Academic Affiliation: Emeritus Professor of Pharmaceutical and Medicinal Chemistry

Name: Mahmoud Abdel-Fattah Mostafa El-Gendy Academic affiliation: Emeritus Professor of Pharmaceutical and medicinal Chemistry Date of birth: July 16, 1938 Address: Home: Staff Members-Residences, University of Assiut, Assiut, Egypt. Tel: 002/088/2335767 Office: Faculty of Pharmacy, Assiut University , Assiut, Egypt. Tel: 002/088/2411296 ======EDUCATION: B. Pharmacy Cairo University (1962) M. Pharmacy Assiut University (1965) Pharm. Chemistry Ph.D. Pharm. Assiut University (1969) Pharm. Chemistry

EMPLOYMENT POSITIONS: Present: Emeritus Proffessor of Pharmaceutical Chemistry. Former: - Dean, Faculty of Pharmacy, University of Assiut (1983- 1986) -Vice Dean, Faculty of Pharmacy, University of Assiut (1979- 1983) - Associate Prof. Faculty of Pharmacy (1974- 1978) Pharm. Chemistry. - Assist. Prof. Faculty of Pharmacy (1969- 1974) Pharm. Chemistry. -Teaching Assist, (Demonstrator), (1962- 1969) - Chairman of Dept. of Pharm. Chem (1996- 1999)

FOREIGN TRAVELS: Country: Date Purpose of visit Norway 1972- 1974 Fellowship (Post doctoral) Sudan 1979- 1981 Visiting Professor U.S.A.(Boston) 1980 Congress on Pharmacy Education Bulgaria 1984 Visiting Professor. Canada (Montreal) 1985 Congress of FIP Finland (Helsinki) 1986 Congress of FIP Germany (Munich) 1989 Congress of FIP Yemen 1990-1995 Dean Faculty of Pharmacy Lebanon 2000 Conference Bulgaria 2005 Conference Turkey 2007 Conference

FORIGN LANGUAGES: English TEACHING EXPERIENCE: - Teaching Pharmaceutical Chemistry, Since 1969 in Assiut University. - Visiting Professor for teaching Pharmaceutical Chemistry, in KHARTOUM, MANSOURA and AL-AZHAR Universities of Sanaa University. (1990- 1995). - Research Advisor for Master degrees. - Research Advisor for Ph. D. Degrees.

OTHER ACTIVITIES: - Representative of Assiut University at the Supreme Council of the Egyptian Universities as: a) Councilor of the permanent Committee for Promotion of Associate professor in Pharmaceutical Chemistry b) Councilor of the Permanent Committee for Promotion of Associate Professor in Chemistry. c) Councilor of the Pharmaceutical Sientific Committee (1983- 986) d) Degrees equivalence Committe. (Formerly). e) Councilor of the Permanent Commette for Promation of Professors in Chemistry in Al-Azhar University. - Member of the Egyptian Pharmacy, Syndicate. - Member of the Egyptian Pharmaceutical Society. - Member of the Federation Internationale Pharmaceutique (FIP). - Editor of Bulletin of Pharm. Sciences, Assiut University. - Reviewer for the Egypt. J. Pharm. Sciences. - Reviewer for J. Pharm. Sciences, Al-Azhar University. - Principal Author and Coauthor of more than 44 Publications in the field of Pharmaceutical Chemistry. (List of Publications is enclosed).

LIST OF PUBLICATIONS 1- Synthesis of new sulphanilamido derivatives of p-aminosalicylic acid and isonicotinic acid hyrazides. M.A. Ibrahim and M.A. El-Gendy. J. Pharm. Sci. U.A.R., 7,33-42 (1966) 2- Synthesis of sulphanilamido benzaldehyde thiosemicarbazone derivatives. M.A. Ibrahim and M.A. El-Gendy. J. Pharm. Sci. U.A.R., 7,43-52 (1966).

