The Fundamentals of Human Genetics and Genomics

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THE FUNDAMENTALS OF HUMAN GENETICS AND GENOMICS Duration 5 days of face-to-face teaching plus self-directed learning Cost: £1250. If you are an NHS employee, full funding is available through Health Education England Tutors: Dr Kate Everett – St George’s University of London Genetics Research Centre, Reader in Human Genetics Prof Guy Tear – King’s College London, Prof of Molecular Neurobiology Location: St George’s University of London This module will cover the key elements of human molecular genomics which students need as standalone knowledge and to provide a foundation for further modules within Genomic Medicine. Students will learn about the structure of the genome and genes, how genetic information is transferred from DNA to protein, about different patterns of inheritance and different types of genetic variation, and how scientists and clinicians try to identify disease genes and mutations. AIMS • Prepare students to understand the role of genetics in disease and how genomic information can be utilised to elucidate disease mechanism and biology, and its role in personalised medicine. • Serve as a foundation for those wishing to advance their careers within the NHS in genomic medicine. LEARNING OUTCOMES By the end of this module the student will be able to: • Explain core elements of genome architecture, including the properties of DNA and chromatin structure • Critically evaluate the regulation of gene expression, transcription and translation • Interpret variation in genome structure and sequence in the context of physiological function and disease, and across human populations • Describe the correlation between genotype and phenotype ENTRY REQUIREMENTS Applicants should have a minimum of a lower second class degree (2:2) in a subject that offers an appropriate grounding in science, genetics or healthcare. Alternative professional qualifications may be considered. PREREQUISITES We offer Massive Open Online Courses (MOOCs) which you can study online to deepen your understanding. We suggest the following courses: The Genomics Era: the Future of Genetics in Medicine Genomic Technologies in Clinical Diagnostics: Molecular Techniques Genomic Technologies in Clinical Diagnostics: Next Generation Sequencing These courses are available at: www.futurelearn.com/partners/sgul More information at kcl.ac.uk/genomicmedicine Apply via sgul.ac.uk/genomics 110608(H).

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