Name: Younis Mohamed Al Hassan Younis

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Name: Younis Mohamed Al Hassan Younis

Younis Detailed C.V. (This CV has not been up-dated or revised)

Personal Background

Name :Younis Mohamed El-Hassan Younis.

Nationality: Sudanese

Religion : Islam.

Occupation : Full Professor of Organic Chemistry.

Specializations: Organic Chemistry.

Teaching Experience: 30 years experience in university teaching at 10 universities in different countries.

…………………………………………………………………

Postal Address

Prof. Dr.Younis M.H. Younis Department of Pharmaceutical Chemistry Faculty of Pharmacy University of Medical Sciences and Technology P.O. Box Khartoum Sudan ------E-mail: [email protected]

Mobile Phone: (00 249) 9126 43153 ……………………………………………………………………..

1 Contents of the CV

Page No. Personal Background……………………. 1

Academic Background…………………… 3

Professional History……………………... 4

Administrative & Academic Positions…... 9

Publication of Teaching Materials……..... 10

Seminars, Conferences & Workshops……. 11

Supervision of Research Projects………… 12

Published Research Papers & Articles…… 13

Documented Unpublished Research Work.. 14

Research Projects in Progress……………. 15

Implemented Project Proposals………….. 16

Teaching Experiences in Universities 17

*Attachment: List of Courses Instructed in Different Universities.

Academic Background: Degrees, Certificates & Awards:

2 1. Sudan School Certificate, Division One, Ministry of Education, 1968, Sudan.

2. B.Sc. (General), Distinction in Chemistry and Merit in Botany, University of Khartoum, 1972, Sudan.

3. B.Sc. (Honours), Division One, Second Class, University of Khartoum, 1973, Sudan.

4. University Prize for Best Graduate in the year 1973, University of Khartoum, Sudan.

5. M.Sc. Degree, Organic Chemistry, University of Khartoum, 1976, Sudan (Passed without further examination)

6. Certificate: Spectroscopic Interpretation of Organic Molecules, University of Manchester Institute of Technology, (UMIST) 1979, United Kingdom.

8. Ph.D. Degree, Synthesis of Natural Products, University of Cambridge, 1981, United Kingdom.

9. Certificate: Chemistry of Medicinal Plants, International Science Program in Chemistry, University of Uppsala, Department of Pharmacognosy, Faculty of Pharmacy, Biomedical centre (BMC), 1983-1985, Sweden..

10. The Crystal Glass Stamp Award of the University of Uppsala for the Best African Research Fellow 2003. ……………………………………………………………….. (Academic certificates, awards & documents confirming the information cited on this C.V. could be provided on request).

Professional History:

3 (Certificates are available for all information cited below)

July 1973: Appointed in the post of Teaching Assistant at the Department of Chemistry, Faculty of Science, University of Khartoum, Sudan. (Teaching duties are listed in the attachment).

1973-1978: Part-time Teaching of Chemistry at the Faculty of Education, University of Khartoum. (Certificate available)

1975, 1976, and 1977: Chosen member of Sudan School Certificate Examination Control Board.

Sept.1978- Nov. 1981 British Council Scholarship for Ph.D. Degree in the synthesis of natural products, University of Cambridge, UK.

January 1982-Sept. 1984: Assistant Professor of organic Chemistry (Natural Products), Department of Applied Chemistry & Chemical Technology, Faculty of Science & technology, Un iversity of Gezira, Sudan (Certificate available). Beside my teaching responsibilities, I carried out the following assignments: i. Chemical Laboratories Coordinator. Duties include strengthening the laboratory facilities and implementing laboratory management and policies.

ii. Member of the Faculty Board.

iii. The Faculty Timetable Officer.

iv.University Library Committee Member.

v. Secretary of Committee for the Evaluation of the Degree Structure (Curriculum) of the Faculty of Science & Technology (Please see University certificate).

1984-1985: Research Fellowship at the Department of Pharmacognosy, Biomedical Centre, University of Uppsala, Sweden. (Please see Department & Swedish International Seminars Certificates).

1984-1985: Elected Chairman of the Natural Products Research Network for Eastern & Central Africa (NAPRICA) Sweden Branch.

July-September 1985: Research Work in SANDOZ Pharmaceutical Laboratories, Basil, Switzerland. Subject (Extraction of Pharmacologically Active Components of Sudanese Medicinal Plants).

September 1985- 1987: Held the position of Head, Department of Applied Chemistry & Chemical Technology, Faculty of Science &Tech nology, University of Gezira, Sudan (Please see University certificate).

4 1985-1987: Secretary of Committee for the Technical & Financial Support of the Faculty of Science & Technology. The committee has succeeded in securing pilot plants, equipments, chemicals & glassware from international donors.

October 1987-1989: Appointed in the post of Assistant Professor, University of Sebha, Libya. Duties included beside i. Teaching organic chemistry and natural products for the Colleges of Science and Medicine (Please see the attachment) ii. Evaluation of the chemistry curriculum. iii. Translation (from English into Arabic) a Technical Textbook designed f or Technical Secondary Schools. iv. Coordination of student’s industrial training trips to factories refineries and petrochemical complexes.(Certificate available). v. October 1989: Appointed in the post of Assistant Professor. 7Th April University, Zawia, Libya (Please see University certificate)

Nov. 1992 - Nov. 1994: Held the position of Head, Department of Chemistry, Faculty of Science, 7th April University, Libya. Achievements:

I. Proposal for applied chemistry curriculum (implemented).

ii.Proposal for: Students training program in industrial sites.

iii.Master plan for the new chemistry department.

iv. Job Evaluation and Job Description for supporting staff (teaching assistants, technicians, laboratory assistants, store keepers & secretaries).

v. Designing of storage system for chemicals, glassware and equipments in the university. (See University certificate)..

