SOM IACUC Protocol

Version 7.2016

Section D11: Physical Restraint

Physical Restraint Physical restraint is the use of manual or mechanical means to limit some or all of an animal’s normal movement, in the absence of anesthesia, for the purpose of examination, collection of samples, drug administration, therapy, or experimental manipulation. Such restraint may cause distress and/or pain if prolonged or if not carried out properly. Acclimation and habituation techniques may be used to reduce levels of discomfort from stress associated with this procedure. Depending on the level of restraint (minimal, partial and complete) and duration of restraint, it is classified as momentary, short-term or prolonged. Prolonged restraint may qualify as USDA Pain Classification E.

Note: If an animal fails to adapt to the restraint devise, the animal must be removed from the study.

Duration of Restraint  Momentary Physical Restraint – 5 minutes or less  Short-Term Physical Restraint – Between 5 and 30 minutes  Prolonged Physical Restraint – Greater than 30 minutes Please Select the Degree of Restraint Please Indicate the Duration of the Restraint Minimal Physical Restraint – rotational movement of the body can occur; no portion of the body is completely immobilized Partial Physical Restraint – one or more immobilized body parts, allowing some movement (e.g: most rodent restraint devices) Complete Physical Restraint – Most body parts are immobilized, little to no normal movement is possible. Includes use of paralytic agents. Provide justification for the use of restraint:

Please describe the following:  How the animals will be acclimated to the restraint.  The number of times an individual animal will be subjected to restraint.  How the animal will be monitored and cared for during and after restraint.

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