Updated 6/7/16

Valerie Horsley

Maxine F. Singer ’57 Associate Professor Departments of Molecular, Cellular and Developmental Biology and Dermatology Yale University Kline Biology Tower--Room 226 219 Prospect Street New Haven, CT 06520-8103 203-436-9126 [email protected] horsley.yale.edu/

Education and Work Experience

1994-1998 B.S. in Biology, Furman University, Greenville, SC 1998-2003 Ph.D. in Biochemistry, Cell and Dev. Biol., Emory University, Atlanta, GA Advisor: Grace Pavlath (thesis project: Cell fusion during mammalian myogenesis) 2003-2008 Postdoctoral Fellow, Rockefeller University, NY, NY Advisor: Dr. Elaine Fuchs (Mechanisms of stem cell lineage commitment/quiescence) 2009-2011 Assistant Professor, Yale University, Dept. of Molecular, Cellular and Developmental Biology 2011-present Maxine F. Singer ’57 Assistant Professor 2011-2014 Assistant Professor, Yale University, Dept. of Dermatology 2014-2016 Associate Professor, Yale University, Dept. of Molecular, Cellular and Developmental Biology (Primary Appointment) and Dermatology (Secondary Appointment) 2016-present Associate Professor with tenure, Yale University, Dept. of Molecular, Cellular and Developmental Biology (Primary Appointment) and Dermatology (Secondary Appointment)

Honors and Awards

1998 Elected to Phi Beta Kappa 2000-2002 NIH Training Grant in Biochemistry, Cell and Molecular Biology 2001-2003 Achievement Reward for College Scientists (ARCS) scholar 2003-2004 Rockefeller University Women and Science Fellowship 2004-2006 Damon Runyon Cancer Research Foundation Fellowship 2006 Robert Black Fellow of the Damon Runyon Cancer Research Foundation 2007 K99/R00 Pathway to Independence Award 2009 Blavatnick Award, NY Academy of Sciences 2010 Pew Scholar Award 2011 Maxine F. Singer ’57 Endowed Assistant Professor * Presented to the top female junior faculty member in the life sciences at Yale 2012 Presidential Early Career Award (PECASE) 2012 Rosalind Franklin Young Investigator Award, Genetics Society of America 2013 F1000 Faculty of the Year, Developmental Biology Updated 6/7/16

2016 Semi-finalist, HHMI Scholar Award

Publications

Total Publications: 37: total includes 10 review articles and 10 research articles as corresponding author (5/10 research articles were featured and/or provoked commentaries (denoted *)). h-index: 20.

Research Articles 1. B.B. Friday, V. Horsley, and G.K. Pavlath. (2000). Calcineurin is required for the initiation of skeletal muscle differentiation. J. Cell Biol. 149: 657-665. 2. V. Horsley, B.B. Friday, S. Matteson, K.M. Kegley, J. Gephart, and G.K. Pavlath. (2001). Regulation of the growth of multinucleated muscle cells by an NFATC2-dependent pathway. J. Cell Biol. 53: 329-38.