Jan. 1995 I have been appointed in the post of Associate Professor III, Department of Chemistry, College of Science University of Asmara, Eritrea.

October 1995: Appointed as UNDP (United Nations Development Program) Specialist in the post of Associate Professor and Head, Department of Chemistry at the same university. (Certificates enclosed). The following endeavours have been achieved (Please see University & UNDP certificates).

Jan 1998. Research Fellowship, Department of Pharmacognosy, Biomedical Centre, University of Uppsala, Sweden. The fellowship achieved the following:

5 i. Training Course in Organic Retrosynthesis.

ii. Publication of two research papers.

iii. Establishment of strong link between the University of Asmara Chemistry Department and other Department in Uppsala University (Pharmacognosy, Organic, Inorganic and Toxicology Departments).

Jan 1999-2002 Teaching and research post in King Faisal University, Saudi Arabia. Duties and achievements:

i. Teaching organic and analytical chemistry courses (see attachment).

ii. Research in Natural Products with publication of three research papers (Please see list of publication elsewhere in this manuscript).

iii. Contributed in writing the proposal for the establishment of the College of Science.

iv. Member of Committee for the Evaluation of College of Education Curriculum Development.

v. Member of the Panel for the Improvement of the College Administrative System (Administrative Rules and Regulations).

vi. Committee of Research Enhancement in the Department of Chemistry.

vii. Assigned by the University with another co-author to write a textbook entitled:The Chemistry of Petroleum,Petro-chemicals & Polymer sponsor ed by King Faisal University, Saudi Arabia. Published 2005. Now it is a textbook in all Saudi Arabia Universities. The textbook was reprinted (nd2 edition)in the year 2010

July 2002 to July 2004 Appointed in the post of associate professor (under the World Bank Program) in the Department of Chemistry, College of Science, University of Asmara, Eritrea. Resigned July 2004.

July 2004-Sept. 2005 Appointed in the post of Associate Professor, in the Department of Chemistry in the Eritrean Institute of Science & Technology (EIT).

Sept. 2005 I resigned from the EIT and returned to Sudan.

2005-to-date Part-time teaching professor of organic chemistry in Africa International University. (Please see attachment for the teaching duties).

6 2005-1010 Appointed in the post of professor of organic chemistry in the School of Pharmacy, Ahfad University for Women, Sudan. Beside my teaching duties (Please see attachment). I have been involved in the following assignments

i. Member of the University Senate.

ii. Member of the University Postgraduate Degrees Committee.

iii. Chairman of the College of Pharmacy Examination Committee.

vi. Co-ordinator of the College Of Pharmacy Students Activities in the Sudanese Woman Week. This is a festival and cultural occasion organized by the University every year.

vii. Member of the University Academic Regulation Committee.

viii. Academic Tutor for Batch IV students.

ix. Involved and have been participated in several University Conferences and Workshops.

2010-to-Date Appointed in the post of Professor of organic chemistry in the Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medical Sciences and Technology. Beside my teaching duties in the undergraduate and postgraduate programs I am holding other responsibilities: 1. Coordinator of the pharmaceutical analysis and quality control M.Sc.Degree program.(2010-2013) 2. Managing Director of the University Pharmaceutical Technology and Analytical Chemistry Centre(2011-2013) Now known as Dr Alawia Imam Institute Laboratory. 3. Coordinator of senior undergraduate research projects.(2010-2012) 4. Head of Publication and dispensing Unit in the Institute of Education and Professional Development. (2011-up-to-date). 5. General Manager of Alawia Imam Pharmaceuitical Research and Development Institute (December 2014-to-2016). ------Main Administrative & Academic Positions (1981 to 2011)

1. College Chemical Technology Laboratories Coordinator (1981-82), Faculty of Science & Technology, University of Gezira, Sudan.

2. Head, Department of Applied Chemistry & Chemical Technology (1982-1983 & 1985-1987), Faculty of Science & Technology, University of Gezira, Sudan.

7 3. Head, Department of Chemistry, Zawia University (1989- 1994), Libya.

4. Industrial Training Officer, University of Gezira (1981- 1983), University of Sebha (1987-1989), Zawia University (1989-1994 Libya, University of Asmara (1995-1999). Eritrea.

5. Head, Department of Chemistry (1995-2000), College of Science, University of Asmara.

6. Team Research Leader, Chemistry of Medicinal Plants & Drug Discovery Centre, (1995-1999 & 2002-2004), University of Asmara, Eritrea.

7. Secretary of the College of Science Curriculum Development Committee (1995-1999), University of Asmara Eritrea.

8. Acting Dean for various periods (1982, 1997 & 1999) in some of the above mentioned universities.

9. Director of Curriculum Development & Training Programs (2003- 2005), Institute of Science & Technology, Eritrea.

10. Assistant Dean for Academic Affairs, (2006-to-date), School of Pharmacy, Ahfad University for Women, Sudan.

11. Head, Examination Committee (2007-to-date), School of Pharmacy, Ahfad University for Women, Sudan.

13. Member of Ahfad University Postgraduate Committee (2007-to- date), Ahfad University for Women, Sudan.

14. Co-ordinator of School of Pharmacy for the 100th Anniversary for Education of Women in Sudan (2007).

15. Member of Ahfad University Academic Senate (2006-to- date). Ahfad University for Women, Sudan.

16. Member of Evaluation Committee for the Physiotherapy Curriculum, School of Health Sciences, Ahfad University, 2007.

17. External Examiner for the B. Sc. (honours) Degree examinations and Research Dissertations Oral Examinations 2006/2007; 2008/2009; 2009/2010 and 2010/2011 Batchs. Department of Chemistry, Faculty of Science, University of Khartoum, Sudan.

