Research on a Genetic Engineering and Gene Therapy

Name ______Topic ______

You will research a genetic engineering or gene therapy topic and convert it into an informational brochure. The following criteria must be met to earn at least a “B”: 1. Your topic idea MUST BE APPROVED by the teacher before starting. A list of approved topics is available from the teacher. No two students in the same class period can do the same topic. 2. A full page of notes (~20 facts) must be either printed out or hand-written. This does not include drawings. From this, you will build your brochure. Write down the source(s) of your information. Citing in MLA or APA earns more points. 3. The finished brochure must be typed on unlined, 8.5 x 11” paper. Paper orientation is to be ‘landscape’, and the pamphlet of a trifold design. This will result in six panels upon which to place information. When you print it out, it must be properly created in a ‘front and back’ fashion (not two pages stuck together). 4. Your choice of fonts, graphics, and other art should be easily read by your teacher. Items that are too small or too ‘gaudy’ will simply be marked incorrect 5. Do not just cut and paste information, especially if you cannot explain its meaning. You are expected to read and edit, then type the information onto the panels 6. Your brochure is made up of six panels. They should contain the following information. See the diagram to ensure proper placement of your research information a. TITLE PAGE (front of brochure) includes  Topic (type of genetic engineering or gene therapy)  Graphic related to topic b. FIRST INSIDE FLAP should have …  introduction; reason for selecting topic  general definitions of words used in brochure that others might not know c. INSIDE THREE PANELS will contain  target (regular body cells? specific areas of body? cure disease? better food source?)  method or technique (e.g. for getting new genes into body cells; viral vector? etc)  history of discovery, experimentation, major developments  effectiveness; benefits to humankind  problems (hazards? side effects? ethical considerations? etc) d. BACK PANEL will contain  bibliography information  your name, class period, and due date 7. Each panel should be filled with information and graphics. Do not have a lot of empty white space. Vary your fonts and graphic placements. These are the things that increase your score above a “C”. Creativity, imagination, humor, uniqueness…. these all push you above the norm.

LOOK CAREFULLY at the rubric on the back. Your teacher will use it to assess your project.

NO PROJECTS WILL BE ACCEPTED PAST THE DEADLINE. This project counts as much as a test grade. Do not wait until the last day to complete and print out your project. If you are absent the day projects are due, it is expected that you will have someone bring your completed assignment to the teacher at school. Remember to staple your notes to this sheet.

Weakly Meets displayed minimum Exceeded Insufficient (includes Teacher Criteria & Grading Rubric expectations required Evidence ‘sloppy’ work comments with few elements or numerous errors mistakes) Points possible 0 1 2 3 N/A Full sheet of notes on topic indicates thorough research. Notes are referenced (cited) as to source. Title page has topic name and ‘teaser’ phrase (do not put name on title page; goes on back) Introduction (first inside flap) outline basic topic idea, purpose, vocabulary, etc Inside left-hand panel describe history of discovery, including dates, places, and researchers Inside middle panel describe technique used, equipment, particular methodology Inside right-hand panel has information on effectiveness, benefits, problems, etc. Back panel contains bibliographic information and student name, class, & due date Graphic is present on each of the six panels of brochure to add interest and help explain concepts Project meets guidelines for size, appearance (textual, graphic, etc), printing, etc.

Conversion table Points earne 27 26 25 24 23 22 21 20 19 18 17 16 15 14 13 12 10 9 d Grade 100 99 98 96 94 92 90 89 87 85 84 82 80 78 76 74 72 70 Poi nts 8 7 6 5 4 3 2 1 0 ear ned Gra 60 50 40 30 20 15 10 5 0 de FINAL GRADE: ______(counts as a test grade  SIDE ONE SIDE TWO FIRST BACK PANEL TITLE PAGE LEFT MIDDLE RIGHT INSIDE FLAP (first outside INNER INNER INNER (flap under title Bibliography flap) PANEL PANEL PANEL page) (sources used) historical or method or effectiveness Introduction Name of topic background technique Reason for Name information used benefits selecting topic Class period (people, Difficult or Date places, dates, problems unique words what (graphic) and definitions happened) (graphic) used in (graphic) brochure (graphic) (graphic) (graphic)

Remember: you must print this out front and back. This means print side one, take it out and orient it properly in the paper tray, and print side two. If you ask for assistance from the Media Specialists, make sure they have the time to spend on this. TOPICS FOR BROCHURE PROJECT

1. genetic engineering a. amniocentesis b. bioballistics c. bioinformatics d. chorionic villi sampling e. DNA fingerprinting f. gene cloning g. genetic counseling h. genetic screening i. microinjection j. recombinant DNA k. transgenic animals l. transgenic bacteria m. transgenic plants 2. gene therapy a. albinism b. Alzheimer’s disease c. cancer (give particular type of cancer) d. cystic fibrosis e. diabetes mellitus f. Down’s syndrome g. Duchene muscular cystrophy h. fragile X chromosome i. Galactosemia j. Garrod’s alkaptonuria k. hair loss l. hemophilia m. HIV n. Huntington’s disease o. Klinefelter syndrome p. Parkinson’s disease q. Phenylketonuria (PKU) r. sickle-cell disease s. Tay Sachs Disease t. tuberculosis u. Turner syndrome type of genetic mutation (insertion, deletion, tandem repeat, etc)