3. V. Horsley and G.K. Pavlath. (2003). Prostaglandin F2 induces skeletal muscle growth via an NFATC2 dependent pathway. J. Cell Biol. 161: 111-118. 4. V. Horsley, K. Jansen, S.T. Mills, and G.K. Pavlath. (2003). IL-4 acts as a myoblast recruitment factor during mammalian muscle growth. Cell. 113: 483-94. * Preview: Fusion with the fused: a new role for interleukin-4 in the building of muscle. Cell, 113: 422-423. 5. V. Horsley, D. O’Carroll, R. Tooze, Y. Ohinata, M.Saitou, T. Obukhanych, M. Nussenzweig, A. Tarakhovsky and E. Fuchs. (2006). Blimp1 defines a novel progenitor population that governs cellular input to the sebaceous gland. Cell. 126: 597-609. 6. V. Horsley, A. O. Aliprantis, L. Polak, L.H. Glimcher and E. Fuchs. (2008). NFATc1 balances quiescence and proliferation of skin stem cells. Cell. 132: 299-310. *Preview: A new role for an old friend: NFAT and stem cell quiescence. Cell Stem Cell. 2: 104-106. *Feature: Faculty of 1000. 7. E. Festa, J. Fretz, R. Berry, B. Schmidt, M. Rodeheffer, M. Horowitz and V. Horsley. (2011). Adipocyte lineage cells contribute to the skin stem cell niche. Cell. 146: 761-771. *Preview: Niche crosstalk: intercellular signals at the hair follicle. Cell. 146: 678-81. *Feature: Faculty of 1000. 8. A. F. Mertz, S. Banerjee, Y. Che, G. K. German, Y. Xu, C. Hyland, M. C. Marchetti, V. Horsley, and E. R. Dufresne (2012). Scaling of Traction Forces with the Size of Cohesive Cell Colonies. Phys. Rev. Lett. 108: 198101. 9. H. McGee, C. Booth, E.Festa, R. Flavell, and V. Horsley. (2012). Interleukin-22 mediates acute skin wound healing by promoting fibroblast function. J. Invest. Dermatol. 133: 1321-9. 10. A. F. Mertz, Y. Che, S. Banerjee, J. Goldstein, S. Revilla, C. Niessen, M. C. Marchetti, E. R. Dufresne and V. Horsley (2013). Cadherin-based intercellular adhesions organize epithelial cell-matrix forces. PNAS. 110: 842-7. *Feature: Faculty of 1000 11. B. Schmidt and V. Horsley. (2013). Intradermal adipocytes regulate fibroblast recruitment during skin wound healing. Development. 140: 1517-27. *Preview: Adipocytes and Wound Healing. Development 2013 140:e703. 12. A. Tadeu and V. Horsley. (2013). Notch signaling represses p63 expression in the developing surface ectoderm. Development. 140: 3777-3786. Updated 6/7/16

13. J. Goldstein, S. Fletcher, E. Roth, C. Wu, A. Chun, and V. Horsley. (2014). Calcineurin/Nfatc1 signaling controls skin stem cell quiescence through systemic hormone regulation by prolactin. Gene. Dev. 28: 983-994. *Feature: Faculty of 1000 14. P. Sun, M. Fallahi, K. Watanabe, B. Lee, C. Rheaume, D. Wu, V. Horsley, and X. Dai. (2014). Pygo2 regulates β-catenin-induced hair follicle stem cell/progenitor cell activation and skin hyperplasia. PNAS. 111: 10215-20. PMID: 24982158. 15. E. Jeffery, R. Berry, C. D. Church, S. Yu, B. A. Shook, V. Horsley, E. D. Rosen and M. Rodeheffer. (2014) Characterization of Cre Recombinase Models for the study of Adipose Tissue. Adipocyte. 3: 206-11. 16. A. Tadeu, S. Lin, L. Hou, L. Chung, M. Zhong, H. Zhoa and V. Horsley. (2015) Transcriptional profiling of keratinocyte specification in human embryonic stem cells. Plos One. 10: e0122493. 17. R. Stewart, A. Zubek, K. Rosowski, S. Schreiner, V. Horsley*, and M. King* (*co-corresponding author). (2015) LINC complexes support hair follicle integrity and intercellular adhesion. J. Cell Biol. 209: 403-18. *Preview: SUN protection for the skin. 209(3): 319. 18. K. Rosowski, A. Mertz, S. Norcross, E. Dufresne, and V. Horsley. (2015) Edges of human embryonic stem cell colonies display distinct mechanical properties and differentiation potential. Sci. Rep. 5: 14218. 19. J. Goldstein, E. Roth, N. Roberts, R. Zwick, S. Lin, S. Fletcher, A. Tadeu, C. Wu, A. Beck, C. Zeiss, M. Suarez-Farinas and V. Horsley. (2015) Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis. Mol. Biol. Cell. pii: mbc.E15-05-0282 (Epub ahead of print). 20. N. Roberts, B. Adams, N. I. McCarthy, R. M. Tooze, S. M. Parnell, G. Anderson, S. M. Kaech, and V. Horsley. (2016) Prdm1 regulates thymic epithelial function to prevent autoimmunity. JI. In preparation.