18. Member of the Organizing Committee for the Workshop entitled: Adoption of Advanced Teaching Methodologies and Safety in Scientific Laboratories, Ahfad University 07.

8 19. Member of the Organizing Committee for the Workshop: Revising Primary School Education in Sudan. Jointly organized by Ahfad University & Ministry of General Education.

20. External Examiner for a Ph.D. Degree Thesis in Medicinal Chemistry, College of Graduate Studies, University of Khartoum, Sudan, May 2008.

21. External Examiner for a number of M.Sc. Degree and PhD. Thesis in Chemistry (University of Khartoum, Sudan University of Science and Technology and International University of Africa)

22. Member of the University Task Force Committee for the implementation of the Credit Hour Evaluation System and the Freshman Program in Ahfad University for Women (2009).

23. Co-ordinator of the Pharmaceutical Analysis and Quality Control M.Sc. Degree Program, Faculty of Pharmacy, University Medical Sciences & Technology, Khartoum Sudan. (2010-2015).

24. Head of Publication and Dispensing Unit in the Institute of Education and Professional Development, University of Medical Sciences and Technology. Duties are : Writing up a proposal and feasibility study for means of publishing the University Medical and Scientific Journal.

25. Managing Director of the UMST-Pharmaceutical Technology and Pharmaceutical Analysis Centre. The establishment of the Centre is in its final stage.

26. External Examiner for Ph. D. Candidate. Sudan University of Science and Technology. Title of Thesis: Effects of some Natural Products on Reduction of Aflatoxins in Peanuts (Analytical Chemistry specialization). Dec. 2012)

27. External Examiner for Ph. D. Candidate. University of Khartoum. itle of Thesis: Physico-chemical Studies of Acetone Successive Fractions from Acacia Senegal Gum. Fe.b 2013.

28. External Examiner for Ph. D. Candidate. University of Science and Technology, Title Development and Validation of Sequential Injection Chromatographic Methods for some Pharmaceutical Drugs. June, 2013.

29. Reviewer of the research article entitled: Sequential Extraction of Mineral Content in Deers Lick Soils in Northern Darfur, Submitted for publication in: Natural and Medical SciencesJournal. Sudan University of Science and Technology (February 2014)

30. Evaluation of Ph. D. Research Proposals entitled:

9 a. Energy Conservation and Environmental Protection in Refineries. March 2014 b. Modelling and Optimization of a Catalyst Reformer in Khartoum Refinery. March 2014

c. Kassala Ground Water Basin Recharge- Kassala State, Sudan. March 2014 Sudan Academy of Sciences. Engineering Research and Industrial Technology Council, Khartoum, Sudan.

31. Co.opt. member of the University of Khartoum Staff Promotion Committee March 2014.

32. General Manager of Alawia Imam Pharmaceutical Research and Development Institute, November 2014 to date.

Many others are not included.

Publication of Teaching Material Preparation and Printing of the following Practical Chemistry Manuals and a theory textbook: i. Techniques in Practical Organic Chemistry. (1995). (Please see list of contents) by Younis M.H. Younis. ii. Organic Preparation & Isolation of Natural Products. (1995). (please see list of contents). By Younis M.H. Younis. iii. Qualitative Organic Analysis. (1996). (Please see list of contents). by Younis M.H. Younis.

iv. Text Book entitled: The Chemistry of Petroleum, Petrochemicals and Polymers (In Arabic language). By Younis Mohamed El-Hassan and Shar S. AlShihry. Sponsored by King Faisal University, Saudi Arabia. Published 2005 And reprinted in 2010. v. The following university level textbooks are in the process of preparation: 1. Industrial Chemistry (surveying selected industries that are suitable for Third World Countries by Younis M.H. Younis.

2. Organic Chemistry Made Simple (Tailored for Pharmacy & Medical Students). By: Younis M.H. Younis

3. Stereochemistry Made Simple. By Younis M.H. Younis Seminars, Symposia, Conferences and Work-shops: A. Seminars & Conferences Attended With Contributions

