Oregon Health and Science University Portland, OR

Eleonora Juarez [email protected]

EDUCATION

Oregon Health and Science University Portland, OR Graduate Studies - Program in Molecular and Medical Genetics

The University of Texas at Brownsville Brownsville, TX Bachelors of Science in Biology

The University of Texas at Austin Austin, TX Candidate for Bachelors of Arts in Biology

Texas State Certified Nurse Assistant Brownsville, TX - May 2005

RESEARCH EXPERIENCE

Graduate Student Research Assistant at Oregon Health and Science University School of Medicine Amanda McCollough’s Laboratory Portland, OR - Spring 2013

The Role of Chromatin Remodeling in Cellular Processing of Formaldehyde-Induced DNA Damage: Formaldehyde is one of the most well studied reactive aldehydes and is characterized as a potent DNA-protein crosslinking (DPC) agent and carcinogen. It is present in both environmental and occupational toxicants, and has been shown to have detrimental effects on human health via both acute and chronic exposures. DPCs have previously been shown to interfere with genome maintenance through disruption of replication, recombination, and transcription. I seek to elucidate the importance of chromatin remodeling for repair of DNA- protein crosslinks (DPCs) induced by formaldehyde exposure. I hypothesize that increased chromatin remodeling will be necessary for the efficient repair of DPCs, likely due to their inherent and unique bulky and biochemical structure.

Biological Sciences Summer Research Program at Johns Hopkins School of Medicine Dr. Fred Bunz’s Laboratory Baltimore, MD - Summer 2010

Radiation Oncology Department: We were interested in the specific role that deubiquitinating enzymes play in DNA damage repair and subsequent cell cycle progression in cancer cells treated with ionizing radiation (IR), a frequently employed anticancer agent. Our immediate goal, and my particular role, was to create an USP9x knockout cell line that would facilitate further experimentation and investigation into the role of USP9x in cell cycle regulation after DNA damage.

5 Eleonora Juarez Equity Summer Research Program at Oregon Health and Science University Dr. Andrey Ryabinin’s Laboratory Portland, OR - Summer 2009

Behavioral Neuroscience Department: Performed experiments on mice to further understand the role of ghrelin (a hormone secreted in the stomach) in ethanol consumption. The results could lead to the development of therapies for alcoholism in the future.

Minority Biomedical Research Support Research Initiative for Scientific Enhancement MBRS-RISE Dr. Michael W. Lehker’s Laboratory Brownsville, TX – December 2011

Using Trichomonas vaginalis, we are deriving the minimal requirements of a eukaryotic iron- acquisition and utilization system to eventually reconstruct the evolutionary history of such systems in higher eukaryotes.

PROFESSIONAL MEETING PRESENTATIONS

Annual MBRS-RISE Orientation 2010 Research Poster Presenter

Johns Hopkins Summer Internship: Basic Sciences 2010 Research Symposium Research Poster Presenter

Johns Hopkins Summer 2010 Department of Radiation Oncology Presentation Oral Summer Project Presenter

UTB/TSC Research Symposium 2010 Research Poster Presenter

Behavior, Biology, and Chemistry Translational Research in Addiction 2010 Research Poster Presenter

SACNAS National Conference 2009 Research Poster Presenter

Annual MBRS-RISE 2009 Research Poster Presenter

Equity Summer Research Symposium 2009 Research Oral Presenter

5 Eleonora Juarez PUBLISHED MANUSCRIPTS/ABSTRACTS

INVESTIGATION OF USP9x AS A TARGET FOR RADIOSENSITIZING CANCER CELLS Eleonora Juarez¹, Dennis Harris², and Fred Bunz² 1 Department of Biology, University of Texas at Brownsville, Brownsville, TX 78520 2 Department of Radiation Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205 SACNAS: 2010

THE INVOLVEMENT OF GHRELIN IN ETHANOL INDUCED EXPRESSION OF C-FOS IN THE PIIIU OF MICE Eleonora Juarez¹, Simranjit Kaur², and Andrey E. Ryabinin² Department of Behavioral Neuroscience Oregon Health and Science University, Portland, Oregon² University of Texas at Brownsville, Brownsville, Texas¹ SACNAS: 2009

ACCOMPLISHMENTS AND HONORS

NIH Ruth L Kirschstein T32 Training Grant 2012

CSMT Talent Scholarship Recipient 2010

Annual Meeting: Society for the Advancement of Chicanos and 2010 Native Americans in the Sciences (SACNAS): Award for Outstanding Poster Presentation: Cancer Biology

Dean’s List: College of Science, Math and Technology 2010

Dean’s List: College of Liberal Arts 2010

Acknowledgement in Publication: 2010 Ghrelin Receptor Antagonism Decreases Alcohol Consumption and Activation of Perioculomotor Urocortin-Containing Neurons published in Alcoholism: Clinical and Experimental Research Journal