21. G. C. Rivera-Gonzalez, B.A. Shook, B. Holtrup, K. Bollag, M. S. Rodeheffer and V. Horsley. (2016) Adipocyte stem cell self-renewal is regulated by a Pdgfa/Akt signalling axis in the skin. Cell Stem Cell. In Revision.

22. B. Shook, E. Xiao, Y. Kumamoto, A. Iwasaki, and V. Horsley. (2016) CD301b+ monocyte /macrophage-derived cells are essential for effective skin wound healing. JID. In press.

23. R. Zwick, B. Holtrup, E. Roth, V. Seewaldt, S. Kwei, J. Wysolmerski, M. S. Rodeheffer, and V. Horsley. (2016) Defining the cellular mechanisms that control adipocyte repopulation during mammary gland involution. In preparation.

Reviews and Invited Chapters 1. V. Horsley and G.K. Pavlath. (2002). NFAT proteins: Ubiquitous regulators of cell differentiation and adaptation. J. Cell Biol. 156: 771-4. 2. G.K. Pavlath and V. Horsley. (2003). Cell fusion in skeletal muscle: Central role of NFATC2 in regulating muscle cell size. Cell Cycle. 2: 420-423. 3. V. Horsley and G.K. Pavlath. (2004). Making a Multinucleated Cell: Molecules that Regulate Myoblast Fusion. Cells, Tissues, and Organs. 176: 67-78. 4. C. Blanpain, V. Horsley, and E. Fuchs. (2007). Epithelial Stem Cells: Turning over New Leaves. Cell. 128: 445-458. Updated 6/7/16

5. V. Horsley and E. Fuchs. (2007). Reprogramming somatic cells to their embryonic state. HSFP Journal. 1: 89-93. 6. E. Fuchs and V. Horsley. (2008). More than one way to skin... Gene. Dev. 22: 976-985. 7. E. Fuchs and V. Horsley. (2011). Ferreting stem cells out of their niches. Nature Cell Biology. 13: 513-8. 8. V. Horsley. (2011). Upward bound: Follicular stem cell fate decisions. EMBO J. 30: 2986-7. 9. J. Goldstein and V. Horsley. (2012). Home sweet home: Skin stem cell niches. Cell. Mol. Life Sci. 69: 2573-82. 10. B. Schmidt and V. Horsley. (2012). Unraveling adipocyte-hair follicle communication. Exp. Dermatol. 21: 827-30. 11. V. Horsley. (2012). Split decisions: oesophageal progenitor cell behaviour. EMBO J. 31: 3653- 4. 12. C. Niemann and V. Horsley. (2012). Development and homeostasis of the sebaceous gland. Semin. Cell Dev. Biol. 23: 928-36. 13. G. Rivera, B. Shook and V. Horsley (2014). Adipocytes in Skin Health and Disease. Cold Spring Harb. Perspect. Med. 4. pii: a015271. 14. A. Tadeu and V. Horsley. (2014). Epithelial Stem Cells in Adult Skin. Curr. Top. Dev. Biol. 107: 109-31. 15. R. Driskell, C.A.B. Jahoda, C. Chuong, F. Watt, and V. Horsley. (2014). Defining Dermal Adipose Tissue. Exp. Dermatol. 23: 629-31. 16. N. Roberts and V. Horsley. (2014). Developing stratified epithelia: lessons from the epidermis and thymus. Wiley Interdiscip. Rev. Dev. Biol. 3: 389-402. 17. S. Ebmeier and V. Horsley. (2015). Origin of Fibrosing Cells in Systemic Sclerosis. Curr. Opin. Rheumatol. 27: 555-62. 18. C.M. Alexander, I. Kasza, C.E. Yen, S.B. Reeder, D. Hernando, R.L. Gallo, C.A. Jahoda, V. Horsley, O.A. MacDougald. (2015). Dermal White Adipose Tissue: A New Compartment of the Thermogenic Response. J. Lipid Res. pii: jlr.R062893 [Epub ahead of print].