10 I. Contributions in the Departments of Chemistry Seminars 1. Extraction Procedures of Natural Products: From Plants to Drugs. 2. Estimation of Aflatoxins in Agricultural Products. 3. Pyrones as Natural Products Synthons. 4. Extraction of Agar and Alginic Acid from seaweeds: The Economic Impact. II. Conferences & Workshops Attended with Contributions i. Aflatoxins Contamination in Food & Feed, presented in: The Eritrean Chemical Society 3rd Annual Congress, 1995. ii. Pyrones as Natural Products Synthons, presented in: Eritrean Chemical Society 4th Annual Congress, 1996. iii. Characteristics & Chemical Composition of Cucurbita pepo Seedoil, presented in: Eritrean Chemical Society 5thAnnual Congress, 1998. iv. The Ministry of Education/University of Asmara Joint Workshop to Study the State of High School Education in Eritrea, the following studies have been prepared by: Younis M.H. Younis, R. Murphy & A. M. Rajasab and presented by Younis in the Workshop: 1- Eritrean School Certificate Examinations: Review and Evaluation. 2- High School Textbooks: Review and Evaluation. v. Screening and Selection of a Suitable Extraction Procedure for Aflatoxins Contamination in Peanuts. Delivered as oral Presentation in: International Symposium on Food Safety, Oct. 2000, Saudi Arabia. vi. Essential Oils Content and Composition in Mentha longifolia and Mentha spicata at three ontogenetic stages. Accepted as oral presentation in: 2nd International Conference on Chemistry and its Applications Dec. 02-12, 2003, Doha, Qatar. vii. Teaching Methodologies and Safety in Chemical Laboratory. Presented in Workshop organized in Ahfad University 2007. ------B. Conferences & Workshops Attended Without Contribution i. IUPAC (International Union of Pure & Applied Chemistry) Symposium on Synthesis of Natural Products, Cambridge 1979, UK ii. International Seminar in Export Quality Development 1983, Khartoum, Sudan.

11 iii. IUPAC (international Union of Pure & Applied Chem.) on Chemistry of Natural Products, 1984, Poznan, Poland. iv, Workshop on High Performance Liquid Chromatography 1987, Addis Ababa, Ethiopia. vi. Breast Cancer Conference, UMST, 2011. ………………………………………………………………………

Supervision of undergraduate Research Projects During the period 2006-2016 more than 50 students.

Supervision of postgraduate Research Projects a. Supervision of M.Sc. Research in partial fulfilment of M.Sc. Degree 23 students b. Supervision of M.Sc. (by Research) 09 students. Titles of the research projects are:

1. Determination of Aflatoxins in Animal Feed in Khartoum State, Sudan.

2. Development of UVSpectrophotometric Method for Simultaneous Estimation o f Ibuprofen and Famotidine in Tablet Dosage Form by Absorbance Correction Method and Absorbance Ratio Method.

3. GC-MS-Estimation and Exposure Levels of Environmental BTEX- Air Pollutants Air Pollutants in the ambient air of Khartoum.

4. Preliminary Steps towards Establishment of a UV-spectrophotometric Method for the Analysis of β-lactam Antibiotics via conversion into ferric hydroximate complex as an index of determination (Amoxicillin Model).

5. Determination of Hippuric acid and Methyl hippuric acid in the Urine as indices of Toluene and Xylenes exposure via HPLC/MS/MS. Accepted for publication in International Journal of Research in Pharmacy and Chemistry.vol 5(1), 10-16. January-March 2015.

6. Estimation of Polycyclic Aromatic Hydrocarbons in the Ambient Air of Khartoum City, Sudan. International Journal for Research in Pharmacy and Chemistry, vol 5(2), 327-333.

7. --Method for the Simultaneous Determination of Amlodipine Besylate and Hyd rochlorothiazide in Bulk and Pharmaceutical Formulation, International Joutnal of Research in Pharmacy and Chemistry,5(4), 516-523.

8. Bacteriological Assessment of Drinking Water in Asmara, Eritrea.

9. Seed Properties and Fatty Acid Composition of Flax Seed Oil. .

12 c. Supervision of Ph. D. Research Projects 2 students. The title of the research projects are:

1. Quality analysis of Asmara city drinking water and human health risk-based assessment and ranking of its hazardous pollutants.

2. A comparison and development of analytical methodologies based on AAS, ICP-MS and XRF for the determination of heavy metals in mining areas (Al- butana area , Nile River state)

Students Supervision of Research Projects: Here are titles of dissertations 1. Estimation of Aflatoxins in Sudanese Groundnuts (M. Sc. Thesis, University of Gezira, Sudan).

2. Extraction of Agar and Alginic Acid from the Red Sea Weeds.

3. Chemical Composition of Cucurbita pepo (Dubba) Seedoil.

4. Analysis and Estimation of Fungal Toxins in Peanuts.

5. Screening of alkaloids in the Eritrean Medicinal Plants.

6. Extraction of essential oils from Eritrean Fragrant Plants.

7. Bioassay studies of Eritrean Medicinal Plants.

8. Synthesis, Purification and analysis of Aspirin.

9. Chromatographic Separation of the Constituents of Cassia Senna.

10. Flavonoids from the Edible Parts of some Plants.

11. Treatments of Emulsions of Petroleum Crude Oil.

12. Quality Parameters Studies of the loacally Manufactured Brands of Praziquantel Drug.

13. Quality Parameters Studies of the locally Manufactured Brands of Ciprofloxacin Drug.

14. Chemical constitution of Acacia seyal Essential Oil.

13 15. Number of Research Projects in Pharmaceutical Analysis in partial fulfilment of M.Sc. Degree (unlimited number) ------

Selected Published Research Papers and Articles

1. Y.M.H. Younis. Pesticides and the Environment, Eritrea Profile, Weekly Newspaper, March 18, 1995.

2. Y.M.H. Younis. The importance of Central Quality Control Laboratory in Eritrea, Eritrea Profile Weekly Newspaper, Oct. 1996.

3. Y.M.H. Younis & Senait Ghirmay. Characteristics and chemical composition of the oil of Cucurbita pepo Seeds Bulletin of the Chemical Society of Ethiopia, 1998, 83-86.

4. Y.M.H. Younis, Senait Ghirmay & Shar Al-Shihry. African Cucurbita pepo: Variability in Seed Properties and Fatty Acid Composition in Seedoil, Phytochemistry, Vol. 54, 2000, 71-75.

