AP Biology: Immune System Webquest s1

Name: ______Date: _____ Period: ____ 1

Human Physiology: Immune System WebQuest

Go to this website:

Watch the first 2:40 of the following video that shows gives an overview of how the body protects itself from microbes and explains how the first and second lines of defense work.( NOTE: You need to have YouTube open before clicking on this link at school.) http://www.youtube.com/watch?v=IWMJIMzsEMg

1. What are the body’s three defenses? How do they differ from each other?

2. How do the skin, sweat glands, mucus membranes, and acids in the stomach protect the body? To what level of defense do these belong?

3. What are three nonspecific internal defenses?

Watch the following video about natural killer cells. NOTE: You need to have YouTube open before clicking on this link at school. http://www.youtube.com/watch?v=HNP1EAYLhOs

4. What are natural killer cells? What kinds of cells do they attack? How do they work? Is this a specific or nonspecific defense?

Watch the Bozeman podcast on The Immune System and answer the following questions.

http://www.youtube.com/watch?v=z3M0vU3Dv8E

NOTE: You need to have YouTube open before clicking on this link at school. If you had to search for this podcast from YouTube, make sure you open “THE IMMUNE SYSTEM” and not just “IMMUNE SYSTEM.”

5. Describe what a virus, such as small pox, does in a human body.

6. Mr. Anderson compares the defense of a castle to the defense of a human body. Complete the following chart of that analogy. Mention three specific parts of the castle and the parts of the human body that correspond and explain why they are similar.

Part of Castle Part of Human Body Explanation of why they are similar Name: ______Date: _____ Period: ____ 2

7. What are 4 ways that skin defends the body from infection? Is this a specific or a nonspecific defense?

8. What is an “antigen”?

9. How was the name “antigen” derived? Carefully draw an antibody and its antigen. Explain how and antibody works to protect the body and explain how the structure of an antibody relates to its function.

10. Explain what it means for a person to have specific immunity to an antigen.

11. What are lymphocytes and what are the two major classes of lymphocytes?

12. Go to: http://www.nobelprize.org/educational/medicine/immunity/immune-detail.html

13. What is the complement system? 14. Name the four things complement proteins can do: a. trigger ______b. attract “eater” cells such as ______c. ______intruders so that eater cells are more likely to devour them d. ______intruders

15. Phagocytes: specialized in “______” bacteria, viruses, and dead or injured body cells a. Which are the “big eaters”? ______b. Why are these called “big eaters”? ______c. What are the other two types of eaters? ______and ______cells

16. Where do lymphocytes originate? ______Where do lymphocytes migrate? ______

17. What are two types of lymphocytes? ______

18. The lymphatic system ______cells into the body and filters out ______and invading organisms such as bacteria.

19. Each lymphocyte has ______that enable it to recognize foreign substances. These receptors are very ______- each can match only ______specific antigen. The lymphocyte cells travel through your body until they find an antigen of the right ______and ______to match their specific receptors. Why does the body produce so many different lymphocytes? ______

20. Why are T cells named “T”cells? ______

21. Helper T cells are the main ______of the human immune defense.

22. What do helper T cells help activate? ______and ______