Children and Young Adults with Crohns and Colitis

children and young adults with crohns and colitis

CROHN’S IN CHILDHOOD RESEARCH ASSOCIATION Parkgate House, 356 West Barnes Lane, Motspur Park, Surrey KT3 6NB Tel: 020 8949 6209 website: www.cicra.org e-mail: [email protected] Reg.Charity Nos 278212 & SC040700

PhD STUDENTSHIP Guidance Notes

Applications are invited from academic institutions with suitable facilities for scientific research and in a position to carry out the training and supervision of a three-year full- time PhD Studentship relevant to children with Inflammatory Bowel Disease. All applications must include a paediatric gastroenterologist as co-applicant.

Applications should be made by the proposed Supervisor through their Head of Department and sent electronically to [email protected] by 12 noon Friday 14th October 2016. All pages of the application must be put together into one PDF document and clearly titled with the applicants name and institution. Receipt of applications will be acknowledged, but if the application is not in the correct format it will not be considered for funding.

Only one CICRA PhD studentship may be held by the same Department at any one time.

Unless the supervisor is a paediatric gastroenterologist there must be one included as a co-applicant.

CICRA will award the grant for a three-year term and the stipend and fees will be paid in accordance with the appropriate institutional and UK rates. An additional small discretionary grant for consumables equal to the current Research Council grants rate will also be paid.

All applications will undergo independent peer review.

Any queries relating to the submission of an application must be referred, in the first instance, to the CICRA Grants Administrator at the above address who will liaise with the CICRA Trustee(s) responsible for grants. Applicants must not contact a member of the CICRA Awards Advisory Panel to discuss any aspect of an application, or the decision reached.

CICRA PhD Studentship Sept 2013 Upon awarding of the grant, full Terms & Conditions will be sent and must be signed by all concerned. Please note that failure to fulfil these grant conditions may result in immediate termination of the grant and/or jeopardise future grant applications.

CICRA PhD Studentship Sept 2013 children and young adults with crohns and colitis

PhD STUDENTSHIP Conditions of Acceptance

In accordance with the Charity Commission’s principles governing the funding of medical research by charities, grants made by CICRA are conditional upon the following:

 A detailed annual report on the progress of the research work is required by CICRA from the PhD Supervisor (max 500 words). Continuance of funding will depend on a satisfactory annual report, as reviewed by the Medical Advisory Panel.

 One short report per year (300- 500 words), in lay language, will be required for inclusion in the annual CICRA Newsletter.

 A summary report must be submitted at 8 months into the final year. Failure to provide this will result in CICRA withholding the final quarterly payment. If the student has not completed the laboratory work by this time, or should there be earlier delay, CICRA must be informed of the nature of the delay and of plans for its timely completion.

 Once the dissertation has been concluded and the degree awarded, a comprehensive report summarising all aspects of the research must be submitted to CICRA and its medical advisors (maximum 1000 words). A bound copy of the thesis must also be forwarded to CICRA.

 The PhD Student and/or Supervisor may be asked to attend the CICRA annual meeting to give a short presentation on the project.

 Any papers published as a result of the PhD Studentship must acknowledge the support of Crohn’s in Childhood Research Association. Copies of published papers resulting from the PhD Studentship must be sent to the CICRA office soon after publication. Any media interest resulting from the project and its conclusions should be discussed in advance with CICRA and CICRA’s role should be included in any resultant media contact.

 CICRA accepts that Intellectual Property Rights are held by the Institution carrying out the research. However, if the research is funded solely by CICRA, there is an expectation that some of the financial benefit of any

CICRA PhD Studentship Sept 2013 commercial proceeds would be shared with CICRA who must be kept informed.

children and young adults with crohns and colitis

CICRA PhD STUDENTSHIP Application Form

A. Proposed Project (This section should be completed by the Project Supervisor)

A1. Title of proposed project

______A2. Brief summary of project in lay terms (maximum of 150 words)

______A3. Has this project been submitted elsewhere/previously for funding? Yes / No (circle as appropriate). If yes, give decision or likely outcome date

______A4. Please attach a detailed description of the project. This should cover the following areas;

 the work to be undertaken, including hypothesis, brief description of methods and study design, patient/sample numbers and analysis  anticipated project timeline (simple flow diagram can be used)  description of how the project will significantly advance the body of

CICRA PhD Studentship Sept 2013 knowledge of inflammatory bowel disease, particularly as it affects children and young adults  short list of relevant references

Section A4 should be no more than three sides of A4 in length, using 1.5 line spacing and 11 point arial type B. Sponsoring Institution / Department

B1. Name and address of Institution/Department (incl. telephone/fax and email)

B2. Name, address and details of Supervisor

Surname & title: Date of Birth:

Forenames:

Address:

Telephone/fax and email:

Degrees and Diplomas:

______Current Post

Date from:

Title of post:

Institution:

Department:

Principal employer:

______

Previous posts held (with dates please, list no more than 3 with most recent first)