Research Support

Pending Source: NIH Title: Mechanical Regulation of Epidermal Homeostasis Proposed dates: 04/01/16-03/31/21 Role: Co-PI (with Megan King)

Source: HHMI Scholar Award Competition Title: Stromal adipocytes in epithelial cell niches Proposed dates: 11/01/16-10/31/21 Role: PI

Current Source: NIH Title: Mechanisms that regulate skin wound healing Dates: 07/01/16-05/31/21 Role: PI Updated 6/7/16

Direct costs: $356,320 (annually)

Source: NIH R01 AR060295 Title: Extrinsic Regulation of Epidermal Homeostasis Dates: 09/30/2014 – 08/31/2017 Direct costs to date: $1,334,244.44; Indirect costs to date: $883,542.56; Total costs to date: $2,217,787.00 Role: PI

Source: CT Innovations CSCRF 12-SCB-YALE-01 Title: Generation of functional keratinocytes from hESCs Dates: 10/01/2012 — 09/30/2016 Direct costs to date: $600,000; Indirect costs to date: $150,000; Total costs to date: $750,000 Role: PI

Source: NIH P30AG021342; Pilot and Exploratory Studies Core of the Yale Claude D. Pepper Center Older Americans Independence Center Title: The role of dermal adipocytes in dysfunction of aged skin Dates: 07/01/2015 — 06/30/2016 Direct costs to date: $40,000; Indirect costs to date: $26,600; Total costs to date: $66,600 Role: PI

Source: Scleroderma Foundation Title: Functional analysis of the role of adipocytes in skin fibrosis Proposed dates: 04/01/16-3/31/18 Direct costs to date: $75,000 Role: PI

Source: Amway Inc. Gift to support our research Proposed date: 10/01/15 Direct costs to date: $25,000 Role: PI

Completed Source: Unilever Title: Examining adipocytes in human skin Dates: 7/01/2014 — 6/30/2015 Direct: $40,455 directs costs; Indirect costs: $26,903; Total cost: $67,358 Role: PI

Source: Schick Title: Determining how shaving influences inflammation Dates: 7/01/2014 — 6/30/2015 Direct: $5,821 directs costs; Indirect costs: $3,871; Total cost: $9,692 Role: PI

Source: NIH R00AR054775 Title: Mechanisms of sebaceous gland development Dates: 04/01/2009 — 03/30/2011 Direct costs: $469,491; Indirect costs: $307,516; Total costs: $777,007 Role: PI Updated 6/7/16

Source: CT Innovations CSCRF Title: Transcriptional Control of Keratinocyte Differentiation in Human ES Cells Dates: 6/01/2009 — 05/31/2011 Direct: $162,000 directs costs; Indirect costs: $38,000; Total cost: $200,000 Role: PI

Source: Pew Charitable Trusts Title: Transcriptional Regulation of Tissue Development and Homeostasis Dates: 07/01/2010 — 06/30/2015 Direct: $240,000 directs costs; Indirect costs: $ 0; Total cost: $240,000 Role: PI

Source: CT Innovations CSCRF (12-SCA-YALE-02) Title: Mechanical factors influencing the differentiation of human embryonic stem cells Dates: 10/15/2012 — 10/14/2014 Direct: $164,132 directs costs; Indirect costs: $35,868; Total cost: $200,000 Role: co-PI (with E. Dufresne)