2nd Place in UTB/TSC Research Symposium in Biological Sciences 2010

MBRS-RISE Scholar 2009

TSC Trustee Scholarship 2009

Smart GT Grant Recipient 2009

5 Eleonora Juarez ACTIVITIES AND ORGANIZATIONS

OHSU Peer Mentor 2012

8th Annual Biosafety Workshop 2009

Society for the Advancement of Chicanos and 2010 Native Americans in the Sciences (SACNAS) Vice-President

American Society for Biochemistry and Molecular Biology (ASBMB) 2009-Present Undergraduate Student Member

American Association for Cancer Research (AACR) 2009-Present Undergraduate Student Member

Society for the Advancement of Chicanos and 2010 Native Americans in the Sciences (SACNAS) Secretary

F.U.N.K 2009 Functional Neuroimaging Journal Club - OHSU

MBRS-RISE 2009-Present Research Initiative for Scientific Enhancement – UT Brownsville 7th Annual Biosafety Workshop 2009

MAC 2008-2009 Medical Academic Coalition – UT Brownsville

Humanities Weekend Workshops 2008- Present

Hispanic Health Weekly Seminar Series at School of Public Health 2008- Present

6th Annual Biosafety Workshop 2008

Alpha Psi Sigma 2006- 2007 Pre- Medical Co-Ed Fraternity – UT Austin

NHS 2005- 2007 National Hispanic Scholars – UT Austin

MAHP 2005- 2007 Mexican American in Health Professions – UT Austin

5 Eleonora Juarez COMMUNITY SERVICE AND VOLUNTEER ACTIVITIES . Survival Assay Meals on Wheels Portland, OR . Immunofluorescence Volunteer November 2012 - Present . Mammalian Cell Culture South Padre Island Beach Clean Up . Yeast Culture South Padre Island, TX Volunteer . PCR April 2010 . Protein Stitching East Brownsville Little Miss Kickball . Molecular cloning Brownsville, TX Junior Girls Division Coach . Primer design February 2008 – May 2010

WORK EXPERIENCE

Pronto Auto Insurance Brownsville, TX Reporting Specialist February 2010 – September 2010 Provided monthly and annual reports to top management of sales, claims, and productivity of the company as whole. Gave detailed information regarding regional improvements and future expansion direction and feasibility according to current and projected markets.

Wells Fargo Brownsville, TX Teller May 10 – August 2008 Learned how to handle all Wells Fargo transactions on the teller line as well as sell necessary products to our customers. Performed transactions in a high volume branch in lobby, drive-thru, and commercial setting.

Gazpachos Mediterranean Bistro Brownsville, TX Server June 2007 - December 2007 Tend to customer needs in an upscale setting while maintaining a professional environment.

Public Employees Credit Union Austin, TX Teller February 2006 - December 2006 Carry out various transactions such as withdrawals, loan payments, deposits, etc. Worked in a moderately busy drive-thru Certified in details of the Bank Secrecy Act and all other confidentiality matters.

Johnny Carinos Brownsville, TX Host/ Server May 2004- Current (Seasonal) Workload of an average of 20 hours per week in a very busy family restaurant Trained 8-9 hostesses Received very good evaluation every six months for excellent customer service skills

SKILLS

Laboratory: . Microbe Cell Culture

5 Eleonora Juarez . Medium preparation . Use of Hemocytometer . Slicing in Cryostat . Immunohistochemistry . Fluorescent Microscopy . Protocol Preparation . Cell Adherence Assays . MTT Assay . Dot Blot . Electrophoresis

Clerical: EKG, vital signs, interview patients, HIPPA training, patient filing

Computer: Microsoft Word, Excel, Power Point, Access, CLC Sequence Viewer

Languages: Spanish; Native Fluency, English

REFERENCES

Oregon Health and Science University Dr. Amanda McCullough, Ph.D., Molecular and Medical Genetics Associate Professor Phone: (503)-494-9958 Email: [email protected]

University of Texas at Brownsville, Biology Department Dr. Michael Lehker, Ph.D., Biology Department Chair Phone: (956) 882-7960 Email: Michael . Lehker @ utb .edu

Johns Hopkins School of Medicine Dr. Fred Bunz, MD/Ph.D., Associate Professor, Radiation Oncology Phone: (410)-502-7941 Email: [email protected]

Oregon Health and Science University Dr. Andrey E. Ryabinin, Ph.D., Professor, Behavioral Neuroscience Phone: (503) 494-2060 Email: ryabinin @ ohsu .edu

University of Texas at Brownsville Dr. Eldon Nelson, Ph.D., Dean of School of Health, MBRS-RISE Director Phone: (956)882-5000 Email: [email protected]

5 Eleonora Juarez