3- Synthesis of certain new salicylsulphonylurea derivatives. A.A. Abou-Ouf, A.F. Youssef and M.A. El-Gendy. Acta Chimical Academiae Scientiarum Hungaricae 69 (1), pp. 81-86 (1971) 4- Synthesis of certain sulphonyl semicarbazide and thiosemicarbazide derivatives of salicylic acid having potential hypoglycemic activity M.A. El-Gendy and A.A. Abou-Ouf. Egypt J. Pharm. Sci., 14, No. 2, 197-203, 1973). 5- Mesoionic compounds (1). Design and synthesis of anhydro-5-hydroxy-2- phenyl-3-Methyl- thiazolium hydroxid derivatives. M.A. El-Gendy, M.A. Abd El-Kader, and M.A. El-Dawy. Bulletin of Faculty of Pharmacy, Cairo University, vol. XII No.1, (1973). 6- Mass spectral study of potential pharmacodynamic agents (II) Fragmentation pattern of certain anhydro-5-hydroxy-2-phenyl-3-methylthiazolium derivatives under electron impact. M.A. El-Gendy, M.A. El-Dawy, and M.A. Abd El-Kader. Bulletin of Faculty of Pharmacy, Cairo University, vol. XII No.1, (1973). 7- Potential broad spectrum anthelmintics (1). Derivatives of 3- Arylimidazo (2, 1-b) thiazole. M.A. El-Gendy, M.A. El-Dawy, G.M. El-Naggar. Proc. XIII Conf. Pharm. Sci., Cairo, Egypt (Feb. 1974). 8- Mass spectrometry of onium compounds. Ionization potentials in structure analysis of gaseous aminopyridine-1-oxides. Kjell Undheim, Mahmoud A.F. El-Gendy and Torgeir Hurum. Act Chemical Scandinavica B. 28 (1974) 743-749). 9- Synthesis of certain sulphonylurea derivatives of salicylic acid having potential hypoglycemic activity. M.A. El-Gendy, M.A. El-Dawy, and M.A. Abd El-Kader. Proc. XIII conf. Pharm. Sci., Cairo, Egypt, Feb. 1974). 10- Ionization Potential in structure analysis of isomeric nitrones, oxaziranes, ether, oximes and acid amides. Olav Thorstad , Kjell Undheim and Mahmoud a.f.El-gendy. Organic mass spectrometry, 1975, Vol. 10. pp 1155- 1159). 11-Mass spectrometry of onium compounds XXX-Ionization potentials structure analysis of sydnones. Kjell Undheim, MAHMOUD A.F. El-Gendy and Torgeir Hurum. Organic mass spectrometry, 1974, Vol. 9, pp. 1242-1244). 12- Borohydride reduction of benzodiazpinium salts. Nabil M.Omar, Adel F. Youssef and Mahmoud A. El-Gendy. Arch.Pharm. Chem. Sci., Ed, 3, 1975, 89-93). 13- Structure and psychotropic activity of a new tetrahydro benzodiazepine congener. N.M.Omar, A.F. Youssef, M.A. El-Gendy and M.M. Kassab. Canadian J. Pharm Sci., Vol. 11, No. .3, pp. 89-92, 1976). 14- UnsymmetricN,N-disubstituted anilines: Synthesis of a (N- methylaniline) acetamides. Adel F. Youssef, Hassan H.Farag, Mahmoud A.Abdel-Kader and Mahmoud A. El-Gendy. Indian Journal of Chemistry Vol. 14B, April 1976, pp. 279-281). 15- Mesoionic compounds (11). Design, synthesis, and mass spectral study of certain anhydro-5- hydroxy-2,3-diphenyl-thiazolium hydroxide derivatives. Mahmoud A. El-Gendy and Mohammed A. El-Dawy. gyptian J. Pharm. Sci., 17, No.1, pp. 35-42, (1976). 16- Analytical application of dimethoxydiquinone (VI). Spectrophotometric assay of sulphathiourea. Mohammed A. El-Dawy, M. Atef Abdel-Kader, M.A. El-Gendy and I.A. Ibrahim. Proc. XIV Conf. Pharm.Sci., Egypt, Cairo Dec. 1975). 