Source: Gruber Foundation/Rosalind Franklin Young Investigator Award Dates: 10/01/2013 — 12/31/2015 Direct costs to date: $75,000; Indirect costs to date: $0; Total costs to date: $75,000 Role: PI

Public Presentations

2016 Seminars University of Colorado Denver (1/4/16) University of California Irvine (5/16)

Conferences Gordon Research Conference, Tissue Niches & Resident Stem Cells in Adult Epithelia, Invited Speaker (8/16) Gordon Research Conference, Signaling by Adhesion Receptors, Invited Speaker (6/16) Society of Investigative Dermatology, Speaker (5/16)

2015 Seminars Columbia University (1/14/15) University of Pennsylvania (2/5/15) Wesleyan University (4/30/15) Northwestern University (9/9/15) University of Cologne (10/28/15) Yale University, Endocrinology Program (11/15) Yale University, Immunobiology Department (12/15)

Conferences Skin Biology Symposium, Rockefeller University, Organizer and Invited Speaker (5/4/2015) Society for Investigative Dermatology, Blank Forum, Invited Speaker (5/7/2015) Gordon Research Conference, “Mammary Gland Biology”, Invited Speaker (6/10/2015) Gordon Research Conference, “Epithelial Keratinization and Differentiation”, Invited Speaker (7/15/2015) Updated 6/7/16

International Society of Hair Restoration Surgery Annual Meeting, Featured Guest Speaker (9/10/2015) Basel-Manchester Forum, Skin Repair & Regenerative Plastic Surgery, Keynote Speaker (10/30/15) Montagna Symposium of Skin Biology, Organizer and Invited Speaker (10/2015) National American Hair Society Meeting, Session Director and Invited Speaker (12/2015)

2014 Seminars HudsonAlpha Institute for Biotechnology (3/19/14) Emory University (4/15/14) University of California San Diego (6/14/14) Clemson University (10/23/14) Furman University (10/24/14)

Conferences CURE/BIOHAVEN Conference, Speaker/Panelist (10/21/14) CT Stem Cell Retreat, Invited Speaker ( NextGen Stem Cell Meeting, Invited Speaker (5/7/15) Society of Investigative Dermatology, Invited Speaker (5/15) Abbvie-Immunobiology conference, Invited Speaker (12/3/14)

2013 Seminars Duke University, Developmental & Stem Cell Biology Colloquium (1/16/2013) Yale University, Dermatology Department University of Cincinnati Children’s Hospital (9/4/13) Cornell University (9/27/13) Albert Einstein (10/14/13) Yale University, Vascular Biology Program (11/11/13) Rutgers Dermatology Symposium (11/16/13) Unilever Science Expo (12/11/13) Yale University, Cardiology Department (12/15/13)

Conferences Gordon Research Conference, “Epithelial Differentiation and Keratinization”, Invited Speaker (5/14/13) Gordon Research Seminar, “Epithelial Differentiation and Keratinization”, Invited Speaker (5/12/13) Keystone Symposium “Stem Cell Regulation in Homeostasis and Disease”, Invited Speaker (2/26/13)

2012 Seminars University of British Columbia, Biomedical Research Centre (4/13/12) Yale University, Dermatology Department (4/4/12) University of Georgia, Developmental Biology Symposium Speaker (10/12/12) Cambridge-Yale Symposium on Stem Cells (9/10/12) University of Dundee (9/12/12) John Hopkins University, Department of Biochemistry, School of Public Health (12/3/12)

Conferences Dermatogenetics, Invited Speaker (2/10/12) Society of Investigative Dermatology, PhD retreat, Keynote Speaker (5/9/12)

2011 Seminars Updated 6/7/16

Emory University, Chemical Biology Department (2/21/11) STEMCONN biannual meeting (3/22/11)

Conferences International Society for Stem Cell Research Annual Meeting, Speaker and Session Chair (6/16/11) Society for Investigative Dermatology Annual Meeting, State-of-the-Art Lecture and Session Chair (5/5/11) Gordon Research Conference, “Epithelial Differentiation and Keratinization”, Invited Speaker (7/4/11)

