The Purpose of TAG Mail Is to Assist TAG Members Identify and Share Relevant Information

TAG Mail 16 November 2016

The purpose of TAG Mail is to assist TAG members identify and share relevant information for their professional practice. Members are encouraged to routinely forward TAG Mail to others who they believe would benefit from this information such as colleagues in the same hospital department if they are not already receiving TAG Mail.

TAG ACTIVITIES **Medicines Management 2016 Sasha Bennett, Margaret Jordan and Lisa Shaheen will be attending the SHPA National Conference in Perth this week. NSW TAG is presenting an oral paper entitled ‘Wising up: Revitalising drug usage evaluation activity in NSW and ACT hospitals’ and a poster entitled ‘Eyes wide open: Making wise choices for medicines used in eye surgery.’

** NSW TAG Life Saving Drugs Register: Antivenom Stocks 2016 Survey - Thank you to those who have already completed the antivenom survey for their facilities. For facilities that have not yet responded please do so at their earliest convenience using the following link https://www.surveymonkey.com/r/antivenom2016 These registers are used by NSW hospitals, hospitals of other jurisdictions, retrieval services and Poisons Information Centres across Australia to provide 24-hour assistance in location of antidote and antivenom stocks. As such, when NSW TAG has not received stock information from a hospital, the hospital will be listed with a ‘NO DETAILS PROVIDED’ notation. Hospitals which do not stock antidotes or antivenoms will also be identified.

TAG WEBSITE **CIAP - CIAP has disabled the following forms on the NSW TAG website: http://www.ciap.health.nsw.gov.au/nswtag/about/contact.html http://www.ciap.health.nsw.gov.au/nswtag/about/how-to-apply.html Please contact NSW TAG via email [email protected] or by calling 02 8382 2852.

CONSULTATIONS **TGA - Consultation: diclofenac, flurbiprofen, ibuprofen, ketoprofen, mefenamic acid and naproxen for oral use – proposed additional advisory statement for medicines. Closes 22 November 2016 http://www.tga.gov.au/consultation/consultation-diclofenac-flurbiprofen-ibuprofen-ketoprofen- mefenamic-acid-and-naproxen-oral-use-proposed-additional-advisory-statement-medicines - Consultation: paracetamol and ibuprofen – advisory statements for medicines. Closes 22 November 2016 http://www.tga.gov.au/consultation/consultation-paracetamol-and-ibuprofen-advisory-statements- medicines - Consultation: Orphan drug program- 2015 consultation outcomes and 2016 orphan drug program proposal. Closes Friday 25 November 2016. http://www.tga.gov.au/consultation/consultation-orphan-drug-program - Consultation: Software as a Medical Device (SaMD) Clinical evaluation. Closes 2 December 2016 http://www.tga.gov.au/consultation/consultation-software-medical-device-samd-clinical-evaluation

REPORTS AND PUBLICATIONS – AUSTRALIA **AIHW - The use of lung function testing for the diagnosis and management of chronic airways disease http://www.aihw.gov.au/publication-detail/?id=60129557382

**ACSQHC -Vital Signs 2016: The State and Quality in Australian Health Care https://www.safetyandquality.gov.au/publications/vital-signs-2016-the-state-of-safety-and-quality- in-australian-health-care/ **Department of Health - National Antimicrobial Resistance Strategy 2015–2019 http://www.health.gov.au/internet/main/publishing.nsf/Content/ohp-amr.htm

**NPS MedicineWise - Antibiotic resistance in Australia: here and now http://www.nps.org.au/publications/health-professional/health-news-evidence/2016/antibiotic- resistance-in-australia-here-and-now - Antibiotic Awareness Week 2016: tackling a global health problem http://www.nps.org.au/media-centre/media-releases/repository/antibiotic-awareness-week2016- tackling-a-global-health-problem

