenya & University of Basel, Switzerland. MSc (Natural Products Chemistry), 2000, University of Dar es Salaam, Tanzania. BSc (Chemistry/Biology/Education), 1996, University of Dar es Salaam, Tanzania. Dip. Ed (Chemistry/Biology/Education), 1990, Mkwawa Teachers College, Tanzania.

SCIENTIFIC RESEARCH VISITS 2013 – 2014: Visiting Research Scientist: South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, China. 2006 -2007: Visiting Research Scientist: Pharmaceutical Biology (PharmBio) Research Group, Department of Pharmaceutical Sciences, University of Basel, Switzerland. 2004 -2005: Visiting Research Scientist: Parasite Chemotherapy Research Group, Swiss Tropical Institute, Basel, Switzerland.

RESEARCH & TEACHING INTERESTS: Parasite and Microbial Chemotherapy, Nutritional Chemistry, Environmental Chemistry and Biotechnology, Medicinal Phytochemistry, Analytical chemistry, Nano-Medicine, Pharmaceutical Technology & Drug Metabolism and Pharmacokinetics.

PUBLICATIONS: 2014

1 1. Peter, E., Mashoto, K.O., Rumisha, S.F., Malebo, H.M., Shija, A and Oriyo N. (2014). Iron and Ascorbic Acid Content in Hibiscus sabdariffa calyces in Tanzania: Modeling and Optimization of Extraction Conditions. International Journal of Food Science and Nutrition Engineering, FOOD-106900077, Accepted. 2. Omole, R.A., Gathirwa, J., Akalla, H.O., Malebo, H.M., Machocho, A.K., Hassanali, A and Ndiege, I.O. (2014). Bisbenzylisoquinoline and hasubanane alkaloids from Stephania abyssinica (Dillon & A. Rich) (Menispermeceae). Phytochemistry, PHYTOCHEM-D-13-00664R2, Accepted. 3. Malebo, H.M., Jonker, S.A., Waibel, R and Nkunya, M.H.H. (2014). Diprenylated indole alkaloids from fruits of Hexalobus monopetalus. Natural Products and Bioprospecting, NPAB-D-14-00017R2, (DOI) 10.1007/s13659-014-0010-x, Accepted. 4. Mohamed, H., Brown, J., Mussa, R., Clasen, T., Malebo, H.M. and Mbuligwe, S. (2014). Point of Use Chlorination of Turbid Water in Tanzania. Journal of Water and Health, JWH-D-14-00001, Accepted. 5. Rubaka, C., Shahada, F., Ndakidemi, P and Malebo, H. (2014). Analysis of Phytochemical and Antibacterial Activity of Carissa spinarum Linn Crude Extracts. European Journal of Medicinal Plants, 2013/EJMP/8236, Accepted. 6. Malebo, H.M., Kihampa, C., Mgina, C.A., Sung’hwa, F., Waibel, R., Jonker, S.A. and Nkunya, M.H.H. (2014). Antifungal enantiomeric styrylpyrones from Sanrafaelia ruffonammari and Ophrypetalum odoratum. Natural Products and Bioprospecting, NPAB-D-14-00025R1, Accepted.

