2 Seeing Sepsis Video Fact Sources

Video fact sources

In the U.S., nearly one million new cases of http://medicalcenter.osu.edu/pdfs/about_osumc/sepsis.pdf. The sepsis occur each year, increasing by nine Ohio State University Medical Center, 2011 percent every year. Sepsis is involved in nearly one in five deaths in http://www.sepsisalliance.org/downloads/2012_media_kit_fact_ US hospitals. sheet_sepsis.pdf. Sepsis Alliance Sepsis has been named as the most expensive http://www.hcup-us.ahrq.gov/reports/statbriefs/sb160.jsp. in-patient cost in American hospitals in 2011 at Agency for Healthcare Research and Quality, Healthcare Cost over $20 billion each year. and Utilization Project, Statistical Brief #160, 2013 Forty percent of patients diagnosed with severe http://www.sepsisalliance.org/faq/. Sepsis Alliance sepsis do not survive. Until a cure for sepsis is found, early detection is the surest hope for survival. Research has shown that early recognition and http://www.sepsisalliance.org/downloads/Sepsis_Clinical_Fact_ treatment of severe sepsis reduces morbidity Sheet.pdf. The Ohio State University Medical Center, 2011 and mortality and will save lives. Dr. Larson (Definitions #4) Sepsis killed 258,000 people in the United http://www.sepsisalliance.org/downloads/2012_media_kit_fact_ States in 2009 – one person every 2 minutes. sheet_sepsis.pdf. Sepsis Alliance, 2012

Sepsis remains a salient problem in critical care Wang HE, Shapiro NI, Angus DC, Yealy DM, “National and emergency medicine, accounting for more estimates of severe sepsis in United States emergency than 500,000 ED visits per year. departments.” Critical Care Medicine 2007;35(8):1928-36. Seniors (65+) are 11 times more likely to be http://www.sepsisalliance.org/downloads/2012_media_kit_fact_ hospitalized with sepsis and are significantly sheet_sepsis.pdf. Sepsis Alliance, 2012 more likely to die from sepsis. The mortality rate of sepsis is 0-60% per year. Melamed A, Sorvillo FJ,” The burden of sepsis-associated mortality in the United States from 1999-2005: an analysis of multiple cause-of-death data.” Critical Care. 2009;13:R28.

Jacobi J., “Pathophysiology of sepsis.” American Journal of Health-System Pharmacy. 2002;59 (suppl 1):S3-8. More than 42,000 children develop severe http://www.sepsisalliance.org/downloads/2012_media_kit_fact_ sepsis each year. Approximately 4,400 of these sheet_sepsis.pdf. Sepsis Alliance, 2012 children die, more than the number children who die from pediatric cancers. Mortality from sepsis rises to 75% to 80% when http://www.sepsisalliance.org/downloads/2012_media_kit_fact_ four or more organs fail. sheet_sepsis.pdf. Sepsis Alliance, 2012 Sepsis is common and often deadly. It remains http://www.world-sepsis-day.org/? the primary cause of death from infection, MET=SHOWCONTAINER&vCONTAINERID=11. World Sepsis despite advances in modern medicine like Day, 2014 vaccines, antibiotics, and intensive care. Every year, severe sepsis strikes about 750,000 Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Americans. It’s been estimated that between Pinsky MR, “Epidemiology of severe sepsis in the United States: 28 and 50 percent of these people die —far analysis of incidence, outcome and associated costs of care.” more than the number of U.S. deaths from Critical Care Medicine . 2001 Jul;29(7):1303-10 prostate cancer, breast cancer and AIDS combined. Wood KA, Angus DC, “Pharmacoeconomic implications of new therapies in sepsis.” PharmacoEconomics . 2004;22(14):895- 906 1 — Seeing Sepsis | Video fact sources “Every hour a patient in septic shock doesn't Kumar, A., Haery, C., Paladugu, B., Kumar, A., Symeoneides, receive antibiotics, the risk of death increases S., Taiberg, L., & Parrillo, J. E. (2006), “The duration of 7.6%” hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels.” Journal of Infectious Diseases . 193(2), 251-258.