**TGA - Updating medicine ingredient names - Amidotrizoate meglumine It was previously advised that meglumine diatrizoate would change to diatrizoate meglumine to align with how meglumine salts are displayed. This name will now change to amidotrizoate meglumine to ensure consistent naming of diatrizoate derivatives in Australia. https://www.tga.gov.au/updating-medicine-ingredient-names-list-affected-ingredients - Medicines and vaccines post market vigilance- statistics for 2015 http://www.tga.gov.au/medicines-and-vaccines-post-market-vigilance-statistics-2015 - Prescription medicines: Saxagliptin (Onglyza TM) extension of indications http://www.tga.gov.au/prescription-medicines-new-or-extended-uses-registered-medicines

REPORTS AND PUBLICATIONS – INTERNATIONAL **CADTH - Plerixafor for Patients Failing Stem Cell Mobilization: A Review of the Clinical and Cost-Effectiveness and Guidelines https://www.cadth.ca/plerixafor-patients-failing-stem-cell-mobilization-review-clinical-and-cost- effectiveness-and

** Drugs and Therapeutics Bulletin - Prescribing information sources for healthcare professionals http://dtb.bmj.com/content/54/11/129.short?g=w_dtb_currentissue_tab

**NICE - Minimal change disease and focal segmental glomerulosclerosis in adults: rituximab https://www.nice.org.uk/advice/es1/chapter/Key-points-from-the-evidence - Diabetes (type 1 and type 2) in children and young people: diagnosis and management https://www.nice.org.uk/guidance/ng18 - Hypertension in adults: diagnosis and management https://www.nice.org.uk/guidance/cg127

MEDICATION SAFETY **NSW Health - Safety Notice: Aciclovir intravenous infusion preparations – Disruption to supply http://www.health.nsw.gov.au/sabs/Documents/2016-sn-012.pdf

**NHS - Patient Safety Alert: Risk of death and severe harm from error with injectable phenytoin https://www.cas.dh.gov.uk/ViewandAcknowledgment/ViewAlert.aspx?AlertID=102553

OTHER NEWS **Aspen Australia has recently relaunched lorazepam (AtivanTM) 1mg tablets in blister packaging in response to NSW Health concerns with the bottle.

**University of Sydney Researchers at the University of Sydney invite all medical, dental and veterinary practitioners and specialists across Australia to participate in an online 15-20 minute survey that seeks to understand attitudes towards antibiotic use and antibiotic resistance, and explore education and resource needs. The survey findings will assist national policy-makers in developing and enhancing policy and education interventions regarding antibiotic use and resistance in Australia. Survey link: https://www.surveymonkey.com/r/researchabq

PAPERS OF INTEREST **Age and Ageing - Health professional perspectives on the management of multimorbidity and polypharmacy for older patients in Australia http://ageing.oxfordjournals.org/content/early/2016/11/09/ageing.afw200.abstract?papetoc

**Australian Prescriber (new drugs) - Mepolizumab for asthma https://www.nps.org.au/australian-prescriber/articles/mepolizumab? utm_medium=email&utm_source=16-11-16&utm_campaign=aus-prescriber - Olaparib for ovarian cancer https://www.nps.org.au/australian-prescriber/articles/olaparib? utm_medium=email&utm_source=16-11-16&utm_campaign=aus-prescriber - Talimogene laherparepvec for melanoma https://www.nps.org.au/australian-prescriber/articles/talimogene-laherparepvec? utm_medium=email&utm_source=16-11-16&utm_campaign=aus-prescriber

**British Journal of Clinical Pharmacology - Clinical trials for authorised biosimilars in the European Union: a systematic review http://onlinelibrary.wiley.com/doi/10.1111/bcp.13076/abstract - A multifaceted intervention to reduce drug-related complications in surgical patients http://onlinelibrary.wiley.com/doi/10.1111/bcp.13141/abstract

**Circulation - The Cost-Effectiveness of Antibiotic Prophylaxis for Patients at Risk of Infective Endocarditis http://circ.ahajournals.org/content/early/2016/11/08/CIRCULATIONAHA.116.022047

