The 10Th SINO-US Chemistry Professors Conference

Program (会议日程)

The 10th SINO-US Chemistry Professors Conference Jinan, China June 15-17, 2014

Date Program & Venue Chairperson June 15 Check-in (舜耕山庄 Shungeng Hill View Hotel) Hao Fang & (Sunday) Minyong Li

June 16 Opening Ceremony & Plenary Lectures Chairperson (Monday) (报告厅 Lecture Hall) 8:30-9:00 Opening Ceremony Hao Fang 9:00-9:30 Gunda I. Georg (University of Minnesota) Binghe Wang Small Molecule Probes and Leads for Male Contraception and Cancer 9:30-10:00 Take Pictures and Coffee Break 10:00-10:30 Zhongyin Zhang (Indiana University School of Medicine) Xinshen Ye Drugging the Undruggable: Therapeutic Potential of Targeting the Protein Tyrosine Phosphatases 10:30-11:00 Binghe Wang (Georgia State University) Xiaodong Shi Inducing MDM2 degradation as an anticancer strategy 11:00-12:30 Buffet (重华堂 Chonghua Hall)

June 16 Section I Organic Chemistry Chairperson (Monday) (会见厅 VIP Hall) 13:30-13:50 Xumu Zhang (Wuhan University) Robin Practical Catalytic Hydrogenation Yonggui Chi 13:50-14:10 Xuefeng Jiang (East China Normal University) Sulfur Atom Transfer (SAT) Reaction and Synthesis of Sulfur- Containing Drugs and Natural Products 14:10-14:30 Fushun Liang (Northeast Normal University) Cascade reactions of activated cyclopropanes toward aza/oxa- heterocycles 14:30-14:50 Robin Yonggui Chi (Nanyang Technological University) Xumu Zhang Opportunities with NHC Organocatalysis: Toward New Activation Modes 14:50-15:10 Ang Li (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences) Total Synthesis of Sespenine: a Bio-Inspired Aza-Prins Approach 15:10-15:30 Coffee Break 15:30-15:50 Weiping Tang (University of Wisconsin) Hao Xu Rh(I)-catalyzed Tandem Annulation and Cycloaddition for the Synthesis of Privileged Heterocycles 15:50-16:10 Qing Gu (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences) Enantioselective Synthesis of Planar Chiral Ferrocenes via Pd- Catalyzed Direct C-H Bond Arylation 16:10-16:30 Sunliang Cui (Zhejiang University) Rh(III)-Catalyzed Cyclization and Desymmetrization for Heterocycles Synthesis 16:30-16:50 Hao Xu (Georgia State University) Weiping Tang Iron-Catalyzed Nitrogen Atom Transfer for Stereoselective Difunctionalization of Unsaturated Hydrocarbons 16:50-17:10 Bingfeng Shi (Zhejiang University) Pd-Catalyzed C (sp3)-H Bonds Functionalization: Synthetic Scope and Application 17:10-17:30 Meixin Zhao (East China University of Science and Technology) Cinchona alkaloid derivatives catalyzed diastereo- and enantioselective Mannich-type reactions of isocyanoacetates with ketimines 18:00-20:00 Welcome Dinner Reception (重华堂 Chonghua Hall) Fengshan Wang

June 17 Section I Organic Chemistry Chairperson (Tuesday) (会见厅 VIP Hall) 8:00-8:20 Andrew Evans (Queen’s University) Gong Cheng Development of Higher-Order Carbocyclization Reactions: Emulating Terpene Biosynthesis 8:20-8:50 Yuehai Shen (Kunming University of Science and Technology) Studies towards convergent total synthesis of autolytimycin 8:50-9:10 Weiliang Duan (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences) Palladium-Catalyzed Asymmetric Synthesis of Chiral Phosphorus Compounds 9:10-9:30 Xiaodong Shi (West Virigina University) Andrew Evans Triazole-Gold and Triazole-Pd Pormoted Catalysis 9:30-9:50 Renhua Fan (Fudan University) Break and Rebuild the Aromaticity:Application of Dearomatization Strategy in the Synthesis of Heterocyclic Compounds 9:50-10:10 Zhihui Shao (Yunnan University) Structural Unit-Directed Asymmetric Catalysis and Divergent Total Synthesis 10:10-10:30 Coffee Break 10:30-10:50 Gong Cheng (Penn State University) Xiaodong Shi Development of Useful C-H Functionalization Chemistry for Organic Synthesis 10:50-11:10 Hegui Gong (Shanghai University) Ni-catalyzed reductive coupling of tertiary alkyl halides 11:10-11:30 Shouyun Yu (Nanjing University) De novo synthesis of nitrogen aromatic compounds enabled by somophilic isocyanide insertions 11:30-11:50 Shuanhu Gao (East China Normal University) Total Synthesis of Bioactive Natural Products: Taiwaniaquinol B and Gracilamine 12:00-13:00 Buffet (重华堂 Chonghua Hall)