2010 Seminars Columbia University, Biology Department (2/2010) Stanford University, Department of Developmental Biology (6/14/10) Mt. Sinai, Department of Developmental Biology (9/30/10) Yale Stem Cell Retreat (10/22/10) University of Connecticut, School of Pharmacy (10/25/10) University of Iowa, Department of Molecular Physiology & Biophysics (11/10/10)

Conferences Connecticut Stem Cell Meeting, Invited Speaker (1/29/10) Keystone Symposia, “Stem Cell Differentiation and Dedifferentiation”, Invited Speaker (2/18/10) Society for Investigative Dermatology Annual Meeting, Speaker and Session Chair (5/6/10) International Society for Stem Cell Research, Annual Meeting, Invited Speaker (6/17/10)

2009 Seminars Mt Sinai, Department of Oncological Sciences (4/09)

Conferences National Hair Research Society, Featured Speaker (5/8/09)

2008 Seminars University of Michigan, Center for Stem Cell Research and Department of Dermatology Harvard University, Department of Stem Cell and Regenerative Medicine, Harvard Stem Cell Center Yale University, Department of Molecular, Cellular and Developmental Biology, Yale Stem Cell Center University of Pennsylvania, Cell and Developmental Biology

2006.2007 Seminars New York Skin Biology Club, New York, NY MGH Center for Regenerative Medicine, Harvard Stem Cell Institute University of Texas Southwestern, Department of Cell Biology Columbia University, Department of Genetics and Development John Hopkins, Molecular Biology and Genetics

Conferences Epithelial Stem Cell Workshop, Beatson Cancer Research Institute, Glasgow, Scotland, Invited Speaker

Teaching

Undergraduate Courses 2009-2014 Lecturer, MCDB205, “Cell Biology” Updated 6/7/16

2014-present Lecturer, BIOL102, “Foundations in Cell Biology”

Undergraduate Seminar Courses 2010-present Mentor, MCDB495, “Senior Research” 2010-2011 Session Leader, MCDB495, “Senior Research”

Graduate Courses 2011-2014 Course Director, MCDB901/GENE901/CBIO901, “Ethics in Science” 2010-2014 Founding Course Director, MCDB902/3, “Graduate Seminar Course” 2010-2011 Lecturer, MB&B520, “Boot Camp Biology” 2010 Instructor, MCDB900, “How to Write a Scientific Manuscript” 2013-2015 Instructor, “Responsible Conduct in Research Course” 2015 Instructor, Cell Biology, Shanghai Tech, Shanghai China

Outreach 2009-present “Science Experiments” –Children ages 4-9 I go to each of my daughter’s classrooms annually and do a presentation on science on topics ranging from matter to cell biology.

Mentoring at Yale University

Junior Faculty Mentoring Shirin Bahmanyar (formal). Murat Acar, Damon Clark and Joshua Gendron (informal).

Undergraduate Research Mentoring 2009-2011 Alexandra Graham, Summer Research, Senior Thesis 2009 Rachel O’Keefe, Summer Research 2010-2011 Sage Aronson, Summer Research 2010-2013 Yonglu Che, Summer and Annual Research 2010 Sarah Ballatori, Summer Research 2010 Martha Getachew, STARS program, Summer Research 2011-2014 Sean Fletcher, STARS program, Annual Research, Senior Thesis 2012 Stephen Revilla, Sackler Summer program 2012 Andrew Chun, Summer Research 2013 Sam Norcross, Sackler Summer program 2013-2015 Kevin Hochstrasser, Summer Research, Senior Thesis 2013 Adrian Fortin, Summer Research 2013-present Eve Roth, Summer and Annual Research 2013-2015 Erin Song, Summer and Annual Research, Senior Thesis 2013 Christine Wu, Summer Research 2014-present Christina Kim, STARS program, Summer Research 2014 Amanda Farrell, STARS program, Summer and Annual Research 2014 Mary Yates, Sackler Summer program 2015-present Stephen Le Breton, Summer and Annual Research 2015-present Bertie Geng, Summer and Annual Research 2015-present Katie Bollag, Summer and Annual Research

