Autoantibody Profile in Indian Patients with Myositis

Supplementary Table 1. Clinical and Demographic Profile of patients with IIM in our cohort.

Parameter Total sera DM Sera PM Sera JDM Sera CTD-Myositis P value n (%) n (%) n (%) Sera n (%) No. of patients (%) 124 (100) 55 (44.3) 25 (20.2) 22 (17.7) 22 (17.7) --- Clinical Features Proximal weakness 121 (97.5) 54 (98.1) 25 (100) 20 (90.9) 22 (100) 0.314 Pharyngeal weakness 34 (27.4) 21 (38.1) 6 (24.0) 4 (18.1) 3 (13.6) 0.094 Functional class IV 19 (15.3) 11 (20.0) 4 (16.0) 1 (4.5) 3 (13.6) ------Fever 54 (43.5) 22 (40.0) 7 (28.0) 16 (72.7) 9 (40.9) 0.015 Weight loss 55 (44.3) 18 (32.7) 9 (36.0) 13 (59.0) 15 (68.1) 0.013 Arthritis 52 (41.9) 18 (32.7) 10 (40.0) 6 (27.2) 18 (81.8) <0.001 ILD* 28 (22.6) 12 (21.8) 8 (32.0) 2 (9.0) 6 (27.2) 0.278 PAH# 10 (8.0) 3 (5.4) 1 (4.0) 0 (0.0) 6 (27.2) 0.003 Mechanics Hand 22 (17.4) 12 (21.8) 7 (28.0) 2 (9.0) 1 (4.5) 0.103 Raynauds 32 (25.8) 7 (12.7) 8 (32.0) 1 (4.5) 16 (72.7) <0.001 Phenomenon Calcinosis 6 (4.8) 2 (3.6) 0 (0.0) 4 (18.1) 0 (0.0) 0.010 Skin rash 91 (73.4) 54 (98.1) 7 (28.0) 21 (95.4) 9 (40.9) <0.001 Diffuse Skin rash 30 (24.2) 18 (32.7) 0 (0.0) 10 (45.4) 2 (9.0) <0.001 Gottron’s rash 45 (36.3) 27 (49.0) 0 (0.0) 17 (77.3) 1 (4.5) <0.001 Heliotrope rash 46 (37.0) 31 (56.3) 0 (0.0) 14 (63.6) 1 (4.5) <0.001 V Sign 13 (10.5) 10 (18.1) 0 (0.0) 3 (13.6) 0 (0.0) 0.027 Shawl sign 11 (8.8) 9 (16.3) 0 (0.0) 2 (9.0) 0 (0.0) 0.038 Non-healing Ulcers 16 (12.9) 8 (14.5) 0 (0.0) 8 (36.3) 0 (0.0) <0.001 Alopecia 42 (33.8) 15 (27.2) 3 (12.0) 10 (45.4) 14 (63.6) 0.001 Oral ulcers 37 (29.8) 15 (27.2) 4 (16.0) 6 (27.2) 12 (54.5) 0.030 Myocarditis 2 (1.6) 1 (1.8) 0 (0.0) 1 (4.5) 0 (0.0) ---- Gastrointestinal Bleed 3 (2.4) 1 (1.8) 1 (4.0) 0 (0.0) 1 (4.5) 0.725 Follow up Details Disease Relapse 40 (32.2) 19 (34.5) 5 (20.0) 9 (40.9) 7 (31.8) 0.456 Mortality 4 (3.2) 3 (5.4) 0 (0.0) 0 (0.0) 1 (4.5) 0.460 * Interstitial Lung Disease #Pulmonary Artery Hypertension