NAVBO's Vascular Biology Publication Alert

May 2014 Issue (papers published in April 2014)

NAVBO Members are highlighted in dark red

American Journal of Pathology William A Muller. How endothelial cells regulate transmigration of leukocytes in the inflammatory response. Am J Pathol., 184(4):886–896

Brandi H Gorden, Jong-Hyuk Kim, Aaron L Sarver, Aric M Frantz, Matthew Breen, Kerstin Lindblad-Toh, Timothy D O'Brien, Leslie C Sharkey, Jaime F Modiano, Erin B Dickerson. Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization. Am J Pathol., 184(4):985–995

Alessandra Decio, Giulia Taraboletti, Veronica Patton, Rachele Alzani, Patrizia Perego, Robert Fruscio, Juliane M Jürgensmeier, Raffaella Giavazzi, Dorina Belotti. Vascular endothelial growth factor C promotes ovarian carcinoma progression through paracrine and autocrine mechanisms. Am J Pathol., 184(4):1050–1061

Lisa Koodie, Hongyan Yuan, Jeffery A Pumper, Haidong Yu, Richard Charboneau, Sundaram Ramkrishnan, Sabita Roy. Morphine inhibits migration of tumor-infiltrating leukocytes and suppresses angiogenesis associated with tumor growth in mice. Am J Pathol., 184(4):1073–1084

Zhihong Yang, Haibo Wang, Yanchao Jiang, M Elizabeth Hartnett. VEGFA activates erythropoietin receptor and enhances VEGFR2-mediated pathological angiogenesis. Am J Pathol., 184(4):1230–1239

Biochemical Journal Christine Y. Chuang, Georg Degendorfer, Astrid Hammer, John M. Whitelock, Ernst Malle and Michael J. Davies. Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells. Biochem J., 459(2):313-22

Blood Yu Lan, Wenyan He, Zhuan Li, Yu Wang, Jun Wang, Jiao Gao, Weili Wang, Tao Cheng, Bing Liu, and Xiao Yang. Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation. Blood, 123:2161-2171

Qinyu Yao, Marie-Ange Renault, Candice Chapouly, Soizic Vandierdonck, Isabelle Belloc, Béatrice Jaspard-Vinassa, Jean-Marie Daniel-Lamazière, Muriel Laffargue, Aksam Merched, Claude Desgranges, and Alain-Pierre Gadeau. Sonic hedgehog mediates a novel pathway of PDGF-BB– dependent vessel maturation. Blood, 123:2429-2437

Stefan Liebner. Sonic hedgehog causes mural cells to jump ‘n’ run. Blood, 123:2285-2286

Pieter W. Kamphuisen and Hugo ten Cate. Cardiovascular risk in patients with hemophilia. Blood, 123:1297-1301

Cancer Cell Weiying Zhou, Miranda Y. Fong, Yongfen Min, George Somlo, Liang Liu, Melanie R. Palomares, Yang Yu, Amy Chow, Sean Timothy Francis O’Connor, Andrew R. Chin, Yun Yen, Yafan Wang, Eric G. Marcusson, Peiguo Chu, Jun Wu, Xiwei Wu, Arthur Xuejun Li, Zhuo Li, Hanlin Gao, Xiubao Ren, Mark P. Boldin, Pengnian Charles Lin, Shizhen Emily Wang. Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis. Cancer Cell, 25(4):547-548

Cancer Research Xing Wang, Zhiheng He, Tian Xia, Xiaofan Li, Deguang Liang, Xianzhi Lin, Hao Wen, and Ke Lan. Latency- Associated Nuclear Antigen of Kaposi Sarcoma–Associated Herpesvirus Promotes Angiogenesis through Targeting Notch Signaling Effector Hey1. Cancer Res., 74:2026-2037

Keri L. Schadler, Erika J. Crosby, Alice Yao Zhou, Dong Ha Bhang, Lior Braunstein, Kwan Hyuck Baek, Danielle Crawford, Alison Crawford, Jill Angelosanto, E. John Wherry, and Sandra Ryeom. Immunosurveillance by Antiangiogenesis: Tumor Growth Arrest by T Cell–Derived Thrombospondin-1. Cancer Res., 74:2171-2181 Clinical Science Carlos Maria Ferrario, Sarfaraz Ahmad, Sayaka Nagata, Stephen W Simington, Jasmina Varagic, Neal Kon, Louis Joseph Dell'italia. An evolving story of angiotensin-II-forming pathways in rodents and humans. Clin Sci (Lond)., 126(7):461–469.