2013 7. Malebo, H.M., Wenzler, T., Cal, M., Swaleh, S.M., Hassanali, A., Machocho, A.K., Séquin, U., Häussinger, D., Dalsgaard, P., Omolo, M.O., Hamburger, M., Brun, R. Ndiege, I.O. (2013). Anti-protozoal and structure-activity relationships of chemical constituents of Acridocarpus chloropterus Oliver (Malpighiaceae) from Tanzania. International Journal of Natural Products Research, 3(4), 74-81. http://www.urpjournals.com 8. Mashoto, K.O., Mubyazi, G.M., Makundi, E., Mohamed, H and Malebo, H.M. (2013). Estimated risk of HIV acquisition and practice for preventing occupational exposure: a study of healthcare workers at Tumbi and Dodoma Hospitals, Tanzania. BMC Health Services Research, 13:369; http://www.biomedcentral.com/1472-6963/13/369 9. Malebo, H.M., Imeda, C., Kitufe, N.A., Katani, S.J., Sunguruma, R., Magogo, F., Tungu, P.K., Nyigo, V.A., Wiketye, V., Mwaiko, G.L., Ogondiek, J.W., Mbogo, G.P., Mhame, P.P., Matata, D.Z., Malima, R., Magesa, S.M., Massaga, J.J., Malecela, M.N. and Kitua, A.Y. (2013). Repellence effectiveness of essential oils from some Tanzanian Ocimum and Hyptis plant species against afro-tropical vectors of malaria and lymphatic filariasis. J. Med. Plants Res. 7(11), 653-660. http://www.academicjournals.org/JMPR, DOI:10.5897/JMPR012.732. 10. Mashoto, K.O., Mubyazi, G.M., Mohamed, H and Malebo, H.M. (2013). Self-reported occupational exposure to HIV and factors influencing its management practice: a study of healthcare workers in Tumbi and Dodoma Hospitals, Tanzania. BMC Health Services Research, 13:276. http://www.biomedcentral.com/1472-6963/13/276 11. Malebo, H.M., Wenzler, T., Cal, M., Swaleh, S.M., Omolo, M.O., Hassanali, A., Séquin, U., Häussinger, D., Dalsgaard, P., Hamburger, M., Brun, R. Ndiege, I.O. (2013). Anti-protozoal activity of aporphine and protoberberine alkaloids from Annickia kummeriae (Engl. & Diels) Setten & Maas (Annonaceae). BMC Complementary and Alternative Medicine, 13:48. http://www.biomedcentral.com/1472-6882/13/48 2012 12. Omolo, J.J., Maharaj, V., Naidoo, D., Klimkait, T., Malebo, H.M., Mtullu, S., Lyaruu, H.V.M and de Koning, C.B. (2012). A bioassay-guided investigation of the Tanzanian plant Pyrenacantha kaurabassana Baill for potential anti-HIV active compounds. Journal of Natural Products. 75(10):1712-1716 , PMID 23002902 13. Exavery, A., Mubyazi, G.M., Rugemalila, J., Mushi, A.K., Massaga, J.J., Malebo , H.M., Tenu, F., Ikingura, J.J., Malekia, S., Makundi, E.A., Ruta, A.M., Ogondiek, J.W., Wiketye, V. and N Malecela, M.N. (2012). Acceptability of condom promotion and distribution among 10-19 year-old adolescents in Mpwapwa and 2 Mbeya rural districts, Tanzania. BMC Public Health, 12:569. http://www.biomedcentral.com/1471- 2458/12/569 14. Mubyazi, G.M., Aziza J. Mwisongo, A.J., Makundi, E.A., Pallangyo, K., Malebo, H.M., Jonathan M. Mshana, J.M., Senkoro, K.P., Kisinza, W.N., Ipuge, Y., Hiza, P., Magesa, S.M., Kitua., A.Y. & Mwele N. Malecela, M.N. (2012). Analysis of Cost Impact of HIV/AIDS on Health Service Provision in Nine Regions, Tanzania: Methodological Challenges and Lessons for Policy. Rwanda journal of health sciences, 1(1): 8-20. 15. Malebo, H.M., Makundi, E.A., Massaga, J.J. and Cavill, S. (2012). Outcome and impact monitoring for scaling up Mtumba Sanitation and Hygiene Participatory Approach in Tanzani a. Dar es Salaam, Elite Prepress Limited., ISBN: 978-9976-89-232-1 2011 16. Graz, B., Kitua, A.Y. & Malebo, H.M. (2011). To what extent can traditional medicine contribute a complementary or alternative solution to malaria control programmes? Malaria Journal 10 (Suppl 1):S1 - 6. 2010 17. Kidukuli, A.W., Mbwambo, ZH., Malebo, H.M., Mgina, C.A. and Mihale, M.J. (2010). In vivo antiviral activity, protease inhibition and brine shrimp lethality of selected Tanzanian wild edible mushrooms. Journal of Applied Biosciences. 31: 1887–1894. 18. Mwangi, E.S.K., Keriko, J.M., Machocho, A.K., Wanyonyi, A.W., Malebo, H.M., Chhabra, S.C. and Tarus, P.K. (2010). Antiprotozoal activity and cytotoxicity of metabolites from leaves of Teclea trichocarpa. Journal of Medicinal Plants Research Vol. 4(9), 726-731. 2009 19. Malebo, H.M., Tanja, W., Cal, M., Swaleh, S.M., Omolo, M.O., Hassanali, A., Séquin, U., Hamburger, M., Ndiege, I.O. and Brun, R (2009). Anti-plasmodial, anti-trypanosomal, anti-leishmanial and cytotoxicity activity of selected Tanzanian medicinal plants. Tanzania Journal of Health Research 11(4), 226-234. 2008 20. Massaga, J.J., Lusingu, J.P., Makunde, R., Malebo, H.M., Chile, M.M., Akida, J.A., Lemnge, M.M., Rønn, A.M., Theander, T.G., Bygbjerg, I.C., and Kitua, A.Y. (2008). Biological and haematological safety profile of oral amodiaquine and chloroquine in healthy volunteers with or without Plasmodium falciparum infection in northeast Tanzania. Tanzania Journal of Health Research, 10(3), 144-150. 2007 21. Makundi, E.A., Mboera, L.E.G., Malebo, H.M. and Kitua, A.Y. (2007). Priority Setting on Malaria Interventions in Tanzania: Strategies and Challenges to Mitigate Against the Intolerable Burden Am. J. Trop. Med. Hyg., 77(Suppl 6), 106–111. 2006 22. Makundi, E.A., Malebo, H.M., Mhame, P., Kitua A.Y. and Warsame, M. (2006). Role of traditional healers in the management of severe malaria among children below five years of age: the case of Kilosa and Handeni Districts, Tanzania. Malaria Journal 5:58. 23. Lugimbana L., Malebo H. M., Segeja M. D., Akida J. A., Malle L. N. (2006). A simple technique for the detection of antimalarial drug formulations and their presence in human urine. Tanzania Health Research Bulletin, 8 (3): pp. 149 – 154. 2005 24. Malebo, H.M., Nguruwe, R., Lugimbana, L., Sambu, E., Malecela, E., Kamugisha, M.L., Senkoro, K. & Magesa, S.M. (2005). Efficacy of Ocimum suave volatile oil formulation against man-biting mosquitoes in Muheza, north-east Tanzania. Tanzania Health Research Bulletin 7, 25-30. 25. Odalo, J.O., Omolo, M.O., Malebo, H.M., Angira, J., Njeru, P.M., Ndiege, I.O. and Hassanali, A. (2005). Repellency of essential oils of some plants from the Kenyan coast against Anopheles gambiae. Acta Tropica 95, 210-218.