5. Y.M.H. Younis. (2000). Alginic Acid, agar contents and biomass of some alga growing in the Southwest coast of the Red Sea, International Journal of Chemistry, Vol. 10/2, 2000, 77-82.

6. Y.M.H. Younis & Shar Al-Shihry. Triacetic acid lactone methyl ether as natural products synthon, Australian Journal of Chemistry, Vol.53, 2000, 589-591.

7. Y.M.H. Younis (2001). Formation and synthetic use of a novel extended enolate of triacetic lactone methyl ether. J. Saudi Chemical Society, vol. 4(2), 291-300.

8. Y.M.H. Younis & Kamal M. Malik (2001). Comparative study of the efficiency of four extraction procedures and HPLC versus TLC estimation of aflatoxins in peanuts and peanut products. J. Saudi Chemical Society, vol. 5 (1), 19-28.

9. Y.M.H. Younis (2001). Demethylation of some arylethers and selective demethylation of some pyrones by the use of iodotri- methylsilane. International J. of Chemistry, vol. 11(2), 75-85.

14 10. Y.M.H. Younis & Kamal M. Malik (2003). Assays on aflatoxins contamination in Sudanese peanuts and peanut products. Kuwait J. of Science & Engineering, 30(1), 79-94.

12. Y.M.H. Younis & Shadia M. Beshir. Carvone-Rich Essential Oils from Mentha longifolia (L.) Huds. subsp. schimperi Brig. And Mentha spicata L. grown in Sudan. Journal of Essential Oil Research, Journal of Essential Oil Research, vol 16, 539-541.

13. Younis M.H. Younis, Shadia M. Beshir, Shar S. Al-shihry, Mahmoud Sirag (2004). Estimation of Essential Oils Contents And Composition from Mentha long folia (L.) Huds. Subsp. Schimperi Brig.and Mentha spicata at three ontogentic stages. Oral presentation in the 2nd International Conference of Chemistry and its Applications, October 2004, Qatar.

14. Younis M.H. Younis and Shar S. Al-Sherry: Text Book in Arabic Language entitled: The Chemistry of Petroleum, Petrochemic als & Polymers 2005.3rd edition published in 2015.

15. Zerabruk Tesfamariam**, Younis M. H. Younis and Suliman S. Elsanousi . (2016). Heavy metal status of sediment and water from Mainefhi and Toker Drinking-water Reservoirs in Asmara, Eritrea (III). American Journal of Research and Communication submitted, Vol 4(6): 76-88. 16. Zerabruk Tesfamariam**, Suliman S. Elsanousi and Younis M. H. Younis (2015). Bacteriological Assessment of Drinking Water in Asmara, Eritrea. European International Journal of Science and Technology, vol 4 (8).143-151

17. Zerabruk Tesfamariam**, Younis M. H. Younis (2016). Assessment of physicochemical parameters and heavy metals in the drinking water of Asmara City, Eritrea (II). American Journal of Research and Communication, August 2016. American Journal of Research Communication, 2016, 4(8): 30-44.

15 Publications during the Period (2009-todate) of Service in University of Medical Sciences and Technology

1. Amin O. Elzupir, Younis M.H. Younis, M. Himmat & A. M. Elhussein (2009). Determination of Aflatoxins in Animal Feed in Khartoum State, Sudan. Journal of Animal and Veterinary Advances 8(5): 1000-1003

2. Khalid M. Algobahi and Younis M.H. Younis (2012). Development of UV-Spectrophotometric Method for Simultaneous Estimation o f Ibuprofen and Famotidine in Tablet Dosage Form by Absorbance Correction Method and Absorbance Ratio Method. International Journal of Research in Pharmacy and Science, July-September Issue, 2012, 2(3), 69- 80. [Best research article in that issue].

3. Dareen A. Salih and Younis M.H. Younis (2013). GC-MS-Estimation and Exposure Levels of Environmental Benzene in the BTEX- Mixture of Air Pollutants. International Journal of Research in Pharmacy and Chemistry, Vol 3 (1), 88-94.

4. Abedul Alla M. O. Tanon and Younis M.H. Younis (2014). Preliminary Steps towards Establishment of a UV-spectrophotometric Method for the Analysis of β-lactam Antibiotics via conversion into ferric hydroximate complex as an index of determination (Amoxicillin Model). International Journal of Research in Pharmacy and Chemistry,4(2),243-253.

5. Nawal Hassan M. Ahmed and Younis M.H. Younis (2015). Determination of Hippuric acid and Methyl hippuric acid in the Urine as indices of Toluene and Xylenes exposure via HPLC/MS/MS. Accepted for publication in International Journal of Research in Pharmacy and Chemistry.vol 5(1), 10-16. January- March 2015.

6. Mohamed M. Osman and Y.M.H. Younis (2015). Estimation of Polycyclic Aromatic Hydrocarbons in the Ambient Air of Khartoum City, Sudan. International Journal for Research in Pharmacy and Chemistry, vol 5(2), 327- 333.

7. Younis M.H. Younis and Babiker H. Al-Rasool*(2015). Validated RP- HPLC Method for the Simultaneous Determination of Amlodipine Besylate and Hydr ochlorothiazide in Bulk and Pharmaceutical Formulation, International Joutnal of Research in Pharmacy and Chemistry,5(4), 516-523.

