Draft 1/27/10 Georgetown Summer Medical Institute Human Physiology, 2014

Course Director Jennifer L. Whitney, PhD 6 Weeks-- June 23- August 1, 2014

Topics covered: Fluid Homeostasis Neurophysiology Endocrinology Respiratory Physiology Cardiovascular Physiology Renal Physiology Acid/Base Physiology Gastrointestinal Physiology

Teaching modalities: Didactic lectures Problem-Solving Workshops Case-Based Studies Homework Problems

Evaluation: 6 Multiple-Choice Exams (~200 questions) 6 Homework Assignments

Passing grades will be determined by comparison with the medical class.

Textbook: Netter’s Essential Physiology by Mulroney & Myers or Costanzo’s Physiology (will be provided)

Georgetown University School of Medicine Excellence and Innovation in Education and Research Draft 1/27/10 Georgetown Summer Medical Institute Human Physiology, 2014

DATE 6/23 6/24 6/25 6/26 6/27 Day Monday Tuesday Wednesday Thursday Friday 9:00-10:00 Orientation

10:00-11:00 Introduction Properties of Axonal Muscle Cardiac & Cell Function Physiology Electro- Fluid Membranes physiology Compartments

11:00-12:00 Osmosis Introduction The Autonomic EKG To Synapse & & Neuro- Reflex Arrythmias physiology Pathways

12-1pm Lunch 1:00-2:00 Problem Problem Case Problem Solving Solving Studies Solving Workshop #1 Workshop #2 #1 Workshop (Osmosis) (Nernst Eq) (Neuro) #3 (EKG & Arrythmias)

2:00-3:00 REVIEW (Fluids and Neurophys)

Lecturer: Dr Mulroney Dr Vicini/ Dr Vicini Dr Vicini Dr Vicini/ Dr Whitney

Georgetown University School of Medicine Excellence and Innovation in Education and Research Draft 1/27/10

DATE 6/30 7/1 7/2 7/3 7/4 Day Monday Tuesday Wednesday Thursday Friday 9:00-10:00 EXAM #1 (Fluids/NP/ EKG/ arrythmias) 2 hours

10:00- Hypoxia, 11:00 Mechanics Ventilation- Hypoxemia, of Breathing Perfusion and Acid Base Relationship Balance

11:00- Pulmonary 12:00 Structure and Transport of Function Function of the Oxygen and Control of Tests and Respiratory CO2 Breathing, Clinical System Integrative Applications Functions

12-1pm Lunch 1:00-2:00 Ventilation Case Studies REVIEW Lung Volumes of Gas #3 (Respiratory and Capacities Exchange (Respiratory)

2:00-3:00

Lecturer: Dr Natarajan Dr Natarajan Dr Natarajan Dr Natarajan

Georgetown University School of Medicine Excellence and Innovation in Education and Research Draft 1/27/10 DATE 7/7 7/8 7/9 7/10 7/11 Day Monday Tuesday Wednesday Thursday Friday 9:00- 10:00 EXAM #2 (Respiratory) 90 MIN

10:00- 11:00 Regulation of Local Pulmonary Structure (Break 10:30- Cardiac Output Control of and & 11:00) I Blood Fetal Function of Flow Circulations the Kidney

11:00- 12:00 Overview of Regulation of Neuro- Case Studies Glomerular Cardiovascula Cardiac Output humoral #2 Filtration r II Regulation (C-V) Physiology of Blood (Circulation Pressure and Pressures)

12-1pm Lunch 1:00-2:00 Coronary Biophysics of Micro- and Integrative the circulation Cerebral Review of Circulation Circulation C-V Function) s

2:00-3:00 Cardiac Cycle Problem Mini- Solving Review Workshop #4 (Hemo- dynamics)

Lecturer: Dr Myers Dr Myers Dr Myers Dr Myers Dr Myers

Georgetown University School of Medicine Excellence and Innovation in Education and Research Draft 1/27/10

DATE 7/14 7/15 7/16 7/17 7/18 Day Monday Tuesday Wednesday Thursday Friday 9:00- 10:30 EXAM #3 (Endo) 90 MIN

10:00- 11:00 (Break 10:30- Tubular Regulation of Case 11:00) Transport Urine Acid/Base Studies Concentration Balance #5 (Renal 11:00- 12:00 Regulation of Regulation Problem Kidney Sodium of Solving Structure and Reabsorption Extracellular Workshop Function Fluid & #7 Osmolarity (Clinical Acid-Base Disorders)

12-1pm Lunch 1:00-2:00 Problem Case Glomerular Solving PSW #6 Studies Filtration Rate Workshop #6 #5 Assessment of (Acid/Base) (Clearance) Tubular Cardio) Function

2:00-3:00

Lecturer: Dr Whitney Dr Whitney Dr Whitney Dr Whitney Dr Whitney

Georgetown University School of Medicine Excellence and Innovation in Education and Research Draft 1/27/10 DATE 7/21 7/22 7/23 7/24 7/25 Day Monday Tuesday Wednesday Thursday Friday 9:00-10:00 EXAM #4 (Cardio) 90 MIN

10:00- 11:00 Endocrinology Endocrinology Endocrinolog Overview of (Break 10:30- of the Ovary of the Thyroid y of the GI system 11:00) and Female Gland Calcium Reproductive Regulation Tract

11:00- 12:00 Hypothalamic Endocrinology Endocrinology The Adrenal GI Motility / of the Testis of the Cortex and Pituitary Axis and Male Pancreas the I Reproductive Endocrine Tract Physiology of Stress & Immunity

12-1pm Lunch 1:00-2:00 Hypothalamic Endocrinology Case / of posterior Studies #4 Pituitary Axis pituitary, (Endo) II and Growth oxytocin, and vasopressin

2:00-3:00

Lecturer: Dr Lumpkin Dr Lumpkin/Sherman Dr Lumpkin Dr Lumpkin Dr Mulroney

Georgetown University School of Medicine Excellence and Innovation in Education and Research Draft 1/27/10 DATE 7/28 7/29 7/30 7/31 8/1 Day Monday Tuesday Wednesday Thursday Friday 9:00-10:00 EXAM #5 (Renal) 90 MIN

10:00-11:00 (Break 10:30- Hepatobiliary Case EXAM 11 AM) Function Studies #6 #7 (GI) (GI) (90 MIN) 11:00-12:00 Gastrointestina l Secretions I

12-1pm Lunch 1:00-2:00 Gastrointestina Digestion REVIEW l & (GI) Secretions Absorption II I

2:00-3:00 Digestion & Absorption II

Lecturer: Dr Mulroney Dr Mulroney Dr Mulroney Dr Whitney

Georgetown University School of Medicine Excellence and Innovation in Education and Research