Autoantibody Profile in Indian Patients with Myositis

Autoantibody Profile in Indian Patients with Myositis

<p>Supplementary Table 1. Clinical and Demographic Profile of patients with IIM in our cohort.</p><p>Parameter Total sera DM Sera PM Sera JDM Sera CTD-Myositis P value n (%) n (%) n (%) Sera n (%) No. of patients (%) 124 (100) 55 (44.3) 25 (20.2) 22 (17.7) 22 (17.7) --- Clinical Features Proximal weakness 121 (97.5) 54 (98.1) 25 (100) 20 (90.9) 22 (100) 0.314 Pharyngeal weakness 34 (27.4) 21 (38.1) 6 (24.0) 4 (18.1) 3 (13.6) 0.094 Functional class IV 19 (15.3) 11 (20.0) 4 (16.0) 1 (4.5) 3 (13.6) ------Fever 54 (43.5) 22 (40.0) 7 (28.0) 16 (72.7) 9 (40.9) 0.015 Weight loss 55 (44.3) 18 (32.7) 9 (36.0) 13 (59.0) 15 (68.1) 0.013 Arthritis 52 (41.9) 18 (32.7) 10 (40.0) 6 (27.2) 18 (81.8) <0.001 ILD* 28 (22.6) 12 (21.8) 8 (32.0) 2 (9.0) 6 (27.2) 0.278 PAH# 10 (8.0) 3 (5.4) 1 (4.0) 0 (0.0) 6 (27.2) 0.003 Mechanics Hand 22 (17.4) 12 (21.8) 7 (28.0) 2 (9.0) 1 (4.5) 0.103 Raynauds 32 (25.8) 7 (12.7) 8 (32.0) 1 (4.5) 16 (72.7) <0.001 Phenomenon Calcinosis 6 (4.8) 2 (3.6) 0 (0.0) 4 (18.1) 0 (0.0) 0.010 Skin rash 91 (73.4) 54 (98.1) 7 (28.0) 21 (95.4) 9 (40.9) <0.001 Diffuse Skin rash 30 (24.2) 18 (32.7) 0 (0.0) 10 (45.4) 2 (9.0) <0.001 Gottron’s rash 45 (36.3) 27 (49.0) 0 (0.0) 17 (77.3) 1 (4.5) <0.001 Heliotrope rash 46 (37.0) 31 (56.3) 0 (0.0) 14 (63.6) 1 (4.5) <0.001 V Sign 13 (10.5) 10 (18.1) 0 (0.0) 3 (13.6) 0 (0.0) 0.027 Shawl sign 11 (8.8) 9 (16.3) 0 (0.0) 2 (9.0) 0 (0.0) 0.038 Non-healing Ulcers 16 (12.9) 8 (14.5) 0 (0.0) 8 (36.3) 0 (0.0) <0.001 Alopecia 42 (33.8) 15 (27.2) 3 (12.0) 10 (45.4) 14 (63.6) 0.001 Oral ulcers 37 (29.8) 15 (27.2) 4 (16.0) 6 (27.2) 12 (54.5) 0.030 Myocarditis 2 (1.6) 1 (1.8) 0 (0.0) 1 (4.5) 0 (0.0) ---- Gastrointestinal Bleed 3 (2.4) 1 (1.8) 1 (4.0) 0 (0.0) 1 (4.5) 0.725 Follow up Details Disease Relapse 40 (32.2) 19 (34.5) 5 (20.0) 9 (40.9) 7 (31.8) 0.456 Mortality 4 (3.2) 3 (5.4) 0 (0.0) 0 (0.0) 1 (4.5) 0.460 * Interstitial Lung Disease #Pulmonary Artery Hypertension</p><p>1</p>

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