8. Zerabruk Tesfamariam**, Suliman S. Elsanousi and Younis M. H. Younis (2015). Bacteriological Assessment of Drinking Water in Asmara, Eritrea. European International Journal of Science and Technology, vol 4 (8).143-151

16 9. Nusiba Taha Fazary and Younis Mohammed Younis (2015). Seed Properties and Fatty Acid Composition of Flax Seed Oil. World Journal of Pharmaceutical Sciences, Vol 4 (11), 69-99.

10. Zerabruk Tesfamariam**, Younis M. H. Younis and Suliman S. Elsanousi .(2016). Heavy metal status of sediment and water from Mainefhi and Toker Drinking-water Reservoirs in Asmara, Eritrea (III). American Journal of Research and Communication submitted, Vol 4(6): 76-88.

11. Zerabruk Tesfamariam**, Younis M. H. Younis and Suliman S. Elsanousi and Assessment of physicochemical parameters and heavy metals in the drinking water of Asmara City, Eritrea (II). American Journal of Research and Communication Accepted for publication, expected to be published in August 2016.

……………………………………………………………………… *in collaboration with Azal Pharmaceuticals comp.Sudan **Ph. D. Student from Eritrea

Documented Unpublished Research Work The following research projects have been legally donated to SANDOZ – Pharmaceutical Company, Basil, Switzerland, 1984. The agreement prohibits publication: 1. Extraction, Isolation and Elucidation of Structure of Compounds with Inhibiting Activity on Contractions of the Isolated Guinea Pig Ileum from Ovarian denhardtiana and Hibiscus Micranthus. 2. Isolation of Aglycone of a Triterpenic Saponin from Adisia bromi 3. a. Development of a New Extraction Procedure of Sennosides from Cassia acutifolia. b. Distribution of Sennosides in Cassia acutifolia as Determined by High Performance Liquid Chromatography (HPLC). (The above work has been performed in the Biomedical Centre BMC, Uppsala University, Sweden and in SANDOZ Laboratories in Basil Switzerland in collaboration with Professor Gunner Samulesson). Research Projects in Progress: The general current research fiels interests consist of the following areas of studies a. Chemical constitution of food and feed nutrients. b. Food and feed safety (Qualitative and quantitative analysis of contamination of food and feed with mycotoxins). c. Environmental pollution: (carcinogens in air and drinking water pollution). 1. Fatty Acid Composition & Accumulation of the minor constituents [Phytosterols, tocopherols, glucosinolates carotenoid s] seed oil of Brassica napus.(Manuscript ready to be submitted for publication)

17 2. Accumulation of the minor constituents [Phytosterols, Toco- pherols, gluco sinolates & Caretenoids] in Cucurbita pepo seed oil. (Manuscript ready for publication). 3. Estimation of Essential Oils and Composition from Mentha longifolia (L.) subsp. Schimperi Brig. and Mentha spicata (L.) at three Ontogenetic Stages (Manuscript ready for publication). 4. [Industrial Chemistry-Selected Industries] a textbook in preparation (Younis M.H. Younis & T. Micheal Haile). 5. Effect of Agricultural Practices on the Content and Composition of Essential Oils from Mentha longifolia and Mentha specata.To be submitted for publication very soon. 6. Supervision of the following M.Sc. Degree (by research) Projects in Environmental Pollution: i. Screening of Carcinogenic Volatile Organic Aromatic Hydrocarbons (BTEX) in the Ambient of Khartoum State by GC- Analysis. ii.Monitoring BTEX pollutants and PAHs in oil fields. iii. Screening of Carcinogenic Polycyclic Aromatic Hydrocarbons in Ambient Air by GC-Analysis. iv. HPLC-Determination of Hippuric Acid and Methylhippuric Acid as Indices to Exposure of Benzene and Toluene.

7. Supervision of the following M.Sc. Degree (by courses) research projects: i. Pharmaceutical Quality Control Analysis of four locally manufactured Ciprofloxicine drug samples ii. Extraction and GC-Chemical Composition of the Essential Oil of Acacia seyal Bark. iii. Pharmaceutical and Quality Control Analysis of three Locally Manufactured Praziquantel Drug Samples. iv. Infra-Red Profiles of some Locally Manufactured Drugs. v. The Validity of Head Space GC-Analysis Polluted Drinking Water. vi. Analysis of Drinking Water in Asmara City (Eritrea) to commence September 2013. ………………………………………………………………………..

Proposals Implemented in Different Universities 1. Proposal for Chemistry Curriculum Development, University of Zawia, Libya, 1991. 2. Proposal for Rehabilitation Program of the Chemistry Department, University of Asmara, 1995, Eritrea. It includes: Department Profile, Staff Development Plan, Strengthening Teaching Facilities, Strengthening Research Facilities, Curricul- um Develop ment & Library Development. The plan has been approved and financially supported by SIDA (Swedish International Development Agency) and SAREC (Swedish Agency for Research Cooperation)