______Recent Grant Awards

______Most recent publications (please list no more than 5 and give citation in full)

______Relevant training

CICRA PhD Studentship Sept 2013 ______B3. Details co-Applicant Paediatric Gastroenterologist (if required and this function not fulfilled by the Supervisor/Principle Investigator)

Surname & title: Date of Birth:

Forenames:

Address:

Telephone/fax and email:

Degrees and Diplomas:

______Current Post

Date from:

Title of post:

Institution:

Department:

Principal employer: ______Previous posts held (with dates please, list no more than 3 with most recent first)

Recent Grant Awards

______Most recent publications (please list no more than 5 and give citation in full)

______Relevant training

B4. Name and address of Head of Department (incl. telephone/fax and email)

______B5. Details of Institutional Postgraduate Training Programme (max one page A4)

CICRA PhD Studentship Sept 2013 ______B6. PhD Studentships supervised/completed in the department in the last 5 years

______B7. Departmental experience in IBD research

______B8. Grant details (if known) i) Period for which support sought: ii) Proposed starting date:

______

C. PhD Candidate Background (if known)

Please note that CICRA will only support candidates with a 1st or 2.1 degree in a relevant subject.

C1. Full name

______C2. Date and place of birth

______C3. Address for correspondence (including daytime and home telephone numbers & email)

______C4. Education/Degrees/Diplomas

______C5. Practical laboratory and any other experience relevant to the Studentship

CICRA PhD Studentship Sept 2013 ______C6. Prizes and awards

______C7. Any other relevant factors

______

D. Ethical & Regulatory Considerations

D1. Experiments involving animals (circle Yes / No as appropriate)

Will the proposed project involve the use of animals? Yes No

Does your proposal involve the use of animal tissue? Yes No

Do your proposals include procedures to be carried out on animals in the UK which will require a Home Office Licence ? Yes No

Do your proposals involve the use of animals or animal tissue outside of the UK? Yes No

If Yes to D1 questions above, have personal and project licences been granted by the Home Office? Yes No

If Yes, please enter licence details here:

If No, please indicate when this is to happen and submit licence details to CICRA

Please note: Licence details must be sent to CICRA before successful applicant’s Institution receives CICRA funding.

CICRA PhD Studentship Sept 2013 If animal species to be used: please indicate which species from: Cat, Dogs, Horses and non-human Primates, Genetically altered animals and for any other animal(s) Please indicate here: ……………………………………

Explain why the use of animal(s) is necessary and whether there are other possible approaches; please include severity of procedures to be used.

A brief justification (attach one size A4 maximum) must be provided outlining the type and numbers of animals to be used, the source of animals and how they will be transported and maintained, and evidence that the species chosen is appropriate and that the minimum number used will give statistically valid results.

Please note: a) In some cases CICRA may need to seek additional animal related information from the applicant. b) That CICRA funded research should conform to the 3Rs principles and the National Centre for Replacement, Refinement and Reduction of Animals in Research (NC3Rs) Guidelines ______D2. Does the project involve any experiments with genetically modified organisms or does it involve the use of genetic manipulation techniques? (If yes, please explain) Yes No

______D3. Is the proposed research likely to lead to patentable or commercially exploitable results? Yes No

______D4. Will the proposed project involve patients/human subjects OR patient material/samples? Yes No

If Yes, how many patients/subjects will be involved in total?

Please give status of ethical committee approval (ring where appropriate):

UNNECESSARY TO BE SUBMITTED PENDING APPROVED

Please attach written approval as granted by your Ethics Committee but if approval UNNECESSARY, please state why:

Please note that: If ethics approval is pending at the time of application, funding (although not an award decision in principle) remains conditional on this being secured and CICRA will not award any studentship until the Trustees are in receipt of a copy of the full transcript of the relevant ethics committees’ written confirmation of approval. ______

CICRA PhD Studentship Sept 2013 PhD STUDENTSHIP

Declaration

We have read the CICRA PhD Studentship application criteria and in the event of a grant being awarded agree to abide by them and any amendments that may subsequently be issued. I/we shall be actively engaged in, and in day-to-day control of, the project. CICRA will be informed as soon as I/we hear the outcome of any other applications for funding for the proposed project and/or any significant changes to this proposal.

Contact telephone/extension number of Project Supervisor (Direct Line, if possible) ……………………………..

To be signed by: Signature Name in block capitals Date HEAD OF DEPARTMENT PROJECT SUPERVISOR

This application should be submitted by/through i) the Head of Department and ii) the Institutional Officer who will be responsible for administering any grant that might be awarded. Each should sign the following declaration:

I confirm that I have read this application and criteria governing the award of a CICRA PhD Studentship and that, if granted, the work will be accommodated and administered in the Department/Institution.

(i) Signature of Head of Department (ii) Signature of Administrative Authority

Title: Director/Finance Officer/Bursar Registrar/Secretary (delete as appropriate):

Full Name of Above (printed) Full Name of Above (printed)

Institution Address Institution Address, telephone number, and fax number (of department) and email address

Date: Date:

Name, address, telephone number and email address of the officer who should be contacted regarding the administration of the grant, if awarded, if different from (ii) above

CICRA PhD Studentship Sept 2013