**Cochrane Library

-Inhaled corticosteroids with combination inhaled long-acting beta2-agonists and long-acting muscarinic antagonists for chronic obstructive pulmonary disease http://www.cochrane.org/CD011600/AIRWAYS_stable-copd-should-inhaled-corticosteroids-be-used- combination-long-acting-beta2-agonistlong-acting -Valacyclovir compared with acyclovir for the treatment of herpes zoster ophthalmicus in people with an otherwise normal immune system http://www.cochrane.org/CD011503/EYES_valacyclovir-compared-acyclovir-treatment-herpes- zoster-ophthalmicus-people-otherwise-normal-immune -Vitamin D supplementation for preventing infections in children under five http://www.cochrane.org/CD008824/INFECTN_vitamin-d-supplementation-preventing-infections- children-under-five

**Internal Medicine Journal - Assessing understanding: Patients prescribed natalizumab for multiple sclerosis individual risk and symptoms of progressive multifocal leukoencephalopathy http://onlinelibrary.wiley.com/doi/10.1111/imj.13318/full

** JAMA - Statins for Prevention of Cardiovascular Disease in Adults, Evidence Report and Systematic Review for the US Preventive Services Task Force http://jamanetwork.com/journals/jama/fullarticle/2584057 -Statin Use for the Primary Prevention of Cardiovascular Disease in Adults, US Preventative Services Task Force Recommendation Statement http://jamanetwork.com/journals/jama/fullarticle/2584058

**JAMA Cardiology -Association Between Intensity of Statin Therapy and Mortality in Patients With Atherosclerotic Cardiovascular Disease http://jamanetwork.com/journals/jamacardiology/fullarticle/2580531 - Reduced Risk of Hyperkalemia During Treatment of Heart Failure With Mineralocorticoid Receptor Antagonists by Use of Sacubitril/Valsartan Compared With Enalapril, A Secondary Analysis of the PARADIGM-HF Trial http://jamanetwork.com/journals/jamacardiology/article-abstract/2583456

**NEJM -Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis http://www.nejm.org/doi/full/10.1056/NEJMoa1611593 -Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck http://www.nejm.org/doi/full/10.1056/NEJMoa1602252 -Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease http://www.nejm.org/doi/full/10.1056/NEJMoa1611688 -Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer http://www.nejm.org/doi/full/10.1056/NEJMoa1606774 -Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy http://www.nejm.org/doi/full/10.1056/NEJMoa1611299 -Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes http://www.nejm.org/doi/full/10.1056/NEJMoa1607141

**Pediatrics -Infusion Medication Error Reduction by Two-Person Verification: A Quality Improvement Initiative http://pediatrics.aappublications.org/content/early/2016/11/07/peds.2015-4413

UPCOMING EVENTS (new additions in bold) **Australian Institute of Health Innovation - Clinical work patterns, safety and health information technology Tuesday 15th November 2016 Time: 12pm - 1pm Venue: Seminar Room, Level 1, 75 Talavera Road, Macquarie University http://aihi.mq.edu.au/event/clinical-work-patterns-safety-and-health-information-technology - Making Care Safer through EHRs Date: Monday 5th December 2016 Time: 12pm - 1pm Venue: Seminar room, Level 1, 75 Talavera Road, Macquarie University http://aihi.mq.edu.au/event/making-care-safer-through-ehrs -Resilient leadership: Exploring the most appropriate leadership style for resilient organizations within the health care sector Thursday 8th December, 2016 Time: 12pm – 1pm Location: Seminar room, Level 1, 75 Talavera Road, Macquarie University http://aihi.mq.edu.au/event/resilient-leadership-exploring-most-appropriate-leadership-style- resilient-organizations - Making good quality care habitual: An exploration of the concept habit in relation to healthcare professional behaviour Thursday 15th December, 2016 Time: 12pm – 1pm Location: Seminar room, Level 1, 75 Talavera Road, Macquarie University http://aihi.mq.edu.au/event/making-good-quality-care-habitual-exploration-concept-habit- relation-healthcare-professional