Graduate Research Mentoring in My Laboratory (Current position) 2010-2011 Heather McGee, MD/PhD* (Resident at UCSF) co-mentored with Richard Flavell 2010-2013 Aaron Mertz (Postdoctoral Fellow with Elaine Fuchs) co-mentored with Eric Dufresne Updated 6/7/16

2010-2014 Jill Goldstein (Postdoctoral fellow with Amy Wagers) 2011-2014 Barbara Schmidt (Editor with Genome Sciences) 2011-2015 Kathryn Rosowski (Postdoctoral Fellow) 2012-present Rachel Zwick 2014-present Gabriella Grisotti 2014-present Sarah Ebmeier

PhD Student Thesis Committees (Year Degree Awarded; Affiliation) * indicates served on PhD Qualifying Exam Sophia Gayle* 2013 Yale, Genetics Barbara Hirschman* 2013 Yale, Immunobiology Callen Hyland* 2013 Yale, MCDB Chanatip Metheetrairut* 2014 Yale, MCDB Su-Yi Tsai 2011 Mt. Sinai, Developmental Biology Devin Noblin* 2014 Yale, MCDB Ryan Berry* 2014 Yale, MCDB Minlee Kim* 2015 Yale, MCDB Jacob Musser* 2015 Yale, EE&B Rachel Sennett 2015 Mt. Sinai, Developmental Biology Rostislav Boltyanskiy 2015 Yale, Physics Patrick McMillen 2015 Yale, MCDB Victor Wong* 2016 Yale, MCDB Jonathan Levinsohn* current student Yale, Genetics Liz Min current student Yale, Cell Biology Jemilat Salami* current student Yale, MCDB Maggie Sledd* current student Yale, Cell Biology Young Lim* current student Yale, Genetics Carly Cox current student Yale, MCDB Young Kim current student Yale, Genetics

Postdoctoral Fellow Mentoring (Current position) 2009-2014 Ana Tadeu, PhD (Medical Writer; Porterhouse Medical, UK) 2011-2015 Natalie Roberts, PhD (Postdoctoral Fellow, Hayday Laboratory, UK) 2013-2015 Amanda Zubek, MD/PhD (Postdoctoral Fellow, Yale Dermatology) 2012-present Guillermo Rivera, PhD 2012-present Brett Shook, PhD 2013-2015 Samantha Lin, PhD (Lecturer, Yale MCDB Department)

Honors Awarded to Trainees 2011 Fundação para a Ciência e Tecnologia Postdoctoral Award (Ana Tadeu) 2014 Dermatology Foundation Research Fellowship (Amanda Zubek) 2014 Lo Family Fellowship (Rachel Zwick) 2014 F31 NRSA NICHD (Rachel Zwick) 2015 New York Stem Cell Foundation Fellowship (Brett Shook) 2015 American College of Surgeons Fellowship (Gabriella Grisotti) 2015 Dermatology Foundation Career Development Award (Amanda Zubek)

Activities and Service to Scientific Community

Consulting 2010-2014 Schick Hair follicle growth 2013-present Unilever Skin function Updated 6/7/16

Professional Societies International Society for Stem Cell Research Society for Investigative Dermatology