Vaibhav B Patel, Nirmal Parajuli, Gavin Y Oudit. Role of angiotensin-converting enzyme 2 (ACE2) in diabetic cardiovascular complications. Clin Sci (Lond)., 126(7):471–482

Nicola E Clarke, Nikolai D Belyaev, Daniel W Lambert, Anthony J Turner. Epigenetic regulation of angiotensin- converting enzyme 2 (ACE2) by SIRT1 under conditions of cell energy stress. Clin Sci (Lond)., 126(7):507–516

Theophilus I Emeto, Joseph V Moxon, Erik Biros, Catherine M Rush, Paula Clancy, Lynn Woodward, Corey S Moran, Roby J Jose, Tam Nguyen, Philip J Walker, Jonathan Golledge. Urocortin 2 is associated with abdominal aortic aneurysm and mediates antiproliferative effects on vascular smooth muscle cells via corticotrophin releasing factor receptor 2. Clin Sci (Lond)., 126(7):517–527

Koen Verdonk, Willy Visser, Anton H Van Den Meiracker, A H Jan Danser. The renin-angiotensin-aldosterone system in preeclampsia: the delicate balance between good and bad. Clin Sci (Lond)., 126(8):537–544

Fiorentina Roviezzo, Antonella De Angelis, Luana De Gruttola, Antonio Bertolino, Nikol Sullo, Vincenzo Brancaleone, Mariarosaria Bucci, Raffaele De Palma, Konrad Urbanek, Bruno D'Agostino, Angela Ianaro, Raffaella Sorrentino, Giuseppe Cirino. Involvement of proteinase activated receptor-2 in the vascular response to sphingosine 1- phosphate. Clin Sci (Lond)., 126(8):545–556

Development Monica Y. Lee, Athanasia Skoura, Eon Joo Park, Shira Landskroner-Eiger, Levente Jozsef, Amelia K. Luciano, Takahisa Murata, Satish Pasula, Yunzhou Dong, Mohamed Bouaouina, David A. Calderwood, Shawn M. Ferguson, Pietro De Camilli, and William C. Sessa. Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development, 141:1465-1472

Rachel B. Reinert, Qing Cai, Ji-Young Hong, Jennifer L. Plank, Kristie Aamodt, Nripesh Prasad, Radhika Aramandla, Chunhua Dai, Shawn E. Levy, Ambra Pozzi, Patricia A. Labosky, Christopher V. E. Wright, Marcela Brissova, and Alvin C. Powers. Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development, 141:1480-1491

Aurelie Quillien, John C. Moore, Masahiro Shin, Arndt F. Siekmann, Tom Smith, Luyuan Pan, Cecilia B. Moens, Michael J. Parsons, and Nathan D. Lawson. Distinct Notch signaling outputs pattern the developing arterial system. Development, 141:1544-1552

Ariel B. Rydeen and Joshua S. Waxman. Cyp26 enzymes are required to balance the cardiac and vascular lineages within the anterior lateral plate mesoderm. Development, 141:1638-1648

Claudia Korn, Beate Scholz, Junhao Hu, Kshitij Srivastava, Jessica Wojtarowicz, Tabea Arnsperger, Ralf H. Adams, Michael Boutros, Hellmut G. Augustin, and Iris Augustin. Endothelial cell-derived non-canonical Wnt ligands control vascular pruning in angiogenesis. Development, 141:1757-1766 van Impel A, Zhao Z, Hermkens DM, Roukens MG, Fischer JC, Peterson-Maduro J, Duckers H, Ober EA, Ingham PW, Schulte-Merker S. Divergence of zebrafish and mouse lymphatic cell fate specification pathways. Development, 141(6):1228-38

