Figure S1: USA population structure with respect to region, age group, and ethnicity, 20032007. AA: African-American women; CA: Caucasian-American women. Figure S2: Corpus uteri cancer incidence rates with respect to age group and ethnicity in the South region of USA, 20032007. (a) Age-specific rates per 100,000. (b) Corpus uteri cancer burden distribution or expected number of cases; estimation based on observed age-specific incidence rates and the world-standard population. a) b)

Table S1: Age-standardized rate (ASR), rate ratio (RR), 95% confidence interval (CI), and median age at diagnosis (Median Age) for corpus uteri cancer with respect to ethnicity, state, region, and time period [19982002 (9802) and 20032007 (0307)].

African American Number of Cases ASR RR, 95% CI Median Age State/Region 98‘02 03 ‘07 9802 0307 0307 versus 9802 9802 0307 1.1 1.0 1.1 New York 1,549 2,091 15.78 17.34 0 3 7 63 69 1.0 0.9 1.2 New Jersey 575 659 14.76 15.81 7 6 0 65 63 1.3 1.0 1.6 Connecticut 124 184 13.70 18.12 2 5 6 63 57 1.1 1.0 1.2 Pennsylvania 578 709 13.66 15.73 5 3 9 65 65 Massachusetts  181  14.89     63 Rhode Island  22  13.05     64 Northeast 2,826 3,846 14.99 16.77 1.12 1.07 1.17 64 64 1.0 0.9 1.1 Florida 951 1,188 14.14 14.83 5 6 4 66 64 1.2 1.0 1.3 Alabama 429 548 11.32 13.85 2 8 9 67 65 1.0 0.9 1.1 Texas 775 922 11.66 11.77 1 2 1 65 63 1.0 0.9 1.2 Louisiana 521 462 11.93 12.99 9 6 3 66 63 1.0 0.9 1.1 Georgia 739 976 12.09 12.82 6 6 7 64 62 1.1 0.9 1.2 South Carolina 519 640 13.74 15.05 0 8 3 66 66 North Carolina  885  14.25     64 Virginia  632  12.86     64 Arkansas  165  11.78     66 Tennessee  355  11.80     62 Delaware  96  18.65     63 Oklahoma  97  11.88     58    District of Columbia 215  13.39  68  South 4,149 6,966 13.57 13.40 1.07 1.03 1.11 66 63 0.9 0.8 1.1 Missouri 268 291 13.86 13.58 8 3 6 66 62 1.2 1.1 1.3 Illinois 756 977 12.75 15.48 1 0 4 63 64 1.1 1.0 1.2 Michigan 611 740 14.41 16.20 2 1 5 64 63 1.0 0.9 1.2 Ohio 523 615 12.33 13.29 8 6 1 65 66 Indiana  234  14.58     63 Wisconsin  115        Nebraska  30  15.99     62 Midwest 2,158 3,002 13.21 14.87 1.13 1.07 1.19 65 63 California 879 1,068 13.96 1.1 1.0 1.2 63 63 12.68 0 1 0 Arizona  74  13.48     63 Colorado  59  12.07     60 Oregon  18  11.01     63 West 879 1,219 12.69 13.79    63 62 Caucasian American 1.0 1.0 1.0 New York 12,287 13,029 20.59 21.43 4 2 7 64 63 1.0 0.9 1.0 New Jersey 6,039 6,227 22.07 22.14 0 7 4 65 63 1.0 0.9 1.0 Connecticut 2,628 2,692 21.03 21.09 0 5 6 65 63 1.0 0.9 1.0 Pennsylvania 10,565 10,864 23.06 23.17 0 8 3 64 63 Massachusetts  5,133  21.86     62 Rhode Island  865  21.68     61 21.6 Northeast 31,519 38,810 7 22.57 1.04 1.03 1.06 64 62 0.9 0.9 1.0 Florida 9,590 9,904 14.85 14.61 8 6 1 67 69 1.1 1.0 1.1 Alabama 1,574 1,761 11.40 12.62 1 3 8 65 62 1.0 0.9 1.0 Texas 7,526 8,479 12.93 13.27 3 9 6 63 61 0.9 0.8 1.0 Louisiana 1,471 1,109 12.80 11.91 3 6 1 63 62 0.9 0.9 1.0 Georgia 2,715 2,981 13.54 13.27 8 3 3 62 61 1.0 0.9 1.1 South Carolina 1,484 1,712 13.04 13.66 5 8 2 64 63 North Carolina  4,004  15.25     62 Virginia         62 Arkansas         63 Tennessee  2,783  13.67     62 Delaware         62 Oklahoma  1,651  13.63     64    District of Columbia 110  16.79  64  16.6 South 24,470 39,764 8 14.07 0.84 0.83 0.86 64 63 0.9 0.9 1.0 Missouri 3,521 3,597 17.96 17.39 7 2 1 65 63 1.0 1.0 1.1 Illinois 6,999 7,685 18.61 19.83 7 3 0 64 62 1.0 0.9 1.0 Michigan 6,164 6,649 19.57 20.02 2 9 6 63 62 1.0 1.0 1.0 Ohio 7,592 8,127 19.49 20.16 3 0 7 63 62 Indiana  4,156  19.00     62 Wisconsin  3,873  19.60     62 Nebraska  1,253  19.40     63 19.0 Midwest 24,276 35,340 3 19.54 1.03 1.01 1.04 64 62 0.9 0.9 0.9 California 12,920 15,940 17.75 16.44 3 1 5 66 61 Arizona  2,563  12.84     62 Colorado  2,152  14.22     61 Oregon  2,339  17.21     62 17.7 West 12,920 22,994 6 15.80    66 62