**4th World Congress on Integrated Care “Investing in our Future: Improving the Health of People and Communities (WCIC4)” 23-25 November 2016, Wellington New Zealand http://integratedcarefoundation.org/events/wcic4-4th-world-congress-on-integrated-care- wellington-new-zealand

**ASCEPT-MPGPCR 2016 Meeting, 27-30 November 2016, Melbourne Convention Centre Abstracts close: 26 September 2016 http://www.asceptasm.com

**Agency for Clinical Innovation Lunch, Learn and Launch: Social Determinants of Health 30 November 2016 11:45am – 2pm ACI Level 7, Sage Building, 67 Albert St Chatswood https://www.aci.health.nsw.gov.au/__data/assets/pdf_file/0004/339637/SDoH_Event_program.p df

**Best Practice in Chronic Pain Medication Management Day Conference Friday 2nd December Alfred Medical Research and Education Precinct Lecture Theatre, 75 Commercial Road, Melbourne Register Online (registration closes on Thursday 24th November 2016) https://www.eventbrite.co.uk/

**ISMP Medication Safety Intensive, 2-3 December 2016, Las Vegas http://www.ismp.org/educational/MSI/

** APSA 2016 Annual Conference, 2-5 December 2016, University of Sydney https://expertevents.eventsair.com/QuickEventWebsitePortal/apsa2016/website

**The 16th APCCMI (Asia Pacific Congress of Clinical Microbiology & Infection) 30 November - 3 December, 2016, Melbourne. For more information www.apccmi2016.org

** Institute of Health Innovation, Macquarie University Centre for Health Systems and Safety Research, Australian ‘Delivering safer and better care for children in hospital’ symposium, 6 December 2016, The Children’s Hospital at Westmead, NSW http://aihi.mq.edu.au/event/symposium-delivering-safer-and-better-care-children-hospital

**2nd Digital Hospital of the Future, ANZ 2016 ‘Improving Patient Care Delivery and Monitoring with Digital Technology Innovations and Transformation’ 7th-9th December 2016, InterContinental Sydney Australia http://claridenglobal.com/conference/digitalhospital2016/?utm_campaign=L6285_Digital %20Hospital_AU_EDM%202_Buy&utm_medium=email&utm_source=Eloqua

**Australian Society for Antimicrobials, Adelaide. 23 - 25 February and 25 - 26 February 2017 Abstract Submission Deadline: Friday, 9 December 2016 www.antimicrobials2017.com

** 10th Pharmaceutical Care Network Europe (PCNE) Working Conference ‘Lead – Engage- Disseminate’ 1 - 4 February 2017 in Bled, Slovenia. http://www.pcne.org/conference/23/10th-pcne-working-conference-2017

**ISMP CHA Medication Safety Intensive, Sydney, March 9-10 2017. Early bird ends 31 October 2016 https://children.wcha.asn.au/ismp_medsafety

**CADTH Symposium, April 23, 2017 - April 25, 2017: Shaw Centre, Ottawa, Ontario https://www.cadth.ca/events/2017-cadth-symposium

**2017 NSW Patient Experience Symposium, 1st-2nd May 2017 Bay 4, Australian Technology Park, Eveleigh NSW (Abstract submissions close COB extended to 18th November 2016) http://www.alignmentevents.com.au/sh_events/2017-nsw-patient-experience-symposium-call-for- abstracts/#1473648903182-6aa8fa3c-649b

You are receiving this email because you or a workplace colleague has requested TAG Mail. NSW TAG analyses uptake of TAG Mail (email openings and clicks on specific contents) in order to optimise the TAG Mail service for our members and colleagues. By requesting TAG Mail, you are also agreeing to have your data (email address, country of abode) captured. All information obtained is used in accordance with NSW Health Privacy Policy. Please contact NSW TAG at [email protected] if you have any questions regarding this.