Developmental Biology No vascular biology related publications this month

Developmental Cell Katie Bentley, Andrew Philippides, Erzsébet Ravasz Regan. Do Endothelial Cells Dream of Eclectic Shape? Developmental Cell, 29(2)146 - 158

Developmental Dynamics No vascular biology related publications this month

EMBO No vascular biology related publications this month EMBO Reports No vascular biology related publications this month

FASEB Journal Michael C. Hornburger, Bettina A. Mayer, Stefanie Leonhardt, Elisabeth A. Willer, Stefan Zahler, Andrea Beyerle, Krishnaraj Rajalingam, Angelika M. Vollmar, and Robert Fürst. A novel role for inhibitor of apoptosis (IAP) proteins as regulators of endothelial barrier function by mediating RhoA activation. FASEB J., 28:1938-1946

Renata Prunskaite-Hyyryläinen, Jingdong Shan, Antti Railo, Krista M. Heinonen, Ilkka Miinalainen, Wenying Yan, Bairong Shen, Claude Perreault, and Seppo J. Vainio. Wnt4, a pleiotropic signal for controlling cell polarity, basement membrane integrity, and antimüllerian hormone expression during oocyte maturation in the female follicle. FASEB J., 28:1568-1581

Genes and Development No vascular biology related publications this month

Journal of Biological Chemistry Vicky Chaar, Sandrine Laurance, Claudine Lapoumeroulie, Sylvie Cochet, Maria De Grandis, Yves Colin, Jacques Elion, Caroline Le Van Kim, and Wassim El Nemer. Hydroxycarbamide Decreases Sickle Reticulocyte Adhesion to Resting Endothelium by Inhibiting Endothelial Lutheran/Basal Cell Adhesion Molecule (Lu/BCAM) through Phosphodiesterase 4A Activation. J. Biol. Chem., 289:11512-11521

Andrew T. Hale, Hongmei Tian, Ejike Anih, Fernando O. Recio III, Mohammad A. Shatat, Trent Johnson, Xudong Liao, Diana L. Ramirez-Bergeron, Aaron Proweller, Masakazu Ishikawa, and Anne Hamik. Endothelial Krüppel- like Factor 4 Regulates Angiogenesis and the Notch Signaling Pathway. J. Biol. Chem., 289:12016-12028

Chia-Chi Chen, Li-Li Chen, Yu-Ting Hsu, Ko-Jiunn Liu, Chi-Shuan Fan, and Tze-Sing Huang. The Endothelin- Integrin Axis Is Involved in Macrophage-induced Breast Cancer Cell Chemotactic Interactions with Endothelial Cells. J. Biol. Chem., 289:10029-10044

Peter L. Voyvodic, Daniel Min, Robert Liu, Evan Williams, Vipul Chitalia, Andrew K. Dunn, and Aaron B. Baker. Loss of Syndecan-1 Induces a Pro-inflammatory Phenotype in Endothelial Cells with a Dysregulated Response to Atheroprotective Flow. J. Biol. Chem., 289:9547-9559

Fu Yi, Huan Wang, Qiang Chai, Xiaoli Wang, Win-Kuang Shen, Monte S. Willis, Hon-Chi Lee, and Tong Lu. Regulation of Large Conductance Ca2+-activated K+ (BK) Channel β1 Subunit Expression by Muscle RING Finger Protein 1 in Diabetic Vessels. J. Biol. Chem., 289:10853-10864

Sebastian Vogel, Madhumita Chatterjee, Katja Metzger, Oliver Borst, Tobias Geisler, Peter Seizer, Iris Müller, Andreas Mack, Susanne Schumann, Hans-Jörg Bühring, Florian Lang, Rüdiger V. Sorg, Harald Langer, and Meinrad Gawaz. Activated Platelets Interfere with Recruitment of Mesenchymal Stem Cells to Apoptotic Cardiac Cells via High Mobility Group Box 1/Toll-like Receptor 4-mediated Down-regulation of Hepatocyte Growth Factor Receptor MET. J. Biol. Chem., 289:11068-11082