17- Use of dimethoxydiquinone as an analytical reagent for the determination of isoniazide. Mohammed A. El-Dawy , M. Atef Abdel-Kader , M.A. El-Gendy and I.A. Ibrahim. Egypt. J., Pharm. Sci., 17 No. 2,pp 137- 144 (1976). 18- Analytical application of dimethoxydiquinone (V). Determination of ampicillin, hydralazine, and dihydralazine. Mohammed A. El-Dawy , M. Atef Abdel-Kader , M.A. El-Gendy and I.A. Ibrahim. Egypt. J. Pharm. Sci., 17, No. 1, pp. 71-82, (1976). 19- Fragmentation pattern of certain substituted naphthoquinone under electron impact. Ahmed S. Hamman and Mahmoud A.El-Gendy. Egypt. J. Pharm. Sci., 18, No. 4, pp. 367-376, 1977). 20- Arylsulphonyl N-L(+) threo-1-(p-nitrophenyl)-1,3-dihydroxy -isopropyl-oxamic acid hydrazides of potential hypoglycemic activity. A.M. Abdel Aleem and M.A. El-Gendy. Egypt. J. Pharm. Sci., 18, No.3 pp. 235-243, 1977). 21- Synthesis and hypoglycemic activity of new aryl N-D(-) and L (+) threo-1-(p-nitrophenyl)-1,3- dihydroxyisopropyl oxamic acid amides. A.M. Abdel Aleem and M.A. El-Gendy.Bull. of Faculty of Pharm. Cairo Univ., XVII-1,p. 93- 103, (1978). 22- Analysis and dissociation of certain acidic pharmaceutical compounds in n-butanol. Nawal A. El-Rabbat, Mahmoud A. El-Gendy and Kamla Emara. Bull. Pharm. Sci., Assiut Univ., Vol. 1, p. 115-131, 1978). 23- Design and synthesis of certain bridgehead nitrogenous heterocyclic compounds of potential antibacterial or antiparasitic activity. Am. Chem. Soc., Annual Meeting August 1984) Boston, USA 24- Antibacterial properties and SAR of 3-(6-bromo-2- imidazo[4,5-b] pyridinyl) propionic acid derivatives. A.F. Youssef, M.A. El-Gendy, N.A.E. Abou Taleb and S.H. Ahmed. Egypt. J. Pharm. Sci.,23, No. 1-4, pp 131- 139, 1983). 25- Synthesis and pharmacological evaluation of some novel oxanilamides. A.M. Abdel-Alim, M.A. El-Gendy, N.A. El-Koussi and H.I. El-Bitar. Arch. Pharm. Chem. Sci., Ed. 12, 8-16, 1984). 26- Synthesis of certain imidazo[2,1-b]benzothiazole derivatives as potent.antihypertensives (part 1). M.A. El-Gendy, N.M. Omar and A.A. El-Shorbagi XVIII Conference of Pharmaceutical Sciences (1984), Cairo, Feb. 24-27, F-06. Proc. XVIII Conf. Pharm. Sci., Cairo Egypt, Feb. 1984). 27- Synthesis of certain imidazo[2,1-b]benzothiazole derivatives as potent. antihypertensives (part 2). M.A. El-Gendy, N.M. Omar and A.A. El-Shorbagi XVIII Conference of Pharmaceutical Sciences (1984), Cairo, Feb. 24-27, F-06. 28- Synthesis and antibacterial activity of 3-p-subsitituedphenyl oxazolo-(3,2-a-)-benzimidazoles and [2,3-b] benzoxazolium perchlorates. M.A. El-Gendy and N.M. Omar. Proc. XVIII Conf. Pharm. Sci., Cairo Egypt, Feb. 1984). 29- Imidazo [2,1-b] benzothiazoes, synthesis and Anti-inflammatory activity of some imidazo [2,1-b]- benzothiazoes. A.A. El-Shorbagi, Shin-ichiro Sakai, M.A. El-Gendy, N.M. Omar and H.H. Farag. Chem. Pahrm. Bull, 36, 3760-4768 (1988) Japan. 30- Synthesis and analgesic activities of certain novel imidazo [4,5-b] pyridines. M.A. El-Gendy, H.H. Farag, J.Stedmani, G.S. El-Karamany. 