June 17 Section I Organic Chemistry Chairperson (Tuesday) (拱北楼四楼会议室 The 4th Floor Meeting Room, Gongbei Building) 13:30-13:50 Lei Liu (Shandong University) Zhenghu Xu Catalytic enantioselective C-H functionalization of heterocycles 13:50-14:10 Jian Xiao (Qingdao Agricultural University) sp3 C-H functionalization of azarenes under metal free and catalyst free conditions 14:10-14:30 Huadong Xu (Changzhou University) A novel cyclization/aza-Claisen rearrangement cascade initiated by ketenimine formation: highly efficient synthesis of β-allyl cyclic amidines 14:30-14:50 Zhenghu Xu (Shandong University) Lei Liu Tandem Metal Relay Catalysis for Heterocycles 14:50-15:10 Zhenghui Guan (Northwest University) Synthesis of azaheterocycles via cyclization of enamides and alkynes 15:10-15:30 Shifa Zhu (South China University of Technology) Transition Metal-Catalyzed Generation and Trapping of the o- QDMs: The Applications in the Diels-Alder reactions 15:30-15:50 Xu Cheng (Nanjing University) Enantioselective Construction of Chiral Carboniolamide 16:00-16:30 Closing Ceremony Hao Fang (拱北楼四楼会议室 The 4th Floor Meeting Room, Gongbei Building) 18:00-19:00 Buffet (重华堂 Chonghua Hall)

June 16 Section II Bioorganic Chemistry Chairperson (Monday) (会谈厅 Meeting Hall) 13:30-13:50 Zhongwu Guo (Wayne State University) Xiangming Synthesis and Biological Studies of GPI Anchors and GPI- Guan Anchored Proteins 13:50-14:10 Yu Rao (Tsinghua University) Developing Novel Chemical Probes for Early Drug Discovery 14:10-14:30 Zheng Yin (Nankai University) Discovery of Enterovirus 71 3C Protease Inhibitors 14:30-14:50 Xiangming Guan (South Dakota State University) Zhongwu Guo A combined inhibition of lactate dehydrogenase and pyruvate dehydrogenase kinase through the use of oxamate and dichloroacetate, and their prodrugs as a novel approach for cancer growth inhibition 14:50-15:10 Xichen Lin （GSK China） Identification of S1P1 Agonists for the Treatment of Multiple Sclerosis 15:10-15:30 Coffee Break

15:30-15:50 Yujun Zheng (The University of Georgia) Wenfang Xu Bioorthogonal Chemical Probes of Protein Lysine Acetyltransferases 15:50-16:10 Zongbao Zhao (Dalian Institute of Chemical Physics, Chinese Academy of Sciences) Protein methylation in yeast 16:10-16:30 Qingsong Liu (High Magnetic Field Laboratory, Chinese Academy of Sciences) Discovery of a super potent BTK kinase inhibitor which induce strong protein degradation 16:30-16:50 Li Niu (University at Albany, State University of New York) Xinyong Liu Developing chemical inhibitors and RNA aptamers against AMPA receptor channels 16:50-17:10 Peng Chen（Peking University） Deprotection Chemistry-mediated Protein Activation in Living Cells 17:10-17:30 Yi Tang (University of California, Los Angeles) Exciting New Enzymes from Fungal Biosynthetic Pathways 18:00-20:00 Welcome Dinner Reception (重华堂 Chonghua Hall) Fengshan Wang

June 17 Section II Bioorganic Chemistry Chairperson (Tuesday) (会谈厅 Meeting Hall) 8:00-8:20 Bin Xu (Virginia Tech) Qian Wang Molecular Mechanisms of Amylin as a Novel Contributor to Alzheimer’s Disease and Natural Product Inhibitor Discovery 8:20-8:50 Haibing Zhou (Wuhan University) Novel Selective Estrogen Receptor Modulators (SERMs): Protein- Ligand Interactions and the Dual Regulation Mechanism Study 8:50-9:10 Luqing Shang (Nankai University) Discovery of anti-HCV Agents 9:10-9:30 Qian Wang (University of South Carolina) Diwan S Probing reversible click reactions at the single-molecule level Rawat 9:30-9:50 Xiaohua Peng (University of Wisconsin Milwaukee) Inducible DNA Cross-Linking Agents as Selective Anticancer Drugs 9:50-10:10 Wei Li (University of Tennessee Health Science Center) Discovery of novel tubulin inhibitors for metastatic melanoma 10:10-10:30 Coffee Break 10:30-10:50 Diwan S Rawat (University of Delhi) Bin Xu Identification of Lead Antimalarial Through Rational Drug Design 10:50-11:10 Bingui Wang (Institute of Oceanology, Chinese Academy of Sciences) In vitro and in vivo anticancer evaluation of norditerpenoids from the marine alga-derived endophytic fungus Aspergillus wentii 11:10-11:30 Dianqing Sun (University of Hawaii at Hilo) Natural Product-Inspired Novel Antibacterial Agents 11:30-11:50 Bin He (Guiyang Medical University) Development of Mechanism-based Inhibitors for Sirtuins 12:00-13:00 Buffet (重华堂 Chonghua Hall) 16:00-16:30 Closing Ceremony (拱北楼四楼会议室 The 4th Floor Meeting Hao Fang Room, Gongbei Building) 18:00-19:00 Buffet (重华堂 Chonghua Hall)