Cuicui Chen, Zhubing Shi, Wenqing Zhang, Min Chen, Feng He, Zhenzhen Zhang, Yicui Wang, Miao Feng, Wenjia Wang, Yun Zhao, Jerry H. Brown, Shi Jiao, and Zhaocai Zhou. Striatins Contain a Noncanonical Coiled Coil That Binds Protein Phosphatase 2A A Subunit to Form a 2:2 Heterotetrameric Core of Striatin-interacting Phosphatase and Kinase (STRIPAK) Complex. J. Biol. Chem., 289:9651-9661

Jasmin Zimmermann, Lorenz Latta, Andreas Beck, Petra Leidinger, Claudia Fecher-Trost, Gabriel Schlenstedt, Eckart Meese, Ulrich Wissenbach, and Veit Flockerzi. Trans-activation Response (TAR) RNA-binding Protein 2 Is a Novel Modulator of Transient Receptor Potential Canonical 4 (TRPC4) Protein. J. Biol. Chem., 289:9766-9780

Anna Sobolewska-Stawiarz, Nicole G. H. Leferink, Karl Fisher, Derren J. Heyes, Sam Hay, Stephen E. J. Rigby, and Nigel S. Scrutton. Energy Landscapes and Catalysis in Nitric-oxide Synthase. J. Biol. Chem., 289:11725-11738

Joseph A. DiDonato, Kulwant Aulak, Ying Huang, Matthew Wagner, Gary Gerstenecker, Celalettin Topbas, Valentin Gogonea, Anthony J. DiDonato, W. H. Wilson Tang, Ryan A. Mehl, Paul L. Fox, Edward F. Plow, Jonathan D. Smith, Edward A. Fisher, and Stanley L. Hazen. Site-specific Nitration of Apolipoprotein A-I at Tyrosine 166 Is Both Abundant within Human Atherosclerotic Plaque and Dysfunctional. J. Biol. Chem., 289:10276-10292 Raffaele Lopreiato, Marta Giacomello, and Ernesto Carafoli. The Plasma Membrane Calcium Pump: New Ways to Look at an Old Enzyme. J. Biol. Chem., 289:10261-10268

Journal of Cell Biology Jennifer L. Bays, Xiao Peng, Catlin E. Tolbert, Christophe Guilluy, Ashley E. Angell, Yuan Pan, Richard Superfine, Keith Burridge, and Kris A. DeMali. Vinculin phosphorylation differentially regulates mechanotransduction at cell–cell and cell–matrix adhesions. J. Cell Biology, 205:251-263

Perrine Pinon, Jenita Pärssinen, Patricia Vazquez, Michael Bachmann, Rolle Rahikainen, Marie-Claude Jacquier, Latifeh Azizi, Juha A. Määttä, Martin Bastmeyer, Vesa P. Hytönen, and Bernhard Wehrle-Haller. Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing. J. Cell Biology, 205:265-281

Journal of Cell Science Fang Fang, Scott M. Wasserman, Jesus Torres-Vazquez, Brant Weinstein, Feng Cao, Zongjin Li, Kitchener D. Wilson, Wen Yue, Joseph C. Wu, Xiaoyan Xie, and Xuetao Pei. The role of Hath6, a newly identified shear-stress- responsive transcription factor, in endothelial cell differentiation and function. J Cell Sci., 127:1428-1440

Alexandra E. German, Tadanori Mammoto, Elisabeth Jiang, Donald E. Ingber, and Akiko Mammoto. Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression. J Cell Sci., 127:1672-1683

Richard S. Beard, Jr, Ricci J. Haines, Kevin Y. Wu, Jason J. Reynolds, Stephanie M. Davis, John E. Elliott, Nikolay L. Malinin, Victor Chatterjee, Byeong J. Cha, Mack H. Wu, and Sarah Y. Yuan. Non-muscle Mlck is required for β- catenin- and FoxO1-dependent downregulation of Cldn5 in IL-1β-mediated barrier dysfunction in brain endothelial cells. J Cell Sci., 127:1840-1853