18 3. Proposal for Research on the Chemistry of Medicinal Plants of Eritrea, 1996, Eritrea. The project has been sponsored by SAREC. Strategic Plan for Research in Medicinal Plants of Eritrea (A detailed research plan, supported by SAREC & UNISCO). 4. Space Master Plan for the Chemistry Department in the New University Campus. 5. Proposal and Space Master Plan for University Analytical Central Laboratory (An instrumental & chemical analysis laboratory offering analytical service to university, government departments and private sector). 6. Space Master Plan for the Department of Chemistry in the Community College in the town of Mendefera. Requested by the Ministry of Education, Government of Eritrea. 7. Space Master Plan for the Junior School Teachers College in the town of Kern. Requested by the Ministry of Education, Government of Eritrea. 8. Guidelines for setting and grading examinations by G. Ogbazghi & Younis M. H. Younis. 9. Proposal for the Establishment of a University Central Analytical Laboratory. (Providing analytical services to University Colleges, Government & Private Sectors). The laboratory is equipped with chromatography & spectroscopic instruments in addition to the necessary glassware & chemicals. Funds are provided by SIDA. 10. Proposal for the Establishment of Drug Discovery Research Centre in Southern Sudan (utilizing the medicinal plants of the region), submitted to the Ministry of Higher Education, Government of Sudan 2006. (The project has not yet been implemented). 11. Proposal for the Establishment of Institute of Science & Technology in Southern Sudan, submitted to the Ministry of Higher Education, Government of Sudan 2006. (The project has not yet been implemented). 12. Proposal for Curriculum Setting, Review & Development. Submitted to Eritrea Institute of Technology, Maine, Asmara, Eritrea (2004). Submitted during my assignment as Director of Curriculum Review & Development. 13. Proposal for the establishment of the UMST-Pharmaceutical Technology and Pharmaceutical and Chemical Analysis Centre. University of Medical Sciences and Technology. 14. Guidelines and format for writing research proposal. 15. Guidelines and format for writing research thesis. 16. Feasibility Study for the Publication of Journal of Medical Sciences and Technology. ------Referees

1. Prof.Dr. El-Sheikh Ali El-Obaid Secretary General; Sudan Medical Council P.O. Box 800 Khartoum, Sudan E-mail Address [email protected] Second postal address: Prof.Dr. El-Sheikh Ali El-Obaid Head Department of Biotechnology

19 Faculty of Pharmacy, Ahfad University for Women. Om-durman, Sudan. Mobile phone number (+249)9123 650 51

2. Prof. Dr Ghebreberhan Ogbazghi, x-Dean Faculty of Science, x-Vice President Asmara University x-president of Eritrea Institute of Science and Technology. [Currently in sabbatical leave in the University of Botswana up to December 2013]. Current address University of Botswana, South Afrca. E-mail address: [email protected] ------Professor Younis Mohamed Elhassan Younis (09126 431 53) B.Sc (Honours), M.Sc., Khartoum, Sudan. H.Dip., UMIST, Manchester, UK., Ph.D. Cambridge, UK, H.Dip. Uppsala, .Sweden

Selected Published Research Papers and Articles

1. Y.M.H. Younis. Pesticides and the Environment, Eritrea Profile, Weekly Newspaper, March 18, 1995.

2. Y.M.H. Younis. The importance of Central Quality Control Laboratory in Eritrea, Eritrea Profile Weekly Newspaper, Oct. 1996.

3. Y.M.H. Younis & Senait Ghirmay. Characteristics and chemical composition of the oil of Cucurbita pepo Seeds Bulletin of the Chemical Society of Ethiopia, 1998, 83-86.

4. Y.M.H. Younis, Senait Ghirmay & Shar Al-Shihry. African Cucurbita pepo: Variability in Seed Properties and Fatty Acid Composition in Seedoil, Phytochemistry, Vol. 54, 2000, 71-75.

5. Y.M.H. Younis. (2000). Alginic Acid, agar contents and biomass of some alga growing in the Southwest coast of the Red Sea, International Journal of Chemistry, Vol. 10/2, 2000, 77-82.

6. Y.M.H. Younis & Shar Al-Shihry. Triacetic acid lactone methyl ether as natural products synthon, Australian Journal of Chemistry, Vol.53, 2000, 589-591.

20 7. Y.M.H. Younis (2001). Formation and synthetic use of a novel extended enolate of triacetic lactone methyl ether. J. Saudi Chemical Society, vol. 4(2), 291-300.

8. Y.M.H. Younis & Kamal M. Malik (2001). Comparative study of the efficiency of four extraction procedures and HPLC versus TLC estimation of aflatoxins in peanuts and peanut products. J. Saudi Chemical Society, vol. 5 (1), 19-28.

9. Y.M.H. Younis (2001). Demethylation of some arylethers and selective demethylation of some pyrones by the use of iodotri- methylsilane. International J. of Chemistry, vol. 11(2), 75-85.

10. Y.M.H. Younis & Kamal M. Malik (2003). Assays on aflatoxins contamination in Sudanese peanuts and peanut products. Kuwait J. of Science and Engineering, 30(1), 79-94.

12. Y.M.H. Younis & Shadia M. Beshir. Carvone-Rich Essential Oils from Mentha longifolia (L.) Huds. subsp. schimperi Brig. And Menth a spicata L. grown in Sudan., Journal of Essential Oil Research, vol 16, 539- 541.

13. Younis M.H. Younis, Shadia M. Beshir, Shar S. Al-shihry, Mahmoud Sirag (2004). Estimation of Essential Oils Content and Composition from Mentha long folia (L.) Huds. Subsp. Schimperi Brig.and Me ntha spicata at three ontogentic stages. Oral presentation in the 2n d International Conference of Chemistry and its Applications, October 2004, Qatar.

14. Younis M.H. Youns and Shar S. Al-Sherry: Text Book entitled: The Chemistry of Petroleum, Petrochemicals & Polymers 2005. King Faisal University Press, Saudi Arabia

15. Amin O. Elzupir, Younis M.H. Younis, M. Himmat and A. M. Elhussein (2009). Determination of Aflatoxins in Animal Feed in Khartoum State, Sudan. Journal of Animal and Veterinary Advances (Accepted, to be published April 2009).