3 26. Nyigo, V.A and Malebo, H.M. (2005). Drug discovery and developments in developing countries: bottlenecks and way forward. Tanzania Health Research Bulletin 7(3), 154-158. 2004 27. Kitua, A.Y., and Malebo, H.M. (2004). Malaria Control in Africa and the Role of Traditional Medicine. In: Traditional Herbal Medicines for Modern Times: Traditional Medicinal Plants and Malaria. Edited by: Willcox M., Rasoanaivo P. & Bodeker G. CRC Press LLC, Washington, D.C. Part 1, page 3-18. 2002 28. Kisinza W., Mwisongo A., Makundi E., Mubyazi G., Senkoro K., Magesa S., Malebo H., Mcharo J., Hiza P., Pallangyo., Ipuge Y., Kitua A, Malecela-Lazaro M. (2002). Stigma and Discrimination on HIV/AIDS in Tanzania. Tanzania Health Research Bulletin 4,(2), 42. 2001 29. Magesa, S.M., Mboera, L.E.G., Mwisongo, A.J., Kisoka, W.J., Mubyazi, G.M., Malebo, H.M., Senkoro, K.P., Mcharo, J., Makundi, E.A., Kisinza, W.N., Mwanga, J., Mushi, A.K., Hiza, P., Malecela-Lazaro, M.N. and Kitua, A.Y. (2001). Major Health Problems in Some Selected Districts of Tanzania. Tanzania Health Research Bulletin 3(2), 10. 2000 30. Malebo, H.M., Nkunya, M.H., Jonker, S.A (2000). Antimalarial potential of herbal medicines used in the treatment of malaria in Tanzania. American Journal of Tropical Medicine and Hygiene, 62 (3; Suppl), 434