Journal of Clinical Investigation Jing Li, Kyungho Kim, Eunsil Hahm, Robert Molokie, Nissim Hay, Victor R. Gordeuk, Xiaoping Du, Jaehyung Cho. Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation. J Clin Invest., 124(4):1483–1496

John G. Facciponte, Stefano Ugel, Francesco De Sanctis, Chunsheng Li, Liping Wang, Gautham Nair, Sandy Sehgal, Arjun Raj, Efthymia Matthaiou, George Coukos, Andrea Facciabene. Tumor endothelial marker 1–specific DNA vaccination targets tumor vasculature. J Clin Invest., 124(4):1497–1511

Ilse Daehn, Gabriella Casalena, Taoran Zhang, Shaolin Shi, Franz Fenninger, Nicholas Barasch, Liping Yu, Vivette D’Agati, Detlef Schlondorff, Wilhelm Kriz, Borje Haraldsson, Erwin P. Bottinger. Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis. J Clin Invest., 124(4):1608– 1621

Matthew W. Parker, Daniel Rossi, Mark Peterson, Karen Smith, Kristina Sikström, Eric S. White, John E. Connett, Craig A. Henke, Ola Larsson, Peter B. Bitterman. Fibrotic extracellular matrix activates a profibrotic positive feedback loop. J Clin Invest., 124(4):1622–1635

Maggie P.Y. Lam, Ding Wang, Edward Lau, David A. Liem, Allen K. Kim, Dominic C.M. Ng, Xiangbo Liang, Brian J. Bleakley, Chenguang Liu, Jason D. Tabaraki, Martin Cadeiras, Yibin Wang, Mario C. Deng, Peipei Ping. Protein kinetic signatures of the remodeling heart following isoproterenol stimulation. J Clin Invest., 124(4):1734– 1744

Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ. Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment. J Clin Invest., 124(1):425-36

Journal of Experimental Medicine Benjamin D.S. Clarkson, Changying Ling, Yejie Shi, Melissa G. Harris, Aditya Rayasam, Dandan Sun, M. Shahriar Salamat, Vijay Kuchroo, John D. Lambris, Matyas Sandor, and Zsuzsanna Fabry . T cell–derived interleukin (IL)-21 promotes brain injury following stroke in mice. J. Exp. Medicine, 211(4):595-604

Journal of Lipid Research Rocco Romagnuolo, Santica M. Marcovina, Michael B. Boffa, and Marlys L. Koschinsky. Inhibition of plasminogen activation by apo(a): role of carboxyl-terminal lysines and identification of inhibitory domains in apo(a). J. Lipid Res., 55(4):625-634

Yan-Wei Hu, Jun-Yao Yang, Xin Ma, Zhi-Ping Chen, Ya-Rong Hu, Jia-Yi Zhao, Shu-Fen Li, Yu-Rong Qiu, Jing-Bo Lu, Yan-Chao Wang, Ji-Juan Gao, Yan-Hua Sha, Lei Zheng, and Qian Wang . A lincRNA-DYNLRB2-2/GPR119/GLP- 1R/ABCA1-dependent signal transduction pathway is essential for the regulation of cholesterol homeostasis. J. Lipid Res., 55(4):681-697

Molecular and Cellular Biology No vascular biology related publications this month

Molecular Biology of the Cell Maria Luisa Guzmán-Hernández, Gael Potter, Kristóf Egervári, Jozsef Z Kiss, Tamas Balla. Secretion of VEGF-165 has unique characteristics, including shedding from the plasma membrane. Mol Biol Cell., 25(7):1061–1072

Nature Joel A Spencer, Francesca Ferraro, Emmanuel Roussakis, Alyssa Klein, Juwell Wu, Judith M Runnels, Walid Zaher, Luke J Mortensen, Clemens Alt, Raphaël Turcotte, Rushdia Yusuf, Daniel Côté, Sergei A Vinogradov, David T Scadden, Charles P Lin. Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature, 508(7495):269–273