16. Khalid M. Algobahi and Younis M.H. Younis (2012). Development of UV- Spectrophotometric Method for Simultaneous Estimation of Ibuprofen and Famotidine in Tablet

21 Dosage Form by Absornce Correction Method and Absorbance Ratio Method. Accepted for Publication in the International Journal in Pharmacy and Science, July 26, 2012. 2(3), 69-80 (best research paper)

17. Mohamed M. Osman and Y.M.H. Younis (2012). Estimation of Polycyclic Aromatic Hydrocarbons in the Ambient Air of Khartoum City, Sudan. Accepted for Publication. Australian Journal of Chemistry

18. Dareen A. Salih and Younis M.H. Younis (2013). GC-MS Estimation and Exposure levels of Environmental Benzene in the BTEX mixture of Air Pollutants. International Journal of Research in Pharmacy and Chemistry, vol3, 87-94.

19. Abedul Alla O. Tanon and Younis M.H. Younis (2014). Preliminary steps towards establishment of a UV- spectrophotometric method for the analysis and estimation of β- lactam antibiotics via conversion into ferric hydroximate complex as index of determination (Amoxicillin Model).International Jouirnal of Research in Pharmacy and Chemistry, 4(2), 243-253.

20. Nawal Hassan M. Ahmed and Younis M.H. Younis (2015). Determination of Hippuric acid and Methyl hippuric acid in the Urine as indices of Toluene and Xylenes exposure via HPLC/MS/MS. Accepted for publication in International Journal of Research in Pharmacy and Chemistry.vol 5(1), 10-16. January-March 2015.

21. Mohammed.M. Osman, Younis M.H. Younis (2015). Estimation of Polycyclic Aromatic Hydrocarbons (PAHs) Pollutants in the Ambient Air of Khartoum City, Sudan (Part III). International Journal of Research in Pharmacy and Chemistry.vol 5(2), 327-333.

22. Younis M.H. Younis and Babiker H. Al-Rasool (2015). Validated RP-HPLC Method for the Simultaneous Determination of Amlodipine Besylate and Hydrochlorothiazide in Bulk and Pharmaceutical Formulation, International Joutnal of Research in Pharmacy and Chemistry,5(4), 516-523.

22 23. Zerabruk Tesfamariam**, Suliman S. Elsanousi and Younis M. H. Younis (2015). Bacteriological Assessment of Drinking Water in Asmara, Eritrea. European International Journal of Science and Technology, vol 4 (8).143-151

24. Nusiba Taha Fazary and Younis Mohammed Younis (2015). Seed Properties and Fatty Acid Composition of Flax Seed Oil. World Journal of Pharmaceutical Sciences, Vol 4 (11), 69-99.

25.Zerabruk Tesfamariam**, Younis M. H.Younis and Suliman S. Elsanousi (2016) Assessment of physicochemical parameters and heavy metals in the drinking water of Asmara City, Eritrea (II). American Journal of Research and Communication, vol 4(8): 30- 44.

26.Zerabruk Tesfamariam**, Younis M. H. Younis. (2016). Heavy metal status of sediment and water from Mainefhi and Toker Drinking- water Reservoirs in Asmara, Eritrea (III). American Journal of Research and Communication Vol 4(6): 76-88.

27.Younis M.H. Younis1* and Zerabruk Tesfamariam2 (2017). Geochemical analysis of sediment samples from Asmara drinking water reservoirs for estimation of contamination by heavy metals (IV), Accepted for publication in American Journal of Research and Communication Vol 4(6): 76-88.

28.Sally Mohamed Ahmed, Abdalla Ahmed Elbeshir & Younis Mohamed Elhassan (2016). Application of 2-chloro-7-nitrobenzo-2- oxa-1,3-diazol(NBD-Cl) for spectrophotometric determination of Finasteride in pharmaceutical formulation. International Journal of Advanced Research in Chemical Science (IJARCS), volume 3, issue 12,

29. Publication of three Laboratory Manuals, Asmara University:

i. Laboratory Techniques in Organic Chemistry Manual

23 ii. Qualitative Organic Chemical Analysis iii. Selected Reactions in Organic Synthesis

30.Younis Mohamed Elhassan and Shar Saad Elshihry: Petroleum Chemistry and Organic Polymers; Textbook, A University, King Faisal University published 2005, and reprinted 2008 and 2016.

31.

Teaching Experiences [List of Universities] i. University of Khartoum< Faculty of Science. (Sudan). ii. University of Khartoum Faculty of Education. (Sudan). iii. Om-Durman Islamic University. (Sudan). iv. University of Gezira, Faculty of Science and Technology. (Sudan). v. University of Gezira, Faculty of Medicine (Sudan). vi. University of Sebha, (Libya) vii. University of Zawia (Libya). viii. University of Asmara (Erirea) ix. King Faisal University, Faculty of Science (Saudi Arabia). x. King Faisal University, Faculty of Education (Saudi Arabia) xi. University of Asmara, Faculty of Pharmacy.(Eritrea) xii. Institute of Science and Technology (Eritrea) xiii. Ahfad University for Women, Faculty of Pharmacy0 (Sudan).

24 xiv. University of Khartoum (Sudan) xv. Faculty of Pharmacy, Nile College (Sudan). xvi. International University of Africa (Sudan). xvii. University of Medical Sciences and Technology, Faculty of Pharmacy (Sudan

25

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