Genetic Processes - Unit in Review

SBI3U Genetic Processes - Unit in Review

Review material in the following sections of the textbook and focus on the specific topics listed below: -4.1, 4.2, 4.3, 4.4, 4.5 -5.1, 5.2, 5.3, 5.5, 5.7 -6.1, 6.2, 6.3, 6.4, 6.5 Key terms from the textbook that you need to know are indicated in bold face.

Cell Division - Mitosis (review), Cloning: (4.1, 4.2) -genetics terms: genetics, deoxyribonucleic acid (DNA), gene, locus -compare and contrast asexual & sexual reproduction -main events during the phases of mitosis (movement of chromosomes, cell division) -interphase, chromatin, sister chromatids, cytokinesis

Meiosis, Structure of DNA, Chromosomes: (4.3, 6.1) -main events during the phases of meiosis (movement of chromosomes, cell division) -homologous chromosomes, tetrad, synapsis, crossing over -gametogenesis, spermatogenesis, oogenesis -differences between mitosis & meiosis -basic structure of DNA -nucleotide, complementary base pairing

Genetic Disorders, Karyotypes, etc.: (4.4, 5.5, 6.2) -analysis of karyotypes -sex chromosomes, autosomes -examples of chromosomal abnormalities caused by non-disjunction of chromosomes during meiosis (monosomy, trisomy) such as Down syndrome -types of mutations (point mutation vs chromosome mutation) -patterns of inheritance & characteristics of genetic disorders caused by genetic mutations: -cystic fibrosis -some forms of breast cancer -phenylketonuria -sickle-cell anemia -lactose-intolerance & tolerance -genetic screening (e.g., Ontario's Newborn Screening Program)

Patterns of Inheritance: (5.1, 5.2, 5.3, 5.7) -Terms: allele, dominant allele, recessive allele, homozygous, heterozygous, genotype, phenotype -results of Mendel's experiments & Mendelian laws of inheritance -true-breeding, monohybrid cross, P generation, F1 generation, F2 generation -law of segregation -law of independent assortment -test cross -predicting & interpreting data from monohybrid & dihybrid crosses involving complete dominance, incomplete dominance, codominance, and sex-linked traits -using the Punnett square method to solve basic genetic problems -interpreting information in pedigree charts

Connections to Technology, Society, and the Environment: (4.2, 4.4, 6.2, 6.3, 6.4, 6.5) -reproductive technologies (examples & applications to increasing genetic diversity of species) -techniques for cloning plants, animals -genetically-modified organisms (GMOs) -in vitro fertilization -artificial insemination -social and ethical implications of genetics & genomics research -genetic screening -gene therapy -reproductive technologies -recent contributions to techniques & technologies -microarray technology -Human Genome Project (HGP) -coding DNA vs. non-coding DNA -functional genomics -DNA fingerprinting -recombinant DNA -genetic engineering -gene therapy

Evaluation: Date: Categories: KU TI A C Genetics Problem Set √ Unit Test √ √ √ √ Assignment √ √