Daniel M Greif and Anne Eichmann. Vascular biology: Brain vessels squeezed to death. Nature, 508(7494):50– 51

Catherine N Hall, Clare Reynell, Bodil Gesslein, Nicola B Hamilton, Anusha Mishra, Brad A Sutherland, Fergus M O'Farrell, Alastair M Buchan, Martin Lauritzen, David Attwell. Capillary pericytes regulate cerebral blood flow in health and disease. Nature, 508(7494):55–60

Nature Cell Biology Elisabetta Dejana, Maria Grazia Lampugnani. Differential adhesion drives angiogenesis. Nat Cell Biol., 16(4):305–306

Katie Bentley, Claudio Areias Franco, Andrew Philippides, Raquel Blanco, Martina Dierkes, Véronique Gebala, Fabio Stanchi, Martin Jones, Irene M Aspalter, Guiseppe Cagna, Simone Weström, Lena Claesson-Welsh, Dietmar Vestweber, Holger Gerhardt. The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis. Nat Cell Biol., 16(4):309–321

Nature Genetics Sam Behjati, Patrick S Tarpey, Helen Sheldon, Inigo Martincorena, Peter Van Loo, Gunes Gundem, David C Wedge, Manasa Ramakrishna, Susanna L Cooke, Nischalan Pillay, Hans Kristian M Vollan, Elli Papaemmanuil, Hans Koss, Tom D Bunney, Claire Hardy, Olivia R Joseph, Sancha Martin, Laura Mudie, Adam Butler, Jon W Teague, Meena Patil, Graham Steers, Yu Cao, Curtis Gumbs, Davis Ingram, Alexander J Lazar, Latasha Little, Harshad Mahadeshwar, Alexei Protopopov, Ghadah A Al Sannaa, Sahil Seth, Xingzhi Song, Jiabin Tang, Jianhua Zhang, Vinod Ravi, Keila E Torres, Bhavisha Khatri, Dina Halai, Ioannis Roxanis, Daniel Baumhoer, Roberto Tirabosco, M Fernanda Amary, Chris Boshoff, Ultan McDermott, Matilda Katan, Michael R Stratton, P Andrew Futreal, Adrienne M Flanagan, Adrian Harris, Peter J Campbell. Recurrent PTPRB and PLCG1 mutations in angiosarcoma. Nat Genet., 46(4):376–379

Nature Medicine Andreas Schober, Maliheh Nazari-Jahantigh, Yuanyuan Wei, Kiril Bidzhekov, Felix Gremse, Jochen Grommes, Remco T A Megens, Kathrin Heyll, Heidi Noels, Michael Hristov, Shusheng Wang, Fabian Kiessling, Eric N Olson, Christian Weber. MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1. Nat Med., 20(4):368–376

PNAS Mark Juhas, George C. Engelmayr, Jr., Andrew N. Fontanella, Gregory M. Palmer, and Nenad Bursac. Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo. PNAS, 111(15):5508-5513

Pei-Yu Chen, Lingfeng Qin, Zhen W. Zhuang, George Tellides, Irit Lax, Joseph Schlessinger, and Michael Simons. The docking protein FRS2α is a critical regulator of VEGF receptors signaling. PNAS, 111(15):5514-5519 Vincent S. Tagliabracci, James L. Engel, Sandra E. Wiley, Junyu Xiao, David J. Gonzalez, Hitesh Nidumanda Appaiah, Antonius Koller, Victor Nizet, Kenneth E. White, and Jack E. Dixon. Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. PNAS, 111(15):5520-5525

Natalia I. Dmitrieva and Maurice B. Burg. Secretion of von Willebrand factor by endothelial cells links sodium to hypercoagulability and thrombosis. PNAS, 111(17):6485-6490

Science No vascular biology related publications this month

Member Submissions Sun X, Sit A, Feinberg MW. Role of miR-181 family in regulating vascular inflammation and immunity. Trends Cardiovasc Med., 24(3):105-112