49th International. Congress of Pharm. Sci., of F,I.P. 1989 (185) 31- Novel antineoplastic agents : Synthesis and reativities of certain N-(2-chloroethyl) and n-[2-(Bis- 2-chloroethyl) amino ethylpyridinium derivatives. M. A. El-Gendy, H.H. Farag. AM. Abdel-Alim and N. Abou-baker, 49th International. Congress of Pharm. Sci., of F,I.P. 1989 (185) 32- Synthesis and Preliminery Alkylating activities of certain new 1,4- Dinydropyridines, pyridinaim salts and 2,7- Diazabicyclo [4.1.0] Hept-3-enes. H.H. Farag, A.M. Abd el Alim, M.A. El-Gendy and N.A. El-Kossi, Bull Pharm. Sci. Assiut Univ., 16, part 2, 141- 150. 33- Quinazolinone Derivatives of Biological Interest V: Novel 4(3H)- Quinazolinones with sedative- hypnotic anticonvulsant and anti-inflammatory activities. Abdel-Alim M.Abdel-Alim, Abdel-Nasser A. El-Shorbagi, Mahmoud A. El-Gendy, Monir A. Amin, Hosny A.H. El-Shareif. Collect Czechoslovak Chem. Commun., 58, 1963 (1993). 34- Heptakes (2,6-dio-methyl)-β-cyclodextrin complexation, with glutethimide. Gamal A. El-Gendy and Mahmoud El-Gendy. Euro. J. Pharm. And Biopharm. Vol. 39 (6) 249- 254 (1993) 35- Synthesis and Biological activities of 6-bromo-2,3-DI-substituted -4)3H)-Quinazolinones. Abdel-Alim M.Abdel-Alim, Abdel-Nasser A. El-Shorbagi, Mahmoud A. El-Gendy, Monir A. Amin, Hosny A.H. El-Shareif.Indian J. Chem., Sect B, 33B, 260 (1994). 36- Effects of poeoniflorin derivatives of scopolamine Induced Amnesia using passive Avoidance Task in Mice; Structure-Activity Realtionship Atef A. Abdel-Hafez, Meselhy R. Meselhy, Norio Nakamura, Massao Hattori, Hiroshi Watanabe, Yukihisa Murakami, Mahmoud A. El- GENDY, Nadia M. Mahfouz and Tarek A. Mohamed Biol. Pharm. Bull. 21, 1174-1179 (1998) (JAPAN) 37 - Anticonvulsant Activity of Paeonimetabolin-I Aducts Obtained by Incubation of Paeoniflorin and Thiol compounds with Lactobacillus brevis. Atef A. Abdel-Hafez, Meselhy R. Meselhy, Norio Nakamura, Massao Hattori, Hiroshi Watanabe, Yukihisa Murakami, Mahmoud A. El- GENDY, Nadia M. Mahfouz and Tarek A. Mohamed. Biol. Pharm. Bull. 22, 491-494(1999) (JAPAN) 38- New Paeonilactone-A Adducts formed by Anaerobic Incubation of Paeoniflorin with Lactobacillus brevis in presence of Arylthiol. Atef A. Abdel-Hafez, Meselhy R. Meselhy, Norio Nakamura, Massao Hattori, Mahmoud A. El- GENDY, Nadia M. Mahfouz and Tarek A. Mohamed. Chem. Pharm. Bull.49 (7), 918-920 (2001) (JAPAN) 39- Novel 5-(2-Hydroxyphenyl)-3-substituted-2,3- dihydro-1,3,4- oxadiazole-2-thione derivatives: promising anticancer agents Ahmed S. Aboria, Hamdy M. Abdel-Rahman, Nadia M. Mahfouz and Mahmoud A. El-Gendy Bioorganic & Medicinal Chemistry, 14 ( 2006 ) 1236 – 1246 40- Synthesis and Three-dimensional Qualitative Structure Selectivity Relationship of 3.5- Disubstituted-2,4-Thiazolidine- dione Derivatives as COX-2 Inhibitors, Ahmed .M. Ali, Gamal S. El-Karammany, Nadia M. Mahfouz, Mahmoud A. El-Gendy, Awad A. Radwan and Mohammed A. Ismail. Arch. Pharm. Res. Vol.30, No10, 1180-1204, (2007) 41- Design, synthesis and molecular modeling study of acylated 1.2.4-triazole-3-acetates with potential anti-inflammatory activity. Ashraf M. Abdel-megeed, Hamdy M. Abdel-Rahman, Gamal- Eldien S. Alkaramany and Mahmoud A. El-Gendy, Eur.J. Med. Chem., 44, 117–123 (2009)