Supporting information

Aberrant axonal arborization of PDF neurons induced by Aβ42-mediated

JNK activation underlies sleep disturbance in an Alzheimer’s model

Qian Song, Ge Feng, Zehua Huang, Xiaoman Chen, Zhaohuan Chen and Yong Ping

Supplemental figure 1

Figure s1. Aβ42 expression doesn’t change rhythm strength (relative FFT values) in young (< 15 days old) flies. (a) Activity records of representative Aβ40 and Aβ42 flies for 5 d in LD and following 5 d in constant darkness (DD). (b) There is no difference in the strength of rest-activity rhythms between Aβ40 and Aβ42 flies. Flies were considered arrhythmic with FFT values below 0.04. Flies were considered weakly rhythmic with FFT values between 0.04 and 0.08, while flies with the values above 0.08 were considered strongly rhythmic.

Supplemental figure 2