National Service 2010 Board of Scientific Counselors--Intramural Program of the National Institute of Arthritis and Musculoskeletal and Cutaneous Diseases 2012 National Institutes of Health Grant Reviewer, Arthritis, Connective Tissue and Skin study section (June), ad hoc 2013-present New York Stem Cell Foundation Postdoctoral Fellowship Reviewer 2013 National Institutes of Health Grant Reviewer, Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (June), ad hoc 2013-present International Society for Stem Cell Research Audit Committee 2014 National Institutes of Health Grant Reviewer, Musculoskeletal, Oral and Skin Sciences study section (July), ad hoc 2012-2014 Society of Investigative Dermatology, Education Committee 2015-2016 Society of Investigative Dermatology, Education Committee, Co-Chair 2015 National Institutes of Health Grant Reviewer, Intercellular Interactions study section (February), ad hoc 2016-present Editor, eLife 2016-present National Institutes of Health Grant Reviewer, Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee 2016-present National American Hair Research Society Board member 2017-present Medical and Scientific Review Committee, Dermatology Foundation 2016-present Chair of StemCONN 2017, Connecticut’s Stem Cell and Regenerative Medicine Conference

Journal Reviewer (ad hoc reviewer) Development; Developmental Biology; EMBO Journal; Journal of Cell Biology; Journal of Investigative Dermatology; Molecular and Cellular Biology; Nature; Nature Cell Biology; Nature communications; Proceedings of the National Academy of Sciences; Cell Stem Cell; Cell Reports; Elife, Science.

Service at Yale

Yale University Service 2009-2014 Founding Organizer, FAS Junior Faculty Group I established a group at Yale that initially included all of Science Jr. Faculty but eventually all of Yale. We met monthly to discuss topics of interest including mentoring, tenure and promotion, and strategies for success in teaching. 2009 Organizer, Yale Stem Cell Center Retreat Committee 2010-2011 Member, MCDG Graduate Admissions Committee 2011-present Member, Yale Stem Cell Center Advisory Committee 2010 Organizer, Yale University Childcare Initiative Megan King and I met with Stephanie Spangler and Francis Rosenbluth regularly to discuss expansion of childcare resources at Yale: resulted in establishment of The Nest at Yale for children ages 1-3 with a priority for Women Faculty in Science. 2011 Member, Yale University Childcare Task Force 2012 Organizer, Yale Jr. Faculty Retreat 2012-present Member, Lo Family Fellowship Selection Committee 2013-present Member, Women’s Faculty Forum Steering Committee Updated 6/7/16

2013 Yale College Executive Committee 2013-2015 Advisory Committee for Postdoctoral Affairs 2013 Discussion regarding facilities and Yale’s vision for STEM at Yale with President Salovey and Provost Polak 2014 FAS Senate Implementation Committee * One of two untenured ladder faculty on this committee, which established the format and rules for the inaugural senate for Yale University faculty in the Arts and Sciences. 2015 FAS Senate Election Committee, Co-Chair This committee implemented an electronic voting system for the election of the first 22 senators for the inaugural senate for Yale University faculty in the Arts and Sciences using the single transferable voting system. 2013-present Yale Biology Building (YBB) Building Committee Member  YBB Committee serves as the faculty advisory body for the design and construction of the ~$250 M Yale Biology Building to be completed in 2019. 2016-present Institutional Animal Care and Use Committee (IACUC) member

MCDB Department Service 2009-present Member, MCDB Seminar Committee 2009-2010 Organizer, Developmental Biology Training Grant Symposium 2009-2011 Chair, MCDB Retreat Committee 2010-present Chair, MCDB Animal Committee 2010-2014 Member, MCDB Graduate Affairs Committee 2011-present Founding Director, Science Hill Flow Cytometry Facility I was awarded an equipment grant from the NIH (official PI was Weimin Zhong due to my lack of R01) that established a Flow cytometry facility on Science Hill. 2013-present Chair, MCDB Communications Committee I completely revamped the MCDB website and update the news and content regularly. 2013-2015 Founding Organizer, MCDB Women in Science group I established a group in MCDB for women faculty and graduate students to build community and provide a forum for discussing issues related to gender and science. 2016-present Director of Graduate Admissions (DGA) 2015-2016 Member, MCDB Professional Climate and Diversity Committee 2016-present Chair, MCDB Professional Climate and Diversity Committee