Pfaltzgraff ER, Shelton EL, Galindo CL, Nelms BL, Hooper CW, Poole SD, Labosky PA, Bader DM, Reese J. Embryonic domains of the aorta derived from diverse origins exhibit distinct properties that converge into a common phenotype in the adult. J Mol Cell Cardiol., 69:88-96

Cheung C, Bernardo AS, Pedersen RA, Sinha S. Directed differentiation of embryonic origin-specific vascular smooth muscle subtypes from human pluripotent stem cells. Nature Protocols, 9(4):929-38

Zhongkui Hong, Zhe Sun, Min Li, Zhaohui Li, Filiz Bunyak, Ilker Ersoy, Jerome P. Trzeciakowski, Marius Catalin Staiculescu, Minshan Jin, Luis Martinez-Lemus, Michael A. Hill, Kannappan Palaniappan and Gerald A. Meininger. Vasoactive agonists exert dynamic and coordinated effects on vascular smooth muscle cell elasticity, cytoskeletal remodelling and adhesion. J Physiol., 592(6):1249–1266

Allahverdian S, Chehroudi AC, McManus BM, Abraham T, Francis GA. Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis. Circulation, 129: 1551-1559

Zhou Q., Yang D., Ombrello A.K., Zavialov A.V., Toro C., Zavialov A.V., Stone D.L., Chae J.J., Rosenzweig S.D., Bishop K., Barron K.S., Kuehn H.S., Hoffmann P., Negro A., Tsai W.L., Cowen E.W., Pei W., Milner J.D., Silvin C., Heller T., Chin D.T., Patronas N.J., Barber J.S., Lee C.C., Wood G.M., Ling A., Kelly S.J., Kleiner D.E., Mullikin J.C., Ganson N.J., Kong H.H., Hambleton S., Candotti F., Quezado M.M., Calvo K.R., Alao H., Barham B.K., Jones A., Meschia J.F., Worrall B.B., Kasner S.E., Rich S.S., Goldbach-Mansky R., Abinun M., Chalom E., Gotte A.C., Punaro M., Pascual V., Verbsky J.W., Torgerson T.R., Singer N.G., Gershon T.R., Ozen S., Karadag O., Fleisher T.A., Remmers E.F., Burgess S.M., Moir S.L., Gadina M., Sood R., Hershfield M.S., Boehm M., Kastner D.L., Aksentijevich I. Early-onset stroke and vasculopathy associated with mutations in ADA2. New England Journal of Medicine, 370(10): 911-20

Cooley B.C., Nevado J., Mellad J., Yang D., St. Hilaire C., Negro A., Fang F., Chen G., San H., Walts A.D., Schwartzbeck R.L., Taylor B., Lanzer J.D., Wragg A., Elagha A., Beltran L.E., Berry C., Feil R., Virmani R., Ladich E., Kovacic J.C., Boehm M. TGF-β Signaling Mediates Endothelial-to-Mesenchymal Transition (EndMT) During Vein Graft Remodeling. Science Translational Medicine, 6(227): 227ra34

Nijmeh H, Balasubramaniam V, Burns N, Ahmad A, Stenmark KR, Gerasimovskaya EV. High proliferative potential endothelial colony-forming cells contribute to hypoxia-induced pulmonary artery vasa vasorum neovascularization. Am J Physiol Lung Cell Mol Physiol., 306(7):L661-71

Ruth-Maria Korth. Women with overweight, mixed hyperlipidemia, intolerance to glucose and diastolic hypertension. Health, 6(5):454-467

Geevarghese A, Herman IM. Pericyte-endothelial crosstalk: implications and opportunities for advanced cellular therapies. Transl Res., 163(4):296-306

Patrick Allen, Kyu-Tae Kang and Joyce Bischoff. Rapid onset of perfused blood vessels after implantation of ECFCs and MPCs in collagen, PuraMatrix and fibrin provisional matrices. J Tissue Eng Regen Med