June 16 Section III Materials and Applied Chemistry Chairperson (Monday) (第六会议室 No.6 Conference Room) 13:30-13:50 Wenfang Sun (North Dakota State University) Guijun Wang Heteroleptic cationic iridium complexes: Synthesis, photophysics and nonlinear absorption 13:50-14:10 Yonghai Chai (Shanxi Normal University) New type of aza-MBH reaction and its application to one-pot efficient synthesis of highly substituted dihydropyrroles 14:10-14:30 Guangxi Zhai (Shandong University) Hyaluronic acid-quercetin conjugate micelles: Synthesis, characterization, in vitro and in vivo evaluation 14:30-14:50 Guijun Wang (Old Dominion University) Wenfang Sun Design, synthesis, and characterization of a series of functional glycoclusters 14:50-15:10 Jun Li (National University of Singapore) Smart Supramolecular Nano Drug/Gene Carriers Self- Assembled from Functional Polymers 15:10-15:30 Coffee Break 15:30-15:50 Xiaogang Liu (National University of Singapore) Liang Xue Upconversion Nanocrystals: A New Class of Luminescent Bioprobes 15:50-16:10 Wei Zhang (University of Colorado Boulder) Novel Shape-Persistent Organic Molecular Cages and Their Biological Activity 16:10-16:30 Yongsheng Zhao (Institute of Chemistry, Chinese Academy of Sciences) Organic Nanophotonic Materials and Devices 16:30-16:50 Liang Xue (University of the Pacific) Xiaogang Liu Targeting Telomeric G-quadruplex DNA with Phenanthroline Based Metal Complexes 16:50-17:10 Jia Sheng (University at Albany, State University of New York) Crystal Structure Studies of 2’-5’-linked RNA 17:10-17:30 Guodong Liu (North Dakota State University) Nucleic Acid-Based Lateral Flow Biosensors for Biomedical and Environmental Applications 17:30-17:50 Yaoqun Li (Xiamen University) Hot-spot surface plasmon-coupled directional emission and its biosensing applications 18:00-20:00 Welcome Dinner Reception (重华堂 Chonghua Hall) Fengshan Wang

June 17 Section III Materials and Applied Chemistry Chairperson (Tuesday) (第六会议室 No.6 Conference Room) 8:00-8:20 Jian Liu (University of North Carolina) Haoru Sun Chemoenzymatic synthesis of low molecular weight heparins 8:20-8:50 Yongshu Xie (East China University of Science and Technology) Ion probes based on linear and macrocyclic polypyrroles 8:50-9:10 Jiayu Zhou (Shimadzu China) 新型高效高纯度粉末化技术(C2P)用于化学合成物及天然产物的纯化与干燥 9:10-9:30 Haoran Sun (University of South Dakota) Lixin Zhang Fluorinated Materials for a Sustainable World: from Energy Harvesting and Storage to Biomedical Applications 9:30-9:50 Hongzhi Cao (Shandong University) Substrate engineering directed chemoenzymatic synthesis of sialosides 9:50-10:10 Chu Wang (Peking University) A Chemoproteomic Platform to Quantitatively Map Targets of Lipid-derived Electrophiles 10:10-10:30 Coffee Break 10:30-10:50 Lixin Zhang (Institute of Microbiology, Chinese Academy of Jian Liu Sciences) Bioprospecting Novel Marine Natural Products for Potential Anti- infective Drugs 10:50-11:10 Xinjing Tang (Peking University) Bioorthogonal SERS Nanoprobes for Tumor Targeting and Spectroscopic Detection 11:10-11:30 Qianbin Li (Central South University) Novel anti-NSCLC strategy: Dual inhibition of RAF/MEK/ERK and PI3K/AKT/mTOR signaling pathways with small molecules 11:30-11:50 Yawen Wang (Lanzhou University) Merging of Supramolecular Chemistry Approach and Specific Reactions: Development of Several Fluorescent Chemosensors and Chemodosimeters 12:00-13:00 Buffet (重华堂 Chonghua Hall) 16:00-16:30 Closing Ceremony (拱北楼四楼会议室 The 4th Floor Meeting Hao Fang Room, Gongbei Building) 18:00-19:00 Buffet (重华堂 Chonghua Hall) June 18 Check-out (舜耕山庄 Shungheng Hill View Hotel) Hao Fang & (Wednesday) Minyong Li